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1. 发明申请

US20190328961A1 VALVE AND A METHOD FOR ADMINISTERING A PLURALITY OF DRUG FLUIDS 审中-公开
公开(公告)号：US20190328961A1
公开(公告)日：2019-10-31
申请号：US16509854
申请日：2019-07-12
申请人： CYTO365 AB
发明人： Micael Tornblom
IPC分类号： A61M5/168 , F16K11/085 , A61M5/14 , A61M39/24 , A61M39/22
摘要： A valve and a method for administering a plurality of drug fluids to a patient are disclosed. For each drug fluid, the valve may be rotated into a selected drug position associated with the drug fluid. With the valve being in the selected drug position, a backpriming may be performed of a connector line of a drug container containing the drug fluid. Thereafter, the drug fluid may be administered with the valve being in the same selected drug position. Thereafter, the valve may be flushed, optionally while maintaining the same selected valve position.

2. 发明授权

US10960135B2 Valve and a method for administering a plurality of drug fluids 有权
公开(公告)号：US10960135B2
公开(公告)日：2021-03-30
申请号：US16509854
申请日：2019-07-12
申请人： CYTO365 AB
发明人： Micael Tornblom
IPC分类号： A61M5/168 , A61M39/22 , A61M5/14 , F16K11/085 , A61M39/24
摘要： A valve and a method for administering a plurality of drug fluids to a patient are disclosed. For each drug fluid, the valve may be rotated into a selected drug position associated with the drug fluid. With the valve being in the selected drug position, a backpriming may be performed of a connector line of a drug container containing the drug fluid. Thereafter, the drug fluid may be administered with the valve being in the same selected drug position. Thereafter, the valve may be flushed, optionally while maintaining the same selected valve position.

3. 发明授权

US12064587B2 Closed-system type female connector, a method for manufacture, and a stopcock having such female connectors 有权
公开(公告)号：US12064587B2
公开(公告)日：2024-08-20
申请号：US18011822
申请日：2021-06-23
申请人： CYTO365 AB
发明人： Micael Törnblom
IPC分类号： A61M39/26 , A61M39/22
CPC分类号： A61M39/26 , A61M2039/229 , A61M2039/267 , A61M2207/00
摘要： A medical female connector (10) for controlling a fluid flow is disclosed, as well as a method for its manufacturing, and medical devices including such a female connector. A tubular plunger (40) and a flexible valve member (60) are inserted into a housing (20). A distal end (42) of the plunger (40) is located at a distance proximally from the distal end (22) of the housing (20). In a flow stop configuration, the flexible valve member (60) seals a flow path (44) through the tubular plunger (40). In a flow configuration, the valve member (60) is compressed by a male connector (90) and deformed by the plunger (40) to allow a fluid flow through the plunger (40). A frusto-conical female sealing surface (24) is arranged to form a seal with the male connector (90). An entrance opening (25) of the housing (20) presents a diameter equal to or larger than the maximum diameter (d1) of the female sealing surface (24).

4. 发明授权

US10357604B2 Valve and a method for administering a plurality of drug fluids 有权
公开(公告)号：US10357604B2
公开(公告)日：2019-07-23
申请号：US15064422
申请日：2016-03-08
申请人： CYTO365 AB
发明人： Micael Tornblom
IPC分类号： A61M5/14 , A61M39/22 , A61M5/168 , A61M39/24 , F16K11/085
摘要： A valve and a method for administering a plurality of drug fluids to a patient are disclosed. For each drug fluid, the valve may be rotated into a selected drug position associated with the drug fluid. With the valve being in the selected drug position, a backpriming may be performed of a connector line of a drug container containing the drug fluid. Thereafter, the drug fluid may be administered with the valve being in the same selected drug position. Thereafter, the valve may be flushed, optionally while maintaining the same selected valve position.

5. 发明公开

US20230226340A1 A CLOSED-SYSTEM TYPE FEMALE CONNECTOR, A METHOD FOR MANUFACTURE, AND A STOPCOCK HAVING SUCH FEMALE CONNECTORS 审中-公开
公开(公告)号：US20230226340A1
公开(公告)日：2023-07-20
申请号：US18011822
申请日：2021-06-23
申请人： CYTO365 AB
发明人： Micael Törnblom
IPC分类号： A61M39/26
CPC分类号： A61M39/26 , A61M2039/229
摘要： A medical female connector (10) for controlling a fluid flow is disclosed, as well as a method for its manufacturing, and medical devices including such a female connector. A tubular plunger (40) and a flexible valve member (60) are inserted into a housing (20). A distal end (42) of the plunger (40) is located at a distance proximally from the distal end (22) of the housing (20). In a flow stop configuration, the flexible valve member (60) seals a flow path (44) through the tubular plunger (40). In a flow configuration, the valve member (60) is compressed by a male connector (90) and deformed by the plunger (40) to allow a fluid flow through the plunger (40). A frusto-conical female sealing surface (24) is arranged to form a seal with the male connector (90). An entrance opening (25) of the housing (20) presents a diameter equal to or larger than the maximum diameter (d1) of the female sealing surface (24).

6. 发明申请

US20170258991A1 VALVE AND A METHOD FOR ADMINISTERING A PLURALITY OF DRUG FLUIDS 审中-公开
公开(公告)号：US20170258991A1
公开(公告)日：2017-09-14
申请号：US15064422
申请日：2016-03-08
申请人： CYTO365 AB
发明人： Micael Tornblom
IPC分类号： A61M5/168 , A61M39/24 , A61M5/14
CPC分类号： A61M5/16827 , A61M5/1407 , A61M5/1409 , A61M5/16881 , A61M39/223 , A61M39/225 , A61M39/24 , A61M2005/1402 , A61M2005/1403 , A61M2039/229 , F16K11/085
摘要： A valve and a method for administering a plurality of drug fluids to a patient are disclosed. For each drug fluid, the valve may be rotated into a selected drug position associated with the drug fluid. With the valve being in the selected drug position, a backpriming may be performed of a connector line of a drug container containing the drug fluid. Thereafter, the drug fluid may be administered with the valve being in the same selected drug position. Thereafter, the valve may be flushed, optionally while maintaining the same selected valve position.

7. 发明申请

WO2017153362A1 A VALVE AND METHOD FOR ADMINISTERING A PLURALITY OF DRUG FLUIDS 审中-公开
标题翻译：一种用于管理多种药物流体的阀门和方法
公开(公告)号：WO2017153362A1
公开(公告)日：2017-09-14
申请号：PCT/EP2017/055236
申请日：2017-03-07
申请人： CYTO365 AB
发明人： TÖRNBLOM, Micael
IPC分类号： A61M39/22 , F16K11/076 , A61M5/14
摘要： A valve for administering a plurality of drug fluids to a patient is disclosed. For each drug fluid, the valve may be rotated into a selected drug position associated with the drug fluid. With the valve being in the selected drug position, a backpriming may be performed of a connector line of a drug container containing the drug fluid. Thereafter, the drug fluid may be administered with the valve being in the same selected drug position. Thereafter, the valve may be flushed, optionally while maintaining the same selected valve position.
摘要翻译：公开了一种用于向患者施用多种药物流体的阀门。对于每种药物流体，阀可以旋转到与药物流体相关的选定药物位置。在该阀处于选定的药物位置的情况下，可以对包含药物流体的药物容器的连接器管线执行逆流（backpriming）。之后，药物流体可以与处于相同的选定药物位置的瓣膜一起给药。此后，阀门可以被冲洗，可选地保持相同的选定阀门位置。

8. 发明申请

WO2016037648A1 VALVE FOR ADMINISTRATION OF MULTIPLE DRUG FLUIDS 审中-公开
标题翻译：用于管理多种药物流体的阀门
公开(公告)号：WO2016037648A1
公开(公告)日：2016-03-17
申请号：PCT/EP2014/069278
申请日：2014-09-10
申请人： CYTO365 AB
发明人： TÖRNBLOM, Micael
IPC分类号： A61M39/22 , F16K11/076 , F16K11/083 , F16K11/085
CPC分类号： A61M39/223 , A61M39/225 , A61M39/24 , A61M2039/229 , A61M2205/582 , F16K11/083 , F16K11/085
摘要： A drug administration valve (100) comprises a valve housing (200) having a plurality of drug inlets (D1 to D4) for receiving drug fluids, such as cytostatic, one flushing inlet (F) for receiving a flushing fluid, and an outlet (O). A valve member (300) rotationally arranged in the housing has a passageway (320; 321) presenting a single inlet (322) and a single outlet (324).The valve member (300) presents a plurality of drug positions for guiding an associated drug fluid to the outlet (O), and one or more flushing positions for guiding a flushing fluid through the same passageway (320; 321) as the drug fluids in order to flush said passageway (320; 321) from any drug residuals. The valve member (300) is prevented from rotating from one drug position to another drug position without passing one of said flushing positions
摘要翻译：药物给药阀（100）包括具有多个用于接收药液的药物入口（D1至D4）的阀壳体（200），用于接收药液，例如细胞抑制剂，用于接收冲洗流体的一个冲洗入口（F） O）。旋转地布置在壳体中的阀构件（300）具有呈现单个入口（322）和单个出口（324）的通道（320; 321）。阀构件（300）呈现多个药物位置，用于引导相关联药液流到出口（O），以及一个或多个冲洗位置，用于引导冲洗流体通过与药物流体相同的通道（320; 321），以便将任何药物残留物冲洗所述通道（320; 321）。防止阀构件（300）在不通过所述冲洗位置之一的情况下从一个药物位置旋转到另一个药物位置

9. 发明申请

WO2016037646A1 VALVE FOR ADMINISTRATION OF DRUG FLUIDS AND A METHOD FOR CONTROLLING SUCH A VALVE 审中-公开
标题翻译：用于药物流体管理的阀和用于控制这种阀的方法
公开(公告)号：WO2016037646A1
公开(公告)日：2016-03-17
申请号：PCT/EP2014/069275
申请日：2014-09-10
申请人： CYTO365 AB
发明人： TÖRNBLOM, Micael
IPC分类号： A61M39/22 , F16K11/083 , F16K11/085
CPC分类号： A61M39/223 , A61M39/225 , A61M2039/229 , F16K11/0853
摘要： A valve for administration of drug fluids, such as cytostatics, comprises at least one "drug inlet" for receiving a drug fluid and a "saline inlet" for receiving a neutral fluid. In a "drug position" of a valve member (300), the drug inlet is connected to an outlet (230) of the valve via a primary channel (310) of the valve member (300) and there is no connection between the drug inlet and a secondary channel (320) of the valve member (300) and no connection between the drug inlet and the saline inlet. In a priming/flushing position, the saline inlet is connected to the drug inlet via the secondary channel (320) and the drug inlet is connected to the outlet (230) via the primary channel (310).
摘要翻译：用于给药流体例如细胞抑制剂的阀包括用于接收药物流体的至少一个“药物入口”和用于接收中性流体的“盐水入口”。在阀构件（300）的“药物位置”中，药物入口经由阀构件（300）的主通道（310）连接到阀的出口（230），并且药物之间没有连接入口和阀构件（300）的第二通道（320），并且药物入口和盐水入口之间没有连接。在起动/冲洗位置，盐水入口通过第二通道（320）连接到药物入口，药物入口通过主通道（310）连接到出口（230）。

10. 发明申请

WO2021260050A1 A CLOSED-SYSTEM TYPE FEMALE CONNECTOR, A METHOD FOR MANUFACTURE, AND A STOPCOCK HAVING SUCH FEMALE CONNECTORS 审中-公开
公开(公告)号：WO2021260050A1
公开(公告)日：2021-12-30
申请号：PCT/EP2021/067223
申请日：2021-06-23
申请人： CYTO365 AB
发明人： TÖRNBLOM, Micael
IPC分类号： A61M39/26 , A61M2039/267 , A61M2207/00
摘要： A medical female connector (10) for controlling a fluid flow is disclosed, as well as a method for its manufacturing, and medical devices including such a female connector. A tubular plunger (40) and a flexible valve member (60) are inserted into a housing (20). A distal end (42) of the plunger (40) is located at a distance proximally from the distal end (22) of the housing (20). In a flow stop configuration, the flexible valve member (60) seals a flow path (44) through the tubular plunger (40). In a flow configuration, the valve member (60) is compressed by a male connector (90) and deformed by the plunger (40) to allow a fluid flow through the plunger (40). A frusto-conical female sealing surface (24) is arranged to form a seal with the male connector (90). An entrance opening (25) of the housing (20) presents a diameter equal to or larger than the maximum diameter (d1) of the female sealing surface (24).

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