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1. 发明专利

IL279679D0 Laminate fluidic circuit for a fluid cartridge 未知
公开(公告)号：IL279679D0
公开(公告)日：2021-03-01
申请号：IL27967920
申请日：2020-12-22
申请人： ILLUMINA INC , CRIVELLI PAUL , DELATTRE CYRIL
发明人： CRIVELLI PAUL , DELATTRE CYRIL
IPC分类号： B01L3/00 , B29C53/06 , G01N35/10
摘要： An apparatus includes a fluid reservoir and a laminate fluidic circuit positioned above the fluid reservoir. The laminate fluidic circuit includes two or more layers laminated together to define a substantially planar substrate and one or more channels defined within the substrate. The laminate fluidic circuit includes a flexible conduit defined by a portion of the substrate encompassing an extent of at least one of the channels that is partially separated or separable from the remainder of the substrate. The flexible conduit is deflectable with respect to the planar substrate toward the fluid reservoir such that the flexible conduit fluidly connects the at least one channel to the fluid reservoir.

2. 发明专利

IL279426D0 Multi-valve fluid cartridge 未知
公开(公告)号：IL279426D0
公开(公告)日：2021-01-31
申请号：IL27942620
申请日：2020-12-13
申请人： ILLUMINA INC , DREWS BRADLEY KENT , OSMUS JAMES MICHAEL , CRIVELLI PAUL , COX MURANAMI WESLEY
发明人： DREWS BRADLEY KENT , OSMUS JAMES MICHAEL , CRIVELLI PAUL , COX-MURANAMI WESLEY
IPC分类号： B01L3/00
摘要： An apparatus includes a fluidic circuit, a bypass fluidic circuit, a first set of fluid wells, a second set of fluid wells, a first valve, and a second valve. The first valve operatively associated with the first set of fluid wells such that the first selectively fluidly connects any one of the first set of fluid wells to a first valve outlet. The second valve operatively associated with the fluidic circuit, the bypass fluidic circuit, the first valve outlet, and the second set of fluid wells such that the second valve selectively fluidly connects any one of the second set of fluid wells and the first valve outlet to the fluidic circuit or the first valve outlet to the bypass fluidic circuit.

3. 发明专利

IL270849D0 Flow cell with integrated manifold 未知
公开(公告)号：IL270849D0
公开(公告)日：2020-01-30
申请号：IL27084919
申请日：2019-11-23
申请人： ILLUMINA INC , LIN SZ CHIN STEVEN , CRIVELLI PAUL , TAYLOR JAY , RHEE MINSOUNG , FOLEY JENNIFER , COX MURANAMI WESLEY , DELATTRE CYRIL , KHURANA TARUN
发明人： LIN SZ-CHIN STEVEN , CRIVELLI PAUL , TAYLOR JAY , RHEE MINSOUNG , FOLEY JENNIFER , COX-MURANAMI WESLEY , DELATTRE CYRIL , KHURANA TARUN
IPC分类号： B01L20060101
摘要： In one example, a flow cell includes a plurality of inlet ports sized to receive a flow of reagent from one of a plurality of reagents into the flow cell. An outlet port of the flow cell is sized to pass each flow of reagent out of the flow cell. A flow channel of the flow cell is positioned between, and in fluid communication with, each inlet port and the outlet port. The flow channel includes a manifold section and a detection section. The manifold section has a plurality of manifold branches in fluid communication with a common line, wherein each branch is connected to one of each inlet port. The detection section is in fluid communication with the common line and the outlet port. The detection section is operable to perform a plurality of different chemical reactions between the plurality of reagents and analytes positioned in the detection section.

4. 发明专利

IL269172D0 Cartridge with laminated manifold 未知
公开(公告)号：IL269172D0
公开(公告)日：2019-11-28
申请号：IL26917219
申请日：2019-09-08
申请人： ILLUMINA INC , TRAN HAI , SEGALE DARREN , CRIVELLI PAUL
发明人： TRAN HAI , SEGALE DARREN , CRIVELLI PAUL
IPC分类号： B01L20060101
摘要： A circuit with electrical interconnect for external electronic connection and sensor(s) on a die are combined with a laminated manifold to deliver a liquid reagent over an active surface of the sensor(s). The laminated manifold includes fluidic channel(s), an interface between the die and the fluidic channel(s) being sealed. Also disclosed is a method, the method including assembling a laminated manifold including fluidic channel(s), attaching sensor(s) on a die to a circuit, the circuit including an electrical interconnect, and attaching a planarization layer to the circuit, the planarization layer including a cut out for the die. The method further includes placing sealing adhesive at sides of the die, attaching the laminated manifold to the circuit, and sealing an interface between the die and fluidic channel(s).

5. 发明申请

WO2006121975A1 FLUID EJECTION ASSEMBLY 审中-公开
标题翻译：流体喷射装置
公开(公告)号：WO2006121975A1
公开(公告)日：2006-11-16
申请号：PCT/US2006/017627
申请日：2006-05-08
申请人： HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. , RIVAS, Rio , CRIVELLI, Paul , CRUZ-URIBE, Tony , LEBRON, Hector
发明人： RIVAS, Rio , CRIVELLI, Paul , CRUZ-URIBE, Tony , LEBRON, Hector
IPC分类号： B41J2/16
CPC分类号： B41J2/1404 , B41J2/14072 , B41J2/1604 , B41J2/162 , B41J2/1625 , B41J2/1632 , B41J2002/14379
摘要： A fluid ejection assembly includes at least one inner layer (50/150/250) having a fluid passage (154/254) defined therein, first and second outer layers (30/40) positioned on opposite sides of the at least one inner layer, and an orifice plate (100/100') provided along an edge (34/44) of the first and second outer layers. The first and second outer layers each have a side (32/42) adjacent the at least one inner layer and include drop ejecting elements (70) formed on the side and fluid pathways (80) communicated with the drop ejecting elements. As such, the fluid pathways of the first and second outer layers communicate with the fluid passage of the at least one inner layer. In addition, the orifice plate includes a first row (104) of orifices (102) communicated with the fluid pathways of the first outer layer and a second row (106) of orifices (102) communicated with the fluid pathways of the second outer layer.
摘要翻译：流体喷射组件包括至少一个具有限定在其中的流体通道（154/254）的内层（50/150/250），位于所述至少一个内层的相对侧上的第一和第二外层（30/40），以及沿着第一和第二外层的边缘（34/44）设置的孔板（100/100'）。第一和第二外层各自具有邻近至少一个内层的侧面（32/42），并且包括形成在侧面的液滴喷射元件（70）和与液滴喷射元件连通的流体路径（80）。这样，第一和第二外层的流体路径与至少一个内层的流体通道连通。此外，孔板包括与第一外层的流体通道连通的孔口（102）的第一排（104）和与第二外层的流体通道连通的孔口（102）的第二排（106）。

6. 发明申请

WO2005007412A1 FLUID EJECTION ASSEMBLY 审中-公开
标题翻译：流体喷射装置
公开(公告)号：WO2005007412A1
公开(公告)日：2005-01-27
申请号：PCT/US2004/020677
申请日：2004-06-25
申请人： HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. , HOCK, Scott W. , LEBRON, Hector , CRIVELLI, Paul , DIEST, Kenneth
发明人： HOCK, Scott W. , LEBRON, Hector , CRIVELLI, Paul , DIEST, Kenneth
IPC分类号： B41J2/14
CPC分类号： B41J2/14072 , B41J2/1404 , B41J2002/14379
摘要： A fluid ejection assembly includes at least one inner layer (50/150/250) having a fluid passage (154/254) defined therein, and first and second outer layers (30/40) positioned on opposite sides of the at least one inner layer. The first and second outer layers each have a side (32/42) adjacent the at least one inner layer and include drop ejecting elements (70) formed on the side and fluid pathways (80) communicated with the drop ejecting elements. The fluid pathways of the first and second outer layers communicate with the fluid passage of the at least one inner layer, and the at least one inner layer and the fluid pathways of the first outer layer form a first row (61) of nozzles (13), and the at least one inner layer and the fluid pathways of the second outer layer form a second row (62) of nozzles (13).
摘要翻译：流体喷射组件包括至少一个具有限定在其中的流体通道（154/254）的内层（50/150/250）和位于至少一个内部的相对侧上的第一和第二外层（30/40）层。第一和第二外层各自具有邻近至少一个内层的侧面（32/42），并且包括形成在侧面的液滴喷射元件（70）和与液滴喷射元件连通的流体路径（80）。第一和第二外层的流体通道与至少一个内层的流体通道连通，并且第一外层的至少一个内层和流体通道形成第一排（61）的喷嘴（13）），并且第二外层的至少一个内层和流体通道形成喷嘴（13）的第二排（62）。

7. 发明申请

WO2006115810A1 FLUID EJECTION ASSEMBLY 审中-公开
标题翻译：流体喷射装置
公开(公告)号：WO2006115810A1
公开(公告)日：2006-11-02
申请号：PCT/US2006/013887
申请日：2006-04-13
申请人： HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. , LEBRON, Hector , CRIVELLI, Paul , HOCK, Scott, W.
发明人： LEBRON, Hector , CRIVELLI, Paul , HOCK, Scott, W.
IPC分类号： B41J2/14
CPC分类号： B41J2/1408 , B41J2002/14177 , B41J2002/14379
摘要： A fluid ejection assembly includes a first layer (50/150/250), and a second layer (30/40) positioned on a side of the first layer. The second layer has a side (32/42) adjacent the side of the first layer and includes barriers (82) defining a fluid chamber (80) on the side, a drop ejecting element (70) formed within the fluid chamber, and a thermal conduction path (198) extended between the fluid chamber and the barriers.
摘要翻译：流体喷射组件包括第一层（50/150/250）和位于第一层侧面上的第二层（30/40）。第二层具有与第一层侧相邻的一侧（32/42），并且包括在侧面限定流体室（80）的屏障（82），形成在流体室内的液滴喷射元件（70）热传导路径（198）在流体室和屏障之间延伸。

8. 发明申请

WO2004069412A1 MICROFLUIDIC DEVICE WITH THIN-FILM ELECTRONIC DEVICES 审中-公开
标题翻译：具有薄膜电子器件的微流体器件
公开(公告)号：WO2004069412A1
公开(公告)日：2004-08-19
申请号：PCT/US2004/002435
申请日：2004-01-28
申请人： HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. , PEASE, Grant , GHOZEIL, Adam, L. , DUNFIELD, John, Stephen , CHILDERS, Winthrop, D. , TYVOLL, David , SEXTON, Douglas, A. , CRIVELLI, Paul
发明人： PEASE, Grant , GHOZEIL, Adam, L. , DUNFIELD, John, Stephen , CHILDERS, Winthrop, D. , TYVOLL, David , SEXTON, Douglas, A. , CRIVELLI, Paul
IPC分类号： B01L3/00
CPC分类号： B01L7/525 , B01L3/5027 , B01L3/502715 , B01L2200/10 , B01L2200/147 , B01L2300/024 , B01L2300/0816 , B01L2300/0874 , B01L2300/1827 , B01L2300/1883 , B01L2400/0415 , Y10T436/11 , Y10T436/2575
摘要： A microfluidic device (90) for analysis of a sample. The microfluidic device includes a substrate portion (94) that at least partially defines a chamber (102) for receiving the sample. The substrate portion (94) includes a substrate (98) having a surface (96). The substrate portion (94) also includes a plurality of thin-film layers (110) formed on the substrate (98) adjacent the surface (96). The thin-film layers (110) form a plurality of electronic devices. Each of at least two of the electronic devices is formed by a different set of the thin-film layers (110). The at least two electronic devices may include 1) a temperature control device for controlling the temperature of fluid in the chamber (102), and 2) an other electronic device configured to sense or modify a property of fluid in the chamber (102).
摘要翻译：一种用于分析样品的微流体装置（90）。微流体装置包括至少部分地限定用于接收样品的室（102）的基底部分（94）。衬底部分（94）包括具有表面（96）的衬底（98）。衬底部分（94）还包括在邻近表面（96）的基底（98）上形成的多个薄膜层（110）。薄膜层（110）形成多个电子装置。至少两个电子器件中的每一个由不同的薄膜层组合（110）形成。所述至少两个电子装置可以包括：1）用于控制所述腔室（102）中的流体温度的温度控制装置，以及2）构造成感测或改变所述腔室（102）中的流体性质的另一电子装置。

9. 发明专利

IL271267D0 Flow cell with flexible connection 未知
公开(公告)号：IL271267D0
公开(公告)日：2020-01-30
申请号：IL27126719
申请日：2019-12-08
申请人： ILLUMINA INC , HAGE MATTHEW WILLIAM , SEGALE DARREN , CRIVELLI PAUL , TAYLOR JAY , RHEE MINSOUNG , FOLEY JENNIFER , COX MURANAMI WESLEY , DELATTRE CYRIL , LIU JEFFREY , PAIK PHILIP , ALLEGOREN ERIK , HERTZOG DAVID , MOROZ SMIETANA ALEX , MA XIAOXIAO , TAKAHASHI TSUKASA , WESTERBERG BRANDON
发明人： HAGE MATTHEW WILLIAM , SEGALE DARREN , CRIVELLI PAUL , TAYLOR JAY , RHEE MINSOUNG , FOLEY JENNIFER , COX-MURANAMI WESLEY , DELATTRE CYRIL , LIU JEFFREY , PAIK PHILIP , ALLEGOREN ERIK , HERTZOG DAVID , MOROZ-SMIETANA ALEX , MA XIAOXIAO , TAKAHASHI TSUKASA , WESTERBERG BRANDON
IPC分类号： B01L20060101
摘要： An instrument includes a reagent management system. The reagent management system includes a plurality of reagent wells, each reagent well operable to contain a reagent of a plurality of reagents positioned therein. The reagent management system is operable to select a flow of reagent from one of the plurality of reagents. A flexible connection includes a laminate stack and includes a first flexible channel in fluid communication with the reagent management system. The first flexible channel is operable to route the flow of reagent therethrough. A flow cell includes a flow channel in fluid communication with the first flexible channel. The flow channel is operable to route the flow of reagent over analytes positioned in the flow channel. The flexible connection enables the flow cell to be moved by the instrument relative to a fixed reference point in the instrument.

10. 发明专利

IL271069D0 Fluid caching 未知
公开(公告)号：IL271069D0
公开(公告)日：2020-01-30
申请号：IL27106919
申请日：2019-12-01
申请人： ILLUMINA INC , ILLUMINA CAMBRIDGE LTD , CRIVELLI PAUL , COX MURANAMI WESLEY , KHURANA TARUN , SEGALE DARREN ROBERT , MILLER OLIVER JON , FOLEY JENNIFER OLIVIA , WATTS GARY
发明人： CRIVELLI PAUL , COX-MURANAMI WESLEY , KHURANA TARUN , SEGALE DARREN ROBERT , MILLER OLIVER JON , FOLEY JENNIFER OLIVIA , WATTS GARY
IPC分类号： B01L20060101
摘要： An apparatus for directing fluid into and out of a fluidic device includes two or more fluid prime channels connected to a fluid inlet of the fluidic device, a flow control valve for each fluid prime channel to control flow between the fluid prime channel and the fluid inlet, one or more outlet channels connected to a fluid outlet of the fluidic device, and a flow control valve for each outlet channel to control flow between the fluid outlet and the associated outlet channel. An apparatus for delivering fluids to a fluid inlet includes a plate that is rotatable about an axis of rotation and a plurality of fluid compartments disposed on the plate, each compartment having a fluid exit port disposed at a common radial distance from the axis of rotation and positioned to align with the fluid inlet as the plate rotates about the axis of rotation.

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