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1. 发明公开

EP0435929A1 ELECTRO-SURGICAL APPARATUS FOR REMOVING TUMOURS FROM HOLLOW ORGANS OF THE BODY 失效
标题翻译： ELECTRO-手术单位用于清除体内空腔脏器的肿瘤。
公开(公告)号：EP0435929A1
公开(公告)日：1991-07-10
申请号：EP89910906.0
申请日：1989-09-25
申请人： CONSIDINE, John , Bunce, Colin John
发明人： CONSIDINE, John , Bunce, Colin John
IPC分类号： A61B18 , A61B1 , A61M1 , A61B17
CPC分类号： A61B18/14 , A61B18/1482 , A61B18/1485 , A61B2017/00473 , A61B2018/00107 , A61B2018/00196 , A61B2018/00982 , A61B2018/1407 , A61B2218/002 , A61M1/0039 , A61M1/0047 , A61M1/0056 , A61M1/0064
摘要： Est décrit un endoscope s'utilisant pour enlever des tumeurs dans des organes creux du corps tels que la vessie. L'endoscope consiste en une gaine (49) à travers laquelle s'étend un télescope (46) et en un tube diathermique d'aspiration (31) dont l'extrémité non opératoire (33) communique avec un dispositif d'aspiration. Des éléments (51, 52) sont prévus pour permettre le passage d'un fluide d'irrigation à travers l'endoscope. Le tube de diathermie (31) peut être un tube plastique souple (2, 61) et la pointe d'électrode de diathermie (7, 8) peut être formée d'un fil de résistance électroconducteur relié (5, 39, 63) à une machine de diathermie. La pointe d'électrode est adjacente à une ouverture (41) au niveau de l'extrémité opératoire du tube, les tissus pouvant être immédiatement éliminés par aspiration après sectionnement par la pointe d'électrode. Le degré d'aspiration appliqué au tube (31) est modulé par un espace creux digital (38a) situé au niveau ou à proximité de l'extrémité (33) du tube (31). Dans une variante, le tube (31) peut être formé d'un tube métallique (34) revêtu d'un matériau plastique isolant (35) et possédant une pointe coupante ou coagulatrice (34a), des éléments (37, 38, 43, 45, 53, 54) étant prévus pour animer le tube d'un mouvement alternatif montant et descendant le long de l'endoscope.

2. 发明授权

EP0435929B1 ELECTRO-SURGICAL APPARATUS FOR REMOVING TUMOURS FROM HOLLOW ORGANS OF THE BODY 失效
标题翻译： ELECTRO-手术单位用于清除体内空腔脏器的肿瘤。
公开(公告)号：EP0435929B1
公开(公告)日：1995-01-18
申请号：EP89910906.0
申请日：1989-09-25
申请人： CONSIDINE, John , Bunce, Colin John
发明人： CONSIDINE, John , Bunce, Colin John
IPC分类号： A61B17/39
CPC分类号： A61B18/14 , A61B18/1482 , A61B18/1485 , A61B2017/00473 , A61B2018/00107 , A61B2018/00196 , A61B2018/00982 , A61B2018/1407 , A61B2218/002 , A61M1/0039 , A61M1/0047 , A61M1/0056 , A61M1/0064
摘要： Disclosed is an endoscope for use in the removal of tumours from hollow body organs such as the bladder. The endoscope consists of sheath (49) through which extends a telescope (46) and a suction diathermy tube (31) the non-operation end (33) of which communicates with a suction device. Provision (51, 52) is made for an irrigation fluid to be passed through the endoscope. The diathermy tube (31) may be a flexible plastics tube (2, 61) and the diathermy electrode tip (7, 8) may be formed from electrically conducting resistance wire connected (5, 39, 63) to a diathermy machine. The electrode tip is found adjacent an aperture (41) at the operative of the tube whereby tissue can be immediately removed by suction after severance by the electrode tip. The degree of suction applied to tube (31) being controlled by a finger hole (38a) located at or near the end (33) of the tube (31). Alternatively the tube (31) may be formed of a metal tube (34) coated with an insulating plastics material (35) and having a cutting or coagulating tip (34a), provision (37, 38, 43, 45, 53, 54) being made for reciprocating the tube up and down the endoscope.

3. 发明申请

WO2005123664A2 PROCESSES FOR THE PREPARATION OF 2-CYANO-3-NAPHTHALENE-1-YL-ACRYLIC ACID ALKYL OR BENZYL ESTERS 审中-公开
标题翻译：制备2-氰基-3-萘磺酸-1-乙酰丙酸或苯甲酸酯的方法
公开(公告)号：WO2005123664A2
公开(公告)日：2005-12-29
申请号：PCT/US2005/020182
申请日：2005-06-09
申请人： WYETH , LIU, Weiguo , CONSIDINE, John, L. , DING, Zhixian , POTOSKI, John
发明人： LIU, Weiguo , CONSIDINE, John, L. , DING, Zhixian , POTOSKI, John
IPC分类号： C07C253/30
CPC分类号： C07C253/30 , C07C255/41
摘要： The present invention provides processes for the preparation of compounds of Formula III that are useful in the preparation of pharmaceuticals for the treatment of inflammatory diseases.
摘要翻译：本发明提供了可用于制备用于治疗炎性疾病的药物的式III化合物的方法。

4. 发明申请

WO2005123663A1 PROCESSES FOR THE PREPARATION OF 2-CYANO-3-NAPHTHALENE-1-YL-3-PHENYL-PROPIONIC ACID ALKYL OR BENZYL ESTERS 审中-公开
标题翻译：制备2-氰基-3-萘磺酸-1-基-3-苯基 - 丙酸酸或苄基酯的方法
公开(公告)号：WO2005123663A1
公开(公告)日：2005-12-29
申请号：PCT/US2005/020181
申请日：2005-06-09
申请人： WYETH , LIU, Weiguo , CONSIDINE, John, L. , DING, Zhixian , POTOSKI, John
发明人： LIU, Weiguo , CONSIDINE, John, L. , DING, Zhixian , POTOSKI, John
IPC分类号： C07C253/30
CPC分类号： C07C255/41 , C07C253/30
摘要： The present invention provides processes for the preparation of compounds of Formula (1), which are useful in the preparation of pharmaceuticals for the treatment of inflammatory diseases. The compounds of Formula (I) are also useful as pharmaceuticals.
摘要翻译：本发明提供制备式（1）化合物的方法，其可用于制备用于治疗炎性疾病的药物。式（I）的化合物也可用作药物。

5. 发明专利

DE68920747D1 未知
公开(公告)号：DE68920747D1
公开(公告)日：1995-03-02
申请号：DE68920747
申请日：1989-09-25
申请人： CONSIDINE JOHN , BUNCE COLIN JOHN
发明人： CONSIDINE JOHN , BUNCE COLIN JOHN
IPC分类号： A61B18/04 , A61B1/00 , A61B17/00 , A61B18/00 , A61B18/14 , A61M1/00 , A61B17/39
摘要： Disclosed is an endoscope for use in the removal of tumours from hollow body organs such as the bladder. The endoscope consists of sheath (49) through which extends a telescope (46) and a suction diathermy tube (2, 31, 60) the non-operation end (3, 33) of which communicates with a suction device. Provision (51, 52) is made for an irrigation fluid to be passed through the endoscope. The diathermy tube (2, 31 60) may be a flexible plastics tube (2, 61) and the diathermy electrode tip (7, 8) may be formed from electrically conducting resistance wire connected (5, 39, 63) to a diathermy machine. The electrode tip is found adjacent an aperture (4, 9, 41) at the operative of the tube whereby tissue can be immediately removed by suction after severance by the electrode tip. The degree of suction applied to the tube (2, 31 61) being controlled by a finger hole (38a+B, 55, 66) located at or near the end (3, 33) of the tube (2, 31, 61). Alternatively the tube (31) may be formed of a metal tube (34) coated with an insulating plastics material (35) and having a cutting or coagulating tip (34a), provision (37, 38, 43 45, 53, 54) being made for reciprocating the tube up and down the endoscope.

6. 发明申请

WO2007024859A2 PROCESS FOR PREPARING BETA-LACTAMASE INHIBITORS 审中-公开
标题翻译：制备β-乳酸酶抑制剂的方法
公开(公告)号：WO2007024859A2
公开(公告)日：2007-03-01
申请号：PCT/US2006/032781
申请日：2006-08-22
申请人： WYETH , MICHALAK, Ronald, S. , GALANTE, Rocco , BLUM, David, M. , ROUTEL, Lisa , DURUTLIC, Haris , GUINOSSO, Charles , CONSIDINE, John , KREMER, Ken
发明人： MICHALAK, Ronald, S. , GALANTE, Rocco , BLUM, David, M. , ROUTEL, Lisa , DURUTLIC, Haris , GUINOSSO, Charles , CONSIDINE, John , KREMER, Ken
CPC分类号： C07D513/04 , C07D277/60
摘要： The present invention relates to processes for preparing β-alkylidene penem derivatives that can be important as broad spectrum β-lactamase inhibitors and anti-bacterial agents.
摘要翻译：本发明涉及制备β-亚烷基半乳聚糖衍生物的方法，其可以作为广谱β-内酰胺酶抑制剂和抗菌剂是重要的。

7. 发明申请

WO0237300A9 SWITCHING SYSTEM 审中-公开
标题翻译：开关系统
公开(公告)号：WO0237300A9
公开(公告)日：2003-01-03
申请号：PCT/US0145637
申请日：2001-11-02
申请人： PIRUS NETWORKS , CONSIDINE JOHN , HALL HOWARD , COCHRANE CHRISTOPHER
发明人： CONSIDINE JOHN , HALL HOWARD , COCHRANE CHRISTOPHER
IPC分类号： H04L12/18 , H04L12/46 , H04L29/06 , H04L29/08 , H04L29/12 , G06F15/16
CPC分类号： H04L29/12009 , H04L29/12018 , H04L61/10 , H04L63/0272 , H04L63/102 , H04L67/1002 , H04L67/1008 , H04L67/1017 , H04L67/1097 , H04L67/38 , H04L67/42 , H04L69/10 , H04L69/12 , H04L69/16 , H04L69/161 , H04L69/163 , H04L69/164 , H04L69/18 , H04L69/22 , H04L69/32 , H04L69/329 , H04L2029/06054
摘要： A system and method for provided a switch system (100) having a first configurable set of processor elements (102) to process storage resource connection requests (104), a second configurable set of processor elements capable of communications with the first configurable set of processor elements (102) to receive, from the first configurable set of processor elements, storage connection requests representative of client requests, and to route the requests to at least one of the storage elements (104), and a configurable switching fabric (106) interconnected between the first and second sets of processor elements (102), for receiving at least a first storage connection request (104) from one of the first set of processor elements (102), determining an appropriate one of the second set of processors for processing the storage connection request (104), automatically configuring the storage connection request in accordance with a protocol utilized by the selected one of the second set of processors, and forwarding the storage connection request to the selected one of the second set of processors for routing to at least one of the storage elements.
摘要翻译：一种用于提供具有处理存储资源连接请求（104）的处理器元件（102）的第一可配置集合的交换机系统（100）的系统和方法，能够与所述第一可配置集合处理器通信的第二可配置处理器组集合元件（102），用于从所述第一可配置的处理器元件组接收表示客户端请求的存储连接请求，并且将所述请求路由到所述存储元件（104）中的至少一个以及互连的可配置交换结构（106）在第一和第二组处理器元件（102）之间，用于从第一组处理器元件（102）中的一个接收至少第一存储连接请求（104），确定用于处理的第二组处理器中的适当的一个所述存储连接请求（104）根据所选择的第二组p中所选择的协议自动地配置所述存储连接请求并且将所述存储连接请求转发到所述第二组处理器中的所选择的一个，用于路由到所述存储元件中的至少一个。

8. 发明申请

WO2005123664A3 PROCESSES FOR THE PREPARATION OF 2-CYANO-3-NAPHTHALENE-1-YL-ACRYLIC ACID ALKYL OR BENZYL ESTERS 审中-公开
标题翻译：制备2-氰基-3-萘磺酸-1-乙酰丙酸或苯甲酸酯的方法
公开(公告)号：WO2005123664A3
公开(公告)日：2006-07-13
申请号：PCT/US2005020182
申请日：2005-06-09
申请人： WYETH CORP , LIU WEIGUO , CONSIDINE JOHN L , DING ZHIXIAN , POTOSKI JOHN
发明人： LIU WEIGUO , CONSIDINE JOHN L , DING ZHIXIAN , POTOSKI JOHN
IPC分类号： C07C253/30 , C07C255/41
CPC分类号： C07C253/30 , C07C255/41
摘要： The present invention provides processes for the preparation of compounds of Formula III that are useful in the preparation of pharmaceuticals for the treatment of inflammatory diseases.
摘要翻译：本发明提供了可用于制备用于治疗炎性疾病的药物的式III化合物的方法。

9. 发明申请

WO2004066919A2 SYNTHESIS OF 4AMINO-2-BUTENOYL CHLORIDES AND THEIR USE IN THE PREPARATION OF 3-CYANO QUINOLINES 审中-公开
标题翻译： 4氨基二氨基氯化物的合成及其在3-氰基喹啉的制备中的应用
公开(公告)号：WO2004066919A2
公开(公告)日：2004-08-12
申请号：PCT/US2004/001133
申请日：2004-01-16
申请人： WYETH , CONSIDINE, John, Leo , DAIGNEAULT, Sylvain , CHEW, Warren , IERA, Silvio , DUNCAN, Scott, Mason , REN, Jianxin
发明人： CONSIDINE, John, Leo , DAIGNEAULT, Sylvain , CHEW, Warren , IERA, Silvio , DUNCAN, Scott, Mason , REN, Jianxin
IPC分类号： A61K
CPC分类号： C07C231/02 , C07C229/30
摘要： This invention provides a compound of Formula (I) wherein S 1 , and S 2 are each independently, hydrogen, alkyl, alkenyl, alkynyl, aralkyl, substituted or unsubstituted aryl, and S 1 , and S 2 together with the nitrogen to which they are attached form a nitrogen containing heteroaryl and a pharmaceutically acceptable salt thereof; a method of preparing the compound of Formula (I), and use of the compound of Formula (I) in the preparation of 3-cyano quinolines.
摘要翻译：本发明提供式（I）的化合物，其中S1和S2各自独立地为氢，烷基，烯基，炔基，芳烷基，取代或未取代的芳基，并且S1和S2与它们所连接的氮一起形成含氮杂芳基及其药学上可接受的盐; 制备式（I）化合物的方法，以及式（I）化合物在3-氰基喹啉的制备中的用途。

10. 发明申请

WO1990003152A1 ELECTRO-SURGICAL APPARATUS FOR REMOVING TUMOURS FROM HOLLOW ORGANS OF THE BODY 审中-公开
标题翻译：用于从身体中部器官移除肿瘤的电外科手术
公开(公告)号：WO1990003152A1
公开(公告)日：1990-04-05
申请号：PCT/GB1989001124
申请日：1989-09-25
申请人： CONSIDINE, John , COLIN, John, Bunce
IPC分类号： A61B17/39
CPC分类号： A61B18/14 , A61B18/1482 , A61B18/1485 , A61B2017/00473 , A61B2018/00107 , A61B2018/00196 , A61B2018/00982 , A61B2018/1407 , A61B2218/002 , A61M1/0039 , A61M1/0047 , A61M1/0056 , A61M1/0064
摘要： Disclosed is an endoscope for use in the removal of tumours from hollow body organs such as the bladder. The endoscope consists of sheath (49) through which extends a telescope (46) and a suction diathermy tube (31) the non-operation end (33) of which communicates with a suction device. Provision (51, 52) is made for an irrigation fluid to be passed through the endoscope. The diathermy tube (31) may be a flexible plastics tube (2, 61) and the diathermy electrode tip (7, 8) may be formed from electrically conducting resistance wire connected (5, 39, 63) to a diathermy machine. The electrode tip is found adjacent an aperture (41) at the operative of the tube whereby tissue can be immediately removed by suction after severance by the electrode tip. The degree of suction applied to tube (31) being controlled by a finger hole (38a) located at or near the end (33) of the tube (31). Alternatively the tube (31) may be formed of a metal tube (34) coated with an insulating plastics material (35) and having a cutting or coagulating tip (34a), provision (37, 38, 43, 45, 53, 54) being made for reciprocating the tube up and down the endoscope.
摘要翻译：公开了一种用于从诸如膀胱的中空身体器官中去除肿瘤的内窥镜。内窥镜包括护套（49），通过该护套延伸望远镜（46）和吸入透热管（31），其非操作端（33）与抽吸装置连通。设置（51,52）用于通过内窥镜的冲洗流体。透热管（31）可以是柔性塑料管（2,61），并且透热电极头（7,8）可以由连接到透热机的导电电阻丝（5,39,63）形成。发现电极尖端在管的操作处邻近孔（41），由此在通过电极尖端分离之后可以通过抽吸立即去除组织。通过位于管（31）的端部（33）处或附近的指孔（38a）来控制施加到管（31）的抽吸程度。或者，管（31）可以由涂覆有绝缘塑料材料（35）并具有切割或凝固尖端（34a）的金属管（34）形成，提供（37,38,43,45,53,54）用于使管内上下往复运动。

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