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1. 发明申请

WO2009134339A8 GENES AND USES FOR PLANT ENHANCEMENT 审中-公开
标题翻译：植物增强的基因和用途
公开(公告)号：WO2009134339A8
公开(公告)日：2013-06-13
申请号：PCT/US2009002547
申请日：2009-04-24
申请人： MONSANTO TECHNOLOGY LLC , COFFIN MARIE
发明人： COFFIN MARIE
IPC分类号： C12N15/82 , A01H5/00
CPC分类号： C12N15/90 , C12N15/8209 , C12N15/8241 , C12N15/8247 , C12N15/8251 , C12N15/8261 , C12N15/8271 , C12N15/8273 , C12N15/8274 , C12N15/8275 , Y02A40/146
摘要： Transgenic seed for crops with enhanced agronomic traits are provided by trait- improving recombinant DNA in the nucleus of cells of the seed where plants grown from such transgenic seed exhibit one or more enhanced traits as compared to a control plant. Of particular interest are transgenic plants that have increased yield. The present invention also provides recombinant DNA molecules for expression of a protein, and recombinant DNA molecules for suppression of a protein.
摘要翻译：具有增强的农艺性状的作物的转基因种子通过在种子细胞核中改良重组DNA来提供，其中与对照植物相比，从这种转基因种子生长的植物表现出一种或多种增强的性状。特别感兴趣的是具有增加的产量的转基因植物。本发明还提供了用于表达蛋白质的重组DNA分子和用于抑制蛋白质的重组DNA分子。

2. 发明申请

WO2010075143A1 GENES AND USES FOR PLANT ENHANCEMENT 审中-公开
标题翻译：植物增强的基因和用途
公开(公告)号：WO2010075143A1
公开(公告)日：2010-07-01
申请号：PCT/US2009/068351
申请日：2009-12-17
申请人： MONSANTO TECHNOLOGY LLC , COFFIN, Marie
发明人： COFFIN, Marie
IPC分类号： C12N15/82 , A01H5/00
CPC分类号： C12N15/8273 , A01H1/02 , A01H5/10 , C12N15/8209 , C12N15/8247 , C12N15/8251 , C12N15/8261 , C12N15/8271 , C12N15/8274 , C12Q1/6895 , C12Q2600/13 , C12Q2600/158 , Y02A40/146
摘要： The present invention discloses transgenic seeds for crops with enhanced agronomic traits are provided by trait-improving recombinant DNA in the nucleus of cells of the seed where plants grown from such transgenic seed exhibit one or more enhanced traits as compared to a control plant. Of particular interest are transgenic plants that have increased yield. The present invention also provides recombinant DNA molecules for expression of a protein, and recombinant DNA molecules for suppression of a protein.
摘要翻译：本发明公开了具有增强农学性状的作物的转基因种子，其通过在种子细胞核中改良重组DNA提供，其中与对照植物相比，从这种转基因种子生长的植物表现出一种或多种增强的性状。特别感兴趣的是具有增加的产量的转基因植物。本发明还提供了用于表达蛋白质的重组DNA分子和用于抑制蛋白质的重组DNA分子。

3. 发明申请

WO2006138005A8 GENES AND USES FOR PLANT IMPROVEMENT 审中-公开
标题翻译：用于植物改良的基因和用途
公开(公告)号：WO2006138005A8
公开(公告)日：2008-12-11
申请号：PCT/US2006018535
申请日：2006-05-10
申请人： MONSANTO TECHNOLOGY LLC , ABAD MARK SCOTT , AGBOOLA RUTH , MCDONALD MARIA , RICH RONALD C , SLATEN ERIN , GOLDMAN BARRY S , SHAIKH FATEN , CHELF FRANCES , DARVEAUX BETTINA , COFFIN MARIE
发明人： ABAD MARK SCOTT , AGBOOLA RUTH , MCDONALD MARIA , RICH RONALD C , SLATEN ERIN , GOLDMAN BARRY S , SHAIKH FATEN , CHELF FRANCES , DARVEAUX BETTINA , COFFIN MARIE
IPC分类号： A01H1/00 , A01H5/00 , C12N5/04 , C12N15/82
CPC分类号： C12N15/8273 , C07K14/415 , C12N15/8241 , C12N15/8243 , C12N15/8247 , C12N15/8251 , C12N15/8261 , Y02A40/146
摘要： Transgenic seed for crops with improved traits are provided by trait-improving recombinant DNA in the nucleus of cells of the seed where plants grown from such transgenic seed exhibit one or more improved traits as compared to a control plant. Of particular interest are transgenic plants that have increased yield. The present invention also provides recombinant DNA molecules for expression of a protein, and recombinant DNA molecules for suppression of a protein.
摘要翻译：具有改良性状的作物的转基因种子由种子细胞核中的性状改良重组DNA提供，与对照植物相比，由此类转基因种子生长的植物表现出一种或多种改善的性状。特别感兴趣的是具有增加的产量的转基因植物。本发明还提供了用于表达蛋白质的重组DNA分子和用于抑制蛋白质的重组DNA分子。

4. 发明申请

WO2004114081A2 METHODS AND SYSTEMS FOR CREATION OF A COHERENCE DATABASE 审中-公开
标题翻译：创建相关数据库的方法和系统
公开(公告)号：WO2004114081A2
公开(公告)日：2004-12-29
申请号：PCT/US2004/019471
申请日：2004-06-18
申请人： PARADIGM GENETICS, INC. , COFFIN, Marie , LAWRENCE, Matthew
发明人： COFFIN, Marie , LAWRENCE, Matthew
IPC分类号： G06F
CPC分类号： G06F17/30292
摘要： The present invention provides methods and systems for organizing complex biological data in a database schema that facilitates data analysis in a biological context. Specifically, the methods and systems of the present invention pertain to the creation of an integrated relational database schema for recording and organizing summary data from experiments, relating data from disparate data streams, and relating data to reference information sources. The invention is useful in multiple applications, including applications in the agricultural, pharmaceutical, forensic, biotechnology, and nutriceutical industries.
摘要翻译：本发明提供了用于在数据库模式中组织复杂生物数据的方法和系统，该数据库模式有利于生物语境中的数据分析。具体地，本发明的方法和系统涉及创建用于记录和组织来自实验的汇总数据的综合关系数据库模式，将来自不同数据流的数据与相关数据相关联到参考信息源。本发明在多种应用中有用，包括在农业，制药，法医，生物技术和营养行业的应用。

5. 发明申请

WO2009073069A2 GENES AND USES FOR PLANT ENHANCEMENT 审中-公开
标题翻译：植物增强的基因和用途
公开(公告)号：WO2009073069A2
公开(公告)日：2009-06-11
申请号：PCT/US2008/012175
申请日：2008-10-27
申请人： MONSANTO TECHNOLOGY, LLC , BOHANNON, Maria, C. , COFFIN, Marie , SHAIKH, Faten , WINSLOW, Amanda
发明人： BOHANNON, Maria, C. , COFFIN, Marie , SHAIKH, Faten , WINSLOW, Amanda
IPC分类号： C12N15/82 , A01H5/00 , A01H5/10
CPC分类号： C12N15/8275 , A01H1/04 , C07K14/415 , C12N15/8241 , C12N15/8247 , C12N15/8261 , C12N15/8262 , C12N15/8273 , C12N15/8274 , C12Q1/6895 , C12Q2600/13 , Y02A40/146
摘要： Transgenic seed for crops with enhanced agronomic traits are provided by trait-improving recombinant DNA in the nucleus of cells of the seed where plants grown from such transgenic seed exhibit one or more enhanced traits as compared to a control plant. Of particular interest are transgenic plants that have increased yield. The present invention also provides recombinant DNA molecules for expression of a protein, and recombinant DNA molecules for suppression of a protein.
摘要翻译：具有增强的农学性状的作物的转基因种子由种子细胞核中的改良重组DNA提供，其中与对照植物相比，从这种转基因种子生长的植物表现出一种或多种增强的性状。特别感兴趣的是具有增加的产量的转基因植物。本发明还提供了用于表达蛋白质的重组DNA分子和用于抑制蛋白质的重组DNA分子。

6. 发明申请

WO2005062844A2 SYSTEM AND METHODS FOR NON-TARGETED PROCESSING OF CHROMATOGRAPHIC DATA 审中-公开
标题翻译：用于非定向处理色谱数据的系统和方法
公开(公告)号：WO2005062844A2
公开(公告)日：2005-07-14
申请号：PCT/US2004/042876
申请日：2004-12-17
申请人： ICORIA, INC. , WINFIELD, Stephanie , HAAS, William, David , COFFIN, Marie
发明人： WINFIELD, Stephanie , HAAS, William, David , COFFIN, Marie
IPC分类号： G01N33/48 , G01N33/50 , G06F19/00
CPC分类号： G06F19/24
摘要： Methods are provided for non-targeted processing of hyphenated chromatographic data, such that even when the data represent a complex mixture of unknown components, a comprehensive number of the components are detected with minimal information loss and introduction of error. Processing hyphenated chromatographic data by the present methods is compatible with use of subsequent algorithms for chromatographic information extraction, and enhances the accuracy of a subsequent peak/component picking program. The present methods comprise subjecting data collected using a hyphenated chromatographic technique like GC-MS or LC-MS, i.e., data having a continuous or non-discrete dimension (e.g. mass ) to an algorithm that organizes the data into discrete groups (clusters) of the continuous dimension. Grouping using the present methods results in consecutive clusters of continuous dimensions having varying width less than or equal to that of the instrument resolution window. The present methods result in a decreased rate of error relative to the traditional approach.
摘要翻译：提供了用于非目标处理连字色谱数据的方法，使得即使数据表示未知组分的复杂混合物，也会以最少的信息丢失和误差的引入来检测综合数量的组分。通过本方法处理连字色谱数据与使用随后的色谱信息提取算法兼容，并提高随后的峰值/分量拾取程序的精度。本方法包括使用连带色谱技术如GC-MS或LC-MS收集的数据，即具有连续或非离散维度（例如质量）的数据到将数据组织成离散组（簇）的算法连续维度。使用本方法进行分组会导致具有小于或等于仪器分辨率窗口宽度的不同宽度的连续尺寸的连续簇。目前的方法导致了相对于传统方法的误差率。

7. 发明申请

WO2003046798A1 METHODS AND SYSTEMS FOR ANALYZING COMPLEX BIOLOGICAL SYSTEMS 审中-公开
标题翻译：分析复杂生物系统的方法和系统
公开(公告)号：WO2003046798A1
公开(公告)日：2003-06-05
申请号：PCT/US2002/037301
申请日：2002-11-20
申请人： PARADIGM GENETICS, INC. , HAMILTON, Carol , COFFIN, Marie , ALLEN, Keith , LAWRENCE, Matthew , ZHANG, Weiwen , SHUSTER, Jeffrey , DAVIS, Keith , BOYES, Douglas , MULPURI, Rao , TANZER, Matthew , WOESSNER, Jeffrey , HURBAN, Patrick , SLATER, Ted , HOFFMAN, Neil , LIDDELL, Craig , BEECHER, Christopher , GLASSBROOK, Norman , WINFIELD, Stephanie , RANASINGHE, Yasmin , BROADWELL, David , POPA-BURKE, Ioana , NYE, Gordan
发明人： HAMILTON, Carol , COFFIN, Marie , ALLEN, Keith , LAWRENCE, Matthew , ZHANG, Weiwen , SHUSTER, Jeffrey , DAVIS, Keith , BOYES, Douglas , MULPURI, Rao , TANZER, Matthew , WOESSNER, Jeffrey , HURBAN, Patrick , SLATER, Ted , HOFFMAN, Neil , LIDDELL, Craig , BEECHER, Christopher , GLASSBROOK, Norman , WINFIELD, Stephanie , RANASINGHE, Yasmin , BROADWELL, David , POPA-BURKE, Ioana , NYE, Gordan
IPC分类号： G06F19/00
CPC分类号： G06F19/12 , G01N30/72 , G01N30/8655 , G01N30/8658 , G01N30/8662 , G01N30/8679 , G01N30/8693 , G06F19/28 , Y10S707/99943
摘要： The present invention provides methods and systems for organizing complex and disparate data. More specifically, the present invention provides methods and systems for organizing complex and disparate data into coherent data sets. Coherent data sets resulting from the methods and systems of the present invention serve as models for biological systems. Methods and systems for integrating data and creating coherent data sets are useful for numerous biological applications, such as, for example, determining gene function, identifying and validating drug and pesticide targets, identifying and validating drug and pesticide candidate compounds, profiling drug and pesticide compounds, producing a compilation of health or wellness profiles, determining compound site(s) of action, identifying unknown samples, and numerous other applications in the agricultural, pharmaceutical, forensic, and biotechnology industries.
摘要翻译：本发明提供了用于组织复杂且不同的数据的方法和系统。更具体地，本发明提供了将复杂且不同的数据组织成相干数据集的方法和系统。由本发明的方法和系统产生的相干数据集用作生物系统的模型。用于整合数据和创建连贯数据集的方法和系统对于许多生物学应用是有用的，例如确定基因功能，识别和验证药物和农药目标，鉴定和验证药物和农药候选化合物，分析药物和农药化合物编制健康或健康档案汇编，确定复合的行动地点，识别未知样本以及农业，制药，法医和生物技术行业的众多其他应用。

8. 发明申请

WO2008153927A3 GENES AND USES FOR PLANT ENHANCEMENT 审中-公开
标题翻译：用于植物增强的基因和用途
公开(公告)号：WO2008153927A3
公开(公告)日：2009-04-09
申请号：PCT/US2008007105
申请日：2008-06-05
申请人： MONSANTO TECHNOLOGY LLC , COFFIN MARIE
发明人： COFFIN MARIE
IPC分类号： C12N15/87 , A01H5/00 , C12N15/09 , C12N15/82
CPC分类号： C12N15/8261 , C12N15/1079 , Y02A40/146
摘要： Transgenic seed for crops with enhanced agronomic traits are provided by trait- improving recombinant DNA in the nucleus of cells of the seed where plants grown from such transgenic seed exhibit one or more enhanced traits as compared to a control plant. Of particular interest are transgenic plants that have increased yield. The present invention also provides recombinant DNA molecules for expression of a protein, and recombinant DNA molecules for suppression of a protein.
摘要翻译：具有增强的农艺学性状的作物的转基因种子通过在种子细胞的细胞核中改良重组DNA而提供，与对照植物相比，由这种转基因种子生长的植物表现出一种或多种增强的性状。特别感兴趣的是具有增加的产量的转基因植物。本发明还提供了用于表达蛋白质的重组DNA分子和用于抑制蛋白质的重组DNA分子。

9. 发明申请

WO2008070179A3 GENES AND USES FOR PLANT IMPROVEMENT 审中-公开
公开(公告)号：WO2008070179A3
公开(公告)日：2008-11-20
申请号：PCT/US2007025081
申请日：2007-12-06
申请人： MONSANTO TECHNOLOGY LLC , ABAD MARK , CHITTOOR JAISHREE , GOLDMAN BARRY , JOSEPH MITCHELL , RICH RONALD , SHAIKH FATEN , WRAY DIANA , COFFIN MARIE
发明人： ABAD MARK , CHITTOOR JAISHREE , GOLDMAN BARRY , JOSEPH MITCHELL , RICH RONALD , SHAIKH FATEN , WRAY DIANA , COFFIN MARIE
IPC分类号： A01H1/00 , C07H21/04 , C12N5/04 , C12N15/82
CPC分类号： C12N15/8273 , C07K14/415 , C12N15/8241 , C12N15/8247 , C12N15/8251 , C12N15/8261 , C12N15/8271 , C12N15/8274 , C12N15/8275 , C12N15/8282 , C12N15/8283 , C12Q1/6895 , C12Q2600/13 , C12Q2600/158 , G01N33/68 , G01N2333/415
摘要： Transgenic seed for crops with improved traits are provided by trait-improving recombinant DNA in the nucleus of cells of the seed where plants grown from such transgenic seed exhibit one or more improved traits as compared to a control plant. Of particular interest are transgenic plants that have increased yield. The present invention also provides recombinant DNA molecules for expression of a protein, and recombinant DNA molecules for suppression of a protein.

10. 发明申请

WO2009134339A3 GENES AND USES FOR PLANT ENHANCEMENT 审中-公开
公开(公告)号：WO2009134339A3
公开(公告)日：2009-11-05
申请号：PCT/US2009/002547
申请日：2009-04-24
申请人： MONSANTO TECHNOLOGY, LLC , COFFIN, Marie
发明人： COFFIN, Marie
IPC分类号： C12N15/82 , A01H5/00
摘要： Transgenic seed for crops with enhanced agronomic traits are provided by trait- improving recombinant DNA in the nucleus of cells of the seed where plants grown from such transgenic seed exhibit one or more enhanced traits as compared to a control plant. Of particular interest are transgenic plants that have increased yield. The present invention also provides recombinant DNA molecules for expression of a protein, and recombinant DNA molecules for suppression of a protein.

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