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1. 发明申请

WO2008112076A1 RADIOPAQUE POLYMERIC STENT 审中-公开
标题翻译：放射性聚合物
公开(公告)号：WO2008112076A1
公开(公告)日：2008-09-18
申请号：PCT/US2008/002507
申请日：2008-02-26
申请人： BOSTON SCIENTIFIC SCIMED, INC. , HEADLEY, F., Anthony, Jr. , CLERC, Claude , DAMARATI, John , WHITCHER, Forrest, D.
发明人： HEADLEY, F., Anthony, Jr. , CLERC, Claude , DAMARATI, John , WHITCHER, Forrest, D.
IPC分类号： A61F2/06
CPC分类号： A61F2/90 , A61F2/07 , A61F2/885 , A61F2230/0054 , A61F2250/0098 , A61F2310/00395
摘要： The invention relates to an implantable radiopaque stent adapted to be disposed in a body lumen. In one aspect of the invention, at least one radiopaque filament is arranged for permanent attachment to a hollow tubular structure. The filament is desirably arranged in a linear direction traverse to a longitudinal length of the structure, the structure having a tubular wall that defines an inner surface and an outer surface and opposing first open end and second open end. The radiopaque filament improves external imaging of the tubular structure on fluoroscope or x-ray imaging equipment.
摘要翻译：本发明涉及一种可植入的不透射线支架，其适于设置在体腔中。在本发明的一个方面，至少一个不透射线的细丝布置成用于永久地附着到中空管状结构。细丝理想地沿垂直于该结构的纵向长度的线性方向布置，该结构具有限定内表面和外表面以及相对的第一开口端和第二开口端的管状壁。不透射线的灯丝改善了荧光镜或X射线成像设备上的管状结构的外部成像。

2. 发明申请

WO2005110286A9 METHOD FOR REDUCING STENT WELD PROFILES AND A STENT HAVING REDUCED WELD PROFILES AND A CLOSED-END WIRE CONFIGURATION 审中-公开
标题翻译：减少焊接型材的方法和具有减少的焊接型材和闭式端子配置的方法
公开(公告)号：WO2005110286A9
公开(公告)日：2007-01-04
申请号：PCT/US2005016145
申请日：2005-05-10
申请人： BOSTON SCIENT LTD , CLERC CLAUDE O , NORTON PAUL K , ZUPKOFSKA MICHAEL , LEANNE GARY J , ROBERTS GEORGE TOM
发明人： CLERC CLAUDE O , NORTON PAUL K , ZUPKOFSKA MICHAEL , LEANNE GARY J , ROBERTS GEORGE TOM
IPC分类号： A61F2/90 , B23K9/00 , B23K11/00 , B23K15/00 , B23K26/12 , B23K26/20 , B23K37/08 , C23F3/04 , C25F3/16
CPC分类号： A61F2/90 , A61F2220/005 , A61F2220/0058 , A61F2230/001 , A61F2230/0013 , B23H9/02 , B23K9/0026 , B23K11/008 , B23K15/008 , B23K26/12 , B23K26/123 , B23K26/211 , B23K37/08 , B23K2201/06 , B23K2201/22 , B23K2201/32 , C23F3/04 , C25F3/16 , D04C1/06 , D04C3/48 , D10B2403/0112 , D10B2509/06
摘要： A method for making an implantable stent includes the steps of (i) providing a plurality of elongate stent wires; (ii) forming said wires into a hollow tubular structure having opposed first and second open ends; (iii) terminating said wires at the second end; (iv) aligning the wires at the second end into a plurality of mated adjacent wires to define a plurality of abutting regions; (v) welding the mated adjacent wires to one and the other at the abutting regions to define a plurality of welds; and optionally (vi) chemically or electrochemically removing a portion of the welds. The method may further include the steps of (a) extending at least one of the mated stent wires to provide an extended stent wire; (b) looping the extended stent wire so the extended end abuts a proximal pair of stent wires; and (c) welding the extended and looped wire to the proximal pair of wires. The step of looping may include the forming of the wire into an equilaterally arched loop having an apex, but not having other sharp bends.
摘要翻译：一种用于制造可植入支架的方法包括以下步骤：（i）提供多个细长的支架线; （ii）将所述导线形成为具有相对的第一和第二开口端的中空管状结构; （iii）在第二端终止所述电线; （iv）将所述第二端处的所述线对齐成多个配合的相邻线，以限定多个邻接区域; （v）在邻接区域将配合的相邻电线焊接到一个并且另一个以限定多个焊缝; 和（vi）化学或电化学去除一部分焊缝。该方法还可以包括以下步骤：（a）延伸至少一个配合的支架线，以提供延伸的支架线; （b）使扩展的支架线圈环绕，使得延伸端邻接近端的一对支架线; 并且（c）将延伸的和环形的焊丝焊接到近侧的一对电线。循环的步骤可以包括将线形成为具有顶点但没有其它尖锐弯曲的平衡拱形环。

3. 发明申请

WO2002089706A1 METHOD FOR ATTACHING AXIAL FILAMENTS TO A SELF EXPANDING STENT 审中-公开
标题翻译：将轴向光纤连接到自扩展的方法
公开(公告)号：WO2002089706A1
公开(公告)日：2002-11-14
申请号：PCT/US2002/007544
申请日：2002-03-13
申请人： BIONX IMPLANTS, INC. , CLERC, Claude, O. , HOGAN, James, T. , KAUFMANN, Carol, A. , GREENHALGH, E., Skott
发明人： CLERC, Claude, O. , HOGAN, James, T. , KAUFMANN, Carol, A. , GREENHALGH, E., Skott
IPC分类号： A61F2/06
CPC分类号： A61F2/90 , A61F2002/825 , A61F2210/0004 , A61F2250/0048
摘要： Methods for attaching an axial filament (210) to the body of a self expanding stent (200), the filament (210) serving to enhance the radial self expanding force of the stent body (200).
摘要翻译：用于将轴向细丝（210）附接到自扩张支架（200）的主体的方法，所述细丝（210）用于增强支架主体（200）的径向自扩张力。

4. 发明申请

WO2009091899A2 STENT WITH ANTI-MIGRATION FEATURE 审中-公开
标题翻译：具有反移动特征的STENT
公开(公告)号：WO2009091899A2
公开(公告)日：2009-07-23
申请号：PCT/US2009/031119
申请日：2009-01-15
申请人： BOSTON SCIENTIFIC SCIMED, INC. , CLERC, Claude , TUPIL, Sri
发明人： CLERC, Claude , TUPIL, Sri
IPC分类号： A61L31/10 , A61L31/12 , A61L31/14 , A61F2/06
CPC分类号： A61F2/848 , A61F2/07 , A61F2/90 , A61F2002/072 , A61F2002/075 , A61F2002/30322 , A61F2002/8486 , A61F2220/0016 , A61F2230/005 , A61F2230/0078 , A61F2250/0026 , A61F2250/0037 , A61F2250/0039 , A61L31/10 , A61L31/125 , A61L31/14
摘要： An intraluminal prosthesis includes an outer three-dimensional (3D) anti-migration structure that is attached to the outer wall of a fully covered or partially covered stent to prevent migration and still allow stent removal at a later period of time. A method of manufacturing the intraluminal prosthesis includes attaching the anti-migration structure by usage of a polymer such as polyurethane.
摘要翻译：腔内假体包括外部三维（3D）抗迁移结构，其连接到完全覆盖或部分覆盖的支架的外壁上以防止迁移，并且仍允许在稍后时期的支架移除。制造腔内假体的方法包括通过使用诸如聚氨酯的聚合物来附接抗迁移结构。

5. 发明申请

WO2011002641A1 ENDOPROSTHESIS AND ENDOPROSTHESIS DELIVERY SYSTEM AND METHOD 审中-公开
标题翻译：内源性和内源性递送系统及方法
公开(公告)号：WO2011002641A1
公开(公告)日：2011-01-06
申请号：PCT/US2010/039572
申请日：2010-06-23
申请人： BOSTON SCIENTIFIC SCIMED, INC. , CLERC, Claude, O. , KILGANNON, Martin, Patrick
发明人： CLERC, Claude, O. , KILGANNON, Martin, Patrick
IPC分类号： A61F2/84
CPC分类号： A61F2/95 , A61F2002/9505 , A61F2002/9511
摘要： An endoprosthesis includes a structure which is self-expandable from a reduced profile to an expanded profile. The structure has one or more longitudinal portions and a transverse central plane about which the one or more longitudinal portions are symmetric. A removable sheath retains the one or more longitudinal portions in the reduced profile. A release structure is coupled to the sheath for removal thereof from the one or more longitudinal portions to provide the self-expansion thereof to the expanded profile. A method for implanting the endoprosthesis into a body of a patient includes inserting the structure which is covered by the sheath into the body of the patient such that the structure has the reduced profile. The release structure is then actuated for removing the sheath from the one or more longitudinal portions to provide the self-expansion to the expanded profile.
摘要翻译：内假体包括从减小的轮廓到扩张的轮廓自展开的结构。该结构具有一个或多个纵向部分和横向中心平面，一个或多个纵向部分围绕该中心平面对称。可移除的护套将一个或多个纵向部分保持在缩小的轮廓中。释放结构联接到护套上，用于将其从一个或多个纵向部分移除以提供其扩展到膨胀型材。用于将内假体植入患者体内的方法包括将由护套覆盖的结构插入患者的身体，使得结构具有减小的轮廓。然后致动释放结构以从一个或多个纵向部分移除护套以向膨胀型材提供自膨胀。

6. 发明申请

WO2009091899A3 STENT WITH ANTI-MIGRATION FEATURE 审中-公开
标题翻译：具有反移动特征的STENT
公开(公告)号：WO2009091899A3
公开(公告)日：2010-06-17
申请号：PCT/US2009031119
申请日：2009-01-15
申请人： BOSTON SCIENT SCIMED INC , CLERC CLAUDE , TUPIL SRI
发明人： CLERC CLAUDE , TUPIL SRI
IPC分类号： A61L31/10 , A61F2/90 , A61L31/12 , A61L31/14
CPC分类号： A61F2/848 , A61F2/07 , A61F2/90 , A61F2002/072 , A61F2002/075 , A61F2002/30322 , A61F2002/8486 , A61F2220/0016 , A61F2230/005 , A61F2230/0078 , A61F2250/0026 , A61F2250/0037 , A61F2250/0039 , A61L31/10 , A61L31/125 , A61L31/14
摘要： An intraluminal prosthesis includes an outer three-dimensional (3D) anti-migration structure that is attached to the outer wall of a fully covered or partially covered stent to prevent migration and still allow stent removal at a later period of time. A method of manufacturing the intraluminal prosthesis includes attaching the anti-migration structure by usage of a polymer such as polyurethane.
摘要翻译：腔内假体包括外部三维（3D）抗迁移结构，其连接到完全覆盖或部分覆盖的支架的外壁上以防止迁移，并且仍允许在稍后时期的支架移除。制造腔内假体的方法包括通过使用诸如聚氨酯的聚合物来附接抗迁移结构。

7. 发明申请

WO2010025102A1 ENDOSCOPIC SUTURING DEVICE 审中-公开
标题翻译：内窥镜装置
公开(公告)号：WO2010025102A1
公开(公告)日：2010-03-04
申请号：PCT/US2009/054736
申请日：2009-08-24
申请人： BOSTON SCIENTIFIC SCIMED, INC. , CLERC, Claude , RIOUX, Robert, F.
发明人： CLERC, Claude , RIOUX, Robert, F.
IPC分类号： A61B17/04
CPC分类号： A61B17/0469 , A61B17/0482 , A61B90/361 , A61B2017/00296 , A61B2017/047 , A61B2017/0472 , A61B2017/22069 , A61B2017/2905 , A61B2017/2927 , A61B2017/2931
摘要： A suturing device (100) for use in endoscopic procedures includes a head (120) configured to be removably coupled to an elongate medical device (110) and an actuator (150) coupled to the head (120) via an elongate flexible sheath (130). The suturing device is configured to pass a needle and suture through a selected tissue site upon actuation of the actuator. In another embodiment, a suturing device (400) includes a head (420) and a retaining portion (461) configured to receive a guide wire. The suturing device can be inserted into a patient's body using the guide wire (490) to guide and help position the head (420) of the suturing device. In such an embodiment, the suturing device can also include an expandable (670) member coupled to the head and that is configured to be expanded within a body lumen of a patient to help maintain a position of the head within the body lumen.
摘要翻译：用于内窥镜手术的缝合装置（100）包括头部（120），其构造成可移除地联接到细长医疗装置（110），以及通过细长的柔性护套（130）联接到头部（120）的致动器（150））。缝合装置构造成在致动器致动时将针和缝合线穿过选定的组织部位。在另一个实施例中，缝合装置（400）包括头部（420）和构造成接收导丝的保持部分（461）。缝合装置可以使用导丝（490）插入患者体内，以引导和帮助定位缝合装置的头部（420）。在这样的实施例中，缝合装置还可以包括联接到头部的可膨胀（670）构件，并且构造成在患者的体腔内扩张，以帮助保持头部在体腔内的位置。

8. 发明申请

WO2007047151A1 BRONCHOSCOPIC LUNG VOLUME REDUCTION VALVE 审中-公开
标题翻译： BRONCHOSCOPIC LUNG减压阀
公开(公告)号：WO2007047151A1
公开(公告)日：2007-04-26
申请号：PCT/US2006/039070
申请日：2006-10-04
申请人： BOSTON SCIENTIFIC SCIMED, INC. , CLERC, Claude
发明人： CLERC, Claude
IPC分类号： A61F2/24
CPC分类号： A61F2/04 , A61B17/12022 , A61B17/12104 , A61B17/12172 , A61B2017/00575 , A61B2017/00592 , A61B2017/00597 , A61B2017/00606 , A61B2017/00615 , A61B2017/00619 , A61F2/07 , A61F2/24 , A61F2/82 , A61F2/90 , A61F2002/043 , A61F2210/0014 , A61F2210/0057 , A61F2220/0008 , A61F2230/0078 , A61F2230/008 , A61F2250/001 , A61F2250/0039 , A61M39/22 , A61M2039/244 , A61M2039/248 , A61M2210/1039 , F16K15/00 , F16K99/0003 , F16K2099/0088
摘要： A valve (100) to perform lung volume reduction procedures is described. The valve is formed of a braided structure that is adapted for endoscopic insertion in a bronchial passage of a patient's lung. The braided structure (102) has a proximal end (104) and a distal end (106) and is covered with a non porous coating (112) adapted to prevent flow of air into the lung. A constricted portion of the braided structure is used to prevent flow of air through a central lumen of the structure, and to define at least one funnel shaped portion. The funnel shaped portion blocks the flow of air towards the constriction, i.e. towards the core of the lung. At least one hole (110) is formed in the braided structure to permit flow of mucus from the distal end to the proximal end, to be expelled out of the lungs.
摘要翻译：描述了执行肺容积减小过程的瓣膜（100）。阀由编织结构形成，其适于内窥镜插入患者肺的支气管通道中。编织结构（102）具有近端（104）和远端（106），并且覆盖有适于防止空气流入肺的非多孔涂层（112）。编织结构的收缩部分用于防止空气流过结构的中心腔，并且限定至少一个漏斗形部分。漏斗形部分阻止朝向收缩部的空气流，即朝向肺的核心。在编织结构中形成至少一个孔（110），以允许粘液从远端流到近端，以便从肺排出。

9. 发明申请

WO2006053270A3 ATRAUMATIC STENT WITH REDUCED DEPLOYMENT FORCE, METHOD FOR MAKING THE SAME AND METHOD AND APPARATUS FOR DEPLOYING AND POSITIONING THE STENT 审中-公开
标题翻译：具有减小部署力的ATRAUMATIC STENT，制造该部件的方法以及用于部署和定位该STENT的方法和设备
公开(公告)号：WO2006053270A3
公开(公告)日：2006-08-24
申请号：PCT/US2005041083
申请日：2005-11-10
申请人： BOSTON SCIENT SCIMED INC , NORTON PAUL , ZUPKOFSKA MICHAEL , BRADY PETER , LEANNA GARY J , CLERC CLAUDE O , BERTOLINO WILLIAM , HANLEY GRAINNE
发明人： NORTON PAUL , ZUPKOFSKA MICHAEL , BRADY PETER , LEANNA GARY J , CLERC CLAUDE O , BERTOLINO WILLIAM , HANLEY GRAINNE
IPC分类号： A61F2/90
CPC分类号： A61F2/90 , A61F2220/0058 , A61F2250/0039 , A61F2250/0098 , D04C1/06 , D10B2509/06
摘要： An implantable stent (10, 10') includes a plurality of elongate wires (18) braided to form a hollow tubular structure having a tubular wall (16) to define an interior surface (106) and an,exterior surface (104) and having opposed open first and second ends (12.14), wherein the opposed open first and second ends (12, 14) are atraumatic ends The atraumatic ends of the stent are desirably free of any loose wire ends. The wires (18) include composite wires to enhance visibility of the wires to provide improved external imaging of the wires in the body. The elongate composite wires of the stent may be metallic wires having an outer metallic portion including a first metal, such as nitinol, and an inner metallic core portion including a second metal, which is a radiopaque material, such as gold, barium sulfate, ferritic particles, platinum, platinum-tungsten, palladium, platinum-iridium, rhodium, tantalum or combinations thereof.
摘要翻译：一种植入式支架（10,10'）包括多根编织成中空管状结构的细长丝（18），所述中空管状结构具有管状壁（16）以限定内表面（106）和外表面（104），并且具有相对的敞开的第一和第二端部（12.14），其中相对的敞开的第一和第二端部（12,14）是防创伤端部。支架的防损伤端部理想地没有任何松散的线端部。导线（18）包括复合导线以增强导线的可见性，从而改善体内导线的外部成像。支架的细长复合金属丝可以是金属丝，其具有包含第一金属（例如镍钛诺）的外金属部分和包含第二金属的内金属芯部分，所述第二金属是不透射线材料，诸如金，硫酸钡，铁素体颗粒，铂，铂 - 钨，钯，铂 - 铱，铑，钽或其组合。

10. 发明申请

WO2006081448A1 STENT RETRIEVAL MEMBER AND DEVICES AND METHODS FOR RETRIEVING OR REPOSITIONING A STENT 审中-公开
标题翻译： STENT RETRIEVAL MEMBER AND DEVICES AND METHODS FOR RETRIEVING or REPOSITIONING STET
公开(公告)号：WO2006081448A1
公开(公告)日：2006-08-03
申请号：PCT/US2006/002984
申请日：2006-01-27
申请人： BOSTON SCIENTIFIC SCIMED, INC. , JORDAN, Gary, A. , CLERC, Claude, O. , NORTON, Paul, K. , ZUPKOFSKA, Michael , DAMARATI, John, J.
发明人： JORDAN, Gary, A. , CLERC, Claude, O. , NORTON, Paul, K. , ZUPKOFSKA, Michael , DAMARATI, John, J.
IPC分类号： A61F2/06
CPC分类号： A61F2/90 , A61F2/885 , A61F2/95 , A61F2002/9511 , A61F2002/9528 , A61F2002/9534 , A61F2210/0014 , A61F2210/0057 , A61F2230/0069 , A61F2250/0039
摘要： An implantable stent includes a stent retrieval member (30) for repositioning or retrieval of the stent after it has been implanted into a bodily lumen. The stent includes a distensible tubular stent (10) having a tubular structure having a tubular wall (16) defined by an interior surface and an exterior surface and having opposed open ends (12,14) ; and a stent retrieval member (30) comprising an elongate member comprising a generally circular perimetric base (32) and a shaped projection (34) having first and second spaced apart members (36,38) extending acutely or perpendicularly from the base (32) and connected by an apical portion (40) . Force exerted on the shaped projection causes contraction or expansion of the circular base. The circular base is securably attached to one of the open ends of the stent, and the shaped projection extends longitudinally beyond this open end of the stent.
摘要翻译：可植入支架包括支架取回构件（30），用于在将支架植入体腔后重新定位或取回支架。支架包括具有管状结构的可扩张的管状支架（10），该管状结构具有由内表面和外表面限定并具有相对的开放端（12,14）的管状壁（16）。以及支架回收构件（30），其包括细长构件，所述细长构件包括大致圆形的周边基部（32）和具有从所述基部（32）突出或垂直延伸的第一和第二间隔开的构件（36,38）的成形突起（34）并通过顶部部分（40）连接。施加在成形突起上的力导致圆形底部的收缩或膨胀。圆形基座牢固地连接到支架的一个开口端，并且成形突出部纵向地延伸超出支架的该开口端。

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