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1. 发明申请

WO1996002663A1 PROCESS FOR PREPARATION OF 'beta'-LACTAMS AT CONSTANTLY HIGH CONCENTRATION OF REACTANTS 审中-公开
标题翻译：制备抗体强度高的β-L-胆固醇的方法
公开(公告)号：WO1996002663A1
公开(公告)日：1996-02-01
申请号：PCT/EP1995002876
申请日：1995-07-18
申请人： GIST-BROCADES B.V. , CLAUSEN, Kim , DEKKERS, Rocus, Marinus
发明人： GIST-BROCADES B.V.
IPC分类号： C12P37/04
CPC分类号： C12P35/04 , C12P37/04
摘要： beta -Lactam derivatives can advantageously by synthesized by an enzymatic reaction of the parent amino beta -lactam with the corresponding acylating agent at constantly high concentrations of said reactants.
摘要翻译： β-内酰胺衍生物可以有利地通过母体氨基β-内酰胺与相应的酰化剂在不断高浓度的所述反应物的酶反应合成。

2. 发明申请

WO2007082544A1 A NOVEL DRY STICK DEVICE CONSTRUCTION AND METHOD FOR DETERMINING AN ANALYTE IN A SAMPLE USING SAID DRY STICK DEVICE 审中-公开
标题翻译：一种新型干燥装置结构和方法，用于使用干燥的干燥装置确定样品中的分析物
公开(公告)号：WO2007082544A1
公开(公告)日：2007-07-26
申请号：PCT/DK2007/050004
申请日：2007-01-19
申请人： Lattec I/S , CLAUSEN, Kim
发明人： CLAUSEN, Kim
IPC分类号： G01N33/52 , G01N33/558
CPC分类号： C12Q1/32 , G01N33/521 , G01N33/54386 , Y10T156/10
摘要： A novel dry stick device construction for the determination of an analyte in a sample is provided. The device comprises: (i) optionally a solid support, (ii) at least one reagent pad comprising a reagent or a combination of reagents capable of reacting with the analyte, a derivative of said analyte or an indicator compound for said analyte to provide a detectable signal when in a moistened state, the at least one reagent pad providing a first environment for said reagent(s), said first environment permitting an improved storage stability of the reagent(s) and dry stick device when in a non-moistened state, and (iii) a regulating pad being in contact with the at least one reagent pad, the regulating pad creating a second environment for said reagent(s), when in a moistened state, said second environment permitting an increased rate of reaction between the analyte and the reagent.
摘要翻译：提供了一种用于测定样品中分析物的新型干棒装置结构。该装置包括：（i）任选的固体支持物，（ii）至少一个试剂垫，其包含能够与分析物反应的试剂或试剂的组合，所述分析物的衍生物或所述分析物的指示剂化合物，以提供当处于润湿状态时，所述至少一个试剂垫为所述试剂提供第一环境，所述第一环境允许当处于非润湿状态时试剂和干棒装置的储存稳定性得到改善，和（iii）与所述至少一个试剂垫接触的调节垫，所述调节垫在所述试剂的第二环境中产生第二环境，当处于润湿状态时，所述第二环境允许所述第二环境中的反应速率增加分析物和试剂。

3. 发明申请

WO1993023164A1 SEPARATION METHOD 审中-公开
标题翻译：分离方法
公开(公告)号：WO1993023164A1
公开(公告)日：1993-11-25
申请号：PCT/DK1993000159
申请日：1993-05-13
申请人： NOVO NORDISK A/S , KAASGAARD, Svend, Gunnar , ULRICH, Camilla, Helene , CLAUSEN, Kim , JENSEN, Thomas, Lisbjerg
发明人： NOVO NORDISK A/S
IPC分类号： B01J37/02
CPC分类号： B01J38/00 , B01J37/009
摘要： The present invention relates to a method of separating a particulate solid catalyst from a chemical reaction mixture which further comprises at least one other solid component, either during the reaction or after the reaction.
摘要翻译：本发明涉及一种从化学反应混合物中分离颗粒状固体催化剂的方法，该反应混合物在反应期间或反应后还包含至少一种其它固体组分。

4. 发明申请

WO1989001525A1 PROCESS FOR PREPARATION OF ORGANIC CHEMICALS 审中-公开
标题翻译：有机化学品的制备方法
公开(公告)号：WO1989001525A1
公开(公告)日：1989-02-23
申请号：PCT/DK1988000134
申请日：1988-08-17
申请人： NOVO INDUSTRI A/S , STAMICARBON, B.V. , GODTFREDSEN, Sven, Erik , CLAUSEN, Kim , INGVORSEN, Kjeld , HERMES, Hubertus, Fransiscus, Maria , VAN BALKEN, Johannes, Arnoldus, Maria , MEIJER, Emmo, Marinus
发明人： NOVO INDUSTRI A/S , STAMICARBON, B.V.
IPC分类号： C12P13/02
CPC分类号： C12P41/006 , C12P13/02 , C12P17/10
摘要： Process for the racemization of an amino acid amide with general formula (I), the amino acid amide being brought into contact with an enzyme with amino acid amide racemase activity. In particular the invention relates to a process for enzymatic preparation of optically active amino acids from amino acid amides by bringing the amino acid amide into contact with a biocatalyst which in addition possesses L- or D-amidase activity.
摘要翻译：用通式（I）的氨基酰胺外消旋化的方法，使氨基酰胺与具有氨基酰胺酰胺消旋酶活性的酶接触。特别地，本发明涉及通过使氨基酰胺与另外具有L-或D-酰胺酶活性的生物催化剂接触从氨基酰胺酶制备光学活性氨基酸的方法。

5. 发明申请

WO2009095121A1 PLANT FOR MANUFACTURING CEMENT 审中-公开
标题翻译：制造水泥厂
公开(公告)号：WO2009095121A1
公开(公告)日：2009-08-06
申请号：PCT/EP2008/066005
申请日：2008-11-21
申请人： FLSMIDTH A/S , ROSHOLM, Peter , CLAUSEN, Kim
发明人： ROSHOLM, Peter , CLAUSEN, Kim
IPC分类号： F27B7/20 , C04B7/60 , C04B7/44 , C04B7/43 , B01D53/00
CPC分类号： F27B7/20 , B01D7/02 , B01D53/002 , B01D2257/2045 , B01D2257/708 , C04B7/436 , C04B7/4492 , C04B7/60 , F27D17/008 , Y02P40/121
摘要： Described is a plant for manufacturing cement, which plant comprises a cyclone preheater (1) for preheating cement raw materials, a calciner (3) for calcination of preheated cement raw materials, a kiln (5) for burning cement clinker, as well as means (12) for removing volatile components, such as chloride, alkali and sulphur, from the cement manufacturing plant. The plant is peculiar in that at least some of the means (12) for removing volatile components from the plant are located after the calciner (3) viewed in the direction of movement of the gases. It is hereby obtained, that significant amounts of volatile components, such as chloride, particularly KCI, may be removed from the plant since the removal is effected at the location of the plant where the highest concentration of these components occur, thereby avoiding coatings and clogging further upstream in the preheater. Also, the energy loss will be reduced since the gases after the calciner have a temperature which is lower than that occurring immediately after the kiln, and, therefore, there the volatile components need not to be cooled to the same extent in order to achieve condensation. Another advantage of the plant according to the invention is that the draught conditions and the mixing ratio of the gases which are drawn through the calciner and the preheater will be far less disrupted.
摘要翻译：描述了一种用于制造水泥的设备，该设备包括用于预热水泥原料的旋风预热器（1），用于煅烧预热水泥原料的煅烧炉（3），用于燃烧水泥熟料的窑炉（5）（12）从水泥制造厂去除挥发性成分，如氯化物，碱和硫。该设备是特别的，因为用于从植物中去除挥发性组分的至少一些装置（12）位于从气体运动方向观察的煅烧炉（3）之后。因此，在这些组分发生最高浓度的工厂的位置进行除去，可以从植物中除去大量挥发性成分，如氯化物，特别是氯化钾，从而避免涂层和堵塞进一步在预热器的上游。此外，由于煅烧炉后的气体的温度低于窑后立即产生的温度，因此能量损失将会降低，因此，挥发性组分不需要冷却至相同程度以达到冷凝。根据本发明的设备的另一个优点是通过煅烧炉和预热器吸入的气体的通风条件和混合比将被破坏得很少。

6. 发明申请

WO1995034675A1 IMPROVED ACYLATION METHOD FOR PENICILLINS AND CEPHALOSPORINS 审中-公开
标题翻译：改良的泼尼松和醋酸蛋白酶的方法
公开(公告)号：WO1995034675A1
公开(公告)日：1995-12-21
申请号：PCT/EP1995002277
申请日：1995-06-12
申请人： GIST-BROCADES B.V. , CLAUSEN, Kim , NIELSEN, Annette , PETERSEN, Niels , NIKOLOV, Alexander
发明人： GIST-BROCADES B.V.
IPC分类号： C12P35/04
CPC分类号： C12P37/04 , C12P35/04
摘要： The present invention provides an improved method for enzymatic acylation to prepare semisynthetic beta -lactam antibiotics by the application of modulators to suppress the hydrolysis of the acylating agent more than the synthesis of the desired product.
摘要翻译：本发明提供了一种改进的酶促酰化方法，通过应用调节剂来制备半合成β-内酰胺抗生素，以抑制酰化剂的水解比所需产物的合成更多。

7. 发明申请

WO1993012250A1 AN IMPROVED METHOD FOR THE PREPARATION OF CERTAIN 'beta'-LACTAM ANTIBIOTICS 审中-公开
标题翻译：一种用于制备某些β--LACTAM抗生素的改进方法
公开(公告)号：WO1993012250A1
公开(公告)日：1993-06-24
申请号：PCT/DK1992000388
申请日：1992-12-18
申请人： NOVO NORDISK A/S , CLAUSEN, Kim
发明人： NOVO NORDISK A/S
IPC分类号： C12P37/04
CPC分类号： C12P35/04
摘要： The present invention relates to an improved method for the preparation of certain beta -lactam antibiotics by enzymatic acylation or by deprotection of a protected intermediate.
摘要翻译：本发明涉及通过酶促酰化或通过保护的中间体的脱保护来制备某些β-内酰胺抗生素的改进方法。

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