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1. 发明申请

WO2011132901A2 NOVEL BENZAMIDE DERIVATIVES 审中-公开
标题翻译：新的苯甲酸衍生物
公开(公告)号：WO2011132901A2
公开(公告)日：2011-10-27
申请号：PCT/KR2011/002759
申请日：2011-04-18
申请人： DONG-A PHARM.CO., LTD. , KIM, Soon-Hoe , IM, Weon-Bin , CHOI, Sung-Hak , CHOI, Sun-Ho , SOHN, Ju-Hee , SUNG, Hyun-Jung , KIM, Mi-Yeon , CHO, Kang-Hun , SOHN, Tae-Kyoung
发明人： KIM, Soon-Hoe , IM, Weon-Bin , CHOI, Sung-Hak , CHOI, Sun-Ho , SOHN, Ju-Hee , SUNG, Hyun-Jung , KIM, Mi-Yeon , CHO, Kang-Hun , SOHN, Tae-Kyoung
IPC分类号： C07D211/16 , C07D211/26 , A61K31/435
CPC分类号： C07D401/06 , C07D211/26
摘要： The present invention provides a novel benzamide derivative or a pharmaceutically acceptable salt thereof, a method for preparing the same, and a 5-HT 4 receptor agonist containing the same as an active ingredient. Benzamide derivatives of the present invention have a superior affinity for 5-HT 4 receptors, a capability to reduce a gastric emptying time and a low toxicity, and consequently are therapeutically effective for the treatment of a variety of diseases associated with 5-HT 4 receptors.
摘要翻译：本发明提供了一种新的苯甲酰胺衍生物或其药学上可接受的盐，其制备方法和含有该活性成分的5-HT 4受体激动剂。本发明的苯甲酰胺衍生物对5-HT 4受体具有优异的亲和力，降低胃排空时间和低毒性的能力，因此对于治疗与5-HT 4受体相关的各种疾病具有治疗上的有效性。

2. 发明申请

WO2008114971A1 NOVEL BENZAMIDE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF 审中-公开
标题翻译：新型苯并噻吩衍生物及其制备方法
公开(公告)号：WO2008114971A1
公开(公告)日：2008-09-25
申请号：PCT/KR2008/001465
申请日：2008-03-14
申请人： DONG-A PHARM. CO., LTD. , YOO, Moo-Hi , RHEE, Jae-Keol , IM, Weon-Bin , CHOI, Sung-Hak , KIM, Eun-Jung , PARK, Jung-Sang , CHOI, Sun-Ho , SHON, Tae-Kyoung , SUNG, Hyun-Jung , KIM, Ja-Young , SHON, Ju-Hee
发明人： YOO, Moo-Hi , RHEE, Jae-Keol , IM, Weon-Bin , CHOI, Sung-Hak , KIM, Eun-Jung , PARK, Jung-Sang , CHOI, Sun-Ho , SHON, Tae-Kyoung , SUNG, Hyun-Jung , KIM, Ja-Young , SHON, Ju-Hee
IPC分类号： C07D211/62 , C07D401/06 , C07D401/12 , C07D417/12 , A61K31/165 , A61K31/445 , A61P1/00 , A61P1/06
CPC分类号： C07D401/12 , C07D211/58 , C07D401/06 , C07D405/06 , C07D413/06 , C07D417/12
摘要： The present invention provides a novel benzamide derivative represented by formula 1 and an isomer, a pharmaceutically acceptable salt or hydrate thereof, and a composition for activating a 5-HT 4 receptor comprising the same, as an active ingredient. Benzamide derivatives of the present invention has superior affinity for 5-HT 4 receptors, capability to reduce the gastric evacuation time, capability to alleviate ventricular tachycardia, ventricular fibrillation, torsades de pointes and QT prolongation, and low toxicity. Therefore, benzamide derivatives of the present invention are therapeutically effective for digestive system diseases.
摘要翻译：本发明提供一种由式1表示的新型苯甲酰胺衍生物及其异构体，药学上可接受的盐或水合物，以及用于活化含有该化合物的5-HT 4受体作为活性成分的组合物。本发明的苯甲酰胺衍生物对5-HT 4受体具有优异的亲和力，降低胃抽空时间，减轻室性心动过速，心室颤动，尖端扭转型室间隔和QT延长的能力以及低毒性。因此，本发明的苯甲酰胺衍生物对于消化系统疾病是治疗有效的。

3. 发明申请

WO2005058886A1 NOVEL OXAZOLIDINONE DERIVATIVES 审中-公开
标题翻译：新型氧杂环丁酮衍生物
公开(公告)号：WO2005058886A1
公开(公告)日：2005-06-30
申请号：PCT/KR2004/003327
申请日：2004-12-17
申请人： DONG-A PHARM.CO.,LTD. , RHEE, Jae Keol , IM, Weon Bin , CHO, Chong Hwang , CHOI, Sung Hak , LEE, Tae Ho
发明人： RHEE, Jae Keol , IM, Weon Bin , CHO, Chong Hwang , CHOI, Sung Hak , LEE, Tae Ho
IPC分类号： C07D413/14
CPC分类号： A61K31/4439 , A61K31/675 , C07D263/32 , C07D413/14 , C07D417/10 , C07D417/14 , C07F9/653 , C07F9/65583
摘要： The present invention relates to novel derivatives of oxazolidinone, a method thereof and pharmaceutical compositions comprising the derivatives for use in an antibiotic. The oxazolidinone derivatives of the present invention show inhibitory activity against a broad spectrum of bacteria and lower toxicity. The prodrugs, prepared by reacting the compound having hydroxyl group with amino acid or phosphate, have an excellent efficiency on solubility thereof against water. Further, the derivatives of the present invention may exert potent antibacterial activity versus various human and animal pathogens, including Gram-positive bacteria such as Staphylococi, Enterococci and Streptococi, anaerobic microorganisms such as Bacteroides and Clostridia, and acid-resistant microorganisms such as Mycobacterium tuberculosis and Mycobacterium avium. Accordingly, the compositions comprising the oxazolidinone are used in an antibiotic.
摘要翻译：本发明涉及恶唑烷酮的新衍生物，其方法和药物组合物，其包含用于抗生素的衍生物。本发明的恶唑烷酮衍生物显示出对广谱细菌的抑制活性和较低的毒性。通过使具有羟基的化合物与氨基酸或磷酸酯反应制备的前药在对水的溶解性方面具有优异的效果。此外，本发明的衍生物可以相对于各种人和动物病原体，包括葡萄球菌，肠球菌和链球菌等革兰阳性菌，拟杆菌和梭菌等厌氧菌，耐结核菌如结核分枝杆菌和鸟分枝杆菌。因此，包含恶唑烷酮的组合物用于抗生素中。

4. 发明申请

WO2011132901A3 NOVEL BENZAMIDE DERIVATIVES 审中-公开
标题翻译：新的苯甲酸衍生物
公开(公告)号：WO2011132901A3
公开(公告)日：2012-01-26
申请号：PCT/KR2011002759
申请日：2011-04-18
申请人： DONG A PHARM CO LTD , KIM SOON-HOE , IM WEON-BIN , CHOI SUNG-HAK , CHOI SUN-HO , SOHN JU-HEE , SUNG HYUN-JUNG , KIM MI-YEON , CHO KANG-HUN , SOHN TAE-KYOUNG
发明人： KIM SOON-HOE , IM WEON-BIN , CHOI SUNG-HAK , CHOI SUN-HO , SOHN JU-HEE , SUNG HYUN-JUNG , KIM MI-YEON , CHO KANG-HUN , SOHN TAE-KYOUNG
IPC分类号： C07D211/16 , A61K31/435 , C07D211/26
CPC分类号： C07D401/06 , C07D211/26
摘要： The present invention provides a novel benzamide derivative or a pharmaceutically acceptable salt thereof, a method for preparing the same, and a 5-HT4 receptor agonist containing the same as an active ingredient. Benzamide derivatives of the present invention have a superior affinity for 5-HT4 receptors, a capability to reduce a gastric emptying time and a low toxicity, and consequently are therapeutically effective for the treatment of a variety of diseases associated with 5-HT4 receptors.
摘要翻译：本发明提供了一种新的苯甲酰胺衍生物或其药学上可接受的盐，其制备方法和含有该活性成分的5-HT 4受体激动剂。本发明的苯甲酰胺衍生物对5-HT 4受体具有优异的亲和力，降低胃排空时间和低毒性的能力，因此对于治疗与5-HT 4受体相关的各种疾病具有治疗上的有效性。

5. 发明申请

WO2009022832A1 AN APPARATUS FOR CLEANING A MEMBRANE MODULE AND A METHOD THEREFOR. 审中-公开
标题翻译：用于清洁膜模块的装置及其方法。
公开(公告)号：WO2009022832A1
公开(公告)日：2009-02-19
申请号：PCT/KR2008/004656
申请日：2008-08-11
申请人： KOLON INDUSTRIES, INC. , LEE, Kwang-Jin , CHOI, Sung-Hak , LEE, Moo-Seok
发明人： LEE, Kwang-Jin , CHOI, Sung-Hak , LEE, Moo-Seok
IPC分类号： B01D65/08
CPC分类号： B01D65/025 , B01D2321/02 , B01D2321/16
摘要： Disclosed are an apparatus for cleaning a membrane module and a method therefor, which can minimize consumption of chemicals required to clean the membrane module while maximizing a recovery cleaning rate of the membrane module without completely stopping a water treatment operation. The cleaning apparatus includes a first flushing bath for flushing a membrane module transferred from a water treatment tank, and a first chemical cleaning bath for cleaning the membrane module, which has been completely flushed and transferred from the first flushing bath, by use of a first chemical solution.
摘要翻译：公开了一种用于清洁膜组件的设备及其方法，其可以最大限度地提高膜组件的回收清洁率而不会完全停止水处理操作，从而最小化清洁膜组件所需的化学品的消耗。清洗装置包括用于冲洗从水处理槽传送的膜组件的第一冲洗槽和用于清洗已经被完全冲洗并从第一冲洗槽传送的膜组件的第一化学清洗槽，化学溶液。

6. 发明申请

WO2008133430A1 SUBMERGED TYPE HOLLOW FIBER MEMBRANE MODULE 审中-公开
标题翻译：中空型中空纤维膜模块
公开(公告)号：WO2008133430A1
公开(公告)日：2008-11-06
申请号：PCT/KR2008/002284
申请日：2008-04-23
申请人： KOLON INDUSTRIES, INC. , LEE, Moo-Seok , CHOI, Sung-Hak
发明人： LEE, Moo-Seok , CHOI, Sung-Hak
IPC分类号： B01D69/08
CPC分类号： B01D63/022 , B01D63/023 , B01D63/024 , B01D2315/06 , Y10T156/10
摘要： A submerged-type hollow fiber membrane module and a method for manufacturing the same is disclosed, which is capable of realizing a great sealing strength between a module case and a bundle of hollow fiber membranes without an additional centrifugal molding apparatus, the method comprising forming a bundle of hollow fiber membranes held together and fixed by a first potting material, wherein one end of each of the hollow fiber membranes is open; putting the bundle of hollow fiber membranes in a module case and fixing the bundle of hollow fiber membranes in the module case by forming a second potting material on the first potting material.
摘要翻译：公开了一种浸没式中空纤维膜组件及其制造方法，其能够在没有另外的离心成型装置的情况下实现模块壳体与一束中空纤维膜之间的极好的密封强度，该方法包括：一束中空纤维膜保持在一起并由第一灌封材料固定，其中每个中空纤维膜的一端是开放的; 将一束中空纤维膜放入模块外壳中，并在第一灌封材料上形成第二灌封材料将中空纤维膜束固定在模块外壳中。

7. 发明申请

WO2003017600A1 AN APPARATUS CONNECTED MULTI IP BROADBAND LINE AND FALLBACK METHOD THEREOF 审中-公开
标题翻译：一种装置连接的多路IP宽带线及其倒带方法
公开(公告)号：WO2003017600A1
公开(公告)日：2003-02-27
申请号：PCT/KR2002/001550
申请日：2002-08-14
申请人： SMALLBIG TECHNOLOGY INC. , CHOI, Sung-hak , KIM, Jung-hoon , CHO, Gug-yong
发明人： CHOI, Sung-hak , KIM, Jung-hoon , CHO, Gug-yong
IPC分类号： H04L12/66
CPC分类号： H04L12/5692 , H04L12/2801 , H04L69/16 , H04L69/165 , H04L69/40
摘要： This invention aims to provide an apparatus supporting a plurality of broadband communication lines and fallback routing method thereof which supports Internet access with no disconnection while disconnecting and switching to one communication line available among a plurality of communication lines according to line condition. This present invention in order to achieve said purpose enables functions such as connecting user computer to one primary communication line among a plurality of communication lines, implementing periodical ping test to said every communication line, and disconnecting the connection between said user computer and said primary communication line when the response of primary communication line gets downed, or slower than the criteria according to the result of ping test, connecting one backup communication line of remaining communication lines except said primary line which have Internet accessibility to said user computer, implementing periodical ping test to said every communication line, and disconnecting said user computer with . backup communication line, when the ping test of primary communication line recovers it's normal state, connecting said primary communication line to said user computer agam.
摘要翻译：本发明的目的在于提供一种支持多条宽带通信线路的设备及其回退路由方法，该方法在根据线路条件断开并切换到多条通信线路中的一条通信线路的同时，不断开，支持因特网接入。为了实现上述目的，本发明实现了将用户计算机连接到多条通信线路中的一条主通信线路的功能，对所述每条通信线路实施定期ping测试，并且断开所述用户计算机与所述主要通信之间的连接当主通信线路的响应降低或比根据ping测试结果的标准慢时，将除了具有因特网可访问性的主线路之外的剩余通信线路的一条备用通信线路连接到所述用户计算机，实现定期ping测试说每个通信线路，并断开所述用户计算机。备用通信线路，当主通信线路的ping测试恢复正常状态时，将所述主通信线路连接到所述用户计算机接口。

8. 发明申请

WO2008097011A1 A TUBULAR BRAID AND COMPOSITE HOLLOW FIBER MEMBRANE USING THE SAME 审中-公开
标题翻译：使用相同的管状布和复合中空纤维膜
公开(公告)号：WO2008097011A1
公开(公告)日：2008-08-14
申请号：PCT/KR2008/000703
申请日：2008-02-05
申请人： KOLON INDUSTRIES, INC. , LEE, Moo-Seok , YOON, Joon-Khee , CHOI, Sung-Hak , SHIN, Yong-Cheol
发明人： LEE, Moo-Seok , YOON, Joon-Khee , CHOI, Sung-Hak , SHIN, Yong-Cheol
IPC分类号： B01D71/00
CPC分类号： B01D69/087 , B01D69/10 , B01D69/12 , B01D71/34 , B01D71/68 , B01D2325/40
摘要： A tubular braid and a composite hollow fiber membrane using the same are disclosed. The tubular braid is made by braiding yarns, the yarn made by combining thin filament and thick filament, wherein the thin filament is comprised of a plurality of monofilament having a fineness of 0.01 to 0.4 denier, and the thick filament is comprised of at least one monofilament having a fineness of 3 to 50 denier. Also, the composite hollow fiber membrane using the tubular braid of the present invention can realize excellent water permeability, high mechanical strength, good filtration reliability, great peeling strength, low dope permeation, and high stiffness.
摘要翻译：公开了一种管状编织物和使用其的复合中空纤维膜。管状编织物通过编织纱线制成，纱线通过组合细长丝和粗细丝而制成，其中细丝由多根细丝为0.01至0.4旦尼尔的单丝组成，并且粗丝由至少一个单丝的细度为3〜50旦。此外，使用本发明的管状编织物的复合中空纤维膜可以实现优异的透水性，高机械强度，良好的过滤可靠性，高剥离强度，低涂料透过性和高刚度。

9. 发明申请

WO2007018392A1 METHOD OF MANUFACTURING FOR AROMATIC POLYAMIDE COMPOSITE MEMBRANE 审中-公开
标题翻译：芳族聚酰胺复合膜的制备方法
公开(公告)号：WO2007018392A1
公开(公告)日：2007-02-15
申请号：PCT/KR2006/003101
申请日：2006-08-08
申请人： KOLON INDUSTRIES, INC , RYU, Jae Hee , CHOI, Sung Hak , LEE, Kwang Jin
发明人： RYU, Jae Hee , CHOI, Sung Hak , LEE, Kwang Jin
IPC分类号： C08J5/22
CPC分类号： C08J5/2275 , C08J2300/202
摘要： The present invention provides a method of manufacturing an aromatic polyamide composite membrane comprising: coating an aqueous solution containing polyfunctional aromatic amine to a porous polymer substrate; and reacting the coated substrate with an organic solution containing polyfunctional aromatic acyl halide to lead to interfacial condensation polymerization between the polyfunctional aromatic amine and the polyfunctional aromatic acyl halide so that the reaction product resulting from the interfacial condensation polymerization is coated on the surface of the substrate, characterized in that either of the aqueous solution containing polyfunctional aromatic amine or the organic solution containing polyfunctional aromatic acyl halide has dendritic polymer as one of polyfunctional compounds added thereto. The resulting aromatic polyamide composite membrane which includes dendrimer as polyfunctional compound, exhibits high salt rejection rate and water flux.
摘要翻译：本发明提供了一种制备芳族聚酰胺复合膜的方法，包括：将多官能芳族胺的水溶液涂布到多孔聚合物基材上; 并使涂覆的基材与含有多官能芳族酰卤的有机溶液反应，导致多官能芳族胺和多官能芳族酰卤之间的界面缩聚，从而将界面缩聚产生的反应产物涂覆在基材表面上其特征在于，含有多官能芳香族胺的水溶液或含有多官能芳香族酰卤的有机溶液中的任一种都具有作为添加了多官能化合物的树枝状聚合物。得到的芳香族聚酰胺复合膜，其包含作为多官能化合物的树枝状大分子，显示出高的脱盐率和水通量。

10. 发明申请

WO2003017601A1 AN APPARATUS CONNECTED MULTI IP BROADBAND LINE AND PACKET ROUTING METHOD THEREOF 审中-公开
标题翻译：一种装置连接的多路IP宽带线及其分组路由方法
公开(公告)号：WO2003017601A1
公开(公告)日：2003-02-27
申请号：PCT/KR2002/001562
申请日：2002-08-19
申请人： SMALLBIG TECHNOLOGY INC. , CHOI, Sung-Hak , KIM, Jung-Hoon , CHO, Gug-Yong
发明人： CHOI, Sung-Hak , KIM, Jung-Hoon , CHO, Gug-Yong
IPC分类号： H04L12/66
CPC分类号： H04L12/5692 , H04L12/2801 , H04L69/16 , H04L69/165 , H04L69/40
摘要： This present invention aims to provide an apparatus supporting a plurality of broadband communication lines and packet routing method thereof, which is transferring packet of said Internet user via at least equal one communication line to be inspected and selected among said a plurality of communication line when Internet user requests Internet connection. This present invention in order to achieve said purpose provides an apparatus supporting a plurality of broadband communication lines and packet routing method thereof, comprising several steps of (a) acquiring bandwidth information of every communication line; (b) detecting said traffic status of corresponding communication line as result of ping response time by implementing ping test to said every communication line; and ( c ) transferring said distributed packet data to communication line with less amount of current traffic than maximum traffic by checking said communication lines when said user computer requests packet data. Furthermore, this present invention in order to achieve said purpose provides an apparatus supporting a plurality of broadband communication lines and packet routing method thereof, characterized as comprising: the step establishing maximum receivable traffic amount to each communication line by acquiring bandwidth information of said every communication line; and the step transferring distributed packet data to a plurality of communication lines by using packet mark of iptables available in OS kernel at departure point.
摘要翻译：本发明的目的在于提供一种支持多个宽带通信线路及其分组路由方法的装置，其通过至少相同的一个通信线路传送所述互联网用户的分组，以便当互联网在多个通信线路中被检查和选择时用户请求Internet连接。本发明为了实现上述目的，提供了一种支持多条宽带通信线路的装置及其分组路由方法，包括以下步骤：（a）获取每个通信线路的带宽信息; （b）通过对所述每个通信线路进行ping测试来检测对应通信线路的通信状况，作为ping响应时间的结果; 以及（c）当所述用户计算机请求分组数据时通过检查所述通信线路将所述分布式分组数据传送到具有比最大业务量少的当前业务的通信线路。此外，为了实现上述目的，本发明提供了一种支持多条宽带通信线路的装置及其分组路由方法，其特征在于包括：通过获取所述每个通信的带宽信息，对每条通信线路建立最大可接收业务量的步骤线; 以及通过使用在出发点的OS内核中可用的iptables的分组标记将分发的分组数据传送到多个通信线路的步骤。

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