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1. 发明申请

WO2006042077A2 SAMPLING MEDICAL IMAGES FOR VIRTUAL HISTOLOGY 审中-公开
标题翻译：抽样医学图像的虚拟组织
公开(公告)号：WO2006042077A2
公开(公告)日：2006-04-20
申请号：PCT/US2005036093
申请日：2005-10-07
申请人： VIATRONIX INC , CHEN DONGQING
发明人： CHEN DONGQING
IPC分类号： G06K9/00
CPC分类号： G06F19/325 , G06F17/30262 , G06F19/321 , G06T7/0012 , G06T7/11 , G06T2207/10072 , G06T2207/20101 , G06T2207/30032
摘要： A system (300, 400, 800) and method (100, 200) are provided for building a digital sample library of lesions or cancers from medical images, the system (300) including an image scanner (310), image visualization or reviewing equipment (320) in signal communication with the image scanner, a digital sample library database (332), and a network for data communication connected between the library, the reviewing equipment, and the at least one scanner; and the method (100) including acquiring patient medical images (112), detecting target lesions in the acquired patient medical images (114, 116, 118), extracting digital samples (120) of the detected target lesions, collecting pathological and histological results (124, 126) of the detected target lesions, collecting diagnostic results of the detected target lesions (128), performing model selection and feature extraction (122) for each digital sample of a lesion, and storing (130) each extracted digital sample for library evolution.
摘要翻译：提供了一种用于从医学图像构建病变或癌症的数字样本库的系统（300,400,800）和方法（100,200），所述系统（300）包括图像扫描仪（310），图像可视化或检查设备（320）与图像扫描器进行信号通信，数字样本库数据库（332）以及连接在库，审查设备和至少一个扫描仪之间的用于数据通信的网络; 和方法（100）包括获取患者医学图像（112），检测所获取的患者医学图像（114,116,118）中的目标损伤，提取检测到的目标损伤的数字样本（120），收集病理学和组织学结果（收集检测到的目标损伤（128）的诊断结果，针对损伤的每个数字样本执行模型选择和特征提取（122），以及将每个提取的数字样本存储（130）用于文库演化。

2. 发明申请

WO2005036457A2 VIRTUAL ENDOSCOPY METHODS AND SYSTEMS 审中-公开
标题翻译：虚拟内镜方法和系统
公开(公告)号：WO2005036457A2
公开(公告)日：2005-04-21
申请号：PCT/US2004/033888
申请日：2004-10-12
申请人： VIATRONIX INCORPORATED , CHEN, Dongqing , LAKARE, Sarang , KREEGER, Kevin , WAX, Mark, R. , KAUFMAN, Arie, E. , LIANG, Zhengrong
发明人： CHEN, Dongqing , LAKARE, Sarang , KREEGER, Kevin , WAX, Mark, R. , KAUFMAN, Arie, E. , LIANG, Zhengrong
IPC分类号： G06T
CPC分类号： G06T7/12 , G06F19/00 , G06T2207/10081 , G06T2207/20132 , G06T2207/30032
摘要： Imaging systems and methods for processing and rendering volumetric images of a selected organ for virtual endoscopy applications are provided, which enable visualization and navigation of the imaged organ from within a lumen/cavity of the organ. For example, methods are provided for preparing 3D volumetric images of colons for virtual endoscopy application which do not require administration of oral laxatives or suppositories for patient bowel preparation. In particular, an imaging method which can be implemented for virtual colonoscopy applications, includes a process of obtaining an image dataset comprising image data of a colon (step 11) that is prepared (step 10) to tag regions of colonic residue in a manner that enhances a contrast between tagged regions of colonic residue in a lumen of the colon and a colon wall; segmenting (step 12) a region of interest in the image dataset, the region of interest comprising the colon lumen, the colon wall, and regions of tagged residue in the colon lumen; electronically cleaning (step 13) the tagged residue in the colon lumen using a gradient feature data obtained from the image dataset using a maximum directional gradient feature analysis; and rendering (step 14) a volumetric image comprising an endoluminal view at a region within the imaged colon.
摘要翻译：提供用于处理和渲染用于虚拟内窥镜检查应用的所选器官的体积图像的成像系统和方法，其使得能够从器官的腔/腔内可视化和导航成像的器官。例如，提供了用于制备用于虚拟内窥镜检查应用的冒烟的3D体积图像的方法，其不需要口服泻药或栓剂用于患者肠道准备。特别地，可以实现用于虚拟结肠镜检查应用的成像方法包括获得包括结肠图像数据（步骤11）的图像数据集的处理（步骤11），其被制备（步骤10），以以下方式标记结肠残基的区域：增加结肠腔中结肠残留的标记区域与结肠壁之间的对比度; 分割（步骤12）图像数据集中的感兴趣区域，感兴趣区域包括结肠腔，结肠壁和结肠腔中标记残基的区域; 使用最大方向梯度特征分析从图像数据集获得的梯度特征数据电子清洗（步骤13）结肠腔中的标记残基; 以及渲染（步骤14）包括在成像的结肠内的区域的腔内视图的体积图像。

3. 发明申请

WO0229723A9 ENHANCED VIRTUAL NAVIGATION AND EXAMINATION 审中-公开
标题翻译：增强虚拟导航和检查
公开(公告)号：WO0229723A9
公开(公告)日：2003-02-20
申请号：PCT/US0130942
申请日：2001-10-02
申请人： UNIV NEW YORK STATE RES FOUND , KAUFMAN ARIE E , LIANG ZHENGRONG , WAX MARK R , BITTER INGMAR , CHEN DONGQING , DACHILLE FRANK IX , KREEGER KEVIN , LAKARE SARANG
发明人： KAUFMAN ARIE E , LIANG ZHENGRONG , WAX MARK R , BITTER INGMAR , CHEN DONGQING , DACHILLE FRANK IX , KREEGER KEVIN , LAKARE SARANG
IPC分类号： G01R33/32 , A61B5/00 , A61B5/055 , A61B6/03 , A61B8/00 , G01R33/54 , G06K9/44 , G06T5/00 , G06T7/00 , G06T7/60 , G06T17/00 , G06T19/00
CPC分类号： G06T19/20 , G06T7/12 , G06T7/62 , G06T7/64 , G06T15/08 , G06T15/10 , G06T2200/04 , G06T2207/10072 , G06T2207/20044 , G06T2207/20132 , G06T2207/30028 , G06T2207/30061 , G06T2207/30172 , G06T2210/41 , G06T2219/028 , G06T2219/2012
摘要： Virtual navigation (2255) and examination of virtual objects are enhanced using methods of insuring that an entire surface to be examined has been properly viewed. A user interface (Fig. 23) identifies regions which have not been subject to examination and provides a mechanism (2250) to route the user to these regions in the 3D display. Virtual examination is further improved by the use of measuring disks (905) to enhance quantitative measurements such as diameter, distance, volume and angle. Yet another enhancement to the virtual examination of objects is a method of electronic segmentation, or cleansing, which corrects for partial volume effects occurring in an object.
摘要翻译：虚拟导航（2255）和虚拟对象的检查是通过确保正确观察整个被检查表面的方法得到增强。用户界面（图23）识别未经检查的区域，并提供将用户路由到3D显示中的这些区域的机构（2250）。通过使用测量盘（905）进一步提高虚拟检查以增强诸如直径，距离，体积和角度的定量测量。对物体的虚拟检查的另一个增强是电子分割或清洁的方法，其校正在对象中发生的部分体积效应。

4. 发明申请

WO2005055137A2 VESSEL SEGMENTATION USING VESSELNESS AND EDGENESS 审中-公开
标题翻译：使用消费和消费的船舶分类
公开(公告)号：WO2005055137A2
公开(公告)日：2005-06-16
申请号：PCT/US2004/039698
申请日：2004-11-24
申请人： VIATRONIX INCORPORATED , CAI, Wenli , CHEN, Dongqing , DACHILLE IX, Frank, C.
发明人： CAI, Wenli , CHEN, Dongqing , DACHILLE IX, Frank, C.
IPC分类号： G06T
CPC分类号： G06K9/4609 , A61B5/02007 , A61B6/463 , A61B6/481 , A61B6/504 , G06K9/44 , G06K2009/00932 , G06K2209/05 , G06T7/0012 , G06T7/11 , G06T19/00 , G06T2207/10081 , G06T2207/30101 , G06T2210/41
摘要： A system (100) and corresponding method for vessel segmentation are provided, the system having an adapter (112, 128, 130) for receiving image data, a processor (102) in signal communication with the input adapter, a pre-processing unit (170) in signal communication with the processor for pre-processing the received image data, and a vessel segmentation unit (180) in signal communication with the processor for segmenting vessels using pre-processed data; and the corresponding method including receiving image data, pre-processing the received data, and segmenting vessels responsive to the pre-processed data.
摘要翻译：提供了一种用于血管分割的系统（100）和相应的血管分割方法，该系统具有用于接收图像数据的适配器（112,128,130），与输入适配器信号通信的处理器（102），预处理单元 170）与处理器进行信号通信以预处理所接收的图像数据;以及血管分割单元（180），其与处理器进行信号通信，用于使用预处理的数据来分割血管; 以及相应的方法，包括接收图像数据，预处理接收到的数据，以及响应于预处理的数据对容器进行分段。

5. 发明申请

WO2005055076A1 CALCIUM CLEANSING FOR VASCULAR VISUALIZATION 审中-公开
标题翻译：钙清洗用于血管可视化
公开(公告)号：WO2005055076A1
公开(公告)日：2005-06-16
申请号：PCT/US2004/039699
申请日：2004-11-24
申请人： VIATRONIX INCORPORATED , WENLI, Cai , CHEN, Dongqing
发明人： WENLI, Cai , CHEN, Dongqing
IPC分类号： G06F17/00
CPC分类号： G06K9/44 , A61B5/02007 , A61B6/463 , A61B6/481 , A61B6/504 , A61B6/5211 , G06K2209/05 , G06T7/0012 , G06T7/11 , G06T19/00 , G06T2207/10081 , G06T2207/30101 , G06T2210/41
摘要： A system (100) and corresponding method for vessel visualization are provided, the system having an input adapter (112, 128, 130) for receiving segmented vessel data, a processor (102) in signal communication with the input adapter, a vessel visualization unit (170) in signal communication with the processor for visualizing the vessel, and a calcium cleansing unit (180) in signal communication with the processor for removing the influences of calcium deposits from the visualized vessel; and the corresponding method including receiving segmented vessel data, visualizing a vessel in correspondence with the segmented vessel data, and cleansing calcium by removing the influences of calcium deposits from the visualized vessel.
摘要翻译：提供了一种用于容器可视化的系统（100）和相应的容器可视化方法，该系统具有用于接收分段血管数据的输入适配器（112,128,130），与输入适配器信号通信的处理器（102），血管可视化单元（170）与所述处理器进行信号通信以使所述容器可视化;以及钙清洁单元（180），其与所述处理器进行信号通信，以消除来自所述可视化容器的钙沉积物的影响; 以及相应的方法，包括接收分段血管数据，与分段血管数据相对应地观察血管，并通过去除可视化血管中钙沉积物的影响来清除钙。

6. 发明申请

WO2005055137A3 VESSEL SEGMENTATION USING VESSELNESS AND EDGENESS 审中-公开
标题翻译：使用消费和消费的船舶分类
公开(公告)号：WO2005055137A3
公开(公告)日：2006-07-20
申请号：PCT/US2004039698
申请日：2004-11-24
申请人： VIATRONIX INC , CAI WENLI , CHEN DONGQING , DACHILLE IX FRANK C
发明人： CAI WENLI , CHEN DONGQING , DACHILLE IX FRANK C
IPC分类号： G06K9/00 , A61B6/00 , G06F17/00 , G06T20060101 , G06T5/00 , G06T7/00 , G06T17/40 , H04L20060101
CPC分类号： G06K9/4609 , A61B5/02007 , A61B6/463 , A61B6/481 , A61B6/504 , G06K9/44 , G06K2009/00932 , G06K2209/05 , G06T7/0012 , G06T7/11 , G06T19/00 , G06T2207/10081 , G06T2207/30101 , G06T2210/41
摘要： A system (100) and corresponding method for vessel segmentation are provided, the system having an adapter (112, 128, 130) for receiving image data, a processor (102) in signal communication with the input adapter, a pre-processing unit (170) in signal communication with the processor for pre-processing the received image data, and a vessel segmentation unit (180) in signal communication with the processor for segmenting vessels using pre-processed data; and the corresponding method including receiving image data, pre-processing the received data, and segmenting vessels responsive to the pre-processed data.
摘要翻译：提供了一种用于血管分割的系统（100）和相应的血管分割方法，该系统具有用于接收图像数据的适配器（112,128,130），与输入适配器信号通信的处理器（102），预处理单元 170）与处理器进行信号通信以预处理所接收的图像数据;以及血管分割单元（180），其与处理器进行信号通信，用于使用预处理的数据来分割血管; 以及相应的方法，包括接收图像数据，预处理接收到的数据，以及响应于预处理的数据对容器进行分段。

7. 发明申请

WO0193745A3 COMPUTER AIDED VISUALIZATION, FUSION AND TREATMENT PLANNING 审中-公开
标题翻译：计算机辅助可视化，融合和治疗计划
公开(公告)号：WO0193745A3
公开(公告)日：2002-08-29
申请号：PCT/US0118353
申请日：2001-06-06
申请人： UNIV NEW YORK STATE RES FOUND , LIANG ZHENGRONG , CHEN DONGQING , LI BIN , ROQUE CLEMENTE T , SMOUHA ERIC E , KAUFMAN ARIE E , WAX MARK R , KREEGER KEVIN
发明人： LIANG ZHENGRONG , CHEN DONGQING , LI BIN , ROQUE CLEMENTE T , SMOUHA ERIC E , KAUFMAN ARIE E , WAX MARK R , KREEGER KEVIN
IPC分类号： A61B5/055 , A61B19/00 , A61B5/05
CPC分类号： A61B5/055 , A61B5/726 , A61B90/36 , A61B2090/364
摘要： Figure 5 is a pictorial diagram illustrating a branched section of a blood vessel with plaque build-up resulting in stenosis. From step 315, the lumen of the artery (500) can be extracted and the regions of possible stenosis (505) can be identified. The artery exhibits a first arterial section (510) which branches at a bifurcation point (515) into an internal arterial branch (520) and an external arterial branch (525). The bifurcation point (515) can be determined and selected as the control point for subsequent registration operations.
摘要翻译：图5是示出导致狭窄的具有斑块积聚的血管的分支部分的示意图。从步骤315，可以提取动脉（500）的内腔，并且可以识别出可能的狭窄区域（505）。动脉呈现在分叉点（515）处分支到内部动脉分支（520）和外部动脉分支（525）中的第一动脉部分（510）。可以确定分岔点（515）并将其选为后续注册操作的控制点。

8. 发明申请

WO0055814A3 SYSTEM AND METHOD FOR PERFORMING A THREE-DIMENSIONAL VIRTUAL SEGMENTATION AND EXAMINATION 审中-公开
标题翻译：执行三维虚拟分类和检查的系统和方法
公开(公告)号：WO0055814A3
公开(公告)日：2001-06-28
申请号：PCT/US0007352
申请日：2000-03-17
申请人： UNIV NEW YORK STATE RES FOUND , KAUFMAN ARIE E , LIANG ZHENGRONG , WAX MARK R , WAN MING , CHEN DONGQING
发明人： KAUFMAN ARIE E , LIANG ZHENGRONG , WAX MARK R , WAN MING , CHEN DONGQING
IPC分类号： A61B6/03 , A61B5/055 , G06T1/00 , G06T5/00 , G06T7/00 , G06T15/04 , G06T15/08 , G06T15/40 , G06T17/00 , G06T15/20 , G06T17/40
CPC分类号： G06T15/08 , G06K9/209 , G06K9/38 , G06K2209/05 , G06T7/0012 , G06T7/11 , G06T15/04 , G06T19/20 , G06T2207/10081 , G06T2207/20156 , G06T2207/30032 , G06T2210/28 , G06T2210/41 , G06T2219/2021
摘要： A system and method for generating a three-dimensional visualization image of an object such as an organ using volume visualization techniques and exploring the image using a guided navigation system which allows the operator to travel along a flight path and to adjust the view to a particular portion of the image of interest in order, for example, to identify polyps, cysts or other abnormal features in the visualized organ. An electronic biopsy can also be performed on an identified growth or mass in the visualized object. Virtual colonoscopy can be enhanced by electronically removing residual stool, fluid and non-colonic tissue from the image of the colon, by employing bowel preparation followed by image segmentation operations. Methods are also employed for virtually expanding regions of colon collapse using image segmentation results.
摘要翻译：一种用于使用体积可视化技术生成诸如器官的物体的三维可视化图像的系统和方法，并且使用导航系统探索图像，所述导航系统允许操作者沿着飞行路径行进并且将视图调整到特定的例如，为了识别可视化器官中的息肉，囊肿或其他异常特征，感兴趣的图像的一部分。电子活检也可以对可视化物体中的识别生长或质量进行。通过使用排便，然后进行图像分割操作，可以通过电子方式从结肠图像中去除残留的粪便，流体和非结肠组织来增强虚拟结肠镜检查。方法也用于使用图像分割结果实际扩大结肠崩溃区域。

9. 发明申请

WO2006042077A3 SAMPLING MEDICAL IMAGES FOR VIRTUAL HISTOLOGY 审中-公开
公开(公告)号：WO2006042077A3
公开(公告)日：2006-04-20
申请号：PCT/US2005/036093
申请日：2005-10-07
申请人： VIATRONIX INCORPORATED , CHEN, Dongqing
发明人： CHEN, Dongqing
IPC分类号： G06K9/00 , G06K9/36
摘要： A system (300, 400, 800) and method (100, 200) are provided for building a digital sample library of lesions or cancers from medical images, the system (300) including an image scanner (310), image visualization or reviewing equipment (320) in signal communication with the image scanner, a digital sample library database (332), and a network for data communication connected between the library, the reviewing equipment, and the at least one scanner; and the method (100) including acquiring patient medical images (112), detecting target lesions in the acquired patient medical images (114, 116, 118), extracting digital samples (120) of the detected target lesions, collecting pathological and histological results (124, 126) of the detected target lesions, collecting diagnostic results of the detected target lesions (128), performing model selection and feature extraction (122) for each digital sample of a lesion, and storing (130) each extracted digital sample for library evolution.

10. 发明申请

WO0156491A3 COMPUTER AIDED TREATMENT PLANNING 审中-公开
标题翻译：计算机辅助治疗计划
公开(公告)号：WO0156491A3
公开(公告)日：2002-02-21
申请号：PCT/US0103746
申请日：2001-02-05
申请人： UNIV NEW YORK STATE RES FOUND , LIANG ZHENGRONG , LI BIN , CHEN DONGQING , SMOUHA ERIC E , ROQUE CLEMENTE T , KAUFMAN ARIE E , WAX MARK R , KREEGER KEVIN
发明人： LIANG ZHENGRONG , LI BIN , CHEN DONGQING , SMOUHA ERIC E , ROQUE CLEMENTE T , KAUFMAN ARIE E , WAX MARK R , KREEGER KEVIN
IPC分类号： A61B10/00 , A61B10/02 , A61B19/00 , A61F2/00 , A61F2/18 , G06F19/00
CPC分类号： A61B90/36 , A61B10/02 , A61B34/10 , A61B2090/374 , A61F2/00 , A61F2002/183 , G06F19/324 , G06F19/3481 , G16H50/50
摘要： A method of computer aided treatment planning is performed by generating and manipulating a three dimensional (3D) image of a region which includes at least one anatomical structure for which treatment, such as surgery, biopsy, tissue component analysis, prothesis implantation, radiation, chemotherapy and the like, is contemplated. A virtual intervention, which simulates at least a portion of the contemplated treatment, is performed in the 3D image. The user can then determine the effect of the intervention and interactively modify the intervention for improved treatment results. Preferably, a warning is automatically provided if the intervention posses a risk of detrimental effect. The user can navigate through the contemplated region in the 3D image and asses the results. The treatment plans can be saved for comparison and post treatment evaluation.
摘要翻译：计算机辅助治疗计划的方法是通过生成和操纵包括至少一个解剖结构的区域的三维（3D）图像来进行的，对于该解剖结构，诸如手术，活组织检查，组织成分分析，假体植入，放射，化疗等等。在3D图像中执行模拟预期治疗的至少一部分的虚拟介入。然后，用户可以确定干预的效果并交互地修改干预以改善治疗结果。优选地，如果干预具有有害影响的风险，则自动提供警告。用户可以浏览3D图像中的预期区域并评估结果。治疗计划可以节省进行比较和治疗后评估。

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