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1. 发明申请

US20220389366A1 CELL CULTURE MONITORING SYSTEM 有权
公开(公告)号：US20220389366A1
公开(公告)日：2022-12-08
申请号：US17774348
申请日：2020-11-03
申请人： CEIDOS SA
发明人： Léonard Barras , Sébastien Walpen
IPC分类号： C12M1/34 , C12M1/00
摘要： A cell culture monitoring system comprising a monitoring apparatus for coupling to a culture tank containing a cell culture medium therein, and a fluid circulation system for fluidic coupling to the cell culture tank the fluid circulation system comprising a dielectrophoresis cartridge for connection to the cell culture tank via supply and return conduits, the dielectrophoresis cartridge comprising a base and an electrode support having electrodes in or on the electrode support, the electrodes configured for traveling wave dielectrophoresis and comprising a measurement zone arranged above a measuring chamber formed between the electrode support and a floor of the base forming a measuring chamber therebetween, whereby cells in a liquid medium flowing through the measuring chamber are subject to a traveling wave dielectrophoresis force orthogonal to a direction of flow of said liquid through said measuring chamber.

2. 发明公开

US20240228939A1 CELL CULTURE MONITORING SYSTEM AND DIELECTROPHORESIS CARTRIDGE 审中-公开
公开(公告)号：US20240228939A1
公开(公告)日：2024-07-11
申请号：US18559857
申请日：2022-05-05
申请人： CEIDOS SA
发明人： Léonard Barras , Sébastien Walpen
IPC分类号： C12M1/34 , C12M1/00 , C12M1/26 , C12M1/36 , C12M3/00 , G01N15/10 , G01N15/14 , G01N15/1434
CPC分类号： C12M41/46 , C12M23/22 , C12M23/42 , C12M29/06 , C12M33/04 , C12M41/48 , G01N15/1434 , G01N15/1459 , G01N15/1484 , G01N2015/1006 , G01N2015/1452
摘要： A cell culture monitoring system comprising a monitoring apparatus for coupling to a culture tank containing a cell culture medium therein, and a fluid circulation system for fluidic coupling to the cell culture tank the fluid circulation system comprising a dielectrophoresis cartridge for connection to the cell culture tank via supply and return conduits, the dielectrophoresis cartridge comprising a base and an electrode support having electrodes in or on the electrode support, the electrodes configured for travelling wave dielectrophoresis and comprising a measurement zone arranged above a measuring chamber formed between the electrode support and a floor of the base forming a measuring chamber therebetween, whereby cells in a liquid medium flowing through the measuring chamber are subject to a travelling wave dielectrophoresis force orthogonal to a direction of flow of said liquid through said measuring chamber.

3. 发明授权

US11912976B2 Cell culture monitoring system 有权
公开(公告)号：US11912976B2
公开(公告)日：2024-02-27
申请号：US17774348
申请日：2020-11-03
申请人： CEIDOS SA
发明人： Léonard Barras , Sébastien Walpen
IPC分类号： C12M1/36 , C12M1/00 , C12M1/34
CPC分类号： C12M41/36 , C12M23/22
摘要： A cell culture monitoring system comprising a monitoring apparatus for coupling to a culture tank containing a cell culture medium therein, and a fluid circulation system for fluidic coupling to the cell culture tank the fluid circulation system comprising a dielectrophoresis cartridge for connection to the cell culture tank via supply and return conduits, the dielectrophoresis cartridge comprising a base and an electrode support having electrodes in or on the electrode support, the electrodes configured for traveling wave dielectrophoresis and comprising a measurement zone arranged above a measuring chamber formed between the electrode support and a floor of the base forming a measuring chamber therebetween, whereby cells in a liquid medium flowing through the measuring chamber are subject to a traveling wave dielectrophoresis force orthogonal to a direction of flow of said liquid through said measuring chamber.

4. 发明申请

WO2022238235A1 CELL CULTURE MONITORING SYSTEM AND DIELECTROPHORESIS CARTRIDGE 审中-公开
公开(公告)号：WO2022238235A1
公开(公告)日：2022-11-17
申请号：PCT/EP2022/062178
申请日：2022-05-05
申请人： CEIDOS SA
发明人： BARRAS, Léonard , WALPEN, Sébastien
IPC分类号： G01N15/14 , B01L3/00 , G01N15/10 , G01N15/1434 , G01N15/1475 , G01N15/1484 , G01N2015/1006 , G01N2015/1452
摘要： A cell culture monitoring system (1) comprising a monitoring apparatus (3) for coupling to a culture tank (2) containing a cell culture medium (15) therein, and a fluid circulation system (4) for fluidic coupling to the cell culture tank (2) the fluid circulation system comprising a dielectrophoresis cartridge (5) for connection to the cell culture tank (2) via supply and return conduits (14a), (14b), the dielectrophoresis cartridge comprising a base (20) and an electrode support (19) having electrodes (21) in or on the electrode support (19), the electrodes configured for travelling wave dielectrophoresis and comprising a measurement zone (21 a) arranged above a measuring chamber (23b) formed between the electrode support (19) and a floor (26) of the base (20) forming a measuring chamber therebetween, whereby cells in a liquid medium flowing through the measuring chamber are subject to a travelling wave dielectrophoresis force orthogonal to a direction of flow of said liquid through said measuring chamber (23b), the monitoring apparatus (3) comprising a computing unit (9), an image capture system (7) connected to the computing unit (9), and a cartridge holder portion (28) for receiving said dielectrophoresis cartridge (5) such that the image capture system (7) may detect cells flowing through said measuring chamber (23b).

5. 发明申请

WO2021089558A1 CELL CULTURE MONITORING SYSTEM 审中-公开
公开(公告)号：WO2021089558A1
公开(公告)日：2021-05-14
申请号：PCT/EP2020/080836
申请日：2020-11-03
申请人： CEIDOS SA
发明人： BARRAS, Léonard , WALPEN, Sébastien
IPC分类号： C12M1/34 , C12M1/00
摘要： A cell culture monitoring system (1) comprising a monitoring apparatus (3) for coupling to a culture tank (2) containing a cell culture medium (15) therein, and a fluid circulation system (4) for fluidic coupling to the cell culture tank (2) the fluid circulation system comprising a dielectrophoresis cartridge (5) for connection to the cell culture tank (2) via supply and return conduits (14a), (14b), the dielectrophoresis cartridge comprising a base (20) and an electrode support (19) having electrodes (21) in or on the electrode support (19), the electrodes configured for travelling wave dielectrophoresis and comprising a measurement zone (21a) arranged above a measuring chamber (23b) formed between the electrode support (19) and a floor (26) of the base (20) forming a measuring chamber therebetween, whereby cells in a liquid medium flowing through the measuring chamber are subject to a travelling wave dielectrophoresis force orthogonal to a direction of flow of said liquid through said measuring chamber (23b), the monitoring apparatus (3) comprising a computing unit (9), an image capture system (7) connected to the computing unit (9), and a cartridge holder portion (28) for receiving said dielectrophoresis cartridge (5) such that the image capture system (7) may detect cells flowing through said measuring chamber (23b).

6. 发明公开

EP4089394A1 CELL CULTURE MONITORING SYSTEM 无效
公开(公告)号：EP4089394A1
公开(公告)日：2022-11-16
申请号：EP21173427.2
申请日：2021-05-11
申请人： Ceidos SA
发明人： BARRAS, Léonard , WALPEN, Sébastien
IPC分类号： G01N15/14 , G01N15/00 , G01N15/10 , B01L3/00
摘要： A cell culture monitoring system (1) comprising a monitoring apparatus (3) for coupling to a culture tank (2) containing a cell culture medium (15) therein, and a fluid circulation system (4) for fluidic coupling to the cell culture tank (2) the fluid circulation system comprising a dielectrophoresis cartridge (5) for connection to the cell culture tank (2) via supply and return conduits (14a), (14b), the dielectrophoresis cartridge comprising a base (20) and an electrode support (19) having electrodes (21) in or on the electrode support (19), the electrodes configured for travelling wave dielectrophoresis and comprising a measurement zone (21a) arranged above a measuring chamber (23b) formed between the electrode support (19) and a floor (26) of the base (20) forming a measuring chamber therebetween, whereby cells in a liquid medium flowing through the measuring chamber are subject to a travelling wave dielectrophoresis force orthogonal to a direction of flow of said liquid through said measuring chamber (23b), the monitoring apparatus (3) comprising a computing unit (9), an image capture system (7) connected to the computing unit (9), and a cartridge holder portion (28) for receiving said dielectrophoresis cartridge (5) such that the image capture system (7) may detect cells flowing through said measuring chamber (23b).

7. 发明公开

EP3819368A1 CELL CULTURE MONITORING SYSTEM 有权
公开(公告)号：EP3819368A1
公开(公告)日：2021-05-12
申请号：EP19208209.7
申请日：2019-11-08
申请人： Ceidos SA
发明人： BARRAS, Léonard , WALPEN, Sébastien
IPC分类号： C12M1/34 , C12M1/00
摘要： A cell culture monitoring system (1) comprising a monitoring apparatus (3) for coupling to a culture tank (2) containing a cell culture medium (15) therein, and a fluid circulation system (4) for fluidic coupling to the cell culture tank (2) the fluid circulation system comprising a dielectrophoresis cartridge (5) for connection to the cell culture tank (2) via supply and return conduits (14a), (14b), the dielectrophoresis cartridge comprising a base (20) and an electrode support (19) having electrodes (21) in or on the electrode support (19), the electrodes configured for travelling wave dielectrophoresis and comprising a measurement zone (21a) arranged above a measuring chamber (23b) formed between the electrode support (19) and a floor (26) of the base (20) forming a measuring chamber therebetween, whereby cells in a liquid medium flowing through the measuring chamber are subject to a travelling wave dielectrophoresis force orthogonal to a direction of flow of said liquid through said measuring chamber (23b), the monitoring apparatus (3) comprising a computing unit (9), an image capture system (7) connected to the computing unit (9), and a cartridge holder portion (28) for receiving said dielectrophoresis cartridge (5) such that the image capture system (7) may detect cells flowing through said measuring chamber (23b).

8. 发明专利

DK3819368T3 Cellekulturovervågningssystem 未知
公开(公告)号：DK3819368T3
公开(公告)日：2022-07-04
申请号：DK19208209
申请日：2019-11-08
申请人： CEIDOS SA
发明人： BARRAS LÉONARD , WALPEN SÉBASTIEN
IPC分类号： C12M1/34 , C12M1/00

9. 发明专利

AU2020379170B2 Cell culture monitoring system 未知
公开(公告)号：AU2020379170B2
公开(公告)日：2022-10-20
申请号：AU2020379170
申请日：2020-11-03
申请人： CEIDOS SA
发明人： BARRAS LÉONARD , WALPEN SÉBASTIEN
IPC分类号： C12M1/34 , C12M1/00
摘要： A cell culture monitoring system (1) comprising a monitoring apparatus (3) for coupling to a culture tank (2) containing a cell culture medium (15) therein, and a fluid circulation system (4) for fluidic coupling to the cell culture tank (2) the fluid circulation system comprising a dielectrophoresis cartridge (5) for connection to the cell culture tank (2) via supply and return conduits (14a), (14b), the dielectrophoresis cartridge comprising a base (20) and an electrode support (19) having electrodes (21) in or on the electrode support (19), the electrodes configured for travelling wave dielectrophoresis and comprising a measurement zone (21a) arranged above a measuring chamber (23b) formed between the electrode support (19) and a floor (26) of the base (20) forming a measuring chamber therebetween, whereby cells in a liquid medium flowing through the measuring chamber are subject to a travelling wave dielectrophoresis force orthogonal to a direction of flow of said liquid through said measuring chamber (23b), the monitoring apparatus (3) comprising a computing unit (9), an image capture system (7) connected to the computing unit (9), and a cartridge holder portion (28) for receiving said dielectrophoresis cartridge (5) such that the image capture system (7) may detect cells flowing through said measuring chamber (23b).

10. 发明专利

AU2020379170A1 Cell culture monitoring system 未知
公开(公告)号：AU2020379170A1
公开(公告)日：2022-05-05
申请号：AU2020379170
申请日：2020-11-03
申请人： CEIDOS SA
发明人： BARRAS LÉONARD , WALPEN SÉBASTIEN
IPC分类号： C12M1/34 , C12M1/00
摘要： A cell culture monitoring system (1) comprising a monitoring apparatus (3) for coupling to a culture tank (2) containing a cell culture medium (15) therein, and a fluid circulation system (4) for fluidic coupling to the cell culture tank (2) the fluid circulation system comprising a dielectrophoresis cartridge (5) for connection to the cell culture tank (2) via supply and return conduits (14a), (14b), the dielectrophoresis cartridge comprising a base (20) and an electrode support (19) having electrodes (21) in or on the electrode support (19), the electrodes configured for travelling wave dielectrophoresis and comprising a measurement zone (21a) arranged above a measuring chamber (23b) formed between the electrode support (19) and a floor (26) of the base (20) forming a measuring chamber therebetween, whereby cells in a liquid medium flowing through the measuring chamber are subject to a travelling wave dielectrophoresis force orthogonal to a direction of flow of said liquid through said measuring chamber (23b), the monitoring apparatus (3) comprising a computing unit (9), an image capture system (7) connected to the computing unit (9), and a cartridge holder portion (28) for receiving said dielectrophoresis cartridge (5) such that the image capture system (7) may detect cells flowing through said measuring chamber (23b).

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