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1. 发明申请

WO2003028904A1 DISPOSITIF ET PROCEDE DE PRODUCTION D'IMPULSIONS ULTRASONORES DE FORTE PRESSION 审中-公开
标题翻译：用于生产高压超声波脉冲的装置和方法
公开(公告)号：WO2003028904A1
公开(公告)日：2003-04-10
申请号：PCT/FR2002/003390
申请日：2002-10-04
申请人： INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - I. N. S. E. R. M. , CATHIGNOL, Dominique
发明人： CATHIGNOL, Dominique
IPC分类号： B06B1/02
CPC分类号： B06B1/0215
摘要： Le dispositif de production d'impulsions ultrasonores de forte pression conforme ô l'invention comporte une source ultrasonore comportant un transducteur (2) de type piézo-électrique muni d'électrodes (3) et présentant un sens (f1) de polarisation, et des moyens (4) d'application d'une tension électrique sur les électrodes (3) du transducteur ultrasonore (2), assurant pour obtenir l'émission d'une onde ultrasonore : l'application d'un champ électrique de sens (f2) opposé au sens (f1) de polarisation, puis l'application d'un champ électrique transitoire de même sens que celui de la polarisation (f1). Selon l'invention, les moyens (4) assurent l'application d'une tension électrique progressive avec un temps de montée pour créer un champ électrique de sens (f2) opposé au sens (f1) de polarisation, pendant une durée d'application inférieure ô celle conduisant ô la dépolarisation du transducteur ultrasonore piézo-électrique.
摘要翻译：本发明涉及一种用于生产高压超声波脉冲的装置，包括一个包括一个设置有电极（3）并具有偏振方向（f1）的压电换能器（2）的超声波源，以及用于在电极上施加电压的装置超声波换能器（2）的电极（3），用于产生超声发射：施加与偏振方向（f1）相反的方向（f2）的电场，然后施加与偏振方向（f1）。本发明的特征在于，装置（4）施加具有积聚时间的逐渐电压以产生与偏振方向（f1）相反的方向（f2）的电场，持续时间小于所产生的电场在压电换能器的去极化。

2. 发明申请

WO1991012093A1 METHOD AND DEVICE FOR GENERATING AN ULTRASONIC WAVE 审中-公开
标题翻译：用于产生超声波的方法和装置
公开(公告)号：WO1991012093A1
公开(公告)日：1991-08-22
申请号：PCT/FR1991000105
申请日：1991-02-12
申请人： L'OREAL , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE ... , ROUGNY, Elizabeth , QUERLEUX, Bernard , CHAPELON, Jean-Yves , CATHIGNOL, Dominique , LEVEQUE, Jean-Luc
发明人： L'OREAL , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE ...
IPC分类号： B06B01/06
CPC分类号： G01N29/24 , B06B1/0651 , G01N2291/0423 , G10K11/32
摘要： A method whereby a transducer (4) is electrically excited to produce ultrasonic waves which pass through the medium of interest, and the echoes from the interfaces in said medium are picked up and analyzed. A thick transducer (4) is used, the face of which is directed at said medium (M) and has a curved concave surface (5) to focus the ultrasonic wave in the medium to be studied (M), and to obtain good lateral resolution, while the device (6) for electrically exciting the transducer can apply a voltage increment (7) to said transducer in order to produce a pressure pulse.

3. 发明申请

WO1993001752A1 USE OF COMPOSITE PIEZOELECTRIC TRANSDUCER FOR ULTRASONIC THERAPY APPARATUS 审中-公开
标题翻译：复合压电传感器用于超声波治疗设备的应用
公开(公告)号：WO1993001752A1
公开(公告)日：1993-02-04
申请号：PCT/EP1992001534
申请日：1992-07-08
申请人： TECHNOMED INTERNATIONAL , INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA ... , CHAPELON, Jean-Yves , CATHIGNOL, Dominique , BLANC, Emmanuel
发明人： TECHNOMED INTERNATIONAL , INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA ...
IPC分类号： A61B17/22
CPC分类号： A61N7/022 , A61B17/22012 , A61B17/2202 , A61B2017/00274 , A61B2017/22021 , A61B2017/22025 , A61B2017/22028 , A61B2018/00547 , A61N7/02 , A61N2007/0078 , A61N2007/0095 , B06B1/06
摘要： The invention relates to a composite piezoelectric transducer for making an acoustic or an ultrasonic therapeutic apparatus. The transducer may be a single large-size transducer or it may be a multi-transducer device and it advantageously emits ultrasonic waves that are focused on a focal point.

4. 发明申请

WO1990012658A1 PROCESS FOR MANUFACTURING AN ACOUSTIC SENSOR WITH AN ESSENTIALLY NON-DETACHABLE PROTECTIVE LAYER, AND ACOUSTIC SENSOR SO OBTAINED 审中-公开
标题翻译：用于制造具有基本不可拆卸保护层的声学传感器和获得的声学传感器的方法
公开(公告)号：WO1990012658A1
公开(公告)日：1990-11-01
申请号：PCT/FR1990000287
申请日：1990-04-23
申请人： TECHNOMED INTERNATIONAL S.A. , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE ... , MESTAS, Jean-Louis , CATHIGNOL, Dominique
发明人： TECHNOMED INTERNATIONAL S.A. , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE ...
IPC分类号： B06B01/06
CPC分类号： B06B1/0688 , G01H3/005 , Y10S310/80 , Y10T29/49005
摘要： The acoustic sensor comprises a piezoelectric film (12) mounted on a support (14) and connected electrically to electrodes (16, 18) themselves connected by electric conductors (20, 22) to a measurement device. The assembly composed of the film (12) and its support (14) is covered with a monobloc polymerized covering layer (24), preferably electrically insulating, so that the part (24a) of the covering layer (24) above the film (12) forms a protective layer which is rendered non-detachable or virtually non-detachable, by the piezoelectric film (12). The process for manufacturing this sensor is extremely simple and economical and the protective layer is non-detachable.

5. 发明申请

WO1983003749A1 BODY PROBE WITH OSCILLATING BEAM 审中-公开
标题翻译：身体探针与振荡光束
公开(公告)号：WO1983003749A1
公开(公告)日：1983-11-10
申请号：PCT/FR1983000075
申请日：1983-04-21
申请人： FOURCADE, Jacqueline, née MICHELLAND (heir of ... , FOURCADE, Delphine (heir of FOURCADE, Claude ... , FOURCADE, Elodie (heir of FOURCADE, Claude ... , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE ... , LENZ, Peter , CATHIGNOL, Dominique , CHAPELON, Jean-Yves
发明人： FOURCADE, Jacqueline, née MICHELLAND (heir of ... , FOURCADE, Delphine (heir of FOURCADE, Claude ... , FOURCADE, Elodie (heir of FOURCADE, Claude ... , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE ... , FOURCADE, Claude (deceased)
IPC分类号： A61B10/00
CPC分类号： A61B8/12 , A61B8/4461
摘要： The body probe having an oscillating beam comprises: a support (5) secured in a tube (1), a transmitter (7) arranged so as to oscillate in the tube (1), a bimetal strip (14) attached to the support (5) and remotely supplied with electric power, a unit (26) for transforming the deformation of the bimetal strip (14) and for transmitting an oscillation motion to the transmitter (7). Medical application to intra-corporeal probes.

6. 发明申请

WO1994017514A1 THERAPY APPARATUS WITH VARIABLE FOCALIZATION WITHOUT SECONDARY FOCALIZATION 审中-公开
标题翻译：不间断聚焦的治疗装置
公开(公告)号：WO1994017514A1
公开(公告)日：1994-08-04
申请号：PCT/FR1994000070
申请日：1994-01-21
申请人： TECHNOMED INTERNATIONAL , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE , CHAPELON, Jean-Yves , CATHIGNOL, Dominique , BLANC, Emmanuel
发明人： TECHNOMED INTERNATIONAL , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
IPC分类号： G10K11/34
CPC分类号： G10K11/341 , A61F7/00 , A61N7/02
摘要： The invention relates to a dynamic focalization method as well as to a therapy apparatus (10) for implementation. The therapy apparatus (10) comprises a therapy device (20) including at least an ultrasonic therapeutic transducer element (221-230) and a signal generator (50) delivering an electronic signal to said ultrasonic transducer element (221-230), characterized in that the signal generator (50) delivers an electronic signal whose self-correlation function is of the DIRAC type. The invention provides for a dynamic electronic focalization without appearance of secondary focal areas.
摘要翻译：本发明涉及一种动态聚焦方法以及用于实施的治疗装置（10）。治疗装置（10）包括至少包括超声波治疗换能器元件（221-230）和向所述超声波换能器元件（221-230）传送电子信号的信号发生器（50）的治疗装置（20），其特征在于信号发生器（50）传送自相关函数为DIRAC类型的电子信号。本发明提供了动态电子聚焦而不出现二次焦点区域。

7. 发明申请

WO1993012742A1 ULTRASONIC THERAPY APPARATUS DELIVERING ULTRASONIC WAVES WITH THERMAL AND CAVITATIONAL EFFECTS 审中-公开
标题翻译：超声波治疗装置提供具有热和空气效应的超声波
公开(公告)号：WO1993012742A1
公开(公告)日：1993-07-08
申请号：PCT/FR1992001210
申请日：1992-12-21
申请人： TECHNOMED INTERNATIONAL , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE ... , CHAPELON, Jean-Yves , CATHIGNOL, Dominique , GELET, Albert , BLANC, Emmanuel
发明人： TECHNOMED INTERNATIONAL , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE ...
IPC分类号： A61F07/00
CPC分类号： A61N7/02 , A61B2017/22008 , A61B2017/22009 , A61F2007/0086
摘要： An ultrasonic therapy apparatus including at least one treatment device (12) with at least one piezoelectric transducer element (14) for at least performing said therapy in order to destroy a target (16) such as tissue, and a controller (22) for controlling said device (12). The controllers (20, 22) for controlling said device (12) cause the treatment device (12) to deliver two kinds of ultrasonic waves, namely a first or thermal kind having a predominantly thermal effect on the tissue (16) to be treated, and a second or cavitational kind having a predominantly cavitational effect thereon. Internal or external benign or malignant tumours in the body of a mammal (M) may thereby be ultrasonically treated.
摘要翻译：一种超声波治疗装置，包括具有至少一个压电换能器元件（14）的至少一个治疗装置（12），用于至少执行所述治疗以破坏诸如组织的靶（16），以及控制器（22），用于控制所述装置（12）。用于控制所述装置（12）的控制器（20,22）使得处理装置（12）将待处理的组织（16）上的两种超声波，即具有主要热效应的第一或热类型，以及其上具有主要空穴效应的第二或空穴物质。因此，可以对哺乳动物（M）体内的内部或外部良性或恶性肿瘤进行超声波处理。

8. 发明申请

WO1993008749A1 METHOD FOR REDUCING DAMAGE TO AND LESIONS OF SURFACES IN THE PROPAGATION FIELD OF HIGH-ENERGY PRESSURE WAVES, USING AN AGENT FOR REDUCING BUBBLE FORMATION CAUSED BY THE PRESSURE WAVES, AND PRESSURE WAVE GENERATING DEVICE FOR IMPLEMENTING SAID METHOD 审中-公开
标题翻译：用于减少由压力波导引起的泡沫形成的发动机的高能量压力波段的损伤和损伤的方法以及用于实施所述方法的压力波产生装置
公开(公告)号：WO1993008749A1
公开(公告)日：1993-05-13
申请号：PCT/FR1992001007
申请日：1992-10-28
申请人： TECHNOMED INTERNATIONAL , INSERM (Institut National de la Santé et de la ... , DELON-MARTIN, Chantal , CATHIGNOL, Dominique , CHAPELON, Jean-Yves , BLANC, Emmanuel
发明人： TECHNOMED INTERNATIONAL , INSERM (Institut National de la Santé et de la ...
IPC分类号： A61B17/22
CPC分类号： A61B17/2251 , A61B8/4281 , G10K11/02
摘要： A method for reducing damage and lesions at the interface between two solid or liquid media, particularly at the interface between a liquid medium and the tissue of a living being or a solid medium such as a membrane, or at the interface between a solid medium such as a membrane and the tissue of a living being, as well as an apparatus for implementing said method, are described. The apparatus includes a pressure wave generating device (12) provided with a membrane (16) defining a cavity which is completely filled with a coupling liquid (18). The inner (19) and outer (20) surfaces of the membrane (16) are coated with an agent (24) for reducing damage or lesions at said interface, said agent preferably consisting of a silicone oil. The method may be used in pressure wave generating apparatuses for performing extracorporeal treatments without causing damage or lesions, even when operating at maximum power.
摘要翻译：一种用于减少两种固体或液体介质之间的界面处的损伤和损伤的方法，特别是在液体介质和活体或固体介质（例如膜）的组织之间的界面处，或在固体介质如作为膜和生物体的组织以及用于实现所述方法的装置进行描述。该设备包括设置有膜（16）的压力波产生装置（12），该膜限定了完全填充有耦合液体（18）的空腔。膜（16）的内部（19）和外部（20）表面涂覆有用于减少所述界面处的损伤或损伤的试剂（24），所述试剂优选由硅油组成。该方法可以用于压力波发生装置，用于进行体外治疗，而不会造成损伤或损伤，即使以最大功率运行。

9. 发明申请

WO1991010227A1 ELECTRICAL DISCHARGE DEVICE FOR A REDUCED INDUCTANCE LIQUID MEDIUM 审中-公开
标题翻译：用于减少电感液体介质的电子放电装置
公开(公告)号：WO1991010227A1
公开(公告)日：1991-07-11
申请号：PCT/FR1990000955
申请日：1990-12-28
申请人： TECHNOMED INTERNATIONAL , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE ... , CATHIGNOL, Dominique , MESTAS, Jean-Louis , DANCER, Paul
发明人： TECHNOMED INTERNATIONAL , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE ...
IPC分类号： G10K15/06
CPC分类号： G10K15/06
摘要： An electrical discharge device comprising an electrical discharge circuit (24) for a liquid discharge medium (18) between at least two electrodes (12, 14) immersed in said liquid medium, comprising an electrical discharge current source (20) and electric conductors (40, 42) connecting said current source to said electrodes through at least one discharge capacitor (30) located in said electrical circuit (24) between the current source (20) and said electrodes. The device is characterized in that it comprises a means (34) for reducing discharge circuit inductance additional to the coaxial arrangement of the electrode holders (13, 15). This electrical discharge device can be used in shock wave generator apparatus for generating more effective and reliably reproducible shock waves.

10. 发明申请

WO1989005026A1 DEVICE FOR GENERATING SHOCK WAVES FITTED WITH AN ELLIPSOIDAL REFLECTOR 审中-公开
标题翻译：用于产生用ELLIPSOIDAL反射器装配的冲击波的装置
公开(公告)号：WO1989005026A1
公开(公告)日：1989-06-01
申请号：PCT/FR1988000560
申请日：1988-11-15
申请人： TECHNOMED INTERNATIONAL S.A. , INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA ... , MESTAS, Jean-Louis , CATHIGNOL, Dominique , LACRUCHE, Bernard
发明人： TECHNOMED INTERNATIONAL S.A. , INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA ...
IPC分类号： G10K11/28
CPC分类号： G10K15/06 , G10K11/28
摘要： The invention concerns the process for manufacturing a device for generating shock waves which are felt only slightly, if at all, by patients. Said device comprises a truncated ellipsoidal reflector (12) having a (b)/(a) ratio > 0.60, preferably between 0.60 and 0.85, and a connection (14) for connecting the electrodes (6, 8) to an electric current source comprising a condensor (18) having a capacitance less than or equal to 500 nanofarads. The energy density of the emitted shock waves is thereby reduced at the level of the skin. Patients feel said waves only slightly, if at all, and can even be traited without anaesthesia.
摘要翻译：本发明涉及制造用于产生冲击波的装置的方法，该装置仅仅由患者感到轻微感觉。所述装置包括具有（b）/（a）比> 0.60，优选在0.60和0.85之间的截头椭圆反射器（12）和用于将电极（6,8）连接到电流源的连接（14），包括具有小于或等于500纳法的电容的冷凝器（18）。因此，在皮肤水平处，发射的冲击波的能量密度降低。患者感觉到只有轻微的波浪，如果有的话，甚至可以没有麻醉的特质。

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