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1. 发明专利

IL244554A Predicting breast cancer recurrence 未知
公开(公告)号：IL244554A
公开(公告)日：2020-08-31
申请号：IL24455416
申请日：2016-03-10
申请人： BIO THERANOSTICS INC , CATHERINE A SCHNABEL , DENNIS C SGROI , YI ZHANG , BROCK SCHROEDER , MARK G ERLANDER
发明人： CATHERINE A SCHNABEL , DENNIS C SGROI , YI ZHANG , BROCK SCHROEDER , MARK G ERLANDER
IPC分类号： A61P35/00 , C12Q1/6886
摘要： Provided are methods of determining risk of cancer recurrence in a subject afflicted with breast cancer. Also provided are methods of determining responsiveness to treatment of a subject afflicted with breast cancer. Additionally provided are methods of treating a subject afflicted with breast cancer.

2. 发明专利

IL276505D0 Predicting breast cancer recurrence 未知
公开(公告)号：IL276505D0
公开(公告)日：2020-09-30
申请号：IL27650520
申请日：2020-08-05
申请人： BIO THERANOSTICS INC , CATHERINE A SCHNABEL , DENNIS C SGROI , YI ZHANG , BROCK SCHROEDER , MARK G ERLANDER
发明人： CATHERINE A SCHNABEL , DENNIS C SGROI , YI ZHANG , BROCK SCHROEDER , MARK G ERLANDER
IPC分类号： A61P35/00 , C12Q1/6886
摘要： Provided are methods of determining risk of cancer recurrence in a subject afflicted with breast cancer. Also provided are methods of determining responsiveness to treatment of a subject afflicted with breast cancer. Additionally provided are methods of treating a subject afflicted with breast cancer.

3. 发明专利

IL276505A Predicting breast cancer recurrence 未知
公开(公告)号：IL276505A
公开(公告)日：2022-03-01
申请号：IL27650520
申请日：2020-08-05
申请人： BIO THERANOSTICS INC , CATHERINE A SCHNABEL , DENNIS C SGROI , YI ZHANG , BROCK SCHROEDER , MARK G ERLANDER
发明人： CATHERINE A SCHNABEL , DENNIS C SGROI , YI ZHANG , BROCK SCHROEDER , MARK G ERLANDER
IPC分类号： A61P35/00
摘要： Provided are methods of determining risk of cancer recurrence in a subject afflicted with breast cancer. Also provided are methods of determining responsiveness to treatment of a subject afflicted with breast cancer. Additionally provided are methods of treating a subject afflicted with breast cancer.

4. 发明专利

IL244554D0 Predicting breast cancer recurrence 未知
公开(公告)号：IL244554D0
公开(公告)日：2016-04-21
申请号：IL24455416
申请日：2016-03-10
申请人： BIO THERANOSTICS INC , CATHERINE A SCHNABEL , DENNIS C SGROI , YI ZHANG , BROCK SCHROEDER , MARK G ERLANDER
IPC分类号： C12Q20060101
摘要： Provided are methods of determining risk of cancer recurrence in a subject afflicted with breast cancer. Also provided are methods of determining responsiveness to treatment of a subject afflicted with breast cancer. Additionally provided are methods of treating a subject afflicted with breast cancer.

5. 发明申请

US20130281502A1 POST-TREATMENT BREAST CANCER PROGNOSIS 审中-公开
标题翻译：治疗后乳腺癌预后
公开(公告)号：US20130281502A1
公开(公告)日：2013-10-24
申请号：US13914617
申请日：2013-06-10
申请人： Dennis Sgroi , Mark G. Erlander , Yi Zhang , Catherine A. Schnabel
发明人： Dennis Sgroi , Mark G. Erlander , Yi Zhang , Catherine A. Schnabel
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/118 , C12Q2600/158
摘要： The disclosure includes the identification and use of gene expression profiles, or patterns, with clinical relevance to extended treatment and cancer-free survival in a patient. In particular, the disclosure includes the identities of genes that are expressed in correlation with benefit in a switch in endocrine therapy used to treat a patient. The levels of gene expression are disclosed as a molecular index for predicting clinical outcome, and so prognosis, for the patient. The disclosure further includes methods for predicting cancer recurrence, and/or predicting occurrence of metastatic cancer, after initial treatment with an anti-estrogen agent. The disclosure further includes methods for determining or selecting the treatment of a subject based upon the likelihood of life expectancy, cancer recurrence, and/or cancer metastasis.
摘要翻译：该公开内容包括鉴定和使用基因表达谱或模式，其与患者中延长的治疗和无癌生存具有临床相关性。具体地，本公开包括与用于治疗患者的内分泌治疗的转换中的益处相关表达的基因的身份。公开了基因表达水平作为预测临床结果的分子指标，并为患者预后。本发明还包括在用抗雌激素剂初次治疗后预测癌症复发和/或预测转移性癌症的发生的方法。本公开还包括基于预期寿命，癌症复发和/或癌症转移的可能性来确定或选择受试者的治疗的方法。

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