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2. 发明申请

WO1994025564A1 VIABLE BACTERIA 审中-公开
标题翻译：可视细菌
公开(公告)号：WO1994025564A1
公开(公告)日：1994-11-10
申请号：PCT/GB1994000811
申请日：1994-04-18
申请人： ZENECA LIMITED , RODHAM, David, Kirk , CANTWELL, John, Burnett
发明人： ZENECA LIMITED
IPC分类号： C12N01/04
CPC分类号： C12N1/04 , C12N11/04
摘要： Microbial cells are stabilised for storage in the form of a dried composition in a stasis state suspended in a collapsed matrix. The composition is prepared by mixing the microbial cells, for example Gram-negative bacterial cells such as Pseudomonas fluorescens, with an aqueous composition comprising a polyhydroxy compound, preferably a saccharide, from which the matrix will be derived, and drying the mixture under conditions such that viscous flow of the polyhydroxy compound occurs and the matrix collapses but does not unduly damage the cells. The glass transition temperature of the matrix is ideally above the temperature at which the composition is stored.
摘要翻译：稳定的微生物细胞以悬浮在收缩基质中的停滞状态的干燥组合物的形式存储。通过将微生物细胞，例如革兰氏阴性细菌细胞，例如荧光假单胞菌（Pseudomonas fluorescens）与包含多羟基化合物（优选糖）的水性组合物混合来制备组合物，从其中衍生基质，并在下列条件下干燥该混合物：发生多羟基化合物的粘性流动，并且基质崩溃，但不会不适当地损伤细胞。基质的玻璃化转变温度理想地高于组合物储存温度。

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