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1. 发明申请

WO2008108901A1 CHRONICALLY-IMPLANTABLE ACTIVE FIXATION MEDICAL ELECTRICAL LEADS AND RELATED METHODS FOR NON-FLUOROSCOPIC IMPLANTATION 审中-公开
标题翻译：慢性植入式有源固定型医用电线及相关方法非手术植入
公开(公告)号：WO2008108901A1
公开(公告)日：2008-09-12
申请号：PCT/US2007/089087
申请日：2007-12-28
申请人： MEDTRONIC, INC , MARKOWITZ, H. Toby , CAMPBELL-MASSA, Sean T. , SCANLON, David , KRYGER, Michael A
发明人： MARKOWITZ, H. Toby , CAMPBELL-MASSA, Sean T. , SCANLON, David , KRYGER, Michael A
IPC分类号： A61B5/053 , A61N1/05
CPC分类号： A61N1/0573 , A61B2034/2053 , A61N1/3627
摘要： Bio-impedance may be used for navigation systems to chronically implant pacing and defibrillation leads in the heart using a non-fluoroscopic position sensing unit (PSU), such as a modified LocaLisa® system from Medtronic Inc., which allows for variable frequency sampling of the position of electrode of a catheter. The PSU injects small AC signals via surface electrodes in three orthogonal axes, each on a slightly different frequency (e.g., near 30 KHz). Indwelling electrodes electrically connected to the PSU resolves the magnitude of induced voltage for each of the three frequencies, thus measuring voltage for each of the three axes. Voltages are divided by induced current to yield impedance in each axis for each electrode. Impedance is proportional to position within the body. Such a system requires that a conductive material, such as a retractable helical tip-electrode, be exposed during implantation. Since the tip is retracted during implantation, this disclosure provides a modified distal portion employing at least one aperture (or "window") for fluid exposure of the helix-electrode and a deployable internal sleeve for covering the aperture(s) when the helix-electrode is extended.
摘要翻译：生物阻抗可用于导航系统，以使用非荧光位置感测单元（PSU）长期地在心脏中植入起搏和除颤引线，例如来自Medtronic Inc.的经修改的LocaLisa系统，该系统允许对导管电极的位置。 PSU通过三个正交轴中的表面电极注入小的AC信号，每个在稍微不同的频率（例如，接近30KHz）处。电连接到PSU的留置电极解决三个频率中的每一个的感应电压的大小，从而测量三个轴中的每一个的电压。电压被感应电流除以每个电极的每个轴线产生阻抗。阻抗与体内的位置成比例。这样的系统需要在植入期间露出诸如可伸缩螺旋尖端电极的导电材料。由于尖端在植入期间缩回，本公开提供了一种修改的远侧部分，其采用至少一个用于螺旋电极的流体暴露的孔口（或“窗口”），以及可展开的内部套筒，电极延长。

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