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1. 发明授权

US08709217B2 Production of carbon nanostructures from functionalized fullerenes 有权
标题翻译：从功能化富勒烯生产碳纳米结构
公开(公告)号：US08709217B2
公开(公告)日：2014-04-29
申请号：US13128585
申请日：2009-11-09
申请人： Vijay Krishna , Brij M. Moudgil , Benjamin L. Koopman
发明人： Vijay Krishna , Brij M. Moudgil , Benjamin L. Koopman
IPC分类号： C01B31/00 , B01J19/12 , B82Y99/00 , B82Y40/00 , B82Y30/00
CPC分类号： C01B31/0226 , B82Y30/00 , B82Y40/00 , C01B32/152 , C01B32/16 , C01B32/18 , C01B32/25 , C01B2202/06 , C01B2202/34 , C01B2202/36 , Y10S977/752 , Y10S977/842 , Y10S977/902
摘要： Electromagnetic irradiation of functionalized fullerenes in an oxygen-free environment induces conversion of the functionalized fullerenes to carbon nanotubes, carbon nanohorns, carbon onions, diamonds and/or carbon schwarzites. The carbon nanotubes can be multi-wall carbon nanotubes. Advantageously, the subject invention can be used for in-situ synthesis of carbon nanostructures within a matrix to form a carbon nanostructure composite, where positioning of the carbon nanostructures is controlled by the manner of dispersion of the functionalized fullerenes in the matrix. Carbon nanotube comprising features, such as electrical connects, can be formed on a surface by irradiating a portion of a functionalized fullerene coating with a laser beam.
摘要翻译：在无氧环境中的功能化富勒烯的电磁辐射诱导官能化的富勒烯转化为碳纳米管，碳纳米角，碳鎓，金刚石和/或碳施瓦镁石。碳纳米管可以是多壁碳纳米管。有利地，本发明可用于在基质内原位合成碳纳米结构以形成碳纳米结构复合材料，其中通过官能化富勒烯在基质中分散的方式控制碳纳米结构的定位。通过用激光束照射功能化的富勒烯涂层的一部分，可以在表面上形成包括诸如电连接的特征的碳纳米管。

2. 发明申请

US20130039858A1 NIR MATERIALS AND NANOMATERIALS FOR THERANOSTIC APPLICATIONS 审中-公开
标题翻译：近红外材料及其应用的纳米材料
公开(公告)号：US20130039858A1
公开(公告)日：2013-02-14
申请号：US13582242
申请日：2011-02-24
申请人： Scott Chang Brown , Amit Kumar Singh , Parvesh Sharma , Brij M. Moudgil , Stephen R. Grobmyer
发明人： Scott Chang Brown , Amit Kumar Singh , Parvesh Sharma , Brij M. Moudgil , Stephen R. Grobmyer
IPC分类号： C07D487/22 , A61K49/22 , A61K49/10 , G01N21/64 , C01B33/18 , A61K49/00 , A61K49/04 , B82Y40/00 , B82Y15/00
CPC分类号： G01N33/54346 , A61K49/0032 , A61K49/0093 , C09B23/0041 , C09B23/0066 , C09B23/086 , C09B69/008 , G01N33/582
摘要： Novel fluorescent dye comprising metal oxide nanoparticles are prepared where the nanoparticles are as small as 3 nm or up to 7000 nm in diameter and where the dye is bound within the metal oxide matrix. In some embodiments the invention, novel dyes are covalently attached to the matrix and in other embodiments of the invention a dye is coordinate or ionic bound within the metal oxide matrix. A method for preparing the novel covalently bondable modified fluorescent dyes is presented. A method to prepare silica comprising nanoparticles that are 3 to 8 nm in diameter is presented. In some embodiments, the fluorescent dye comprising metal oxide nanoparticles are further decorated with functionality for use as multimodal in vitro or in vivo imaging agents. In other embodiments of the invention, the fluorescent dye comprising metal oxide nanoparticles provide therapeutic activity and incorporated therapeutic temperature monitoring.
摘要翻译：制备包含金属氧化物纳米颗粒的新型荧光染料，其中纳米颗粒直径小至3nm或至多7000nm，并且其中染料结合在金属氧化物基质内。在一些实施方案中，新颖的染料共价连接到基质上，在本发明的其它实施方案中，染料在金属氧化物基质内是配位或离子键合的。提出了一种制备新型共价键合修饰荧光染料的方法。提出了制备直径为3至8nm的纳米颗粒的制备二氧化硅的方法。在一些实施方案中，包含金属氧化物纳米颗粒的荧光染料进一步用功能性装饰用作多峰体外或体内成像剂。在本发明的其它实施方案中，包含金属氧化物纳米颗粒的荧光染料提供治疗活性并掺入治疗温度监测。

3. 发明申请

US20120123182A1 DEVICES FOR THERMALLY INDUCED TRANSFORMATIONS CONTROLLED BY IRRADIATION OF FUNCTIONALIZED FULLERENES 有权
标题翻译：通过功能化富勒烯辐射控制的热诱导变换装置
公开(公告)号：US20120123182A1
公开(公告)日：2012-05-17
申请号：US13106355
申请日：2011-05-12
申请人： VIJAY KRISHNA , Karl Zawoy , Brij M. Moudgil , Benjamin L. Koopman , Nathanael Ian Stevens , Kevin William Powers
发明人： VIJAY KRISHNA , Karl Zawoy , Brij M. Moudgil , Benjamin L. Koopman , Nathanael Ian Stevens , Kevin William Powers
IPC分类号： A61N5/00 , C08K5/17 , C08K5/10 , C08K5/3415 , A61K47/00 , A61K47/30 , A61K47/36 , A61K38/02 , A61K38/22 , A61K31/465 , A61K38/28 , A61K31/56 , A61K9/00 , A01N25/26 , C05F11/00 , F42D1/04 , C08K5/05 , B82Y30/00 , B82Y5/00
CPC分类号： A61K41/0052 , A61B18/18 , A61B18/1815 , A61N5/025 , A61N5/0601 , A61N5/062 , A61N5/10 , A61N2005/0659 , A61N2005/0661 , A61N2005/0662 , A61N2005/1098 , F42C19/08 , Y10S977/734 , Y10S977/902 , Y10S977/915 , Y10S977/931
摘要： An electromagnetic radiation activated device comprises a property changing material and at least one functionalized fullerene that upon irradiation of the functionalized fullerenes with electromagnetic radiation of one or more frequencies a thermally activated chemical or physical transformation occurs in the property changing material. The thermal activated transformation of the property changing material is triggered by the heating or combustion of the functionalized fullerenes upon their irradiation. The device can include a chemical agent that is embedded in the property changing material and is released when the material is heated by the functionalized fullerenes upon irradiation.
摘要翻译：电磁辐射激活装置包括性质改变材料和至少一种官能化富勒烯，当功能化富勒烯以一种或多种频率的电磁辐射照射时，在所述性质改变材料中发生热激活的化学或物理转变。性能改变材料的热激活转化是由于功能化的富勒烯在其照射下的加热或燃烧而触发的。该装置可以包括嵌入在性能改变材料中的化学试剂，并且当材料在照射时被官能化富勒烯加热时被释放。

4. 发明申请

US20120015045A1 FUNCTIONALIZED FULLERENES AS ANTIFUNGAL AGENTS 有权
标题翻译：作为反兴奋剂的功能齐全的富勒烯
公开(公告)号：US20120015045A1
公开(公告)日：2012-01-19
申请号：US13258649
申请日：2010-04-01
申请人： Vijay Krishna , Brij M. Moudgil , Benjamin L. Koopman
发明人： Vijay Krishna , Brij M. Moudgil , Benjamin L. Koopman
IPC分类号： A01N31/16 , A01P3/00 , C07C39/17 , A61P31/10 , A01N59/16 , A61K31/05
CPC分类号： A01N45/00 , C01B32/152 , A01N25/00 , A01N59/00 , A01N59/16 , A01N2300/00
摘要： Functionalized fullerenes are used in a method of combating fungal growth on surfaces and treating fungal diseases of patients. Surfaces that can be treated by the materials comprising an effective amount of functionalized fullerenes include those of fruits, vegetables, harvested grains, plants, or plant seeds. The method of combating fungal growth on a surface can be augmented but is not dependent on irradiation of the surface by light. Functional fullerenes are employed in various dosage forms such as topical, ingestible or administration.
摘要翻译：功能性富勒烯用于对抗表面真菌生长并治疗患者真菌病的方法。可以由包含有效量的官能化富勒烯的材料处理的表面包括水果，蔬菜，收获的谷物，植物或植物种子的表面。可以增强在表面上对抗真菌生长的方法，但不依赖于光的照射。功能性富勒烯以各种剂型使用，例如局部，可食用或给药。

5. 发明申请

US20110112232A1 ENHANCEMENT OF ELECTRON SCAVENGING BY WATER-SOLUBLE FULLERENES 有权
标题翻译：通过水溶性电解液增强电子扫描
公开(公告)号：US20110112232A1
公开(公告)日：2011-05-12
申请号：US13000765
申请日：2009-06-24
申请人： Vijay Krishna , Brij M. Moudgil , Benjamin L. Koopman
发明人： Vijay Krishna , Brij M. Moudgil , Benjamin L. Koopman
IPC分类号： C08K3/18 , C07C39/14 , B01J31/38 , B01J31/26 , A61L2/08 , A61L2/10 , B82Y30/00
CPC分类号： C07C39/17 , B01J21/063 , B01J23/06 , B01J35/004 , B82Y10/00 , B82Y30/00 , B82Y40/00 , C01B32/15 , C01B32/152 , C07C2604/00 , H01L51/0047 , Y02E10/549
摘要： Polyhydroxyfullerenes (PHFs) having enhanced electron scavenging capabilities have a ratio of non-hydroxyl functional groups to hydroxyl functional groups that is less than or equal to 0.3. When combined with a semiconductor photocatalyst, such as titanium dioxide nanoparticles, the PHFs provide a photocatalyst for degradation of chemical and biological contaminates with an efficiency of at least twice that of titanium dioxide nanoparticles free of PHFs. The PRFs are included in these catalysts at a weight ratio to titanium dioxide of about 0.001 to about 0.003, whereas significantly lower and higher ratios do not achieve the highly improved photodegradation capability. PHFs outside of the desired structure are shown to be of little value for photodegradation, and can be inhibiting to the photocatalytic activity of TiO2. The enhanced electron scavenging PHFs can be employed as a component of materials for solar cells, field effect transistors, and radical scavengers.
摘要翻译：具有增强的电子清除能力的聚羟基富勒烯（PHF）具有小于或等于0.3的非羟基官能团与羟基官能团的比例。当与诸如二氧化钛纳米颗粒的半导体光催化剂组合时，PHF提供用于降解化学和生物污染物的光催化剂，其效率为不含PHF的二氧化钛纳米颗粒的至少两倍。这些催化剂中的PRF以与二氧化钛的重量比约0.001至约0.003包括在一起，而明显降低和较高的比率不能获得高度改善的光降解能力。显示出所需结构之外的PHF对于光降解没有什么价值，并且可以抑制TiO 2的光催化活性。增强的电子清除PHF可以用作太阳能电池，场效应晶体管和自由基清除剂的材料的组分。

6. 发明申请

US20110020228A1 TARGETED CELLULAR SELECTIVITY OF SURFACE ACTIVE MOLECULES 审中-公开
标题翻译：表面活性分子的目标细胞选择性
公开(公告)号：US20110020228A1
公开(公告)日：2011-01-27
申请号：US12865589
申请日：2009-02-02
申请人： Brij M. Moudgil , Manoj Varshney , Stephen R. Grobmyer
发明人： Brij M. Moudgil , Manoj Varshney , Stephen R. Grobmyer
IPC分类号： A61K49/00 , A61K31/765 , A61K31/20 , A61K31/201 , A61K31/23 , A61K31/231 , A61K36/47 , A61K36/889 , A61K36/899 , A61K31/341 , A61K31/08 , A61K31/355 , A61K31/7024 , A61K31/05 , A61K31/575 , A61K31/221 , A61K31/255 , A61P35/00
CPC分类号： A61K49/0017 , A61K31/765 , A61K47/543 , A61K47/60
摘要： A method for the treatment of cancer involves delivering a surface active agent to an organism, where the surface active agent selectively partitions to and kills cancer cells as opposed to healthy cells. The surface active agent can be an ionic or a non-ionic surfactant with a HLB of less than 29 or a mixture of surface active agents with a HLB of less than 40, where the hydrophobic portion is a lesser fraction of the surface active agent than the hydrophilic portion. A fluorescence method of detecting and locating cancer cells in an organism involves delivering a surface active agent, where the surface active agent includes a fluorescence moiety that upon selective partitioning of the surface active agent to the cancer cells and irradiation by a radiation source to excite the fluorescence moiety, a fluorescence emission is observed permitting the detection and location of the cancerous tissue by local volumes of relatively high intensity emission.
摘要翻译：用于治疗癌症的方法涉及将表面活性剂递送到生物体，其中与健康细胞相反，表面活性剂选择性地分隔并杀死癌细胞。表面活性剂可以是HLB小于29的离子或非离子表面活性剂或HLB小于40的表面活性剂的混合物，其中疏水部分是表面活性剂的较少部分，亲水部分。检测和定位生物体内的癌细胞的荧光方法包括递送表面活性剂，其中表面活性剂包括荧光部分，当将表面活性剂选择性分配到癌细胞时，通过辐射源照射以激发观察到荧光发射，允许通过相当高强度发射的局部体积检测和定位癌组织。

7. 发明授权

US4352731A Apparatus for selective wetting of particles 失效
标题翻译：用于选择性润湿颗粒的装置
公开(公告)号：US4352731A
公开(公告)日：1982-10-05
申请号：US220656
申请日：1980-12-29
申请人： Brij M. Moudgil , John G. Roeschlaub
发明人： Brij M. Moudgil , John G. Roeschlaub
IPC分类号： B03B1/04 , B07C5/342 , B03B1/00
CPC分类号： B03B1/04 , B07C5/3427
摘要： Apparatus and method for selective wetting of particles includes sizing of particles to a preselected size for enabling optical discrimination between desired particles having a relatively large surface area receptive to coating by a preselected wetting agent and undesired particles having a relatively small surface area receptive to coating by the preselected wetting agent. The particles are fed into a conditioning zone defined by the spray of wetting agent from at least one spray means, the spray of wetting agent being in sufficient quantity to impact and coat substantially all of the surface areas of the particles receptive to coating by the wetting agent. The means for feeding the particles into the conditioning zone is disposed outside the conditioning zone and preferably feeds the particles in an unsupported state into the conditioning zone.
摘要翻译：用于选择性润湿颗粒的装置和方法包括将颗粒的尺寸调整为预选尺寸，以使得能够对具有相当大的表面积的预期颗粒进行光学鉴别，所述表面积接受预选润湿剂的涂覆，以及具有相对较小的表面积的不期望的颗粒，预选润湿剂。将颗粒进料到由至少一种喷雾装置的润湿剂喷雾限定的调节区域中，润湿剂的喷雾量足以冲击和涂覆接受涂层的颗粒的基本上所有表面区域代理商用于将颗粒进料到调节区域的装置设置在调节区域的外部，并且优选将颗粒以无支撑状态进料到调节区域中。

8. 发明授权

US4284499A Apparatus for the float concentration of ore 失效
标题翻译：矿石浮选浓度仪
公开(公告)号：US4284499A
公开(公告)日：1981-08-18
申请号：US98363
申请日：1979-11-28
申请人： Brij M. Moudgil , Booker W. Morey
发明人： Brij M. Moudgil , Booker W. Morey
IPC分类号： B03D1/00 , B03D1/02 , B03D1/14 , B03D1/24
CPC分类号： B03D1/00 , B03D1/021 , B03D1/085 , B03D1/1406 , B03D1/1412 , B03D1/1475 , B03D1/24 , B03D1/028 , B03D1/06
摘要： An apparatus and a method for concentrating an ore to recover valuable minerals from the ore is disclosed. The apparatus is based upon flotation separation techniques and comprises a trough into which is fed a slurry of ore particles which have been conditioned with a flotation reagent. The trough has a side extending outwardly forming a downwardly sloping flat table. The slurry of conditioned ore particles flows out of the trough and downwardly along the sloping table. Positioned along the sloping table is a disperser for dispersing larger particles up and into the slurry, which larger particles are generally along the surface of the sloping table. The sloping table is equipped with at least one aerator positioned along the flow path of the slurry, downstream of the disperser which aerates the conditioned ore slurry. The particles coated with the flotation reagent form agglomerates with gas bubbles produced by the aerator. These agglomerates float at a higher level within the slurry than the non-coated, non-agglomerating ore particles. A splitter is positioned near an open end of the sloping table. The splitter height above the surface of the sloping table is adjustable for intersecting the conditioned ore slurry at differing levels. The splitter separates the agglomerative, coated particles floating at a higher level from the non-agglomerative, non-coated particles floating at a lower level in the slurry.
摘要翻译：公开了一种用于浓缩矿石以从矿石中回收有价值矿物的装置和方法。该设备基于浮选分离技术，并且包括槽，其中供给已经用浮选试剂调节的矿石颗粒的浆料。槽具有向外延伸的一侧，形成向下倾斜的平台。调节矿石颗粒的浆料从槽中流出并沿倾斜台向下流动。沿着倾斜台定位的是用于将较大颗粒分散到浆料中的分散器，其中较大的颗粒通常沿着倾斜台的表面。倾斜台配备有至少一个沿着浆料的流动路径定位的曝气器，在分散器的下游对调节的矿浆进行通气。涂有浮选试剂的颗粒与曝气器产生的气泡形成附聚物。这些附聚物在浆料内比未涂覆的非附聚矿石颗粒漂浮更高的水平。分流器位于倾斜台的开口端附近。倾斜台表面上方的分流器高度是可调节的，以便与不同水平的调节矿浆相交。分流器将在较高水平上漂浮的凝聚的涂覆颗粒与在浆液中较低水平漂浮的非附聚的未涂覆颗粒分离。

9. 发明授权

US09314027B2 Functionalized fullerenes as antifungal agents 有权
标题翻译：功能性富勒烯作为抗真菌剂
公开(公告)号：US09314027B2
公开(公告)日：2016-04-19
申请号：US13258649
申请日：2010-04-01
申请人： Vijay Krishna , Brij M. Moudgil , Benjamin L. Koopman
发明人： Vijay Krishna , Brij M. Moudgil , Benjamin L. Koopman
IPC分类号： A01N45/00 , A01N59/16 , C01B31/02
CPC分类号： A01N45/00 , C01B32/152 , A01N25/00 , A01N59/00 , A01N59/16 , A01N2300/00
摘要： Functionalized fullerenes are used in a method of combating fungal growth on surfaces and treating fungal diseases of patients. Surfaces that can be treated by the materials comprising an effective amount of functionalized fullerenes include those of fruits, vegetables, harvested grains, plants, or plant seeds. The method of combating fungal growth on a surface can be augmented but is not dependent on irradiation of the surface by light. Functional fullerenes are employed in various dosage forms such as topical, ingestible or administration.
摘要翻译：功能性富勒烯用于对抗表面真菌生长并治疗患者真菌病的方法。可以由包含有效量的官能化富勒烯的材料处理的表面包括水果，蔬菜，收获的谷物，植物或植物种子的表面。可以增强在表面上对抗真菌生长的方法，但不依赖于光的照射。功能性富勒烯以各种剂型使用，例如局部，可食用或给药。

10. 发明授权

US08373139B2 Optical luminescence of functionalized fullerenes in an oxygen free environment 有权
标题翻译：功能化富勒烯在无氧环境中的光学发光
公开(公告)号：US08373139B2
公开(公告)日：2013-02-12
申请号：US12810248
申请日：2009-01-05
申请人： Vijay Krishna , Brij M. Moudgil , Benjamin L. Koopman
发明人： Vijay Krishna , Brij M. Moudgil , Benjamin L. Koopman
IPC分类号： G01N21/64
CPC分类号： C09K11/06 , C09K2211/1011 , C09K2211/1416 , G01N2021/6432
摘要： Functionalized fullerenes, when excited at any of a broad range of wavelengths in an oxygen free environment, undergo luminescence. The oxygen sensitive luminescence of functionalized fullerenes is used for numerous applications including oxygen detection; irradiation induced healing of polymeric materials; and phosphors for optical location and display applications. The degradation of the functionalized fullerenes allows for the detection of oxygen by diminished luminescence when the fullerenes are exposed to an irradiation source, such as a laser beam, in the presence of oxygen. The luminescence from a portion of a surface of a material with functionalized fullerenes allows for the location of the surface containing a functionalized fullerene target in the absence of oxygen or to heat the object in the area irradiated that is exposed to oxygen. The localized heating can be used to repair defects to a material containing the functionalized fullerenes. Materials containing functionalized fullerenes can be used as phosphors in display applications.
摘要翻译：当无氧环境中的任何波长激发时，官能化的富勒烯经受发光。官能化富勒烯的氧敏感发光用于许多应用，包括氧气检测; 辐射诱导的聚合材料愈合; 和用于光学位置和显示应用的荧光体。官能化富勒烯的降解允许当富氧存在下，当富勒烯暴露于照射源（例如激光束）时，通过减少的发光来检测氧。具有官能化富勒烯的材料的表面的一部分的发光允许在不存在氧的情况下包含官能化的富勒烯靶的表面的位置或者在暴露于氧的被照射区域中加热物体。局部加热可用于将缺陷修复到含有官能化富勒烯的材料上。含有官能化富勒烯的材料可用作显示应用中的荧光体。

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