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1. 发明授权

US08574258B2 Occlusion device and method of use 有权
标题翻译：遮挡装置及使用方法
公开(公告)号：US08574258B2
公开(公告)日：2013-11-05
申请号：US12936666
申请日：2009-04-08
申请人： Michael Braun , John S. Geis , Brian M. Strauss , Jay A. Lenker
发明人： Michael Braun , John S. Geis , Brian M. Strauss , Jay A. Lenker
IPC分类号： A61M29/00
CPC分类号： A61B17/12022 , A61B17/1204 , A61B17/12045 , A61B17/12109 , A61B17/12172 , A61B2017/0042 , A61B2017/00862 , A61B2017/00867 , A61B2017/00986 , A61B2017/00995 , A61B2017/12127 , A61B2017/22038 , A61B2217/005
摘要： A device for protecting cerebral vessels or brain tissue during treatment of a carotid vessel includes a catheter having a distal portion, a proximal portion and a lumen extending therebetween, the catheter including first and second expandable areas provided over the length of the catheter. The device includes a first elongate member insertable longitudinally through the lumen of the catheter, the first elongate member being configured for stretching at least a portion of the catheter and causing one of the first and second expandable areas to transition from an expanded state to a collapsed state. The device further includes a second elongate member insertable longitudinally through the lumen of the catheter, the second elongate member being configured for stretching at least a portion of the catheter and causing the other of the first and second expandable areas to transition from an expanded state to a collapsed state.
摘要翻译：用于在颈动脉血管治疗期间保护脑血管或脑组织的装置包括具有远侧部分，近端部分和在其间延伸的内腔的导管，该导管包括设置在导管长度上的第一和第二可扩张区域。所述装置包括纵向通过所述导管的内腔插入的第一细长构件，所述第一细长构件构造成用于拉伸所述导管的至少一部分，并且使所述第一和第二可膨胀区域中的一个从膨胀状态转变为折叠状态州。所述装置还包括纵向延伸穿过所述导管的内腔的第二细长构件，所述第二细长构件被构造成用于拉伸所述导管的至少一部分并使所述第一和第二可扩张区域中的另一个从扩张状态转变为崩溃状态

2. 发明申请

US20120116350A1 TRANSLATION DILATOR AND STAND ALONE VASCULAR GUIDE CATHETER 审中-公开
标题翻译：翻译式脱水器和独立的血管导管
公开(公告)号：US20120116350A1
公开(公告)日：2012-05-10
申请号：US13178381
申请日：2011-07-07
申请人： Brian M. Strauss , Lynn Shimada , Serefino Torres , Jay A. Lenker
发明人： Brian M. Strauss , Lynn Shimada , Serefino Torres , Jay A. Lenker
IPC分类号： A61B17/22 , A61M25/14 , A61M29/02
CPC分类号： A61B17/22 , A61B2017/00305 , A61B2017/00309 , A61B2017/22084
摘要： Systems and methods for delivering implantable devices, catheters, or substances in or near and/or restoring flow through body lumens, such as blood vessel lumens are described. A catheter having a proximal portion of a first diameter and a distal portion of a second diameter (smaller than the first diameter) is advanced into a body lumen. The distal portion of the catheter is caused to expand to a diameter that is larger than the second diameter but no larger than the first diameter. A working device is then advanced out of the distal end of the catheter and used to remove obstructive matter, deliver an implantable device or substance and/or restore flow. The distal portion can be reduced in diameter prior to removal from the body. A stand alone, guide catheter is also disclosed possessing high resistance to kinking even with a very thin wall.
摘要翻译：描述了用于在体内流经或接近和/或恢复体内流体（例如血管腔）中输送可植入装置，导管或物质的系统和方法。具有第一直径的近端部分和第二直径（小于第一直径的远端部分）的导管进入体腔。引导导管的远端部扩大到比第二直径大但不大于第一直径的直径。然后将工作装置从导管的远端推出并用于去除阻塞物质，递送可植入装置或物质和/或恢复流动。远端部分可以在从身体移除之前直径减小。还公开了独立的引导导管，即使具有非常薄的壁也具有高抗扭结性。

3. 发明申请

US20120022572A1 OCCLUSION DEVICE AND METHOD OF USE 有权
标题翻译： OCCLUSION设备及其使用方法
公开(公告)号：US20120022572A1
公开(公告)日：2012-01-26
申请号：US12936666
申请日：2009-04-08
申请人： Michael Braun , John S. Geis , Brian M. Strauss , Jay A. Lenker
发明人： Michael Braun , John S. Geis , Brian M. Strauss , Jay A. Lenker
IPC分类号： A61M29/00
CPC分类号： A61B17/12022 , A61B17/1204 , A61B17/12045 , A61B17/12109 , A61B17/12172 , A61B2017/0042 , A61B2017/00862 , A61B2017/00867 , A61B2017/00986 , A61B2017/00995 , A61B2017/12127 , A61B2017/22038 , A61B2217/005
摘要： A device for protecting cerebral vessels or brain tissue during treatment of a carotid vessel includes a catheter having a distal portion, a proximal portion and a lumen extending therebetween, the catheter including first and second expandable areas provided over the length of the catheter. The device includes a first elongate member insertable longitudinally through the lumen of the catheter, the first elongate member being configured for stretching at least a portion of the catheter and causing one of the first and second expandable areas to transition from an expanded state to a collapsed state. The device further includes a second elongate member insertable longitudinally through the lumen of the catheter, the second elongate member being configured for stretching at least a portion of the catheter and causing the other of the first and second expandable areas to transition from an expanded state to a collapsed state.
摘要翻译：用于在颈动脉血管治疗期间保护脑血管或脑组织的装置包括具有远侧部分，近端部分和在其间延伸的内腔的导管，该导管包括设置在导管长度上的第一和第二可扩张区域。所述装置包括纵向通过所述导管的内腔插入的第一细长构件，所述第一细长构件构造成用于拉伸所述导管的至少一部分，并且使所述第一和第二可膨胀区域中的一个从膨胀状态转变为折叠状态州。所述装置还包括纵向延伸穿过所述导管的内腔的第二细长构件，所述第二细长构件被构造成用于拉伸所述导管的至少一部分并使所述第一和第二可扩张区域中的另一个从扩张状态转变为崩溃状态

4. 发明授权

US6030397A Miniaturized medical brush 有权
标题翻译：小型医用刷
公开(公告)号：US6030397A
公开(公告)日：2000-02-29
申请号：US217785
申请日：1998-12-21
申请人： Richard R. Monetti , Robert A. Pecor , Thomas R. Sternweiler , Brian M. Strauss
发明人： Richard R. Monetti , Robert A. Pecor , Thomas R. Sternweiler , Brian M. Strauss
IPC分类号： A61B17/22 , A61B17/32 , A61B17/00
CPC分类号： A61B17/320758 , A61B2017/320012 , A61B2017/320733
摘要： A miniaturized brush particularly adapted for medical use formed at the distal end of an elongated brush drive shaft having a hollow lumen formed therein for introduction over a guidewire. The brush drive shaft is enclosed in the lumen of a brush delivery catheter and other components of a brush sub-assembly adapted to deliver infusate through the catheter lumen and to be coupled to a drive motor unit for rotating the brush drive shaft and brush. The brush bristles of the distal brush are adapted to be garaged in a distal end section of the brush delivery catheter lumen during introduction through a body lumen. The brush bristles are formed of a thin sheet of rigid plastic material that is shaped to have a plurality of fringe elements extending in parallel from a mounting web. The mounting web is wound about and attached to a distal end section of the drive shaft outer circumference so that the fringe elements extend outward from the drive shaft surface and obliquely of the drive shaft axis. Preferably, proximal and distal spiral brush sections are formed in this manner so that fluids are impelled distally and proximally, respectively, between the proximal and distal brush sections as infusate is delivered.
摘要翻译：一种特别适用于医疗用途的微型电刷，形成在细长刷驱动轴的远端，其具有形成在其中的中空腔，用于引导导丝。电刷驱动轴被封闭在电刷输送导管的内腔中，并且刷子子组件的其它部件适于通过导管管腔传送输液，并且连接到用于旋转刷驱动轴和刷子的驱动马达单元。远端刷的刷毛适于在通过体腔的引入期间被储存在刷递送导管腔的远端部分中。刷毛由一片刚性塑料材料制成，其形状为具有从安装幅材平行延伸的多个边缘元件。安装网缠绕并附接到驱动轴外周的远端部分，使得边缘元件从驱动轴表面向外延伸并且驱动轴轴线倾斜。优选地，以这种方式形成近端螺旋刷部分和远端螺旋刷部分，使得流体在分泌物输送时在近端和远端刷部分之间分别向远侧和近侧推进。

5. 发明申请

US20110264132A1 MULTI-UTILITARIAN MICROCATHETER SYSTEM AND METHOD OF USE 审中-公开
标题翻译：多功能微阵列系统及其使用方法
公开(公告)号：US20110264132A1
公开(公告)日：2011-10-27
申请号：US12936326
申请日：2009-04-03
申请人： Brian M. Strauss , Jeffrey J. Valko , Michael R. Henson
发明人： Brian M. Strauss , Jeffrey J. Valko , Michael R. Henson
IPC分类号： A61M29/00
CPC分类号： A61B17/320725 , A61B17/12022 , A61B17/12118 , A61B17/1214 , A61B17/12186 , A61B2017/00336 , A61B2017/12054 , A61B2017/22034 , A61B2017/22045 , A61B2017/2217 , A61M2025/0042
摘要： A device for performing therapeutic or diagnostic procedures within the cerebrovasculature includes a catheter having a distal portion, a proximal portion and a lumen extending therebetween, the catheter including an expandable region for engaging the vessel wall, thrombus, atheroma, or other structures. The device further includes an elongate stretching member, which can be a guidewire, insertable longitudinally through the lumen of the catheter, the elongate stretching member being configured for stretching at least a portion of the catheter and causing the expandable region to transition from an expanded state to a collapsed state, and wherein the elongate stretching member is retracted proximally relative to the catheter causes the expandable region to transition from the radially collapsed state to a radially, or laterally expanded state.
摘要翻译：用于在脑血管系统内执行治疗或诊断程序的装置包括具有远端部分，近端部分和在其间延伸的内腔的导管，该导管包括用于接合血管壁，血栓，动脉粥样化或其它结构的可扩张区域。该装置还包括细长的拉伸构件，其可以是纵向地插入导管内腔的导丝，细长的拉伸构件被构造成用于拉伸导管的至少一部分并使可扩张区域从扩张状态转变并且其中细长拉伸构件相对于导管向近侧缩回使得可扩张区域从径向收缩状态转变到径向或侧向膨胀状态。

6. 发明授权

US07018365B2 Threaded syringe with quick stop 有权
公开(公告)号：US07018365B2
公开(公告)日：2006-03-28
申请号：US10222478
申请日：2002-08-16
申请人： Brian M. Strauss , Brock H. Smith , Brian Canfield , Amanda Conner , Douglas R. Hayman , Ed Olsen
发明人： Brian M. Strauss , Brock H. Smith , Brian Canfield , Amanda Conner , Douglas R. Hayman , Ed Olsen
IPC分类号： A61M5/00 , A61M5/245 , B67D5/42
CPC分类号： A61M5/31586 , A61K9/0024 , A61K49/0419 , A61L24/001 , A61L24/046 , A61L24/06 , A61L24/08 , A61L2430/36 , A61M5/31566 , A61M2005/3139 , A61M2025/1052 , A61M2205/581 , A61M2205/582 , C08J3/091 , C08L29/04
摘要： A threaded syringe provides a mechanism by which a clinician can deliver a viscous fluid through a relatively small lumen and can obtain tactile or audible feedback of delivery. The threaded syringe allows for delivery of more viscous fluids with less force and/or allows for more controlled delivery. The syringe includes a syringe barrel and a sliding member positioned on the proximal end of the syringe barrel. The sliding member has a first threaded hole and a second hole. The sliding member is slidable on the syringe barrel between a first position at which the first threaded hole is aligned with the syringe barrel for precise delivery of a material from the syringe and a second position at which the second hole is aligned with the syringe barrel for filling of the syringe or to stop bleed out.

7. 发明授权

US06527732B1 Torsionally compensated guidewire 有权
标题翻译：扭转补偿导丝
公开(公告)号：US06527732B1
公开(公告)日：2003-03-04
申请号：US09690914
申请日：2000-10-17
申请人： Brian M. Strauss , Amanda M. Conner , Nelson Peralta
发明人： Brian M. Strauss , Amanda M. Conner , Nelson Peralta
IPC分类号： A61B500
CPC分类号： A61M25/09 , A61M2025/09083
摘要： A guidewire includes a core and a coil in composite cooperation to enable the guidewire to be used within tortuous regions of the vasculature. The core has a proximal region and a distal region. The distal region includes a flattened end and a tang for connecting the core to the coil. The coil has a proximal end, a distal end and a length extending between the proximal end and the distal end. The ratio between the proximal region and the coil diameter is 1.4:1 or greater. The guidewire includes three joints for attaching the coil to the core. A distal joint attaches the distal end of the coil to the flattened end of the core. A proximal joint attaches proximal end of the coil to the core. A medial joint attaches the length of the coil to the tang. The three joints cooperate with the 1.4:1 ratio to improve torque transmission ability of the guidewire to enable the guidewire to steer through vessels with bends of over 90 degrees and with lumen diameters of less than 3 mm.
摘要翻译：引导线包括复合材料中的芯和线圈，以使引导线能够在脉管系统的曲折区域内使用。芯具有近端区域和远端区域。远侧区域包括扁平端和用于将芯连接到线圈的柄脚。线圈具有近端，远端和在近端和远端之间延伸的长度。近端区域与线圈直径之比为1.4:1或更大。导线包括用于将线圈附接到芯的三个接头。远端接头将线圈的远端连接到芯的扁平端。近端接头将线圈的近端附接到芯部。内侧关节将线圈的长度连接到柄脚。三个接头配合1.4：1的比例，以提高导丝的扭矩传递能力，使引导线能够转向具有超过90度弯曲且管腔直径小于3 mm的血管。

8. 发明授权

US09078682B2 Systems and methods for removing obstructive matter from body lumens and treating vascular defects 有权
标题翻译：从体腔去除阻塞物并治疗血管缺陷的系统和方法
公开(公告)号：US09078682B2
公开(公告)日：2015-07-14
申请号：US13141177
申请日：2009-12-23
申请人： Jay A. Lenker , Brian M. Strauss , Lynn Miyeko Shimada
发明人： Jay A. Lenker , Brian M. Strauss , Lynn Miyeko Shimada
IPC分类号： A61B17/22 , A61M29/00 , A61B17/12 , A61M25/00 , A61B17/34 , A61B17/00 , A61B17/221 , A61M27/00
CPC分类号： A61B17/221 , A61B5/6858 , A61B17/12118 , A61B17/1214 , A61B17/12186 , A61B17/22 , A61B17/320725 , A61B17/3439 , A61B2017/00867 , A61B2017/12054 , A61B2017/22001 , A61B2017/22041 , A61B2017/22042 , A61B2017/22044 , A61B2017/22094 , A61B2017/2212 , A61B2217/005 , A61M25/0021 , A61M25/0023 , A61M25/0026 , A61M25/0043 , A61M25/0074 , A61M27/002 , A61M2025/0024
摘要： Systems and methods for removing obstructions from, delivering implantable devices or substances in or near and/or restoring flow through body lumens, such as blood vessel lumens. A catheter having a proximal portion of a first diameter and a distal portion of a second diameter (smaller than the first diameter) is advanced into a body lumen. The distal portion of the catheter is caused to expand to a diameter that is larger than the second diameter but no larger than the first diameter. A working device is then advanced out of the distal end of the catheter and used to remove obstructive matter, deliver an implantable device or substance and/or restore flow. The distal portion can be reduced in diameter prior to removal from the body.
摘要翻译：用于去除障碍物的系统和方法，在诸如血管腔之间的体腔内流动中或在其附近和/或恢复流体中输送可植入装置或物质。具有第一直径的近端部分和第二直径（小于第一直径的远端部分）的导管进入体腔。引导导管的远端部扩大到比第二直径大但不大于第一直径的直径。然后将工作装置从导管的远端推出并用于去除阻塞物质，递送可植入装置或物质和/或恢复流动。远端部分可以在从身体移除之前直径减小。

9. 发明申请

US20120101510A1 Systems And Methods For Removing Obstructive Matter From Body Lumens And Treating Vascular Defects 有权
标题翻译：用于从体腔去除阻塞物并治疗血管缺陷的系统和方法
公开(公告)号：US20120101510A1
公开(公告)日：2012-04-26
申请号：US13141177
申请日：2009-12-23
申请人： Jay A. Lenker , Brian M. Strauss , Lynn Miyeko Shimada
发明人： Jay A. Lenker , Brian M. Strauss , Lynn Miyeko Shimada
IPC分类号： A61B17/22 , A61M29/00
CPC分类号： A61B17/221 , A61B5/6858 , A61B17/12118 , A61B17/1214 , A61B17/12186 , A61B17/22 , A61B17/320725 , A61B17/3439 , A61B2017/00867 , A61B2017/12054 , A61B2017/22001 , A61B2017/22041 , A61B2017/22042 , A61B2017/22044 , A61B2017/22094 , A61B2017/2212 , A61B2217/005 , A61M25/0021 , A61M25/0023 , A61M25/0026 , A61M25/0043 , A61M25/0074 , A61M27/002 , A61M2025/0024
摘要： Systems and methods for removing obstructions from, delivering implantable devices or substances in or near and/or restoring flow through body lumens, such as blood vessel lumens. A catheter having a proximal portion of a first diameter and a distal portion of a second diameter (smaller than the first diameter) is advanced into a body lumen. The distal portion of the catheter is caused to expand to a diameter that is larger than the second diameter but no larger than the first diameter. A working device is then advanced out of the distal end of the catheter and used to remove obstructive matter, deliver an implantable device or substance and/or restore flow. The distal portion can be reduced in diameter prior to removal from the body.
摘要翻译：用于去除障碍物的系统和方法，在诸如血管腔之间的体腔内流动中或在其附近和/或恢复流体中输送可植入装置或物质。具有第一直径的近端部分和第二直径（小于第一直径的远端部分）的导管进入体腔。引导导管的远端部扩大到比第二直径大但不大于第一直径的直径。然后将工作装置从导管的远端推出并用于去除阻塞物质，递送可植入装置或物质和/或恢复流动。远端部分可以在从身体移除之前直径减小。

10. 发明授权

US6066152A Rotatable attachment mechanism for attaching a medical obstruction treatment device sub-assembly to a drive motor unit 有权
标题翻译：用于将医疗阻塞治疗装置子组件附接到驱动马达单元的可旋转附接机构
公开(公告)号：US6066152A
公开(公告)日：2000-05-23
申请号：US217784
申请日：1998-12-21
申请人： Brian M. Strauss , Charles J. Ricci , Robert A. Pecor
发明人： Brian M. Strauss , Charles J. Ricci , Robert A. Pecor
IPC分类号： A61B17/00 , A61B17/22 , A61B17/32
CPC分类号： A61B17/320758 , A61B2017/00477 , A61B2017/320012
摘要： A miniaturized obstruction treatment device, e.g., a resilient brush, particularly adapted for medical use formed at the distal end of an elongated brush drive shaft having a hollow lumen formed therein for introduction over a guidewire. The brush drive shaft is enclosed in the lumen of a brush delivery catheter, and the brush is adapted to be garaged in a distal end section of the brush delivery catheter lumen. A Y-connector and a brush sub-assembly connector are attached to the proximal end of the brush delivery catheter and form a brush sub-assembly with the brush drive shaft and brush. The Y-connector allows infusion of thrombolytic agents into the brush delivery catheter lumen for emission at the distal end opening thereof adjacent the brush. In use, the brush sub-assembly connector connects the brush sub-assembly with a drive motor unit connector of a drive motor unit. The drive motor unit receives the proximal end of the drive shaft and rotates it to rotate the brush bristles. The brush and brush drive shaft distal section are automatically extended out of the catheter lumen distal end opening when the sub-assembly connector and the drive motor unit connector positively lock together. Simultaneously, a drive hub of the brush drive shaft locks into a drive chuck of a drive motor unit to enable rotation of the drive shaft, and the drive shaft proximal end is seated in a dynamic seal that inhibits infiltration of blood and thrombolytic agent into the drive motor housing.
摘要翻译：特别适用于医疗用途的小型化阻塞治疗装置，例如形成在细长刷驱动轴的远端，具有形成在其中的中空腔，用于引导导丝。电刷驱动轴被封闭在电刷输送导管的内腔中，并且电刷适于在电刷输送导管管腔的远端部分中被储存。 Y型连接器和刷子组件连接器附接到刷递送导管的近端，并且与刷驱动轴和刷子形成刷子子组件。 Y型连接器允许将血栓溶解剂输注到刷递送导管管腔中，以在与刷子相邻的远端开口处发射。在使用中，刷子组件连接器将刷子组件与驱动电动机单元的驱动电机单元连接器相连。驱动马达单元接收驱动轴的近端并使其旋转以旋转刷毛。当子组件连接器和驱动电机单元连接器积极地锁定在一起时，刷和驱动轴远端部分自动延伸出导管内腔远端开口。同时，刷驱动轴的驱动轮毂锁定到驱动马达单元的驱动卡盘中以使得驱动轴能够旋转，并且驱动轴近端位于动态密封件中，该动态密封件阻止血液和溶血栓剂渗透入驱动电机外壳。

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