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1. 发明申请

US20120074844A1 SIGNAL GENERATION SYSTEM 有权
标题翻译：信号发生系统
公开(公告)号：US20120074844A1
公开(公告)日：2012-03-29
申请号：US13141938
申请日：2009-12-22
申请人： David Andrew York , Brian Halsall , Gregory Ian Chance
发明人： David Andrew York , Brian Halsall , Gregory Ian Chance
IPC分类号： H05H1/46 , H03H7/38
CPC分类号： H03H7/40
摘要： A signal generating system comprises a signal generator (14) for generating an electrical signal at a predetermined frequency; an impedance matching circuit (16), the electrical signal being supplied from the signal generator (14) via the impedance matching circuit (16) to a reactive load (10) in use; and an impedance matching control system (30) for detecting the electrical signal between the signal generator and the reactive load and for adjusting the impedance matching circuit (16) to achieve a predetermined condition. The impedance matching circuit control system (30) comprises a heterodyne circuit, and the system further comprises a heterodyne frequency generator (48) coupled to the signal generator (14) to generate a second, hetero-dyne frequency from the predetermined frequency from the signal generator. This second, heterodyne frequency is mixed with the detected signal to generate sum and difference signals. A filter (50, 52) passes the difference signal and a processor (Magnitude control; Phase control; 26; 28) responsive to the difference signal is used to adjust the impedance matching circuit (16) to achieve the predetermined condition.
摘要翻译：信号发生系统包括用于以预定频率产生电信号的信号发生器（14）阻抗匹配电路（16），电信号从信号发生器（14）通过阻抗匹配电路（16）提供给使用中的无功负载（10）; 以及阻抗匹配控制系统（30），用于检测信号发生器和无功负载之间的电信号，并用于调整阻抗匹配电路（16）以实现预定条件。阻抗匹配电路控制系统（30）包括外差电路，并且该系统还包括耦合到信号发生器（14）的外差频率发生器（48），以产生来自该信号的预定频率的第二异源晶体频率发电机。该第二个外差频率与检测信号混合，以产生和和差信号。滤波器（50,52）通过差分信号，并且响应于差分信号的处理器（幅度控制;相位控制; 26; 28）用于调整阻抗匹配电路（16）以实现预定条件。

2. 发明授权

US5240571A Quantitative method of detection of analytes in aqueous fluids by detection of NADH and NADPH 失效
标题翻译：通过检测NADH和NADPH检测含水液体中分析物的定量方法
公开(公告)号：US5240571A
公开(公告)日：1993-08-31
申请号：US690506
申请日：1991-04-24
申请人： William R. Heineman , Hua-Tang Tang , H. Brian Halsall , Amadeo J. Pesce
发明人： William R. Heineman , Hua-Tang Tang , H. Brian Halsall , Amadeo J. Pesce
IPC分类号： G01N27/49 , G01N33/487 , G01N33/94
CPC分类号： G01N33/94 , Y10S435/817
摘要： The concentration of NADH or NADPH in a test solution is determined by adding a redox coupling agent, preferably 2,6 dichloroindophenol DCIP, to the test solution. The coupling agent reacts with the NADH or NADPH to form an electroactive coupling agent (DCIPH.sub.2) which is then detected electrochemically at a lower voltage than would be required to detect the NADH or NADPH. This can be used to detect NADH or NADPH formed by any well known enzymatic or immunoassay method which produces NADH as a detectable product. This has particular application to biological fluids such as whole blood which does not require any treatment of the test sample prior to electrochemical analysis. In particular, red blood cells do not have to be removed from whole blood samples to provide reliable data.
摘要翻译：通过向测试溶液中加入氧化还原偶联剂，优选2,6-二氯靛酚DCIP来测定测试溶液中NADH或NADPH的浓度。偶联剂与NADH或NADPH反应形成电活性偶联剂（DCIPH 2），然后在比用于检测NADH或NADPH所需的电压更低的电压下进行电化学检测。这可以用于检测通过任何众所周知的产生NADH作为可检测产物的酶或免疫测定方法形成的NADH或NADPH。这特别适用于在电化学分析之前不需要对测试样品进行任何处理的生物流体如全血。特别是，红细胞不需要从全血样品中去除，以提供可靠的数据。

3. 发明申请

US20090170144A1 DETERMINATION OF VIABLE MICROORGANISMS USING COATED PARAMAGNETIC BEADS 审中-公开
标题翻译：使用涂层参考珠来确定可视化微生物
公开(公告)号：US20090170144A1
公开(公告)日：2009-07-02
申请号：US11816797
申请日：2006-02-22
申请人： William R. Heineman , Hallen Brian Halsall , Carl James Seliskar , Ismail Hakki Boyaci
发明人： William R. Heineman , Hallen Brian Halsall , Carl James Seliskar , Ismail Hakki Boyaci
IPC分类号： C12Q1/34 , C12Q1/04 , C12Q1/00
CPC分类号： G01N33/569 , C12Q1/04 , C12Q1/34 , C12Q2334/00 , G01N2333/924
摘要： The present invention relates to methods for the detection of microorganisms. In one embodiment, the present invention provides methods for detecting live microorganisms in a culture by capturing and culting the microorganisms on para-tropic-coated paramagnetic beads. This technique is useful for any application in which it is necessary to monitor the biological contamination level, for example drinking water, recreational waters, food processing waters and medical laboratories. In one embodiment, the method for determining the concentration of viable microorganisms in a sample according to the invention further comprises an inducer reagent, wherein the inducer reagent includes an inducer compound that induces the activity of an enzyme unique to the microorganism of interest.
摘要翻译：本发明涉及微生物检测方法。在一个实施方案中，本发明提供了通过在对热涂覆的顺磁珠上捕获和培养微生物来检测培养物中的活微生物的方法。这种技术对于需要监测生物污染水平的任何应用（例如饮用水，娱乐用水，食品加工水和医疗实验室）是有用的。在一个实施方案中，根据本发明的用于测定样品中活微生物浓度的方法还包括诱导剂试剂，其中所述诱导剂试剂包括诱导所述感兴趣的微生物特有的酶的活性的诱导剂化合物。

4. 发明授权

US07297312B2 Simultaneous multianalyte electrochemical assay based on spatial resolution 有权
标题翻译：基于空间分辨率的同时多分析电化学测定
公开(公告)号：US07297312B2
公开(公告)日：2007-11-20
申请号：US09268437
申请日：1999-03-12
申请人： Ying Ding , Brian Halsall , William R. Heineman
发明人： Ying Ding , Brian Halsall , William R. Heineman
IPC分类号： G01N27/00
CPC分类号： G01N33/5438 , Y10S435/971 , Y10S435/973
摘要： A simultaneous multianalyte electrochemical assay includes a cell which has a surface and the surface includes analyte binding sites i.e., antibodies or antigens on a solid phase at distinct separate locations. Separate working electrodes are located within proximity to these separate locations. Enzyme labeled antibodies or antigens depending on the assay format are added and the enzyme reaction product measured, by simultaneous amperometric measurement with the independent electrode in each area. The electrodes are spatially separated from adjacent analytes so that a measurement can be taken before cross-interference due to diffusion of product from adjacent analyte areas.
摘要翻译：同时多分析电化学测定包括具有表面的细胞，并且表面包括分析物结合位点，即在不同分离位置的固相上的抗体或抗原。单独的工作电极位于这些独立位置附近。添加根据测定形式的酶标记的抗体或抗原，并通过每个区域中的独立电极的同时电流测量来测量酶反应产物。电极在空间上与相邻的被分析物分开，从而可以在交叉干扰之前由于相邻分析物区域的产物扩散而进行测量。

5. 发明授权

US08643281B2 Signal generation system 有权
标题翻译：信号发生系统
公开(公告)号：US08643281B2
公开(公告)日：2014-02-04
申请号：US13141938
申请日：2009-12-22
申请人： Andrew David York , Brian Halsall , Gregory Ian Chance
发明人： Andrew David York , Brian Halsall , Gregory Ian Chance
IPC分类号： H05H1/46 , C23C16/00
CPC分类号： H03H7/40
摘要： A signal generating system comprises a signal generator (14) for generating an electrical signal at a predetermined frequency; an impedance matching circuit (16), the electrical signal being supplied from the signal generator (14) via the impedance matching circuit (16) to a reactive load (10) in use; and an impedance matching control system (30) for detecting the electrical signal between the signal generator and the reactive load and for adjusting the impedance matching circuit (16) to achieve a predetermined condition. The impedance matching circuit control system (30) comprises a heterodyne circuit, and the system further comprises a heterodyne frequency generator (48) coupled to the signal generator (14) to generate a second, heterodyne frequency from the predetermined frequency from the signal generator. This second, heterodyne frequency is mixed with the detected signal to generate sum and difference signals. A filter (50, 52) passes the difference signal and a processor (Magnitude control; Phase control; 26; 28) responsive to the difference signal is used to adjust the impedance matching circuit (16) to achieve the predetermined condition.
摘要翻译：信号发生系统包括用于以预定频率产生电信号的信号发生器（14）阻抗匹配电路（16），电信号从信号发生器（14）通过阻抗匹配电路（16）提供给使用中的无功负载（10）; 以及阻抗匹配控制系统（30），用于检测信号发生器和无功负载之间的电信号，并用于调整阻抗匹配电路（16）以实现预定条件。阻抗匹配电路控制系统（30）包括外差电路，并且系统还包括耦合到信号发生器（14）的外差频率发生器（48），以产生来自信号发生器的预定频率的第二外差频率。该第二个外差频率与检测信号混合，以产生和和差信号。滤波器（50,52）通过差分信号，并且响应于差分信号的处理器（幅度控制;相位控制; 26; 28）用于调整阻抗匹配电路（16）以实现预定条件。

6. 发明申请

US20120039217A1 INTERFACE MODULE AND CONTROLLER NETWORK 失效
标题翻译：接口模块和控制器网络
公开(公告)号：US20120039217A1
公开(公告)日：2012-02-16
申请号：US13254404
申请日：2010-03-03
申请人： Brian Halsall
发明人： Brian Halsall
IPC分类号： H04L12/28
CPC分类号： H04L29/06068 , G05B2219/21014 , H04L12/40032 , H04L12/40045 , H04L69/08 , H04L69/14 , Y02D50/30
摘要： An interface module is provided for connecting a device to a controller within a controller network. The controller is adapted to supply and/or receive data according to a network protocol, and the device is adapted to supply and/or receive data according to a device protocol. The interface module comprises: a network connector supporting a plurality of network channels for connecting the interface module to the controller via the controller network; a device connector supporting a plurality of device channels for connecting the interface module to the device; a conversion unit arranged to receive the plurality of network channels from the network connector, and adapted to convert data between the network protocol and the device protocol, the conversion unit having one or more signal terminals for supplying and/or receiving signals to or from the device; and a configuration unit between the conversion unit and the device connector, adapted to configure the interface module to the device by routing selected device channels to selected signal terminals of the conversion unit. The configuration unit is separable from and removably coupled to the conversion unit such that the interface module may be configured for use with a different device by replacement of the configuration unit. Also provided is a controller network comprising one or more devices and a controller for control of the devices, each of the devices being connected to the controller via an interface module.
摘要翻译：提供了一种用于将设备连接到控制器网络内的控制器的接口模块。控制器适于根据网络协议提供和/或接收数据，并且该设备适于根据设备协议来提供和/或接收数据。接口模块包括：网络连接器，其支持多个网络通道，用于经由控制器网络将接口模块连接到控制器; 支持用于将所述接口模块连接到所述设备的多个设备通道的设备连接器; 转换单元，布置成从所述网络连接器接收所述多个网络信道，并且适于在所述网络协议和所述设备协议之间转换数据，所述转换单元具有用于向或从所述网络协议提供和/或接收信号的一个或多个信号终端设备; 以及转换单元和设备连接器之间的配置单元，其适于通过将所选择的设备通道路由到转换单元的选定信号端子来将接口模块配置到设备。配置单元可分离并可拆卸地耦合到转换单元，使得接口模块可以被配置为通过替换配置单元与不同的设备一起使用。还提供了包括一个或多个设备的控制器网络和用于控制设备的控制器，每个设备经由接口模块连接到控制器。

7. 发明授权

US08787209B2 Interface module and controller network 失效
标题翻译：接口模块和控制器网络
公开(公告)号：US08787209B2
公开(公告)日：2014-07-22
申请号：US13254404
申请日：2010-03-03
申请人： Brian Halsall
发明人： Brian Halsall
IPC分类号： H04L12/28 , H04L29/06
CPC分类号： H04L29/06068 , G05B2219/21014 , H04L12/40032 , H04L12/40045 , H04L69/08 , H04L69/14 , Y02D50/30
摘要： An interface module is provided for connecting a device to a controller within a controller network. The controller is adapted to supply and/or receive data according to a network protocol, and the device is adapted to supply and/or receive data according to a device protocol. The interface module comprises: a network connector supporting a plurality of network channels for connecting the interface module to the controller via the controller network; a device connector supporting a plurality of device channels for connecting the interface module to the device; a conversion unit arranged to receive the plurality of network channels from the network connector, and adapted to convert data between the network protocol and the device protocol, the conversion unit having one or more signal terminals for supplying and/or receiving signals to or from the device; and a configuration unit between the conversion unit and the device connector, adapted to configure the interface module to the device by routing selected device channels to selected signal terminals of the conversion unit. The configuration unit is separable from and removably coupled to the conversion unit such that the interface module may be configured for use with a different device by replacement of the configuration unit. Also provided is a controller network comprising one or more devices and a controller for control of the devices, each of the devices being connected to the controller via an interface module.
摘要翻译：提供了一种用于将设备连接到控制器网络内的控制器的接口模块。控制器适于根据网络协议提供和/或接收数据，并且该设备适于根据设备协议来提供和/或接收数据。接口模块包括：网络连接器，其支持多个网络通道，用于经由控制器网络将接口模块连接到控制器; 支持用于将所述接口模块连接到所述设备的多个设备通道的设备连接器; 转换单元，布置成从所述网络连接器接收所述多个网络信道，并且适于在所述网络协议和所述设备协议之间转换数据，所述转换单元具有用于向或从所述网络协议提供和/或接收信号的一个或多个信号终端设备; 以及转换单元和设备连接器之间的配置单元，其适于通过将所选择的设备通道路由到转换单元的选定信号端子来将接口模块配置到设备。配置单元可分离并可拆卸地耦合到转换单元，使得接口模块可以被配置为通过替换配置单元与不同的设备一起使用。还提供了包括一个或多个设备的控制器网络和用于控制设备的控制器，每个设备经由接口模块连接到控制器。

8. 发明授权

US08738157B2 Controller network and method of controlling a controller network 有权
标题翻译：控制器网络和控制器网络的控制方法
公开(公告)号：US08738157B2
公开(公告)日：2014-05-27
申请号：US13254278
申请日：2010-03-03
申请人： Brian Halsall
发明人： Brian Halsall
IPC分类号： G05B11/01
CPC分类号： H04L29/06068 , G05B2219/21014 , H04L12/40032 , H04L12/40045 , H04L69/08 , H04L69/14 , Y02D50/30
摘要： A method of controlling a controller network is provided, the controller network comprising a plurality of devices, a controller for outputting control data to the devices, and a plurality of interface modules, each interface module being arranged to connect a respective device to the controller via the network. The method comprises: outputting, from the controller, a control message addressed to a first device, the control message corresponding to an action to be performed by the first device; receiving, at a first interface module connecting the first device to the network, the control message; storing the control message in a memory of the first interface module; broadcasting, from the controller, a trigger message addressed to at least the first device; receiving, at the first interface module, the trigger message; and passing, in response to the trigger message, the control message to the first device such that the action corresponding to the control message is performed. A corresponding controller network is also provided.
摘要翻译：提供了一种控制控制器网络的方法，所述控制器网络包括多个设备，用于向设备输出控制数据的控制器和多个接口模块，每个接口模块被布置为经由网络。该方法包括：从控制器输出寻址到第一设备的控制消息，该控制消息对应于要由第一设备执行的动作; 在连接所述第一设备到所述网络的第一接口模块处接收所述控制消息; 将所述控制消息存储在所述第一接口模块的存储器中; 从所述控制器广播到至少所述第一设备的触发消息; 在所述第一接口模块处接收所述触发消息; 以及响应于所述触发消息将所述控制消息传递到所述第一设备，使得执行与所述控制消息相对应的动作。还提供了相应的控制器网络。

9. 发明申请

US20120041572A1 CONTROLLER NETWORK AND METHOD OF CONTROLLING A CONTROLLER NETWORK 有权
标题翻译：控制器网络和控制器网络的控制方法
公开(公告)号：US20120041572A1
公开(公告)日：2012-02-16
申请号：US13254278
申请日：2010-03-03
申请人： Brian Halsall
发明人： Brian Halsall
IPC分类号： G05B15/00
CPC分类号： H04L29/06068 , G05B2219/21014 , H04L12/40032 , H04L12/40045 , H04L69/08 , H04L69/14 , Y02D50/30
摘要： A method of controlling a controller network is provided, the controller network comprising a plurality of devices, a controller for outputting control data to the devices, and a plurality of interface modules, each interface module being arranged to connect a respective device to the controller via the network. The method comprises: outputting, from the controller, a control message addressed to a first device, the control message corresponding to an action to be performed by the first device; receiving, at a first interface module connecting the first device to the network, the control message; storing the control message in a memory of the first interface module; broadcasting, from the controller, a trigger message addressed to at least the first device; receiving, at the first interface module, the trigger message; and passing, in response to the trigger message, the control message to the first device such that the action corresponding to the control message is performed. A corresponding controller network is also provided.
摘要翻译：提供了一种控制控制器网络的方法，所述控制器网络包括多个设备，用于向设备输出控制数据的控制器和多个接口模块，每个接口模块被布置为经由网络。该方法包括：从控制器输出寻址到第一设备的控制消息，该控制消息对应于要由第一设备执行的动作; 在连接所述第一设备到所述网络的第一接口模块处接收所述控制消息; 将所述控制消息存储在所述第一接口模块的存储器中; 从所述控制器广播到至少所述第一设备的触发消息; 在所述第一接口模块处接收所述触发消息; 以及响应于所述触发消息将所述控制消息传递到所述第一设备，使得执行与所述控制消息相对应的动作。还提供了相应的控制器网络。

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