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1. 发明申请

US20140050378A1 SYSTEM AND METHOD FOR DETECTING MATERIALS OR DISEASE STATES USING MULTI-ENERGY COMPUTED TOMOGRAPHY 审中-公开
标题翻译：使用多功能计算机图像检测材料或疾病状态的系统和方法
公开(公告)号：US20140050378A1
公开(公告)日：2014-02-20
申请号：US13585632
申请日：2012-08-14
申请人： Souma Sengupta , Sandeep Dutta , Toshihiro Rifu , Ajay Narayanan , Bipul Das , Melissa Megumi Shiraishi Kuriki , Pedro Alves Lemos Neto , Roberto Caldeira Cury , Carlos Eduardo Rochitte
发明人： Souma Sengupta , Sandeep Dutta , Toshihiro Rifu , Ajay Narayanan , Bipul Das , Melissa Megumi Shiraishi Kuriki , Pedro Alves Lemos Neto , Roberto Caldeira Cury , Carlos Eduardo Rochitte
IPC分类号： G06K9/00
CPC分类号： G06T11/008 , A61B6/032 , A61B6/12 , A61B6/405 , A61B6/481 , A61B6/482 , A61B6/503 , A61B6/504 , A61B6/5217 , A61B6/563 , G01N23/046 , G01N2223/419 , G01N2223/423 , G01N2223/612 , G06T2211/408
摘要： The disclosed embodiments relate to characterizing or quantifying an element or composition of interest within an imaged volume. In accordance with one embodiment, high and low energy images are acquired of a volume of interest using a polychromatic emission source. The high and low energy images are processed to generate monochromatic images. Based on the observed attenuation within the monochromatic images, one or more elements or compositions of interest are characterized within the imaged volume.
摘要翻译：所公开的实施例涉及在成像的体积内表征或量化感兴趣的元素或组成。根据一个实施例，使用多色发射源获取感兴趣体积的高能量和低能量图像。处理高能量和低能量图像以产生单色图像。基于在单色图像中观察到的衰减，在成像的体积内表征感兴趣的一种或多种元素或组合物。

2. 发明申请

US20140010427A1 APPARATUS AND METHOD FOR MULTI-ENERGY TISSUE QUANTIFICATION 有权
标题翻译：多功能组织数量的装置和方法
公开(公告)号：US20140010427A1
公开(公告)日：2014-01-09
申请号：US13542964
申请日：2012-07-06
申请人： Andras Kriston , Peter Alexander John Lamb , Paulo Ricardo dos Santos Mendonca , Masayuki Kudo , Kosuke Sasaki , Souma Sengupta , Rahul Bhotika , Laszlo Rusko , Bipul Das , Scott David Wollenweber , Ferenc Kovacs
发明人： Andras Kriston , Peter Alexander John Lamb , Paulo Ricardo dos Santos Mendonca , Masayuki Kudo , Kosuke Sasaki , Souma Sengupta , Rahul Bhotika , Laszlo Rusko , Bipul Das , Scott David Wollenweber , Ferenc Kovacs
IPC分类号： G06K9/00 , A61B6/03
CPC分类号： A61B6/482 , A61B6/032 , A61B6/12 , A61B6/481 , A61B6/50 , A61B6/5217
摘要： An apparatus for multi-energy tissue quantification includes an x-ray imaging system comprises an x-ray source configured to emit a beam of x-rays toward an object to be imaged, a detector configured to receive the x-rays attenuated by the object, and a data acquisition system (DAS) operably coupled to the detector. A computer operably connected to the x-ray source and the DAS is programmed to cause the x-ray source to emit x-rays at each of a first kVp and a second kVp toward the detector, acquire x-ray data from x-rays emitted at the first and second kVp through a region of interest (ROI), and perform a first multi-material decomposition based on the acquired x-ray data. The computer is also programmed to quantify a volume fraction of a first material in the ROI based on the first multi-material decomposition and display the volume fraction of the first material to a user.
摘要翻译：一种用于多能量组织定量的装置，包括：X射线成像系统，包括被配置为向待成像物体发射X射线束的x射线源;被配置为接收被物体衰减的x射线的检测器，以及可操作地耦合到检测器的数据采集系统（DAS）。可操作地连接到X射线源和DAS的计算机被编程为使x射线源在第一kVp和第二kVp的每一个处朝向检测器发射x射线，从x射线获取x射线数据通过感兴趣区域（ROI）在第一和第二kVp处发射，并且基于所获取的x射线数据执行第一多材料分解。计算机还被编程为基于第一多材料分解来量化ROI中的第一材料的体积分数，并将第一材料的体积分数显示给用户。

3. 发明申请

US20130272596A1 METHODS FOR GENERATING A RECONSTRUCTED TREE STRUCTURE FROM MEDICAL IMAGE DATA 有权
标题翻译：从医学图像数据生成重建树结构的方法
公开(公告)号：US20130272596A1
公开(公告)日：2013-10-17
申请号：US13448015
申请日：2012-04-16
申请人： Ziyue Xu , Fei Zhao , Roshni Rustom Bhagalia , Bipul Das
发明人： Ziyue Xu , Fei Zhao , Roshni Rustom Bhagalia , Bipul Das
IPC分类号： G06K9/00
CPC分类号： G06K9/469 , G06K2009/00932 , G06K2209/05 , G06T7/0012 , G06T7/162 , G06T7/215 , G06T2207/10081 , G06T2207/10104 , G06T2207/10116 , G06T2207/10132 , G06T2207/20076 , G06T2207/20081 , G06T2207/30101
摘要： A computer-implemented method of post-processing medical image data is provided. The method includes receiving tracked image data representative of multiple blood vessels, generating a binary tree structure for the multiple blood vessels based on a parent-child relationship between branches of the multiple blood vessels, generating a likelihood model for determining a validity of the branches of the multiple blood vessels, and generating a likelihood score for each branch based on the respective branch's compatibility with the likelihood model. The method also includes generating a reconstructed tree for the multiple blood vessels. Compatible branches are included in the reconstructed tree, while invalid branches are not included in the reconstructed tree.
摘要翻译：提供了计算机实现的后处理医学图像数据的方法。该方法包括接收代表多个血管的跟踪图像数据，基于多个血管的分支之间的亲子关系生成多个血管的二叉树结构，生成用于确定多个血管的分支的有效性的似然模型多个血管，并且基于相应分支与可能性模型的兼容性来生成每个分支的似然分数。该方法还包括为多个血管生成重建的树。重构树中包含兼容的分支，而重建树中不包括无效分支。

4. 发明授权

US08532744B2 Method and system for design of spectral filter to classify tissue and material from multi-energy images 有权
标题翻译：用于从多能量图像中分类组织和材料的光谱滤波器设计方法和系统
公开(公告)号：US08532744B2
公开(公告)日：2013-09-10
申请号：US13215634
申请日：2011-08-23
申请人： Bipul Das , Ajay Narayanan , Pratik Kamleshbhai Shah
发明人： Bipul Das , Ajay Narayanan , Pratik Kamleshbhai Shah
IPC分类号： A61B6/00
CPC分类号： A61B6/03 , A61B6/482 , A61B6/5235
摘要： A method, system and apparatus for filtering multi-energy images using spectral filtering technique is described. In one embodiment, the method includes obtaining a first image of an anatomical object corresponding to a first radiation energy. In addition, the method includes obtaining at least one additional image, herein called a second image of the anatomical object corresponding to at least one second radiation energy. The at least one second radiation energy is distinct from the first radiation energy. The method also includes determining joint attenuation characteristics of each tissue at the first radiation energy and at the second radiation energy or their derivatives. The method also includes selectively filtering attenuation value in a multi-energy space due to at least one tissue to generate a filtered image from a reference image. The reference image is one of the first image or the second image or their derivatives.
摘要翻译：描述了使用频谱滤波技术对多能图像进行滤波的方法，系统和装置。在一个实施例中，该方法包括获得对应于第一辐射能量的解剖对象的第一图像。此外，该方法包括获得至少一个附加图像，这里称为对应于至少一个第二辐射能量的解剖学对象的第二图像。至少一个第二辐射能与第一辐射能不同。该方法还包括在第一辐射能量和第二辐射能量或其衍生物处确定每个组织的联合衰减特性。该方法还包括由于至少一个组织选择性地过滤多能空间中的衰减值，以从参考图像生成滤波图像。参考图像是第一图像或第二图像之一或其衍生物。

5. 发明授权

US09271688B2 System and method for contrast agent estimation in X-ray imaging 有权
标题翻译： X射线成像中造影剂估计的系统和方法
公开(公告)号：US09271688B2
公开(公告)日：2016-03-01
申请号：US13433055
申请日：2012-03-28
申请人： Bipul Das , Ajay Narayanan , Pratik Shah
发明人： Bipul Das , Ajay Narayanan , Pratik Shah
IPC分类号： A61B6/00 , G06T5/50 , A61B6/03
CPC分类号： A61B6/481 , A61B6/032 , A61B6/482 , A61B6/507 , A61B6/5217 , G06T5/50 , G06T2207/10116 , G06T2207/20224 , G06T2207/30101
摘要： The disclosed embodiments relate to determining an amount of a contrast agent in an image. For example, a computer-implemented method of image processing includes generating, from a first polychromatic contrast-enhanced X-ray image obtained at a first energy and a second polychromatic contrast-enhanced X-ray image obtained at a second energy, a simulated first monochromatic contrast-enhanced X-ray image and a simulated second monochromatic contrast-enhanced X-ray image. The simulated first monochromatic contrast-enhanced X-ray image includes first regions of enhanced contrast and the simulated second monochromatic contrast-enhanced includes second regions of enhanced contrast. The method also includes isolating the first and second regions of enhanced contrast from other regions of the image, and determining an amount of the contrast agent within the first and second regions of enhanced contrast based at least on a derived partial signal attributable to the contrast agent.
摘要翻译：所公开的实施例涉及确定图像中造影剂的量。例如，计算机实现的图像处理方法包括：从在第一能量获得的第一多色对比度增强的X射线图像和以第二能量获得的第二多色对比度增强的X射线图像生成模拟的第一单色对比度增强的X射线图像和模拟的第二单色对比度增强的X射线图像。模拟的第一单色对比增强X射线图像包括增强对比度的第一区域，并且模拟的第二单色对比度增强包括增强对比度的第二区域。该方法还包括将增强的对比度的第一和第二区域与图像的其他区域隔离，以及至少基于归因于造影剂的导出部分信号来确定增强对比度的第一和第二区域内的造影剂的量。

6. 发明授权

US08855385B2 Apparatus and method for multi-energy tissue quantification 有权
标题翻译：多能组织定量的装置和方法
公开(公告)号：US08855385B2
公开(公告)日：2014-10-07
申请号：US13542964
申请日：2012-07-06
申请人： Andras Kriston , Peter Alexander John Lamb , Paulo Ricardo dos Santos Mendonca , Masayuki Kudo , Kosuke Sasaki , Souma Sengupta , Rahul Bhotika , Laszlo Rusko , Bipul Das , Scott David Wollenweber , Ferenc Kovacs
发明人： Andras Kriston , Peter Alexander John Lamb , Paulo Ricardo dos Santos Mendonca , Masayuki Kudo , Kosuke Sasaki , Souma Sengupta , Rahul Bhotika , Laszlo Rusko , Bipul Das , Scott David Wollenweber , Ferenc Kovacs
IPC分类号： G06K9/00
CPC分类号： A61B6/482 , A61B6/032 , A61B6/12 , A61B6/481 , A61B6/50 , A61B6/5217
摘要： An apparatus for multi-energy tissue quantification includes an x-ray imaging system comprises an x-ray source configured to emit a beam of x-rays toward an object to be imaged, a detector configured to receive the x-rays attenuated by the object, and a data acquisition system (DAS) operably coupled to the detector. A computer operably connected to the x-ray source and the DAS is programmed to cause the x-ray source to emit x-rays at each of a first kVp and a second kVp toward the detector, acquire x-ray data from x-rays emitted at the first and second kVp through a region of interest (ROI), and perform a first multi-material decomposition based on the acquired x-ray data. The computer is also programmed to quantify a volume fraction of a first material in the ROI based on the first multi-material decomposition and display the volume fraction of the first material to a user.
摘要翻译：一种用于多能量组织定量的装置，包括：X射线成像系统，包括被配置为向待成像物体发射X射线束的x射线源;被配置为接收被物体衰减的x射线的检测器，以及可操作地耦合到检测器的数据采集系统（DAS）。可操作地连接到X射线源和DAS的计算机被编程为使x射线源在第一kVp和第二kVp的每一个处朝向检测器发射x射线，从x射线获取x射线数据通过感兴趣区域（ROI）在第一和第二kVp处发射，并且基于所获取的x射线数据执行第一多材料分解。计算机还被编程为基于第一多材料分解来量化ROI中的第一材料的体积分数，并将第一材料的体积分数显示给用户。

7. 发明授权

US08638999B2 Methods for generating a reconstructed tree structure from medical image data 有权
标题翻译：从医学图像数据生成重建树结构的方法
公开(公告)号：US08638999B2
公开(公告)日：2014-01-28
申请号：US13448015
申请日：2012-04-16
申请人： Ziyue Xu , Fei Zhao , Roshni Rustom Bhagalia , Bipul Das
发明人： Ziyue Xu , Fei Zhao , Roshni Rustom Bhagalia , Bipul Das
IPC分类号： G06K9/00
CPC分类号： G06K9/469 , G06K2009/00932 , G06K2209/05 , G06T7/0012 , G06T7/162 , G06T7/215 , G06T2207/10081 , G06T2207/10104 , G06T2207/10116 , G06T2207/10132 , G06T2207/20076 , G06T2207/20081 , G06T2207/30101
摘要： A computer-implemented method of post-processing medical image data is provided. The method includes receiving tracked image data representative of multiple blood vessels, generating a binary tree structure for the multiple blood vessels based on a parent-child relationship between branches of the multiple blood vessels, generating a likelihood model for determining a validity of the branches of the multiple blood vessels, and generating a likelihood score for each branch based on the respective branch's compatibility with the likelihood model. The method also includes generating a reconstructed tree for the multiple blood vessels. Compatible branches are included in the reconstructed tree, while invalid branches are not included in the reconstructed tree.
摘要翻译：提供了计算机实现的后处理医学图像数据的方法。该方法包括接收代表多个血管的跟踪图像数据，基于多个血管的分支之间的亲子关系生成多个血管的二叉树结构，生成用于确定多个血管的分支的有效性的似然模型多个血管，并且基于相应分支与可能性模型的兼容性来生成每个分支的似然分数。该方法还包括为多个血管生成重建的树。重构树中包含兼容的分支，而重建树中不包括无效分支。

8. 发明申请

US20130261441A1 SYSTEM AND METHOD FOR CONTRAST AGENT ESTIMATION IN X-RAY IMAGING 有权
标题翻译： X射线成像中对比剂估计的系统和方法
公开(公告)号：US20130261441A1
公开(公告)日：2013-10-03
申请号：US13433055
申请日：2012-03-28
申请人： Bipul Das , Ajay Narayanan , Pratik Shah
发明人： Bipul Das , Ajay Narayanan , Pratik Shah
IPC分类号： A61B6/00
CPC分类号： A61B6/481 , A61B6/032 , A61B6/482 , A61B6/507 , A61B6/5217 , G06T5/50 , G06T2207/10116 , G06T2207/20224 , G06T2207/30101
摘要： The disclosed embodiments relate to determining an amount of a contrast agent in an image. For example, a computer-implemented method of image processing includes generating, from a first polychromatic contrast-enhanced X-ray image obtained at a first energy and a second polychromatic contrast-enhanced X-ray image obtained at a second energy, a simulated first monochromatic contrast-enhanced X-ray image and a simulated second monochromatic contrast-enhanced X-ray image. The simulated first monochromatic contrast-enhanced X-ray image includes first regions of enhanced contrast and the simulated second monochromatic contrast-enhanced includes second regions of enhanced contrast. The method also includes isolating the first and second regions of enhanced contrast from other regions of the image, and determining an amount of the contrast agent within the first and second regions of enhanced contrast based at least on a derived partial signal attributable to the contrast agent.
摘要翻译：所公开的实施例涉及确定图像中造影剂的量。例如，计算机实现的图像处理方法包括：从在第一能量获得的第一多色对比度增强的X射线图像和以第二能量获得的第二多色对比度增强的X射线图像生成模拟的第一单色对比度增强的X射线图像和模拟的第二单色对比度增强的X射线图像。模拟的第一单色对比增强X射线图像包括增强对比度的第一区域，并且模拟的第二单色对比度增强包括增强对比度的第二区域。该方法还包括将增强的对比度的第一和第二区域与图像的其他区域隔离，以及至少基于归因于造影剂的导出部分信号来确定增强对比度的第一和第二区域内的造影剂的量。

9. 发明申请

US20130053689A1 METHOD AND SYSTEM FOR DESIGN OF SPECTRAL FILTER TO CLASSIFY TISSUE AND MATERIAL FROM MULTI-ENERGY IMAGES 有权
标题翻译：用于设计从多能量图像分类组织和材料的光谱滤波器的方法和系统
公开(公告)号：US20130053689A1
公开(公告)日：2013-02-28
申请号：US13215634
申请日：2011-08-23
申请人： Bipul Das , Ajay Narayanan , Pratik Kamleshbhai Shah
发明人： Bipul Das , Ajay Narayanan , Pratik Kamleshbhai Shah
IPC分类号： A61B6/03
CPC分类号： A61B6/03 , A61B6/482 , A61B6/5235
摘要： A method, system and apparatus for filtering multi-energy images using spectral filtering technique is described. In one embodiment, the method includes obtaining a first image of an anatomical object corresponding to a first radiation energy. In addition, the method includes obtaining at least one additional image, herein called a second image of the anatomical object corresponding to at least one second radiation energy. The at least one second radiation energy is distinct from the first radiation energy. The method also includes determining joint attenuation characteristics of each tissue at the first radiation energy and at the second radiation energy or their derivatives. The method also includes selectively filtering attenuation value in a multi-energy space due to at least one tissue to generate a filtered image from a reference image. The reference image is one of the first image or the second image or their derivatives.
摘要翻译：描述了使用频谱滤波技术对多能图像进行滤波的方法，系统和装置。在一个实施例中，该方法包括获得对应于第一辐射能量的解剖对象的第一图像。此外，该方法包括获得至少一个附加图像，这里称为对应于至少一个第二辐射能量的解剖学对象的第二图像。至少一个第二辐射能与第一辐射能不同。该方法还包括在第一辐射能量和第二辐射能量或其衍生物处确定每个组织的联合衰减特性。该方法还包括由于至少一个组织选择性地过滤多能空间中的衰减值，以从参考图像生成滤波图像。参考图像是第一图像或第二图像之一或其衍生物。

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