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1. 发明授权

US10035103B2 Modular, portable dialysis system 有权
公开(公告)号：US10035103B2
公开(公告)日：2018-07-31
申请号：US12610032
申请日：2009-10-30
申请人： Barry Neil Fulkerson , Martin Hering , Mark F. Smith , Jan B. Zwierstra
发明人： Barry Neil Fulkerson , Martin Hering , Mark F. Smith , Jan B. Zwierstra
IPC分类号： B01D61/28 , A61M1/14
CPC分类号： B01D61/28 , A61M1/14 , A61M2205/121 , A61M2205/3569 , A61M2209/084 , B01D2313/20
摘要： The present invention is directed toward a dialysis unit that is modular and portable, with improved functionality. In one embodiment, the dialysis system comprises a top unit that is detachably affixed to a base that comprises a reservoir for fluid storage. Among numerous other features, the portable, modular dialysis system of the present invention has improved power door locking, zoned leak detection, fluid handling, and mechanical design features that enable improved modularity.

2. 发明授权

US09295772B2 Priming system and method for dialysis systems 有权
标题翻译：透析系统和方法
公开(公告)号：US09295772B2
公开(公告)日：2016-03-29
申请号：US13372202
申请日：2012-02-13
申请人： Barry Neil Fulkerson , Martin Hering , Frank Isackson
发明人： Barry Neil Fulkerson , Martin Hering , Frank Isackson
IPC分类号： A61M1/16 , A61M1/36 , A61M1/34
CPC分类号： A61M1/3643 , A61M1/16 , A61M1/1696 , A61M1/342 , A61M1/3437 , A61M1/3465 , A61M1/3644 , A61M1/3646 , A61M1/3647 , A61M1/3649 , A61M1/365 , A61M1/3652 , A61M1/3672 , A61M2205/128 , A61M2205/3324 , A61M2205/3331 , A61M2205/3368 , A61M2205/3372 , Y10T137/0491
摘要： The application is directed to an extracorporeal blood processing system capable of using dialysate to prime the system. A plastic molded compact manifold supports molded blood and dialysate fluidic pathways along with relevant sensors, valves and pumps. The compact manifold is also disposable in one embodiment and can be detachably installed in the dialysis machine. A two-way valve in the manifold is used to direct the dialysate flow through the blood circuit to prime the circuit for use in treatment.
摘要翻译：该应用针对能够使用透析液来引导系统的体外血液处理系统。塑料成型紧凑型歧管支持模制血液和透析液流通路以及相关的传感器，阀门和泵。紧凑型歧管在一个实施例中也是一次性的，并且可以可拆卸地安装在透析机中。歧管中的二通阀用于引导透析液流经血液循环以引导电路用于治疗。

3. 发明授权

US08040493B2 Thermal flow meter 有权
标题翻译：热流量计
公开(公告)号：US08040493B2
公开(公告)日：2011-10-18
申请号：US12575449
申请日：2009-10-07
申请人： Barry Neil Fulkerson , Mark F. Smith
发明人： Barry Neil Fulkerson , Mark F. Smith
IPC分类号： G01P3/36
CPC分类号： G01F1/7084 , A61M1/3663 , G01F1/667 , G01F1/6842 , G01F1/6986 , G01F1/699
摘要： A thermal flow meter for use in dialysis is described, that uses a thermal wave to generate a signal in the fluid for which the flow rate is to be measured. The phase angle of the thermal wave signal changes when traversing downstream. The phase difference between the signals received downstream, compared with a reference excitation source signal is measured, and used to determine the flow rate of the fluid.
摘要翻译：描述了用于透析的热流量计，其使用热波来在要测量流速的流体中产生信号。当横向下游时，热波信号的相位角变化。测量下游接收的信号与参考激发源信号之间的相位差，并用于确定流体的流量。

4. 发明申请

US20100116048A1 Thermal Flow Meter 有权
标题翻译：热流量计
公开(公告)号：US20100116048A1
公开(公告)日：2010-05-13
申请号：US12575449
申请日：2009-10-07
申请人： Barry Neil Fulkerson , Mark F. Smith
发明人： Barry Neil Fulkerson , Mark F. Smith
IPC分类号： G01F1/68
CPC分类号： G01F1/7084 , A61M1/3663 , G01F1/667 , G01F1/6842 , G01F1/6986 , G01F1/699
摘要： A thermal flow meter for use in dialysis is described, that uses a thermal wave to generate a signal in the fluid for which the flow rate is to be measured. The phase angle of the thermal wave signal changes when traversing downstream. The phase difference between the signals received downstream, compared with a reference excitation source signal is measured, and used to determine the flow rate of the fluid.
摘要翻译：描述了用于透析的热流量计，其使用热波来在要测量流速的流体中产生信号。当横向下游时，热波信号的相位角变化。测量下游接收的信号与参考激发源信号之间的相位差，并用于确定流体的流量。

5. 发明授权

US08535522B2 System and method for detection of disconnection in an extracorporeal blood circuit 有权
标题翻译：用于检测体外血液回路断开的系统和方法
公开(公告)号：US08535522B2
公开(公告)日：2013-09-17
申请号：US12705054
申请日：2010-02-12
申请人： Barry Neil Fulkerson , James R. Braig
发明人： Barry Neil Fulkerson , James R. Braig
IPC分类号： B01D61/32 , B01D61/28 , B01D61/30 , A61M1/14
CPC分类号： A61M1/3653 , A61M1/3639 , A61M1/3656 , A61M1/3659 , A61M2230/06
摘要： The present invention is directed to a dialysis system with a disconnection monitor for determining if a blood line connection to a patient has been disconnected. It includes a blood circuit in fluid communication with a patient and a dialysis circuit, a pressure transducer for generating a signal indicative of a pulse signal in the blood circuit, a cardiac reference signal generator for generating a signal indicative of the patient's pulse and a disconnection monitor. The disconnection monitor includes a pressure transducer data receiver for receiving the signal indicative of the pulse signal in the blood circuit, a cardiac reference signal receiver for receiving the signal indicative of the patient's pulse, and a processor for cross-correlating the signal indicative of the pulse signal in the blood circuit and the signal indicative of the patient's pulse to generate data indicative of a disconnection of the blood line connection to the patient.
摘要翻译：本发明涉及一种具有断开监视器的透析系统，用于确定与患者的血液线路连接是否已断开。它包括与患者流体连通的血液回路和透析电路，用于产生指示血液回路中脉冲信号的信号的压力传感器，用于产生指示患者脉搏和断开的信号的心脏参考信号发生器监控。断开监视器包括：压力传感器数据接收器，用于接收指示血液回路中的脉冲信号的信号;心脏参考信号接收器，用于接收指示患者脉搏的信号;以及处理器，用于将指示脉搏信号和指示患者脉搏的信号，以产生指示与患者的血液线路连接断开的数据。

6. 发明申请

US20120204968A1 Priming System and Method for Dialysis Systems 有权
标题翻译：透析系统和方法
公开(公告)号：US20120204968A1
公开(公告)日：2012-08-16
申请号：US13372202
申请日：2012-02-13
申请人： Barry Neil Fulkerson , Martin Hering , Frank Isackson
发明人： Barry Neil Fulkerson , Martin Hering , Frank Isackson
IPC分类号： F16K51/00
CPC分类号： A61M1/3643 , A61M1/16 , A61M1/1696 , A61M1/342 , A61M1/3437 , A61M1/3465 , A61M1/3644 , A61M1/3646 , A61M1/3647 , A61M1/3649 , A61M1/365 , A61M1/3652 , A61M1/3672 , A61M2205/128 , A61M2205/3324 , A61M2205/3331 , A61M2205/3368 , A61M2205/3372 , Y10T137/0491
摘要： The application is directed to an extracorporeal blood processing system capable of using dialysate to prime the system. A plastic molded compact manifold supports molded blood and dialysate fluidic pathways along with relevant sensors, valves and pumps. The compact manifold is also disposable in one embodiment and can be detachably installed in the dialysis machine. A two-way valve in the manifold is used to direct the dialysate flow through the blood circuit to prime the circuit for use in treatment.
摘要翻译：该应用针对能够使用透析液来引导系统的体外血液处理系统。塑料成型紧凑型歧管支持模制血液和透析液流通路以及相关的传感器，阀门和泵。紧凑型歧管在一个实施例中也是一次性的，并且可以可拆卸地安装在透析机中。歧管中的二通阀用于引导透析液流经血液循环以引导电路用于治疗。

7. 发明授权

US08137553B2 Priming system and method for dialysis systems 有权
标题翻译：透析系统和方法
公开(公告)号：US08137553B2
公开(公告)日：2012-03-20
申请号：US12575450
申请日：2009-10-07
申请人： Barry Neil Fulkerson , Martin Hering , Frank Isackson
发明人： Barry Neil Fulkerson , Martin Hering , Frank Isackson
IPC分类号： B01D61/30 , B01D61/32 , B01D61/28
CPC分类号： A61M1/3643 , A61M1/16 , A61M1/1696 , A61M1/342 , A61M1/3437 , A61M1/3465 , A61M1/3644 , A61M1/3646 , A61M1/3647 , A61M1/3649 , A61M1/365 , A61M1/3652 , A61M1/3672 , A61M2205/128 , A61M2205/3324 , A61M2205/3331 , A61M2205/3368 , A61M2205/3372 , Y10T137/0491
摘要： The application is directed to an extracorporeal blood processing system capable of using dialysate to prime the system. A plastic molded compact manifold supports molded blood and dialysate fluidic pathways along with relevant sensors, valves and pumps. The compact manifold is also disposable in one embodiment and can be detachably installed in the dialysis machine. A two-way valve in the manifold is used to direct the dialysate flow through the blood circuit to prime the circuit for use in treatment.
摘要翻译：该应用针对能够使用透析液来引导系统的体外血液处理系统。塑料成型紧凑型歧管支持模制血液和透析液流通路以及相关的传感器，阀门和泵。紧凑型歧管在一个实施例中也是一次性的，并且可以可拆卸地安装在透析机中。歧管中的二通阀用于引导透析液流经血液循环以引导电路用于治疗。

8. 发明授权

US08771511B2 Disposable apparatus and kit for conducting dialysis 有权
标题翻译：用于进行透析的一次性装置和试剂盒
公开(公告)号：US08771511B2
公开(公告)日：2014-07-08
申请号：US13346714
申请日：2012-01-09
申请人： Thomas Patrick Robinson , Charles E. Clemens , David Jacob Mishelevich , James Roswell Braig , Barry Neil Fulkerson , Daniele Ghidoli , Russell Thomas Joseph
发明人： Thomas Patrick Robinson , Charles E. Clemens , David Jacob Mishelevich , James Roswell Braig , Barry Neil Fulkerson , Daniele Ghidoli , Russell Thomas Joseph
IPC分类号： B01D61/30 , B01D61/28 , A61M1/16 , A61M1/28 , A61M1/34
CPC分类号： A61M1/3417 , A61M1/16 , A61M1/1601 , A61M1/1621 , A61M1/1696 , A61M1/28 , A61M1/34 , A61M1/3403 , A61M1/367 , A61M39/08 , A61M2202/0413 , A61M2205/12 , A61M2205/126 , A61M2205/128 , A61M2205/3313 , A61M2205/3317 , A61M2205/3324 , A61M2205/3331 , A61M2205/3334 , A61M2205/3368 , A61M2205/75 , A61M2209/00 , Y10T137/85938
摘要： An extracorporeal blood processing system comprises a plastic molded compact manifold that supports a plurality of molded blood and dialysate fluidic pathways along with a plurality of relevant sensors, valves and pumps. A disposable dialyzer is connected to the molded manifold to complete the blood circuit of the system. The compact manifold is also disposable in one embodiment and can be detachably installed in the dialysis machine.
摘要翻译：体外血液处理系统包括塑料模制紧凑型歧管，其与多个相关传感器，阀和泵一起支撑多个模制血液和透析液流动路径。一次性透析器连接到模制歧管，以完成系统的血液回路。紧凑型歧管在一个实施例中也是一次性的，并且可以可拆卸地安装在透析机中。

9. 发明授权

US08597505B2 Portable dialysis machine 有权
标题翻译：便携式透析机
公开(公告)号：US08597505B2
公开(公告)日：2013-12-03
申请号：US13023490
申请日：2011-02-08
申请人： Barry Neil Fulkerson , Russell Thomas Joseph , James Roswell Braig , Victor Gura , David J. Mishelevich , Thomas Robinson , Charles Clemens , Milan Trcka , Clark Berg Foster , Daniele Ghidoli , Martin Hering , Frank Isackson , Jan Brian Zwierstra , Mark Forrest Smith
发明人： Barry Neil Fulkerson , Russell Thomas Joseph , James Roswell Braig , Victor Gura , David J. Mishelevich , Thomas Robinson , Charles Clemens , Milan Trcka , Clark Berg Foster , Daniele Ghidoli , Martin Hering , Frank Isackson , Jan Brian Zwierstra , Mark Forrest Smith
IPC分类号： B01D61/30 , B01D61/32 , B01D61/34 , A61M1/16 , A61M1/34
CPC分类号： A61M1/3413 , A61M1/1609 , A61M1/1645 , A61M1/166 , A61M1/1692 , A61M1/1696 , A61M1/3406 , A61M1/3626 , A61M1/3639 , A61M1/3641 , A61M1/3646 , A61M1/3656 , A61M1/3672 , A61M1/369 , A61M2205/10 , A61M2205/126 , A61M2205/13 , A61M2205/14 , A61M2205/15 , A61M2205/18 , A61M2205/3306 , A61M2205/3317 , A61M2205/3334 , A61M2205/3368 , A61M2205/3375 , A61M2205/3393 , A61M2205/3553 , A61M2205/3584 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2205/584 , A61M2205/6072 , A61M2209/084 , B01D61/18 , B01D61/30 , B01D2313/10 , B01D2313/105 , B01D2313/12 , B01D2313/125 , B01D2313/243
摘要： The specification discloses a portable dialysis machine having a detachable controller unit and base unit. The controller unit includes a door having an interior face, a housing with a panel where the housing and panel define a recessed region configured to receive the interior face of the door, and a manifold receiver fixedly attached to the panel. The base unit has a planar surface for receiving a container of fluid, a scale integrated with the planar surface, a heater in thermal communication with the planar surface, and a sodium sensor in electromagnetic communication with the planar surface. Embodiments of the disclosed portable dialysis system have improved structural and functional features, including improved modularity, ease of use, and safety features.
摘要翻译：本说明书公开了一种具有可拆卸控制器单元和基座单元的便携式透析机。控制器单元包括具有内表面的门，具有面板的壳体，其中壳体和面板限定了构造成容纳门的内表面的凹陷区域，以及固定地连接到面板的歧管接收器。基座单元具有用于接收流体容器的平坦表面，与平坦表面集成的刻度，与平坦表面热连通的加热器和与平坦表面电磁连通的钠传感器。所公开的便携式透析系统的实施例具有改进的结构和功能特征，包括改进的模块性，易用性和安全特征。

10. 发明授权

US08475399B2 Methods and systems for measuring and verifying additives for use in a dialysis machine 有权
标题翻译：用于测量和验证用于透析机中的添加剂的方法和系统
公开(公告)号：US08475399B2
公开(公告)日：2013-07-02
申请号：US12713447
申请日：2010-02-26
申请人： Barry Neil Fulkerson
发明人： Barry Neil Fulkerson
IPC分类号： A61M37/00
CPC分类号： A61M1/342 , A61M1/16 , A61M1/1607 , A61M2205/3317 , A61M2205/3324 , A61M2205/3393 , A61M2205/502 , A61M2205/52 , A61M2205/6072
摘要： The present application discloses a portable dialysis system for conducting a dialysis treatment. The portable dialysis system has a controller unit that includes a display, a scale, a bar code reader, and a memory storing a plurality of programmatic instructions. Upon execution, the instructions generate a first graphical user interface, a second graphical user interface, and a third graphical user interface for presentation on the display. The first graphical user interface displays each additive required for use in the dialysis treatment. The second graphical user interface prompts a user to submit additives to scanning using the bar code scanner. The third graphical user interface prompts a user to submit additives to measurement using the scale.
摘要翻译：本申请公开了一种用于进行透析治疗的便携式透析系统。便携式透析系统具有包括显示器，秤，条形码读取器和存储多个编程指令的存储器的控制器单元。在执行时，指令生成第一图形用户界面，第二图形用户界面和用于在显示器上呈现的第三图形用户界面。第一个图形用户界面显示用于透析治疗所需的每种添加剂。第二个图形用户界面提示用户使用条码扫描器提交添加剂进行扫描。第三个图形用户界面提示用户使用刻度提交添加剂进行测量。

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