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1. 发明申请

WO2004101067A3 CAPTURE MANAGEMENT IMPROVEMENTS 审中-公开
标题翻译：捕获管理改进
公开(公告)号：WO2004101067A3
公开(公告)日：2005-03-31
申请号：PCT/US2004014481
申请日：2004-05-07
申请人： MEDTRONIC INC , RUETER JOHN C , MANRODT CHRISTOPHER M , BUSACKER JAMES W , SHELDON TODD J
发明人： RUETER JOHN C , MANRODT CHRISTOPHER M , BUSACKER JAMES W , SHELDON TODD J
IPC分类号： A61N1/08 , A61N1/368 , A61N1/37
CPC分类号： A61N1/368 , A61N1/371 , A61N1/3712 , A61N1/3714 , A61N2001/083
摘要： A capture detection algorithm detects and distinguishes atrial capture . Atrial chamber reset (ACR) and AV conduction (AVC) algorithms are implemented to measure an atrial pacing threshold The data that is used to choose between ACR and AVC methods is used to determine the progression of the patient's disease state. Some of the significant aspects of the invention include enablement of accurate threshold measurements, including calculation of stability criteria, precise interval measurements and the use of reference interval to determine capture and loss of capture.
摘要翻译：捕获检测算法检测并区分心房捕获。实施房室复位（ACR）和AV传导（AVC）算法来测量心房起搏阈值用于在ACR和AVC方法之间选择的数据用于确定患者疾病状态的进展。本发明的一些重要方面包括启用准确的阈值测量，包括稳定性标准的计算，精确的间隔测量以及参考间隔的使用以确定捕获和捕获的丢失。

2. 发明申请

WO2008089375A1 METHODS FOR ESTIMATING REMAINING BATTERY SERVICE LIFE IN AN IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：用于估计可移植医疗设备中的电池服务寿命的方法
公开(公告)号：WO2008089375A1
公开(公告)日：2008-07-24
申请号：PCT/US2008/051381
申请日：2008-01-18
申请人： MEDTRONIC, INC , SCHMIDT, Craig L. , WAHLSTRAND, John D. , CRESPI, Ann M. , YOUNKER, Gregory A. , BUSACKER, James W.
发明人： SCHMIDT, Craig L. , WAHLSTRAND, John D. , CRESPI, Ann M. , YOUNKER, Gregory A. , BUSACKER, James W.
IPC分类号： A61N1/37
CPC分类号： A61N1/3708
摘要： Methods for estimating a remaining service life of an implantable medical device (IMD) battery employ calculations using a characteristic discharge model of the battery; the calculations require measurements of battery voltage and time. Systems employing the methods may include an external device coupled to the IMD, for example, via a telemetry communications link, wherein a first portion of a computer readable medium included in the IMD is programmed to provide instructions for the measurement, or tracking, of time and the measurement of battery voltage, and a second portion of the computer readable medium included in the external device is programmed to provide instructions for carrying out the calculations when the voltage and time data is transferred via telemetry from the IMD to the external device.
摘要翻译：用于估计可植入医疗装置（IMD）电池的剩余使用寿命的方法使用电池的特征放电模型进行计算; 计算需要测量电池电压和时间。采用该方法的系统可以包括例如经由遥测通信链路耦合到IMD的外部设备，其中包括在IMD中的计算机可读介质的第一部分被编程为提供用于测量或跟踪时间的指令并且电池电压的测量以及外部设备中包括的计算机可读介质的第二部分被编程为当电压和时间数据经由遥测从IMD传输到外部设备时提供用于执行计算的指令。

3. 发明申请

WO2004101067A2 CAPTURE MANAGEMENT IMPROVEMENTS 审中-公开
标题翻译：捕获管理改进
公开(公告)号：WO2004101067A2
公开(公告)日：2004-11-25
申请号：PCT/US2004/014481
申请日：2004-05-07
申请人： MEDTRONIC, INC. , RUETER, John, C. , MANRODT, Christopher, M. , BUSACKER, James, W. , SHELDON, Todd, J.
发明人： RUETER, John, C. , MANRODT, Christopher, M. , BUSACKER, James, W. , SHELDON, Todd, J.
IPC分类号： A61N1/37
CPC分类号： A61N1/368 , A61N1/371 , A61N1/3712 , A61N1/3714 , A61N2001/083
摘要： A capture detection algorithm detects and distinguishes atrial capture . Atrial chamber reset (ACR) and AV conduction (AVC) algorithms are implemented to measure an atrial pacing threshold The data that is used to choose between ACR and AVC methods is used to determine the progression of the patient's disease state. Some of the significant aspects of the invention include enablement of accurate threshold measurements, including calculation of stability criteria, precise interval measurements and the use of reference interval to determine capture and loss of capture.
摘要翻译：捕获检测算法检测并区分心房捕获。实施房室复位（ACR）和AV传导（AVC）算法来测量心房起搏阈值用于在ACR和AVC方法之间选择的数据用于确定患者疾病状态的进展。本发明的一些重要方面包括启用准确的阈值测量，包括稳定性标准的计算，精确的间隔测量以及参考间隔的使用以确定捕获和捕获的丢失。

4. 发明申请

WO2009091407A2 ESTIMATING REMAINING BATTERY SERVICE LIFE IN AN IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：估计在可移植医疗设备中的电池服务寿命
公开(公告)号：WO2009091407A2
公开(公告)日：2009-07-23
申请号：PCT/US2008/051445
申请日：2008-01-18
申请人： MEDTRONIC, INC , SCHMIDT, Craig L. , WAHLSTRAND, John D. , CRESPI, Ann M. , YOUNKER, Gregory A. , BUSACKER, James W.
发明人： SCHMIDT, Craig L. , WAHLSTRAND, John D. , CRESPI, Ann M. , YOUNKER, Gregory A. , BUSACKER, James W.
IPC分类号： G01R31/36 , A61N1/36 , A61N1/372
CPC分类号： A61N1/37252 , A61N1/3708 , G01R31/3651 , G01R31/3679

5. 发明申请

WO2008042733A3 REPLACEMENT INDICATOR TIMER FOR IMPLANTABLE MEDICAL DEVICES 审中-公开
标题翻译：用于植入式医疗设备的替换指示器定时器
公开(公告)号：WO2008042733A3
公开(公告)日：2008-06-26
申请号：PCT/US2007079805
申请日：2007-09-28
申请人： MEDTRONIC INC , BETZOLD ROBERT A , BUSACKER JAMES W
发明人： BETZOLD ROBERT A , BUSACKER JAMES W
IPC分类号： A61N1/00 , A61N1/37
CPC分类号： A61N1/3708
摘要： A system and method is provided for reliably indicating that an implantable medical device is in need of replacement. An implantable medical device includes a battery and a replacement indicator timer. The battery provides power to the implantable medical device. The replacement indicator timer counts a replacement time period to a determined replacement date for the implantable medical device. The replacement indicator timer starts the counting when an operational characteristic of the battery reaches a selected value.
摘要翻译：提供了用于可靠地指示可植入医疗装置需要更换的系统和方法。可植入医疗装置包括电池和替换指示器计时器。电池为植入式医疗设备提供电力。替换指示器计时器将替换时间段计数为植入式医疗设备的确定替换日期。当电池的操作特性达到选定值时，更换指示器计时器开始计数。

6. 发明申请

WO2008042733A2 REPLACEMENT INDICATOR TIMER FOR IMPLANTABLE MEDICAL DEVICES 审中-公开
标题翻译：可移植医疗器械替换指示器定时器
公开(公告)号：WO2008042733A2
公开(公告)日：2008-04-10
申请号：PCT/US2007/079805
申请日：2007-09-28
申请人： MEDTRONIC, INC. , BETZOLD, Robert, A. , BUSACKER, James, W.
发明人： BETZOLD, Robert, A. , BUSACKER, James, W.
IPC分类号： A61N1/00 , A61N1/37
CPC分类号： A61N1/3708
摘要： A system and method is provided for reliably indicating that an implantable medical device is in need of replacement. An implantable medical device includes a battery and a replacement indicator timer. The battery provides power to the implantable medical device. The replacement indicator timer counts a replacement time period to a determined replacement date for the implantable medical device. The replacement indicator timer starts the counting when an operational characteristic of the battery reaches a selected value.
摘要翻译：提供了可靠地指示可植入医疗装置需要更换的系统和方法。可植入医疗装置包括电池和替换指示器计时器。电池为可植入医疗设备提供电力。替换指示器定时器将替换时间段计数到确定的可植入医疗装置的替换日期。当电池的操作特性达到选定值时，替换指示器定时器开始计数。

7. 发明申请

WO2007076177A1 METHOD OF CONTINUOUS CAPTURE VERIFICATION IN CARDIAC RESYNCHRONIZATION DEVICES 审中-公开
标题翻译：心脏再生装置中连续检测验证方法
公开(公告)号：WO2007076177A1
公开(公告)日：2007-07-05
申请号：PCT/US2006/060812
申请日：2006-11-12
申请人： MEDTRONIC, INC. , BUSACKER, James W. , SHELDON, Todd J.
发明人： BUSACKER, James W. , SHELDON, Todd J.
IPC分类号： A61N1/00
CPC分类号： A61N1/3627 , A61N1/3684 , A61N1/371
摘要： In bi-ventricular pacing devices (including CRT devices) analysis of myocardial electrogram signals in one ventricle (e.g., a left ventricle, or "LV") can be used to infer capture or loss-of-capture (LOC) of an earlier stimulus pulse in the same ventricle, on a continuous (every pacing cycle), triggered, aperiodic and/or periodic basis. Rather than using an evoked-response principle as has been the basis of capture detection in prior art and other systems, a principle employed via the present invention uses evidence of inter-ventricular conduction (i.e., from the opposite chamber) and/or atrio-ventricular conduction as evidence of LOC, since a non-capturing pacing stimulus provided to a first chamber will allow the myocardial tissue of the first chamber to remain non-refractory and thus inter-ventricular and atrio-ventricular wavefront propagation and conduction can commence and be detected thereby revealing whether LOC has occurred.
摘要翻译：在双心室起搏装置（包括CRT装置）中，可以使用一个心室（例如，左心室或“LV”）分析心肌电图信号来推断早期刺激的捕获或丢失（LOC）脉冲在同一个心室，连续（每个起搏周期），触发，非周期和/或周期基础。不是使用诱发反应原理作为现有技术和其他系统中的捕获检测的基础，通过本发明采用的原理使用室间传导（即，从相对的室）和/或心室传导的证据，心室传导作为LOC的证据，因为提供给第一腔室的非捕获起搏刺激将允许第一腔室的心肌组织保持不耐受，因此可以开始心室间和心房内波前传播和传导从而揭示LOC是否发生。

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