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1. 发明授权

EP0418339B1 COMPOSITION AND METHOD FOR PREVENTION OF ADHESIONS BETWEEN BODY TISSUES 失效
标题翻译：组合物及方法，以防止身体组织之间的粘连。
公开(公告)号：EP0418339B1
公开(公告)日：1994-11-02
申请号：EP90903989.3
申请日：1990-02-21
申请人： Buckley, Peter , Lindblad, Gert
发明人： Buckley, Peter , Lindblad, Gert
IPC分类号： C08L5/00 , A61K31/715
CPC分类号： C08L5/02 , A61K31/715 , C08L2666/02
摘要： A composition for the prevention of adhesions between body tissues after surgical operation, containing dextran and hyaluronic acid. The invention further claims the use of the said components for the preparation of such a composition as well as its use as an agent for the prevention of adhesions.

2. 发明专利

GB9406768D0 Senses travel slippers 未知
公开(公告)号：GB9406768D0
公开(公告)日：1994-05-25
申请号：GB9406768
申请日：1994-04-06
申请人： BUCKLEY PETER I , TAYLOR JANE

3. 发明专利

DE69013833T2 未知
公开(公告)号：DE69013833T2
公开(公告)日：1995-06-08
申请号：DE69013833
申请日：1990-02-21
申请人： BUCKLEY PETER , LINDBLAD GERT
发明人： BUCKLEY PETER , LINDBLAD GERT
IPC分类号： C08L5/02 , C08L5/00 , A61K31/715

4. 发明专利

GB9406767D0 Senses sleep mask 未知
公开(公告)号：GB9406767D0
公开(公告)日：1994-05-25
申请号：GB9406767
申请日：1994-04-06
申请人： BUCKLEY PETER I , TAYLOR JANE

5. 发明专利

DK0418339T3 未知
公开(公告)号：DK0418339T3
公开(公告)日：1995-04-03
申请号：DK90903989
申请日：1990-02-21
申请人： BUCKLEY PETER , LINDBLAD GERT
发明人： BUCKLEY PETER , LINDBLAD GERT
IPC分类号： C08L5/02 , C08L5/00 , A61K31/715

6. 发明申请

WO2015089073A3 COMPOSITIONS AND METHODS FOR PHAGOCYTE DELIVERY OF ANTI-STAPHYLOCOCCAL AGENTS 审中-公开
标题翻译：抗啮齿动物药剂的组合物和方法
公开(公告)号：WO2015089073A3
公开(公告)日：2015-10-08
申请号：PCT/US2014069347
申请日：2014-12-09
申请人： UNIV NEW YORK , JANSSEN BIOTECH INC , TORRES VICTOR J , BREZSKI RANDALL J , LYNCH ANTHONY , STROHL WILLIAM , WHITAKER BRIAN , CHIU MARK , BUCKLEY PETER T , SORING KERI , KINDER MICHELLE
发明人： TORRES VICTOR J , BREZSKI RANDALL J , LYNCH ANTHONY , STROHL WILLIAM , WHITAKER BRIAN , CHIU MARK , BUCKLEY PETER T , SORING KERI , KINDER MICHELLE
IPC分类号： C07K16/12 , G01N33/569
CPC分类号： C07K16/1271 , C07K14/78 , C07K2317/30 , C07K2317/31 , C07K2317/51 , C07K2317/515 , C07K2318/00 , C07K2319/70 , G01N33/56938 , G01N2469/10
摘要： The present application generally relates to multi-specific molecules that bind to multiple bacterial virulence factors, methods for producing these binding molecules, and the use of these binding molecules to treat bacterial infections. In particular, the binding molecules comprise at least two binding domains, preferably an antibody or antibody fragment and an alternative scaffold. The first binding domain is capable of binding to a glycosylated staphylococcal surface protein, preferably an SDR- containing protein. The second binding domain is capable of binding to a staphylococcal leukotoxin, preferably LukAB, LukD or LukE. These multi-specific binding compounds have killing activity against staphylococci and, thus, can be used in the treatment and/or amelioration of a Staphylococcus infection, including methicillin-resistant Staphylococcus aureus.
摘要翻译：本申请一般涉及结合多种细菌毒力因子的多特异性分子，产生这些结合分子的方法以及使用这些结合分子来治疗细菌感染。特别地，结合分子包含至少两个结合结构域，优选抗体或抗体片段和替代支架。第一结合结构域能够结合糖基化葡萄球菌表面蛋白，优选含有SDR的蛋白。第二结合结构域能够结合葡萄球菌白细胞毒素，优选LukAB，LukD或LukE。这些多特异性结合化合物对葡萄球菌具有杀伤活性，因此可用于治疗和/或改善葡萄球菌感染，包括耐甲氧西林金黄色葡萄球菌。

7. 发明申请

WO1990010031A1 COMPOSITION AND METHOD FOR PREVENTION OF ADHESIONS BETWEEN BODY TISSUES 审中-公开
标题翻译：用于预防身体组织之间粘合的组合物和方法
公开(公告)号：WO1990010031A1
公开(公告)日：1990-09-07
申请号：PCT/SE1990000117
申请日：1990-02-21
申请人： PHARMACIA AB , LINDBLAD, Gert , BUCKLEY, Peter
发明人： PHARMACIA AB
IPC分类号： C08L05/00
CPC分类号： C08L5/02 , A61K31/715 , C08L2666/02
摘要： A composition for the prevention of adhesions between body tissues after surgical operation, containing dextran and hyaluronic acid. The invention further claims the use of the said components for the preparation of such a composition as well as its use as an agent for the prevention of adhesions.
摘要翻译：用于预防外科手术后体内组织粘连的组合物，含有葡聚糖和透明质酸。本发明还要求所述组分用于制备这种组合物的用途以及其作为预防粘连剂的用途。

8. 发明申请

WO1996008034A1 MASS SPECTROMETER SYSTEM AND METHOD USING SIMULTANEOUS MODE DETECTOR AND SIGNAL REGION FLAGS 审中-公开
标题翻译：质谱仪系统和方法同时使用模式检测器和信号区域标志
公开(公告)号：WO1996008034A1
公开(公告)日：1996-03-14
申请号：PCT/CA1995000506
申请日：1995-09-06
申请人： MDS HEALTH GROUP LIMITED , BUCKLEY, Peter , COUSINS, Lisa , DAYNES, Todd , GRETCHEV, Val , HIRASAWA, Drake , LEITH, Graham
发明人： MDS HEALTH GROUP LIMITED
IPC分类号： H01J49/02
CPC分类号： H01J49/025 , H01J43/30 , H01J49/022 , H01J49/105
摘要： A mass analyzer system uses a simultaneous mode electron multiplier detector which outputs both a pulse count and an analog signal. Depending on the ion flux intensity, the signals define a pulse count only region in which the pulse count only signal is valid, an overlap region in which both the pulse count and analog signals are valid, an analog signal only region in which only the analog signal is valid, and a neither analog nor pulse region in which neither signal is valid. The system produces a separate flag for each region. When a mass spectrum is scanned, for each dwell the pulse count and analog data are recorded together with their associated flag and are placed in memory. The signals, with the flag, can then be used to produce a mass spectrum using the pulse count only signal, the analog only signal, or both. In addition numeric displays can be produced for each peak or a variety of peaks, using the pulse count only signal, the analog signal, or both, together with a display of the flag or flags which have been set at the peak being displayed.
摘要翻译：质量分析器系统使用输出脉冲计数和模拟信号的同时模式电子倍增器检测器。根据离子通量强度，这些信号仅限于仅脉冲计数信号有效的脉冲计数区域，脉冲计数和模拟信号都有效的重叠区域，仅模拟信号区域信号有效，既不是两个信号都无效的模拟和脉冲区域。系统为每个区域生成一个单独的标志。当扫描质谱时，对于每个驻留，脉冲计数和模拟数据与其相关联的标志一起记录并放置在存储器中。然后，使用标志的信号可以用于使用仅脉冲计数信号，仅模拟信号或两者来产生质谱。此外，可以使用仅脉冲计数信号，模拟信号或两者来为每个峰值或各种峰值产生数字显示，以及在显示峰值时设置的标志或标志的显示。

9. 发明申请

WO2015089073A2 COMPOSITIONS AND METHODS FOR PHAGOCYTE DELIVERY OF ANTI-STAPHYLOCOCCAL AGENTS 审中-公开
标题翻译：抗血小板药物的药物递送的组合物和方法
公开(公告)号：WO2015089073A2
公开(公告)日：2015-06-18
申请号：PCT/US2014/069347
申请日：2014-12-09
申请人： NEW YORK UNIVERSITY , JANSSEN BIOTECH, INC. , TORRES, Victor, J. , BREZSKI, Randall, J. , LYNCH, Anthony , STROHL, William , WHITAKER, Brian , CHIU, Mark , BUCKLEY, Peter, T. , SORING, Keri , KINDER, Michelle
发明人： TORRES, Victor, J. , BREZSKI, Randall, J. , LYNCH, Anthony , STROHL, William , WHITAKER, Brian , CHIU, Mark , BUCKLEY, Peter, T. , SORING, Keri , KINDER, Michelle
IPC分类号： C07K16/12 , G01N33/569
CPC分类号： C07K16/1271 , C07K14/78 , C07K2317/30 , C07K2317/31 , C07K2317/51 , C07K2317/515 , C07K2318/00 , C07K2319/70 , G01N33/56938 , G01N2469/10
摘要： The present application generally relates to multi-specific molecules that bind to multiple bacterial virulence factors, methods for producing these binding molecules, and the use of these binding molecules to treat bacterial infections. In particular, the binding molecules comprise at least two binding domains, preferably an antibody or antibody fragment and an alternative scaffold. The first binding domain is capable of binding to a glycosylated staphylococcal surface protein, preferably an SDR- containing protein. The second binding domain is capable of binding to a staphylococcal leukotoxin, preferably LukAB, LukD or LukE. These multi-specific binding compounds have killing activity against staphylococci and, thus, can be used in the treatment and/or amelioration of a Staphylococcus infection, including methicillin-resistant Staphylococcus aureus .
摘要翻译：本申请通常涉及结合多种细菌毒力因子的多特异性分子，用于产生这些结合分子的方法，以及这些结合分子用于治疗细菌感染的用途。特别地，结合分子包含至少两个结合结构域，优选抗体或抗体片段和替代性支架。第一结合结构域能够结合糖基化的葡萄球菌表面蛋白，优选含有SDR的蛋白质。第二结合结构域能够结合葡萄球菌白血病，优选LukAB，LukD或LukE。这些多特异性结合化合物对葡萄球菌具有杀伤活性，因此可用于治疗和/或改善葡萄球菌感染，包括耐甲氧西林金黄色葡萄球菌。

10. 发明申请

WO2011037912A1 COMPOSITIONS AND METHODS FOR INDUCING OR ENHANCING CONNECTIVE TISSUE REPAIR 审中-公开
标题翻译：用于诱导或增强连接组织修复的组合物和方法
公开(公告)号：WO2011037912A1
公开(公告)日：2011-03-31
申请号：PCT/US2010/049640
申请日：2010-09-21
申请人： GLENPHARMA AB , BUCKLEY, Peter, Byron , MESSMER, Konrad , PHILLIPS, Mark, William
发明人： BUCKLEY, Peter, Byron , MESSMER, Konrad , PHILLIPS, Mark, William
IPC分类号： A01N43/04 , A61K31/715
CPC分类号： A61K31/728 , A61K9/0019 , A61K9/08 , A61K31/7016 , A61K31/715 , A61K31/721 , A61K45/06 , A61K2300/00
摘要： A composition capable of attenuating platelet hyperactivation and associated methods for administering the same to a subject, the composition comprising an aqueous solution containing from about 0.1% to about 7.0% by weight of a glycosaminoglycan and from about 1.0% to about 32% by weight of a neutral polysaccharide.
摘要翻译：一种能够减弱血小板过度活化的组合物及其与受试者的相关方法，该组合物包含含有约0.1％至约7.0％重量的糖胺聚糖和约1.0％至约32％重量的糖胺聚糖中性多糖。

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