会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 1. 发明申请
    • PROTEIN COMPLEXES AND SCREENING METHODS
    • 蛋白复合物和筛选方法
    • WO2010000374A1
    • 2010-01-07
    • PCT/EP2009/004181
    • 2009-06-10
    • BIOCANT- ASSOCIAÇÃO DE TRANSFERÊNCIA DE TECNOLOGIAVIRGINIA COMMONWEALTH UNIVERSITY INTELLECTUAL PROPERTY FOUNDATIONVALENTE, André Xavier de Carvalho NegrãoGAO, YuanBUCK, Gregory, A.ROBERTS, Seth
    • VALENTE, André Xavier de Carvalho NegrãoGAO, YuanBUCK, Gregory, A.
    • C07K14/47C07K14/395A61P27/02
    • C07K14/395C07K14/47
    • The application concerns an isolated protein complex comprising polypeptide components: (i) UTP20 HUMAN or a fragment, variant or homologue thereof; (ii) PWP2 HUMAN or a fragment, variant or homologue thereof; (iii) WDR46_HUMAN or a fragment, variant or homologue thereof; (iv) UTP18 HUMAN or a fragment, variant or homologue thereof; (v) MPPIO HUMAN or a fragment, variant or homologue thereof; (vi) WDR3_HUMAN or a fragment, variant or homologue thereof; (vii) TBL3 HUMAN or a fragment, variant or homologue thereof; (viii) WDR36_HUMAN or a fragment, variant or homologue thereof; and (ix) N0C4L HUMAN or a fragment, variant or homologue thereof. The application further concerns a method of identifying an agent that modulates the amount, function, activity, composition and/or formation of said protein complex; a method for the prevention or treatment of an eye disorder comprising administering to a subject in need thereof a suitable quantity of an agent that modulates the amount, function, activity, composition and/or formation of said protein complex; and a method of assessing whether a subject has or is likely to develop an eye disorder comprising determining whether the subject has an altered amount, function, activity, composition and/or formation of a protein complex.
    • 该应用涉及包含多肽组分的分离的蛋白质复合物:(i)UTP20Human或其片段,变体或同源物; (ii)PWP2人类或其片段,变体或同源物; (iii)WDR46_HUMAN或其片段,变体或同源物; (iv)UTP18人类或其片段,变体或同源物; (v)MPPIO HUMAN或其片段,变体或同源物; (vi)WDR3_HUMAN或其片段,变体或同源物; (vii)TBL3人类或其片段,变体或同源物; (viii)WDR36_HUMAN或其片段,变体或同源物; 和(ix)N0C4L HUMAN或其片段,变体或同源物。 本申请还涉及鉴定调节所述蛋白质复合物的量,功能,活性,组成和/或形成的试剂的方法; 一种用于预防或治疗眼睛疾病的方法,包括向有需要的受试者施用适量的调节所述蛋白质复合物的量,功能,活性,组成和/或形成的试剂; 以及评估受试者是否具有或可能发展眼病的方法,包括确定受试者是否具有改变的蛋白质复合物的量,功能,活性,组成和/或形成。
    • 3. 发明申请
    • PROTEIN COMPLEXES AND SCREENING METHODS
    • 蛋白复合物和筛选方法
    • WO2010000374A8
    • 2011-01-20
    • PCT/EP2009004181
    • 2009-06-10
    • BIOCANT ASSOCIACAO DE TRANSFERENCIA DE TECNOLOGIAUNIV VIRGINIA COMMONWEALTHVALENTE ANDRE XAVIER DE CARVALHO NEGRAOGAO YUANBUCK GREGORY AROBERTS SETH
    • VALENTE ANDRE XAVIER DE CARVALHO NEGRAOGAO YUANBUCK GREGORY AROBERTS SETH
    • C07K14/47A61P27/02C07K14/395
    • C07K14/395C07K14/47
    • The application concerns an isolated protein complex comprising polypeptide components: (i) UTP20 HUMAN or a fragment, variant or homologue thereof; (ii) PWP2 HUMAN or a fragment, variant or homologue thereof; (iii) WDR46_HUMAN or a fragment, variant or homologue thereof; (iv) UTP18 HUMAN or a fragment, variant or homologue thereof; (v) MPPIO HUMAN or a fragment, variant or homologue thereof; (vi) WDR3_HUMAN or a fragment, variant or homologue thereof; (vii) TBL3 HUMAN or a fragment, variant or homologue thereof; (viii) WDR36_HUMAN or a fragment, variant or homologue thereof; and (ix) N0C4L HUMAN or a fragment, variant or homologue thereof. The application further concerns a method of identifying an agent that modulates the amount, function, activity, composition and/or formation of said protein complex; a method for the prevention or treatment of an eye disorder comprising administering to a subject in need thereof a suitable quantity of an agent that modulates the amount, function, activity, composition and/or formation of said protein complex; and a method of assessing whether a subject has or is likely to develop an eye disorder comprising determining whether the subject has an altered amount, function, activity, composition and/or formation of a protein complex.
    • 该应用涉及包含多肽组分的分离的蛋白质复合物:(i)UTP20Human或其片段,变体或同源物; (ii)PWP2人类或其片段,变体或同源物; (iii)WDR46_HUMAN或其片段,变体或同源物; (iv)UTP18人类或其片段,变体或同源物; (v)MPPIO HUMAN或其片段,变体或同源物; (vi)WDR3_HUMAN或其片段,变体或同源物; (vii)TBL3人类或其片段,变体或同源物; (viii)WDR36_HUMAN或其片段,变体或同源物; 和(ix)N0C4L HUMAN或其片段,变体或同源物。 本申请还涉及鉴定调节所述蛋白质复合物的量,功能,活性,组成和/或形成的试剂的方法; 一种用于预防或治疗眼睛疾病的方法,包括向有需要的受试者施用适量的调节所述蛋白质复合物的量,功能,活性,组成和/或形成的试剂; 以及评估受试者是否具有或可能发展眼病的方法,包括确定受试者是否具有改变的蛋白质复合物的量,功能,活性,组成和/或形成。