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    • 1. 发明专利
    • COMPOSITE IMAGE AND ASSOCIATED GAME
    • GB2431117A
    • 2007-04-18
    • GB0520799
    • 2005-10-13
    • CORKE BRYANBRYANT JASON
    • CORKE BRYANBRYANT JASON
    • A63F13/00G07F17/32
    • An image is described being a composite formed of a view 36 and a superimposed structure 34, the structure being integrated into the view so as to form a part thereof, and comprising a representation of an assemblage of currency, e.g. coins. Generally, not all the currency will be visible. The image can be in physical form, i.e. printed, or it can be in a stored digital form for display through suitable means, such as a computer monitor. The view can be a photograph of a geographical area, such as a landscape or cityscape. It is preferably a well-known view but need not necessarily be so. The structure can form part of the view either by (for example) replacing a part of the view, or by creating a new element within the view that is in keeping with the remainder, or the like. The currency can be stacked in a shape suited to the photograph. For example, in a cityscape the currency can be stacked so as to resemble a tower block. Likewise, in a landscape the currency can be stacked so as to resemble geomorphological feature such as a mountain, ridge or headland. The image may be used in a game where players are invited to guess the number of coins or the value of the coins used to form the image.
    • 4. 发明申请
    • COMPENSATOR FOR MULTIPLE SURFACE IMAGING
    • 用于多个表面成像的补偿器
    • WO2009137435A1
    • 2009-11-12
    • PCT/US2009/042778
    • 2009-05-05
    • ILLUMINA, INC.FENG, WenyiBRYANT, JasonBUERMANN, Dale
    • FENG, WenyiBRYANT, JasonBUERMANN, Dale
    • G01N21/05G01N21/64G02B21/00
    • C12Q1/6874C12Q1/6825C12Q1/6869G01N21/05G01N21/6458G01N2021/0346G01N2021/6419G01N2021/6421G02B21/0024G02B2207/113
    • A system and method for imaging biological samples on multiple surfaces of a support structure are disclosed. The support structure may, for instance, be a flow cell through which a reagent fluid is allowed to flow and interact with the biological samples. Excitation radiation from at least one radiation source may be used to excite the biological samples on multiple surfaces. In this manner, fluorescent emission radiation may be generated from the biological samples and subsequently captured and detected by detection optics and at least one detector. The captured and detected fluorescent emission radiation may then be used to generate image data. This imaging of multiple surfaces may be accomplished either sequentially or simultaneously. In addition, the techniques of the present invention may be used with any type of imaging system. For instance, both epifluorescent and total internal reflection (TIR) methods may benefit from the techniques of the present invention. In addition, the biological samples imaged may be present on the surfaces of the support structure in a random special pattern and need not be at known locations in order for the imaging to be performed.
    • 公开了用于在支撑结构的多个表面上成像生物样品的系统和方法。 支撑结构例如可以是允许试剂流体流过并与生物样品相互作用的流动池。 可以使用来自至少一个辐射源的激发辐射来激发多个表面上的生物样品。 以这种方式,可以从生物样品产生荧光发射辐射,随后由检测光学器件和至少一个检测器捕获和检测。 捕获和检测到的荧光发射辐射然后可用于产生图像数据。 多个表面的这种成像可以顺序地或同时地完成。 此外,本发明的技术可以与任何类型的成像系统一起使用。 例如,荧光和全内反射(TIR)方法都可以受益于本发明的技术。 此外,成像的生物样品可以以随机特殊图案存在于支撑结构的表面上,并且不需要在已知位置处以便进行成像。
    • 8. 发明申请
    • FLUORESCENCE EXCITATION AND DETECTION SYSTEM AND METHOD
    • 荧光激发和检测系统及方法
    • WO2009042862A1
    • 2009-04-02
    • PCT/US2008/077850
    • 2008-09-26
    • ILLUMINA, INCPRATT, MarkBRYANT, Jason
    • PRATT, MarkBRYANT, Jason
    • G01N21/64
    • G01N21/64G01J3/4406G01N21/6428G01N21/6458G01N2021/6419G01N2021/6421G01N2021/6441G01N2021/6471
    • An excitation and detection system is provided for separately detecting different -wavelengths of emission light emitted from a sample. The system comprises an excitation assembly to excite a sample and a detection assembly to receive fluorescence emitted from the sample. The detection assembly includes a multi-band dichroic member and at least first and second detection cameras. The multi-band dichroic member has a transmission/reflection characteristic with at least two transmissive regions separated from each other along the wavelength spectrum and with at least one reflective region separated from the transmissive regions along the w avelength spectrum. The dichroic member transmits fluorescence that aligns w ith the at least two transmissive regions to the first detection camera. The dichroic member reflects fluorescence that aligns w ith the reflective region to the second detection camera. The dichroic member multiplexes the detection of fluorescent signals w ithout the use of a filter wheel in the detection assembly. The components of the detection assembly remain stationary throughout imaging of multiple colors, for example therefore allowing the use of two detectors to record images of three or more colors without the need for filter wheels or other moving components.
    • 提供激励和检测系统,用于分别检测从样品发射的发射光的不同波长。 该系统包括用于激发样品的激发组件和用于接收从样品发射的荧光的检测组件。 检测组件包括多频带分色构件和至少第一和第二检测摄像机。 多频带分色构件具有透射/反射特性,其具有沿着波长光谱彼此分离的至少两个透射区域,以及沿着长度光谱与透射区域分离的至少一个反射区域。 二向色成员透射与至少两个透射区域对准的荧光到第一检测照相机。 二向色成员将与反射区域对准的荧光反射到第二检测照相机。 二色性构件在检测组件中使用滤光轮来检测荧光信号。 检测组件的组件在多种颜色的成像中保持静止,例如因此允许使用两个检测器来记录三种或更多种颜色的图像,而不需要滤光轮或其它移动部件。