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1. 发明申请

WO2010009144A3 APPARATUS CONFIGURED TO PROVIDE A WAVELENGTH-SWEPT ELECTRO-MANGNETIC RADIATION 审中-公开
标题翻译：配置为提供波浪式扫描电磁辐射的设备
公开(公告)号：WO2010009144A3
公开(公告)日：2010-05-14
申请号：PCT/US2009050563
申请日：2009-07-14
申请人： GEN HOSPITAL CORP , GOLDBERG BRIAN , TEARNEY GUILLERMO J , BOUMA BRETT EUGENE , MOTGAHIAN-NEZAM REZA
发明人： GOLDBERG BRIAN , TEARNEY GUILLERMO J , BOUMA BRETT EUGENE , MOTGAHIAN-NEZAM REZA
IPC分类号： H01S3/10
CPC分类号： H01S5/141 , G01J3/10 , H01S3/105 , H01S5/02248 , H01S5/101 , H01S5/143
摘要： Exemplary embodiments of apparatus according to the present disclosure are provided. For example, an apparatus for providing electromagnetic radiation to a structure can be provided. In one exemplary embodiment, the apparatus can provide at least one electromagnetic radiation, and include at least one first arrangement which can be configured to generate the electromagnetic radiation(s) having at least one wavelength that varies over time. The exemplary apparatus can also include at least one second arrangement which can be configured to power the first arrangement(s) independently from an external power source. In another exemplary embodiment the apparatus can include at least one particular arrangement which is configured to generate the electromagnetic radiation(s) having at least one wavelength that varies over time. The particular arrangement(s) can include a resonant cavity that has a roundtrip optical transit time of approximately less than 0.7 nsec.
摘要翻译：提供了根据本公开的设备的示例性实施例。例如，可以提供用于向结构提供电磁辐射的装置。在一个示例性实施例中，该设备可以提供至少一个电磁辐射，并且包括至少一个第一布置，该第一布置可以被配置为生成具有随时间变化的至少一个波长的电磁辐射。示例性设备还可以包括至少一个第二布置，其可以被配置为独立于外部电源向第一布置供电。在另一个示例性实施例中，该设备可以包括至少一个特定布置，其被配置为生成具有随时间变化的至少一个波长的电磁辐射。特定布置可以包括具有大约小于0.7纳秒的往返光学传播时间的谐振腔。

2. 发明申请

WO2010009136A3 APPARATUS AND METHODS FOR COLOR ENDOSCOPY 审中-公开
标题翻译：颜色内窥镜的装置和方法
公开(公告)号：WO2010009136A3
公开(公告)日：2010-04-08
申请号：PCT/US2009050553
申请日：2009-07-14
申请人： GEN HOSPITAL CORP , TEARNEY GUILLERMO J , BOUMA BRETT EUGENE , YELIN DVIR , KANG DONGKYUN
发明人： TEARNEY GUILLERMO J , BOUMA BRETT EUGENE , YELIN DVIR , KANG DONGKYUN
IPC分类号： A61B5/05 , A61B5/07 , G05F1/00
CPC分类号： A61B1/00172 , A61B1/04 , A61B5/0062 , A61B5/0066 , A61B5/0075 , A61B5/0084 , G01J3/0218 , G01J3/0256 , G01J3/18 , G01N21/4795 , G02B23/2423 , G02B23/2469
摘要： Exemplary embodiments of apparatus and method according to the present disclosure are provided. For example, an apparatus for providing electromagnetic radiation to a structure can be provided. The exemplary apparatus can include a first arrangement having at least two wave-guides which can be configured to provide there through at least two respective electro-magnetic radiations with at least partially different wavelengths from one another. The exemplary apparatus can also include a dispersive second arrangement structured to receive the electro-magnetic radiations and forward at least two dispersed radiations associated with the respective electro-magnetic radiations to at least one section of the structure. The wave-guide(s) can be structured and/or spatially arranged with respect to the dispersive arrangement to facilitate at least partially overlap of the dispersed radiations on the structure. In addition, another arrangement can be provided which can include at least two further wave-guides which can be configured to receive the electro-magnetic radiations from the dispersive arrangement. Each of the further wave-guides can be structured and/or spatially arranged with respect to the dispersive arrangement to facilitate a receipt of a different one of the such electro-magnetic radiations as a function of wavelengths thereof.
摘要翻译：提供了根据本公开的设备和方法的示例性实施例。例如，可以提供用于向结构提供电磁辐射的装置。示例性装置可以包括具有至少两个波导的第一装置，所述至少两个波导可以被配置成通过至少两个彼此具有至少部分不同波长的相应的电磁辐射来提供它们。示例性装置还可以包括分散第二装置，其被构造为接收电磁辐射，并将与各个电磁辐射相关联的至少两个分散的辐射转发到该结构的至少一个部分。波导可以相对于分散布置被构造和/或空间布置，以促进结构上分散的辐射的至少部分重叠。此外，可以提供另外的布置，其可以包括至少两个另外的波导，其可被配置为从分散布置接收电磁辐射。每个其它波导可以相对于色散装置构造和/或空间布置，以便于接收这样的电磁辐射中不同的一个作为其波长的函数。

3. 发明申请

WO2010009144A2 APPARATUS CONFIGURED TO PROVIDE A WAVELENGTH-SWEPT ELECTRO-MANGNETIC RADIATION 审中-公开
标题翻译：配置提供波长扫描电子辐射的装置
公开(公告)号：WO2010009144A2
公开(公告)日：2010-01-21
申请号：PCT/US2009/050563
申请日：2009-07-14
申请人： THE GENERAL HOSPITAL CORPORATION , GOLDBERG, Brian , TEARNEY, Guillermo, J. , BOUMA, Brett, Eugene , MOTGAHIAN-NEZAM, Reza
发明人： GOLDBERG, Brian , TEARNEY, Guillermo, J. , BOUMA, Brett, Eugene , MOTGAHIAN-NEZAM, Reza
IPC分类号： H01S3/10
CPC分类号： H01S5/141 , G01J3/10 , H01S3/105 , H01S5/02248 , H01S5/101 , H01S5/143
摘要： Exemplary embodiments of apparatus according to the present disclosure are provided. For example, an apparatus for providing electromagnetic radiation to a structure can be provided. In one exemplary embodiment, the apparatus can provide at least one electromagnetic radiation, and include at least one first arrangement which can be configured to generate the electromagnetic radiation(s) having at least one wavelength that varies over time. The exemplary apparatus can also include at least one second arrangement which can be configured to power the first arrangement(s) independently from an external power source. In another exemplary embodiment the apparatus can include at least one particular arrangement which is configured to generate the electromagnetic radiation(s) having at least one wavelength that varies over time. The particular arrangement(s) can include a resonant cavity that has a roundtrip optical transit time of approximately less than 0.7 nsec.
摘要翻译：提供了根据本公开的设备的示例性实施例。例如，可以提供用于向结构提供电磁辐射的装置。在一个示例性实施例中，该装置可以提供至少一个电磁辐射，并且包括至少一个第一布置，其可被配置为产生具有随时间变化的至少一个波长的电磁辐射。示例性装置还可以包括至少一个第二装置，其可被配置为独立于外部电源为第一装置供电。在另一个示例性实施例中，装置可以包括至少一个特定布置，其被配置为产生具有随时间变化的至少一个波长的电磁辐射。具体布置可以包括谐振腔，其具有大约小于0.7纳秒的往返光通过时间。

4. 发明申请

WO2010009136A2 APPARATUS AND METHODS FOR COLOR ENDOSCOPY 审中-公开
标题翻译：用于彩色内窥镜的装置和方法
公开(公告)号：WO2010009136A2
公开(公告)日：2010-01-21
申请号：PCT/US2009/050553
申请日：2009-07-14
申请人： THE GENERAL HOSPITAL CORPORATION , TEARNEY, Guillermo, J. , BOUMA, Brett, Eugene , YELIN, Dvir , KANG, Dongkyun
发明人： TEARNEY, Guillermo, J. , BOUMA, Brett, Eugene , YELIN, Dvir , KANG, Dongkyun
IPC分类号： A61B5/05 , A61B5/07
CPC分类号： A61B1/00172 , A61B1/04 , A61B5/0062 , A61B5/0066 , A61B5/0075 , A61B5/0084 , G01J3/0218 , G01J3/0256 , G01J3/18 , G01N21/4795 , G02B23/2423 , G02B23/2469
摘要： Exemplary embodiments of apparatus and method according to the present disclosure are provided. For example, an apparatus for providing electromagnetic radiation to a structure can be provided. The exemplary apparatus can include a first arrangement having at least two wave-guides which can be configured to provide there through at least two respective electro-magnetic radiations with at least partially different wavelengths from one another. The exemplary apparatus can also include a dispersive second arrangement structured to receive the electro-magnetic radiations and forward at least two dispersed radiations associated with the respective electro-magnetic radiations to at least one section of the structure. The wave-guide(s) can be structured and/or spatially arranged with respect to the dispersive arrangement to facilitate at least partially overlap of the dispersed radiations on the structure. In addition, another arrangement can be provided which can include at least two further wave-guides which can be configured to receive the electro-magnetic radiations from the dispersive arrangement. Each of the further wave-guides can be structured and/or spatially arranged with respect to the dispersive arrangement to facilitate a receipt of a different one of the such electro-magnetic radiations as a function of wavelengths thereof.
摘要翻译：提供了根据本公开的装置和方法的示例性实施例。例如，可以提供用于向结构提供电磁辐射的装置。该示例性设备可以包括具有至少两个波导管的第一装置，该波导管可以被配置为通过至少两个彼此具有至少部分不同的波长的相应电磁辐射提供通过。示例性设备还可以包括色散第二布置，其被构造为接收电磁辐射并且将与相应电磁辐射相关联的至少两个散射辐射向前传递到结构的至少一个部分。（一个或多个）波导可以相对于弥散布置被结构化和/或空间布置，以促进分散辐射至少部分地在结构上重叠。另外，可以提供另一种布置，其可以包括至少两个另外的波导，其可以被配置为接收来自色散布置的电磁辐射。每个另外的波导可以相对于弥散布置被结构化和/或空间布置，以便于根据波长的函数接收不同的这种电磁辐射。

5. 发明申请

WO2009049296A2 SYSTEMS AND PROCESSES FOR OPTICAL IMAGING OF LUMINAL ANATOMIC STRUCTURES 审中-公开
标题翻译：系统和过程光学成像的解剖解剖结构
公开(公告)号：WO2009049296A2
公开(公告)日：2009-04-16
申请号：PCT/US2008/079736
申请日：2008-10-13
申请人： THE GENERAL HOSPITAL CORPORATION , SUTER, Melissa, J. , TEARNEY, Guillermo, J. , BOUMA, Brett, Eugene
发明人： SUTER, Melissa, J. , TEARNEY, Guillermo, J. , BOUMA, Brett, Eugene
IPC分类号： A61B1/00 , A61B5/00
CPC分类号： A61B5/6852 , A61B5/0066 , A61B5/0084 , A61B5/6853 , A61B5/6858 , A61B5/6886
摘要： Exemplary embodiments of an apparatus for obtaining data for at least one portion within at least one luminal or hollow sample can be provided. For example, the exemplary apparatus can include a first optical arrangement configured to transceive at least one electromagnetic radiation to and from the portion. A second arrangement may be provided that can at least partially enclose the first arrangement. At least one third arrangement may be provided which is configured to be actuated so as to expand, at least in part, beyond a periphery of the second arrangement. Such exemplary third arrangement can be structured to facilitate a fluid flow and/or a gas flow therethrough. Further, a fourth arrangement may be provided which can be structured to (i) actuate a particular number of the third arrangement and/or (ii) adjust a distance between at least two outer portions of the third arrangement. According to one exemplary embodiment, the third arrangement can be a plurality of the third arrangements.
摘要翻译：可以提供用于获得至少一个内腔或中空样品内的至少一部分的数据的设备的示例性实施方式。例如，该示例性装置可以包括第一光学装置，该第一光学装置被配置为向该部分收发至少一个电磁辐射并从该部分收发电磁辐射。可以提供第二布置，其可以至少部分地包围第一布置。可以提供至少一个第三布置，其被配置为被致动以便至少部分地扩展超出第二布置的外围。这样的示例性第三布置可被构造成便于流体流动和/或气体流过其中。此外，可以提供第四布置，其可以被构造成（i）致动特定数量的第三布置和/或（ii）调整第三布置的至少两个外部之间的距离。根据一个示例性实施例，第三装置可以是多个第三装置。

6. 发明申请

WO2008118781A2 METHODS, ARRANGEMENTS AND APPARATUS FOR UTILIZING A WAVELENGTH-SWEPT LASER USING ANGULAR SCANNING AND DISPERSION PROCEDURES 审中-公开
标题翻译：使用角度扫描和分散程序来使用波长切割激光的方法，装置和装置
公开(公告)号：WO2008118781A2
公开(公告)日：2008-10-02
申请号：PCT/US2008/057835
申请日：2008-03-21
申请人： THE GENERAL HOSPITAL CORPORATION , BOUMA, Brett, Eugene , MOTAGHIANNEZAM, Reza , TEARNEY, Guillermo, J.
发明人： BOUMA, Brett, Eugene , MOTAGHIANNEZAM, Reza , TEARNEY, Guillermo, J.
CPC分类号： G02B26/12 , G01J3/02 , G01J3/0208 , G01J3/021 , G01J3/0218 , G01J3/06 , G01J3/10 , G01J3/18 , G01J3/4338 , G01J2003/1286 , G01N21/39 , G02B26/002 , H01S5/141 , H01S5/143 , H01S5/146
摘要： Exemplary systems and methods for filtering an electromagnetic radiation can be provided. For example, at least one first arrangement can be provided which is capable of receiving at least one first electro-magnetic radiation and forwarding at least one second electro-magnetic radiation at different angles with respect to a direction of incidence of the first electro-magnetic radiation. At least one second wavelength dispersion arrangement can be provided which is configured to receive the second electro-magnetic radiation, forward at least one third electro-magnetic radiation to the first arrangement and further receive at least one fourth electro¬ magnetic radiation. The third electro-magnetic radiation can be based on the second electro-magnetic radiation, and the fourth electro-magnetic radiation can be based on the third electro-magnetic radiation. For example, the second arrangement can be configured to forward the second electro-magnetic radiation at different angles with respect to a direction of incidence of the at least one particular electro-magnetic radiation. Exemplary embodiments of methods can be provided to implement such exemplary techniques.
摘要翻译：可以提供用于过滤电磁辐射的示例性系统和方法。例如，可以提供至少一个第一布置，其能够接收至少一个第一电磁辐射并且相对于第一电磁场的入射方向以不同的角度转发至少一个第二电磁辐射辐射。可以提供至少一个第二波长色散布置，其被配置为接收第二电磁辐射，将至少一个第三电磁辐射向前转换到第一布置，并进一步接收至少一个第四电磁辐射。第三电磁辐射可以基于第二电磁辐射，第四电磁辐射可以基于第三电磁辐射。例如，第二布置可以被配置为相对于至少一个特定电磁辐射的入射方向以不同的角度转发第二电磁辐射。可以提供方法的示例性实施例来实现这种示例性技术。

7. 发明申请

WO2007041376A1 METHOD AND APPARATUS FOR OPTICAL IMAGING VIA SPECTRAL ENCODING 审中-公开
标题翻译：通过光谱编码进行光学成像的方法和装置
公开(公告)号：WO2007041376A1
公开(公告)日：2007-04-12
申请号：PCT/US2006/038213
申请日：2006-09-29
申请人： GENERAL HOSPITAL CORPORATION , TEARNEY, Guillermo, J. , YELIN, Dvir , BOUMA, Brett, Eugene
发明人： TEARNEY, Guillermo, J. , YELIN, Dvir , BOUMA, Brett, Eugene
IPC分类号： A61B5/00 , G01B11/24 , G01B9/02
CPC分类号： G01N33/4833 , A61B5/0062 , A61B5/0066 , A61B5/0068 , A61B5/0073 , A61B5/0075 , A61B5/0084 , A61B5/6852 , G01B9/02 , G01B9/02027 , G01B9/02049 , G01B9/02064 , G01B9/02087 , G01B9/02091 , G01B9/04 , G01N21/25 , G01N21/27 , G01N21/4795 , G01N21/6458 , G01N21/6486 , G01N23/046 , G01N2021/1765 , G01N2223/419 , G02B21/0028 , G02B23/2423 , G02B23/243 , G02B23/2461 , G02B23/2476
摘要： Method, apparatus and arrangement according an exemplary embodiment of the present invention can be provided for obtaining information associated with a sample such as a portion of an anatomical structure. The information can be generated using first data, which can be based on a signal obtained from a location on the sample, and second data, where the second data can be obtained by combining a second signal received from the sample with a third reference signal. An image of a portion of the sample can also be generated based on the information. For example, the first data can be associated with spectral encoding microscopy data, and the second data can be associated with optical coherence tomography data.
摘要翻译：可以提供根据本发明的示例性实施例的方法，装置和装置，用于获得与诸如解剖结构的一部分的样本相关联的信息。可以使用可以基于从样本上的位置获得的信号的第一数据和第二数据来生成信息，其中可以通过将从样本接收的第二信号与第三参考信号组合来获得第二数据。也可以基于该信息生成样本的一部分的图像。例如，第一数据可以与光谱编码显微镜数据相关联，并且第二数据可以与光学相干断层扫描数据相关联。

8. 发明申请

WO2007038787A1 METHOD AND APPARATUS FOR OPTICAL IMAGING VIA SPECTRAL ENCODING 审中-公开
标题翻译：通过光谱编码进行光学成像的方法和装置
公开(公告)号：WO2007038787A1
公开(公告)日：2007-04-05
申请号：PCT/US2006/038541
申请日：2006-09-29
申请人： GENERAL HOSPITAL CORPORATION , TEARNEY, Guillermo, J. , YELIN, Dvir , BOUMA, Brett, Eugene
发明人： TEARNEY, Guillermo, J. , YELIN, Dvir , BOUMA, Brett, Eugene
IPC分类号： A61B5/00 , A61B1/07 , G01B9/02
CPC分类号： G01N33/4833 , A61B5/0062 , A61B5/0066 , A61B5/0068 , A61B5/0073 , A61B5/0075 , A61B5/0084 , A61B5/6852 , G01B9/02 , G01B9/02027 , G01B9/02049 , G01B9/02064 , G01B9/02087 , G01B9/02091 , G01B9/04 , G01N21/25 , G01N21/27 , G01N21/4795 , G01N21/6458 , G01N21/6486 , G01N23/046 , G01N2021/1765 , G01N2223/419 , G02B21/0028 , G02B23/2423 , G02B23/243 , G02B23/2461 , G02B23/2476
摘要： Method, apparatus and arrangement according an exemplary embodiment of the present invention can be provided for generating an image of at least one portion of an anatomical structure. For example, the portion can have an area greater than about 1 mm2, and the image can have a resolution a transverse resolution that is below about lOμm. For example, light can be scanned over such portion so as to generate first information which is related to the portion, where the light may be provided through a diffraction arrangement to generate a spectrally dispersed line. Method, apparatus and arrangement according to a further exemplary embodiment of the present invention can be provided for positioning a radiation or optical beam within an anatomical structure based on signals generated by scanning a portion of the structure using the same or a different beam.
摘要翻译：可以提供根据本发明的示例性实施例的方法，装置和装置，用于生成解剖结构的至少一部分的图像。例如，该部分可以具有大于约1mm 2的面积，并且图像可以具有低于约10μm的横向分辨率的分辨率。例如，可以在这样的部分上扫描光，以便产生与该部分相关的第一信息，其中可以通过衍射装置提供光以产生光谱分散的线。可以提供根据本发明的另一示例性实施例的方法，装置和布置，其基于通过使用相同或不同的束扫描结构的一部分而产生的信号来将辐射或光束定位在解剖结构内。

9. 发明申请

WO2007019574A2 APPARATUS, METHODS AND STORAGE MEDIUM FOR PERFORMING POLARIZATION-BASED QUADRATURE DEMODULATION IN OPTICAL COHERENCE TOMOGRAPHY 审中-公开
标题翻译：用于在光学相干平台中进行基于偏振度的平移解调的装置，方法和存储介质
公开(公告)号：WO2007019574A2
公开(公告)日：2007-02-15
申请号：PCT/US2006/031275
申请日：2006-08-09
申请人： THE GENERAL HOSPITAL CORPORATION , VAKOC, Benjamin, J. , YUN, Seok-Hyun , TEARNEY, Guillermo, J. , BOUMA, Brett, Eugene
发明人： VAKOC, Benjamin, J. , YUN, Seok-Hyun , TEARNEY, Guillermo, J. , BOUMA, Brett, Eugene
IPC分类号： G01B9/02 , G01N21/47
CPC分类号： G01B9/02044 , A61B5/0059 , A61B5/0066 , G01B9/02004 , G01B9/02072 , G01B9/02081 , G01B9/02091 , G01B2290/45 , G01B2290/70 , G01J3/45 , G01J2009/0265 , G01N21/21 , G01N21/274 , G01N21/4795
摘要： Apparatus, method and storage medium which can provide at least one first electro-magnetic radiation to a sample and at least one second electro-magnetic radiation to a reference, such that the first and/or second electro-magnetic radiations have a spectrum which changes over time. In addition, a first polarization component of at least one third radiation associated with the first radiation can be combined with a second polarization component of at least one fourth radiation associated with the second radiation with one another. The first and second polarizations may be specifically controlled to be at least approximately orthogonal to one another.
摘要翻译：可以向样品提供至少一个第一电磁辐射和至少一个第二电磁辐射至参考的装置，方法和存储介质，使得第一和/或第二电磁辐射具有改变的光谱随着时间的推移。此外，与第一辐射相关联的至少一个第三辐射的第一偏振分量可以与与第二辐射相关联的至少一个第四辐射的第二偏振分量彼此组合。可以将第一和第二偏振特别地控制为至少大致彼此正交。

10. 发明申请

WO2006130802A3 APPARATUS, METHOD AND SYSTEM FOR PERFORMING PHASE-RESOLVED OPTICAL FREQUENCY DOMAIN IMAGING 审中-公开
公开(公告)号：WO2006130802A3
公开(公告)日：2006-12-07
申请号：PCT/US2006/021375
申请日：2006-06-01
申请人： THE GENERAL HOSPITAL CORPORATION , VAKOC, Benjamin, J. , YUN, Seok-Hyun , TEARNEY, Guillermo, J. , BOUMA, Brett, Eugene , DE BOER, Johannes, F.
发明人： VAKOC, Benjamin, J. , YUN, Seok-Hyun , TEARNEY, Guillermo, J. , BOUMA, Brett, Eugene , DE BOER, Johannes, F.
IPC分类号： G01N21/47 , G01N21/49 , G01N21/45 , G01B9/02
摘要： Apparatus, system and method are provided which utilize signals received from a reference and a sample. In particular, a radiation is provided which includes at least one first electro-magnetic radiation directed to the sample and at least one second electro-magnetic radiation directed to the reference. A frequency of the radiation varies over time. An interference can be detected between at least one third radiation associated with the first radiation and at least one fourth radiation associated with the second radiation. It is possible to obtain a particular signal associated with at least one phase of at least one frequency component of the interference, and compare the particular signal to at least one particular information. Further, it is possible to receive at least one portion of the radiation and provide a further radiation, such that the particular signal can be calibrated based on the further signal.

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