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    • 5. 发明申请
    • CONTROL AND REPELLENCY OF MOSQUITOES
    • MOSQUITOES的控制和回报
    • WO2013165477A1
    • 2013-11-07
    • PCT/US2013/000121
    • 2013-04-30
    • BEDOUKIAN RESEARCH, INC.BEDOUKIAN, Robert, H.
    • BEDOUKIAN, Robert, H.
    • A01N37/10A01N35/00
    • A01N49/00A01N31/06A01N35/06A01N37/02A01N37/18A01N37/36A01N37/42A01N43/08A01N43/16A01N2300/00A01N37/10
    • Control or repellency of mosquitoes is accomplished by bringing the insects into contact with at least one of the compounds of the structure (I): Formula (I) wherein R is selected from -OH, =O, -OC(O)R 4 , -OR 6 , -(OR) 2 , wherein each R 6 is independently selected from an alkyl group containing from 1 to 4 carbon atoms and R 4 is a branched or straight chain, saturated or unsaturated hydrocarbyl group with zero to two double bonds and from 1 to 15 carbon atoms; X is O or CH 2 , with the proviso that when X is O R can only be =O; each Z is independently selected from (CH) and (CH 2 ); y is a numeral selected from 1 and 2; R 1 is selected from H or a branched or straight chain, saturated or unsaturated hydrocarbyl group with zero to two double bonds and from 1 to 15 carbon atoms; R 2 is selected from H and a branched or straight chain, saturated or unsaturated hydrocarbyl group with zero to three double bonds and from 1 to 15 carbon atoms; R 3 is selected from the group consisting of H and a branched or straight chain, saturated or unsaturated hydrocarbyl group with zero to three double bonds and from 1 to 15 carbon atoms, -(CH 2 ) n OH, -C(O)OR 5 , -CH 2 C(O)OR 7 , -CH 2 C(O)R 8 , -C(O)NR 9 R 10 , -CH 2 C(O)NR 11 R 12 where each of R 5 , R 7 , R 8 , R 9 ,R 10 , R 11 and R 12 is independently selected from H and a branched or straight chain, saturated or unsaturated hydrocarbyl group with zero to three double bonds and from 1 to 15 carbon atoms and n is an integer of from 1 to 12; the bond between the 2 and 3 positions in the ring structure may be a single or a double bond; and wherein the compounds of structure (I) contain from 11 to 20 total carbon atoms in the compounds, with the proviso that when R is =0, X is CH 2 , Z is CH 2 , y is 1 R 2 is H, and R 3 is CH 2 C(0)OR 7 then the total number of carbon atoms in the compounds of structure (I) is from 15 to 20 carbon atoms, and when X is O and R is =O the total number of carbon atoms in the compounds of structure (I) is from 11 to 17 carbon atoms. The invention also includes optical isomers, diastereomers and enantiomers of the named structures. Thus, at all stereocenters where stereochemistry is not explicitly defined, all possible epimers are envisioned.
    • 通过使昆虫与结构(I)的至少一种化合物接触来实现蚊子的控制或排斥:式(I)其中R选自-OH,= O,-OC(O)R 4, - OR 6, - (OR)2,其中每个R 6独立地选自含有1至4个碳原子的烷基,R 4是具有0至2个双键和1至15个碳原子的支链或直链,饱和或不饱和烃基 碳原子 X是O或CH2,条件是当X是O时,R只能是= O; 每个Z独立地选自(CH)和(CH 2); y是选自1和2的数字; R 1选自H或具有0至2个双键和1至15个碳原子的支链或直链饱和或不饱和烃基; R2选自H和具有0至3个双键和1至15个碳原子的支链或直链饱和或不饱和烃基; R3选自H和具有0至3个双键和1至15个碳原子的支链或直链饱和或不饱和烃基, - (CH 2)n OH,-C(O)OR 5,-CH 2 C (O)OR 7,-CH 2 C(O)R 8,-C(O)NR 9 R 10,-CH 2 C(O)NR 11 R 12,其中R 5,R 7,R 8,R 9,R 10,R 11和R 12各自独立地选自H和支链或 具有0至3个双键和1至15个碳原子的直链,饱和或不饱和烃基,n为1至12的整数; 环结构中2和3位之间的键可以是单键或双键; 并且其中结构(I)的化合物在化合物中含有11至20个总碳原子,条件是当R为0时,X为CH 2,Z为CH 2,y为1 R 2为H,且R 3为CH 2 C (0)OR7,结构(I)化合物中碳原子总数为15〜20个碳原子,当X为O且R为= O时,结构(I)化合物中的碳原子总数 )为11至17个碳原子。 本发明还包括命名结构的光学异构体,非对映体和对映异构体。 因此,立体化学没有明确定义的所有立体中心者,都设想到所有可能的差异。
    • 8. 发明申请
    • FEEDING DETERRENCE OF PESTS SUCH AS HEMIPTERA, LEPIDOPTERA AND COLEOPTERA
    • US20200022367A1
    • 2020-01-23
    • US16531446
    • 2019-08-05
    • BEDOUKIAN RESEARCH, INC.
    • Robert H. BEDOUKIAN
    • A01N43/16A01N31/06A01N37/02A01N37/36A01N37/42A01N43/08A01N35/06A01N49/00A01N37/06A01N37/18
    • Compounds are used as agents that deter feeding by insect pests, such as Hemiptera, Lepidoptera and Coleoptera. Feeding deterrence is obtained by contact of the insect pests with at least one of the compounds of the structure (I) wherein R is —OH, ═O, —OC(O)R4, —OR6, or —(OR6)2, each R6 is independently an alkyl group containing from 1 to 4 carbon atoms and R4 is a branched or straight chain, saturated or unsaturated, hydrocarbyl group with zero to two double bonds and from 1 to 15 carbon atoms; X is O or CH2 with the proviso that when X is O, R can only be ═O; each Z is independently (CH) or (CH2); y is a numeral selected from 1 and 2; R1 is H or a branched or straight chain, saturated or unsaturated hydrocarbyl group with zero to two double bonds and from 1 to 15 carbon atoms; R2 is H or a branched or straight chain, saturated or unsaturated hydrocarbyl group with zero to three double bonds and from 1 to 15 carbon atoms; R3 is selected from H, a branched or straight chain, saturated or unsaturated hydrocarbyl group with zero to three double bonds and from 1 to 15 carbon atoms, —(CH2)nOH, —C(O)OR5, —CH2C(O)OR7, —CH2C(O)R8, —C(O)NR9R10, and —CH2C(O)NR11R12 where each of R5, R7, R8, R9, R10, R11 and R12 is independently selected from H and a branched or straight chain, saturated or unsaturated hydrocarbyl group with zero to three double bonds and from 1 to 15 carbon atoms and n is an integer of from 1 to 12; the bond between the 2 and 3 positions in the ring structure may be a single or a double bond; and wherein the compounds of structure (I) contain from 9 to 20 total carbon atoms in the compounds.
    • 9. 发明申请
    • CONTROL AND REPELLENCY OF BED BUGS
    • US20190389793A1
    • 2019-12-26
    • US16559752
    • 2019-09-04
    • BEDOUKIAN RESEARCH, INC.
    • Robert H. Bedoukian
    • C07C69/675A01N31/06A01N37/18A01N43/08A01N43/16A01N37/22A01N37/36A01N37/42C07C35/06C07C35/18C07C59/205C07C69/708C07C235/74C07D307/33C07D309/30
    • Control or repellency of bed bugs is accomplished by bringing the bed bugs into contact with at least one of the compounds of the structure (I) Wherein R is selected from —OH, —OC(O)R4, —OR6, —(OR6)2, wherein each R6 is independently selected from an alkyl group containing from 1 to 4 carbon atoms and R4 is a branched or straight chain saturated or unsaturated hydrocarbyl group with zero to two double bonds and from 1 to 15 carbon atoms; X is O or CH2, with the proviso that when X is O, R can only be ═O; each Z is independently selected from (CH) and (CH2) y is a numeral selected from 1 and 2; R1 is selected from H or a branched or straight chain saturated or unsaturated hydrocarbyl group with zero to two double bonds and from 1 to 15 carbon atoms. R2 is selected from H and a branched or straight chain saturated or unsaturated hydrocarbyl group with zero to three double bonds and from 1 to 15 carbon atoms. R3 is selected from H, a branched or straight chain, saturated or unsaturated hydrocarbyl group with zero to three double bonds and from 1 to 15 carbon atoms, —(CH2)nOH, —C(O)OR5, —CH2C(O)OR7, —CH2C(O)R8, —C(O)NR9R10, —CH2C(O)NR11R12 where each of R5, R7, R8, R9, R10, R11 and R12 is independently selected from H and a branched or straight chain, saturated or unsaturated hydrocarbyl group with zero to three double bonds and from 1 to 15 carbon atoms, and n is an integer of from 1 to 12; and the bond between the 2 and 3 positions in the ring structure may be a single or a double bond, and wherein the compounds of structure (1) contain from 11 to 20 total carbon atoms, except where R is ═O, X═CH2 and y is 1 the compounds of structure (I) contain from 13 to 20 total carbon atoms in the compounds. wherein the compounds of structure (1) contain from 11 to 20 total carbon atoms, except where R is ═O, X═CH2 and y is 1 the compounds of structure (I) contain from 13 to 20 total carbon atoms in the compounds. wherein the compounds of structure (1) contain from 11 to 20 total carbon atoms, except where R is ═O, X═CH2 and y is 1 the compounds of structure (I) contain from 13 to 20 total carbon atoms in the compounds.