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    • 2. 发明公开
    • An imaging mass spectrometry principle and its application in a device
    • Bildmassenspektrometrie-Verfahren和seine Anwendung在einer Vorrichtung
    • EP2110845A1
    • 2009-10-21
    • EP08154620.2
    • 2008-04-16
    • Bamberger, CasimirBamberger, Andreas
    • Bamberger, CasimirBamberger, Andreas
    • H01J49/00
    • H01J49/0004H01J49/025H01J49/40
    • A method of imaging mass spectroscopy and a corresponding apparatus are provided, wherein the m/z-ratio of ions as well as the location of said ions on a sample surface are detected simultaneously in a time of flight mass spectrometer. The detector is a semiconductor array detector comprising pixels, that each can be arranged to measure a signal intensity of a signal induced by the ions or their time of arrival. A four-dimensional image consisting of the two lateral dimensions on the sample surface, the m/z-ratio representing the ion type and the abundance of an ion type on the surface can be reconstructed from repeated measurements for which a correspondingly adapted computer program product can be involved.
    • 提供了一种成像质谱法和相应装置的方法,其中在飞行时间质谱仪中同时检测离子的m / z比以及样品表面上的所述离子的位置。 检测器是包括像素的半导体阵列检测器,每个可以被布置成测量由离子引起的信号的信号强度或其到达时间。 由样品表面上的两个横向尺寸组成的四维图像,表示离子类型的离子类型的m / z比和表面上离子类型的丰度可以从重复测量重建,相应地适应的计算机程序产品 可以参与