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1. 发明申请

US20160068593A1 MONOCLONAL ANTIBODY AGAINST NECROSIS MARKER PRDX4 AND USE THEREOF 审中-公开
标题翻译：单克隆抗体抗体标记PRDX4及其用途
公开(公告)号：US20160068593A1
公开(公告)日：2016-03-10
申请号：US14849742
申请日：2015-09-10
申请人： Sumio SUGANO , Yukari KANZAKI , Tsuneo SAGA , Atsushi TSUJI
发明人： Sumio SUGANO , Yukari KANZAKI , Tsuneo SAGA , Atsushi TSUJI
IPC分类号： C07K16/18 , A61K51/10 , G01N33/574
CPC分类号： G01N33/574 , A61K51/1045 , A61K51/1093 , C07K16/18 , C07K16/30 , C07K2317/14 , C07K2317/76 , C07K2317/92 , G01N33/57496 , G01N2333/47 , G01N2333/908 , G01N2800/00
摘要： [PROBLEM] To provide a monoclonal antibody against a biomarker which shows high specificity and can be effectively used in detection and diagnosis of various lesions relevant to various kinds of carcinomas and foci of necrosis, and so forth.[MEANS] A monoclonal antibody against a necrosis marker consisting the following amino acid sequence: (1) the amino acid sequence of SEQ ID NO: 1, or (2) an amino acid sequence having substitution, deletion and/or insertion of one or several amino acid residues in the amino acid sequence of (1) or sharing a homology of 90% or more with the amino acid sequence of (1), and showing the same function, activity or property as that of the amino acid sequence of (1) as a protein.
摘要翻译：提供针对生物标志物的单克隆抗体，其显示高特异性并且可以有效地用于检测和诊断与各种癌症和坏死灶相关的各种损伤等。一种针对包含以下氨基酸序列的坏死标记的单克隆抗体：（1）SEQ ID NO：1的氨基酸序列，或（2）具有取代，缺失和/或插入的氨基酸序列之一或（1）的氨基酸序列中的几个氨基酸残基或与（1）的氨基酸序列具有90％以上的同源性，并且与（1）的氨基酸序列具有相同的功能，活性或性质 1）作为蛋白质。

2. 发明申请

US20130040311A1 MONOCLONAL ANTIBODY AGAINST NECROSIS MARKER ERP29 AND USE THEREOF 有权
标题翻译：单克隆抗体对NECROSIS MARKER ERP29及其用途
公开(公告)号：US20130040311A1
公开(公告)日：2013-02-14
申请号：US13583312
申请日：2011-03-08
申请人： Sumio Sugano , Yukari Kanzaki , Tsuneo Saga , Atsushi Tsuji
发明人： Sumio Sugano , Yukari Kanzaki , Tsuneo Saga , Atsushi Tsuji
IPC分类号： G01N33/566 , C07K16/18 , G01N33/573
CPC分类号： G01N33/574 , A61K51/1045 , A61K51/1093 , C07K16/18 , C07K16/30 , C07K2317/14 , C07K2317/76 , C07K2317/92 , G01N33/57496 , G01N2333/47 , G01N2333/908 , G01N2800/00
摘要： [PROBLEM] To provide a monoclonal antibody against a biomarker which shows high specificity and can be effectively used in detection and diagnosis of various lesions relevant to various kinds of carcinomas and foci of necrosis, and so forth.[MEANS] A monoclonal antibody against a necrosis marker consisting the following amino acid sequence: (1) the amino acid sequence of any of SEQ ID NOs: 1 to 3, or (2) an amino acid sequence having substitution, deletion and/or insertion of one or several amino acid residues in the amino acid sequence of (1) or sharing a homology of 90% or more with the amino acid sequence of (1), and showing the same function, activity or property as that of the amino acid sequence of (1) as a protein.
摘要翻译：提供针对生物标志物的单克隆抗体，其显示高特异性并且可以有效地用于检测和诊断与各种癌症和坏死灶相关的各种损伤等。构成下列氨基酸序列的抗坏血酸标记单克隆抗体：（1）SEQ ID NO：1〜3中任一项所述的氨基酸序列，或（2）具有取代，缺失和/或缺失的氨基酸序列在（1）的氨基酸序列中插入一个或几个氨基酸残基或与（1）的氨基酸序列共享90％以上的同源性，并显示与氨基酸的氨基酸序列相同的功能，活性或性质（1）的酸序列作为蛋白质。

3. 发明授权

US08292203B2 Method for granulating ethylene/tetrafluoroethylene copolymer 有权
标题翻译：乙烯/四氟乙烯共聚物造粒方法
公开(公告)号：US08292203B2
公开(公告)日：2012-10-23
申请号：US13163800
申请日：2011-06-20
申请人： Shigeru Aida , Atsushi Tsuji , Akio Ogawa , Toshiyuki Chisaka , Jumpei Nomura
发明人： Shigeru Aida , Atsushi Tsuji , Akio Ogawa , Toshiyuki Chisaka , Jumpei Nomura
IPC分类号： B02C19/00
CPC分类号： C08F210/02 , C08F6/003 , C08F214/265 , C08L27/18 , C08L23/0892 , C08F214/26 , C08F2500/20 , C08F2500/24
摘要： To provide a method for producing ETFE granules having a low content of an ethylene/tetrafluoroethylene copolymer oligomer and being excellent in handling efficiency. A method for granulating an ethylene/tetrafluoroethylene copolymer, which is characterized by stirring and granulating a slurry of an ethylene/tetrafluoroethylene copolymer together with water in the presence of both ethylene and tetrafluoroethylene at a granulation temperature of from 10 to 130° C. for a granulation time of from 30 to 240 minutes.
摘要翻译：提供一种生产乙烯/四氟乙烯共聚物低聚物含量低的处理效率优异的ETFE颗粒的方法。一种乙烯/四氟乙烯共聚物造粒方法，其特征在于在乙烯和四氟乙烯存在下，在造粒温度为10-130℃下，将乙烯/四氟乙烯共聚物的浆料与水一起搅拌并造粒，造粒时间为30〜240分钟。

4. 发明申请

US20120263849A1 BITTERNESS SUPPRESSION METHOD 审中-公开
标题翻译：双向抑制方法
公开(公告)号：US20120263849A1
公开(公告)日：2012-10-18
申请号：US13253481
申请日：2011-10-05
申请人： Atsushi TSUJI
发明人： Atsushi TSUJI
IPC分类号： A23L1/221 , A23F3/16 , A23L2/56
CPC分类号： A23F3/163 , A23L2/52 , A23L27/86
摘要： Provided is a bitterness suppression method capable of effectively suppressing an unpleasant bitterness. Also, provided is a bitterness suppression method including incorporating methyl salicylate in a composition having a bitterness.
摘要翻译：提供能够有效地抑制不愉快的苦味的苦味抑制方法。此外，提供了一种苦味抑制方法，包括在具有苦味的组合物中并入水杨酸甲酯。

5. 发明申请

US20110240773A1 METHOD FOR GRANULATING ETHYLENE/TETRAFLUOROETHYLENE COPOLYMER 有权
标题翻译：乙烯/四氟乙烯共聚物造粒方法
公开(公告)号：US20110240773A1
公开(公告)日：2011-10-06
申请号：US13163800
申请日：2011-06-20
申请人： Shigeru Aida , Atsushi Tsuji , Akio Ogawa , Toshiyuki Chisaka , Jumpei Nomura
发明人： Shigeru Aida , Atsushi Tsuji , Akio Ogawa , Toshiyuki Chisaka , Jumpei Nomura
IPC分类号： B02C23/00
CPC分类号： C08F210/02 , C08F6/003 , C08F214/265 , C08L27/18 , C08L23/0892 , C08F214/26 , C08F2500/20 , C08F2500/24
摘要： To provide a method for producing ETFE granules having a low content of an ethylene/tetrafluoroethylene copolymer oligomer and being excellent in handling efficiency. A method for granulating an ethylene/tetrafluoroethylene copolymer, which is characterized by stirring and granulating a slurry of an ethylene/tetrafluoroethylene copolymer together with water in the presence of both ethylene and tetrafluoroethylene at a granulation temperature of from 10 to 130° C. for a granulation time of from 30 to 240 minutes.
摘要翻译：提供一种生产乙烯/四氟乙烯共聚物低聚物含量低的处理效率优异的ETFE颗粒的方法。一种乙烯/四氟乙烯共聚物造粒方法，其特征在于在乙烯和四氟乙烯存在下，在造粒温度为10-130℃下，将乙烯/四氟乙烯共聚物的浆料与水一起搅拌并造粒，造粒时间为30〜240分钟。

6. 发明申请

US20090074897A1 AGENT FOR ELEVATING ADIPONECTIN CONCENTRATION 审中-公开
标题翻译：用于排放ADIPONECTIN浓度的试剂
公开(公告)号：US20090074897A1
公开(公告)日：2009-03-19
申请号：US11994336
申请日：2006-07-11
申请人： Yoriko Deguchi , Kumiko Makino , Kotaro Takamizawa , Tsuguyoshi Asano , Atsushi Tsuji
发明人： Yoriko Deguchi , Kumiko Makino , Kotaro Takamizawa , Tsuguyoshi Asano , Atsushi Tsuji
IPC分类号： A61K36/61 , A61K127/00 , A61P5/00
CPC分类号： A61K36/61 , A23L33/105 , A23L33/185 , A23V2002/00 , A23V2200/332 , A23V2250/21
摘要： To provide a highly safe medicament or food or beverage which exhibits the effect of elevating blood adiponectin level, and which allows intake thereof over a long period of time. The invention provides an adiponectin level elevating agent including guava leaf extract as an active ingredient.
摘要翻译：提供表现出提高血液中脂联素水平的作用的高度安全的药物或食品或饮料，并且其允许长时间摄入。本发明提供包含番石榴叶提取物作为活性成分的脂联素水平升高剂。

7. 发明授权

US06187773B1 Hexahydrotriazine compounds and insecticides 失效
标题翻译：六氢三嗪化合物和杀虫剂
公开(公告)号：US06187773B1
公开(公告)日：2001-02-13
申请号：US07606848
申请日：1990-10-31
申请人： Frank Wu , Akinori Kariya , Noriyoshi Katsuyama , Atsushi Tsuji , Kiyoshi Takasuka , Shigenori Segami , Katsumi Nanjo , Junko Sato
发明人： Frank Wu , Akinori Kariya , Noriyoshi Katsuyama , Atsushi Tsuji , Kiyoshi Takasuka , Shigenori Segami , Katsumi Nanjo , Junko Sato
IPC分类号： A01N4366
CPC分类号： C07D401/06 , A01N51/00 , C07D401/14 , C07D417/06
摘要： A hexahydrotrazine compound which is 1-(2-chloro-5-pyridylmethyl)-3,5-dimethyl-2-nitroiminohexahydro-1,3,5-triazine or 1-(2-chloro-5-thiazolylmethyl)-3,5-dimethyl-2-nitroiminiohexahydro-1,3,5-triazine and insecticides containing the same.
摘要翻译： 1-（2-氯-5-吡啶基甲基）-3,5-二甲基-2-硝基亚氨基六氢-1,3,5-三嗪或1-（2-氯-5-噻唑基甲基）-3,5的六氢四嗪化合物 - 二甲基-2-硝基亚氨基六氢-1,3,5-三嗪和含有它们的杀虫剂。

8. 发明申请

US20120328528A1 MONOCLONAL ANTIBODY AGAINST NECROSIS MARKER PRDX4 AND USE THEREOF 有权
标题翻译：单克隆抗体抗体标记PRDX4及其用途
公开(公告)号：US20120328528A1
公开(公告)日：2012-12-27
申请号：US13583524
申请日：2011-03-08
申请人： Sumio Sugano , Yukari Kanzaki , Tsuneo Saga , Atsushi Tsuji
发明人： Sumio Sugano , Yukari Kanzaki , Tsuneo Saga , Atsushi Tsuji
IPC分类号： C07K16/18 , A61K49/04 , A61K49/00 , G01N33/573
CPC分类号： G01N33/574 , A61K51/1045 , A61K51/1093 , C07K16/18 , C07K16/30 , C07K2317/14 , C07K2317/76 , C07K2317/92 , G01N33/57496 , G01N2333/47 , G01N2333/908 , G01N2800/00
摘要： [PROBLEM] To provide a monoclonal antibody against a biomarker which shows high specificity and can be effectively used in detection and diagnosis of various lesions relevant to various kinds of carcinomas and foci of necrosis, and so forth.[MEANS] A monoclonal antibody against a necrosis marker consisting the following amino acid sequence: (1) the amino acid sequence of SEQ ID NO: 1, or (2) an amino acid sequence having substitution, deletion and/or insertion of one or several amino acid residues in the amino acid sequence of (1) or sharing a homology of 90% or more with the amino acid sequence of (1), and showing the same function, activity or property as that of the amino acid sequence of (1) as a protein.
摘要翻译：提供针对生物标志物的单克隆抗体，其显示高特异性并且可以有效地用于检测和诊断与各种癌症和坏死灶相关的各种损伤等。一种针对包含以下氨基酸序列的坏死标记的单克隆抗体：（1）SEQ ID NO：1的氨基酸序列，或（2）具有取代，缺失和/或插入的氨基酸序列之一或（1）的氨基酸序列中的几个氨基酸残基或与（1）的氨基酸序列具有90％以上的同源性，并且与（1）的氨基酸序列具有相同的功能，活性或性质 1）作为蛋白质。

9. 发明申请

US20080052504A1 Method and system for rebooting a processor in a multi-processor system 失效
标题翻译：在多处理器系统中重新启动处理器的方法和系统
公开(公告)号：US20080052504A1
公开(公告)日：2008-02-28
申请号：US11509493
申请日：2006-08-24
申请人： Atsushi Tsuji , Chiaki Takano , Atsuo Mangyo , Masaaki Nozaki , Shunsaku Tokito , Hiroaki Terakawa
发明人： Atsushi Tsuji , Chiaki Takano , Atsuo Mangyo , Masaaki Nozaki , Shunsaku Tokito , Hiroaki Terakawa
IPC分类号： G06F15/177
CPC分类号： G06F9/4418
摘要： Processors arranged in a multi-processor configuration for substantially parallel operations receive their initialization data in order to start operations, such as graphics computations, real-time multimedia streaming, etc. Due to a change in the processing load, one or more processors might be deactivated. Subsequently, the load increases to such a level that requires all or some of the deactivated processors to be active again. In this case, the boot-up process of the entire system is not carried out as it would be time-consuming and wasteful; instead, responsive to a control signal only those processors that were previously in inactive mode are re-initialized by selecting a configuration data supplied by another processor, controller or any other intelligent programmable device. Alternatively, the configuration data may be accessed and retrieved from a local storage medium individually located in each processor, thereby re-booting only those inactive processors and without re-initializing the entire system.
摘要翻译：以多处理器配置布置的用于基本并行操作的处理器接收它们的初始化数据，以便开始诸如图形计算，实时多媒体流等操作。由于处理负载的变化，一个或多个处理器可能是停用随后，负载增加到要求全部或一些停用处理器再次活动的水平。在这种情况下，整个系统的启动过程不会执行，因为这将是耗时且浪费的; 相反，响应于控制信号，仅通过选择由另一个处理器，控制器或任何其他智能可编程设备提供的配置数据来重新初始化先前处于非活动模式的处理器。或者，可以从单独位于每个处理器中的本地存储介质访问和检索配置数据，从而仅重新引导那些不活动的处理器，并且不重新初始化整个系统。

10. 发明授权

US5997034A Air bag made of resin 失效
标题翻译：气囊由树脂制成
公开(公告)号：US5997034A
公开(公告)日：1999-12-07
申请号：US526644
申请日：1995-09-11
申请人： Kinji Hirai , Hiroshi Tomita , Atsushi Tsuji
发明人： Kinji Hirai , Hiroshi Tomita , Atsushi Tsuji
IPC分类号： B29D22/00 , B29K75/00 , B60R21/16 , B60R21/235 , C08L75/00 , C08L75/04 , B60R21/20
CPC分类号： B60R21/235
摘要： An air bag is made of thermoplastic urethane resin. The resin has a hardness (Shore scale A) of 88 to 92 measured by JIS K-7311; a tensile strength of 400 kg/cm.sup.2 or more measured by JIS K-7311; a breaking elongation of 400% or more measured by JIS K-7311; a 100% modulus of 70 kg/cm.sup.2 or more measured by JIS K-7311; a 300% modulus of 150 kg/cm.sup.2 or more measured by JIS k-7311; a tearing strength of 75 kg/cm or more measured by JIS K-7311; a pour point of 180.degree. C. to 188.degree. C. measured by Flow Tester; and a melting viscosity of 2.5.times.10.sup.5 Ps/190.degree. C. to 45.times.10.sup.5 Ps/190.degree. C. measured by Flow Tester.
摘要翻译：气囊由热塑性聚氨酯树脂制成。该树脂具有通过JIS K-7311测定的88〜92的硬度（肖氏标度A）。通过JIS K-7311测定的拉伸强度为400kg / cm 2以上; 通过JIS K-7311测定的断裂伸长率为400％以上; 通过JIS K-7311测定的70kg / cm 2以上的100％模量; 通过JIS k-7311测定的300kg / cm 2以上的300％模量; 通过JIS K-7311测定的撕裂强度为75kg / cm以上; 通过流动测试仪测量的倾点为180℃至188℃; 并且通过流动测试仪测量的熔融粘度为2.5×10 5 Ps / 190℃至45×105ps / 190℃。

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