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    • 1. 发明申请
    • Method and composition for analyzing a carbohydrate polymer
    • 用于分析碳水化合物聚合物的方法和组合物
    • US20070092915A1
    • 2007-04-26
    • US11402646
    • 2006-04-11
    • Ofer MarkmanAssaf (Assaph) OronChana Rothmann-Schertz
    • Ofer MarkmanAssaf (Assaph) OronChana Rothmann-Schertz
    • G01N33/53C12Q1/42G06T7/00
    • G01N33/5308G01N2400/00
    • Disclosed is a method for characterizing carbohydrate polymer by identifying at least two binding agents that bind to the carbohydrate polymer. Binding is preferably determined by contacting the carbohydrate polymer with substrate that contains a plurality of first saccharide-binding agents affixed at predetermined locations on the substrate. The carbohydrate polymer is allowed to contact the substrate under conditions that allow for formation of a first complex between the first saccharide-binding agent and the carbohydrate polymer. A second saccharide-binding agent, which preferably includes a label, is also contacted with the carbohydrate polymer under conditions that allow for formation of a second complex between the second binding agent and the first complex. Identification of the first and second binding agent allows for characterization of the polysaccharide.
    • 公开了通过鉴定结合碳水化合物聚合物的至少两种结合剂来表征碳水化合物聚合物的方法。 优选通过使碳水化合物聚合物与含有固定在基材上预定位置的多个第一糖结合剂的底物接触来确定结合。 允许碳水化合物聚合物在允许在第一糖结合剂和碳水化合物聚合物之间形成第一配合物的条件下接触底物。 优选包括标签的第二糖结合剂在允许在第二结合剂和第一配合物之间形成第二配合物的条件下也与碳水化合物聚合物接触。 鉴定第一和第二结合剂允许表征多糖。