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1. 发明授权

US08394428B1 Formulations and methods for preventing eyebrow hair loss 有权
标题翻译：防止眉毛脱发的制剂和方法
公开(公告)号：US08394428B1
公开(公告)日：2013-03-12
申请号：US13229253
申请日：2011-09-09
申请人： Renata Marie Vestevich , Arun Nandagiri
发明人： Renata Marie Vestevich , Arun Nandagiri
IPC分类号： A61K36/00
CPC分类号： A61K8/34 , A61K8/86 , A61K8/97 , A61K36/71 , A61Q7/00
摘要： Compositions comprising from about 0.5 to about 40 percent by weight of black cohosh extract, from about 0.5 to about 20 percent by weight of nonionic surfactant, and from about to 40 about 99 percent by weight of hydroxylated solvent are effective in reducing and preventing eyebrow hair loss in patients undergoing chemotherapy.
摘要翻译：包含约0.5至约40重量％的黑咖啡提取物，约0.5至约20重量％的非离子表面活性剂和约40至99重量％的羟基化溶剂的组合物有效地减少和防止眉毛化疗患者的损失。

2. 发明授权

US5651961A Hair manageability and styling composition 失效
标题翻译：头发可管理性和造型组成
公开(公告)号：US5651961A
公开(公告)日：1997-07-29
申请号：US535759
申请日：1995-09-28
申请人： Paul Neill , Loralei Brandt , Priscilla Walling , Arun Nandagiri , Norman Meltzer
发明人： Paul Neill , Loralei Brandt , Priscilla Walling , Arun Nandagiri , Norman Meltzer
IPC分类号： A61K20060101 , A61K8/44 , A61K8/46 , A61Q5/04 , A61K7/09 , A61K7/06
CPC分类号： A61Q5/04 , A61K8/447 , A61K8/46
摘要： A mild permanent wave reducing agent-containing composition and method of permanently waving or straightening human hair that provides a strong, long lasting curl, or long lasting straight hair formation, while minimizing hair damage. The composition includes two ionic compounds, one cationic and the other anionic, that complex in solution to provide synergy in waving efficiency, thereby providing a strongly reconfigured hair configuration (curled or straightened). At least one of the ionic compounds functions as a reducing agent for hair, capable of breaking the disulfide bonds in the hair so that the bonds later can be reformed via oxidation, when the hair is in the desired configuration. Examples of cationic compounds include thiocholine, choline, cysteineamide, cysteamine, and combinations thereof. Examples of anionic compounds include cysteine, N-acetylcysteine, thioglycolic acid or its salts, and combinations thereof. The preferred ionic compounds are thiocholine and N-acetylcysteine. The composition is effective over a wide pH range of about 4 to about 12, especially about 5.0 to about 9.4, preferably in the range of about 5.5 to about 8.5, and more preferably at a neutral pH of about 7.0.+-.1.0.
摘要翻译：一种温和的永久性挥发性还原剂组合物和永久挥发或矫直人发的方法，其提供强烈的，持久的卷曲或持久的直发形成，同时最小化头发损伤。该组合物包括两种离子化合物，一种阳离子和另一种阴离子，其在溶液中复合，以提供挥发效率的协同作用，从而提供强烈重新配置的头发构型（卷曲或拉直）。至少一种离子化合物起着毛发的还原剂的作用，能够破坏毛发中的二硫键，使得当毛发处于所需构型时，随后的粘合可通过氧化重整。阳离子化合物的实例包括硫代胆碱，胆碱，半胱氨酸，半胱胺及其组合。阴离子化合物的实例包括半胱氨酸，N-乙酰半胱氨酸，巯基乙酸或其盐，以及它们的组合。优选的离子化合物是硫代胆碱和N-乙酰半胱氨酸。该组合物在约4至约12，特别是约5.0至约9.4，优选约5.5至约8.5，更优选约7.0 +/- 1.0的中性pH的宽pH范围内有效。

3. 发明授权

US5601813A Cysteamine permanent wave composition and method 失效
标题翻译：半胱胺永久性波浪组成及方法
公开(公告)号：US5601813A
公开(公告)日：1997-02-11
申请号：US510428
申请日：1995-08-02
申请人： Arun Nandagiri , Richard A. Abbott , Renee E. Nardone , Edward T. Borish
发明人： Arun Nandagiri , Richard A. Abbott , Renee E. Nardone , Edward T. Borish
IPC分类号： A45D2/12 , A45D7/04 , A61K8/46 , A61Q5/04 , A61K7/06 , A61K7/11
CPC分类号： A61K8/46 , A61Q5/04
摘要： A single formula, mild permanent wave reducing composition and method of permanently waving or reshaping human hair that provides a strong, long lasting curl and leaves the hair soft while minimizing further damage to already damaged hair. The composition contains a cysteamine reducing agent compound selected from the group consisting of cysteamine, a cysteamine salt, and mixtures thereof. The cysteamine compound should be present in an amount of at least about 7.8% by weight and preferably in the range of about 7.8% to about 12.5% by weight; and sufficient additional alkali, if necessary, to bring the pH of the composition to at least about 7.8 preferably about 7.8 to about 8.8. Optionally, a hair softening and/or moisturizing agent, such as glycerine is included in the composition in an amount of about 0.1% to about 15% by weight of the composition. The composition can be lotion or water wrapped and can be used with or without heat. Unexpectedly, the composition is applied to any type of hair, regardless of structural damage to the hair, resulting in the same degree of curl tightness and softness and can be applied much more frequently than prior art permanent wave compositions without significant damage to the hair.
摘要翻译：一种单一的配方，温和的永久性波浪减少组合物和永久挥发或重塑人类头发的方法，提供强烈的，持久的卷曲，并使头发柔软，同时最大限度地减少已损坏的头发的进一步损伤。该组合物含有选自半胱胺，半胱胺盐及其混合物的半胱胺还原剂化合物。半胱胺化合物的存在量应为至少约7.8重量％，优选约7.8重量％至约12.5重量％; 和足够的额外的碱，如果需要，使组合物的pH至少约7.8，优选约7.8至约8.8。任选地，组合物中包含头发软化和/或保湿剂如甘油的量为组合物重量的约0.1％至约15％。组合物可以是洗剂或水包裹，并且可以在有或没有热的情况下使用。出乎意料的是，组合物不管头发的结构损伤如何，都适用于任何类型的头发，导致相同程度的卷曲紧度和柔软度，并且可以比现有技术的永久性波浪组合物更经常地应用而不会对头发造成显着的损害。

4. 发明授权

US5382426A Cysteamine permament wave composition and method 失效
标题翻译：半胱胺变形波组成及方法
公开(公告)号：US5382426A
公开(公告)日：1995-01-17
申请号：US096364
申请日：1993-07-22
申请人： Arun Nandagiri , Richard A. Abbott , Renee E. Nardone , Edward T. Borish
发明人： Arun Nandagiri , Richard A. Abbott , Renee E. Nardone , Edward T. Borish
IPC分类号： A61K8/00 , A45D2/12 , A45D7/04 , A61K20060101 , A61K8/34 , A61K8/39 , A61K8/46 , A61K8/86 , A61Q5/04 , A61Q5/12 , A61K7/06 , A61K7/11
CPC分类号： A61Q5/04 , A61K8/46
摘要： A single formula, mild permanent wave reducing composition and method of permanently waving or reshaping human hair that provides a strong, long lasting curl and leaves the hair soft while minimizing further damage to already damaged hair. The composition contains a cysteamine reducing agent compound selected from the group consisting of cysteamine, a cysteamine salt, and mixtures thereof. The cysteamine compound should be present in an amount of about 7.8% to about 9.0% by weight; and sufficient additional alkali, if necessary, to bring the pH of the composition to about 7.8 to about 8.5. Optionally, a hair softening and/or moisturizing agent, such as glycerine is included in the composition in an amount of about 0.1% to about 15% by weight of the composition.
摘要翻译：一种单一的配方，温和的永久性波浪减少组合物和永久挥发或重塑人类头发的方法，提供强烈的，持久的卷曲，并使头发柔软，同时最大限度地减少已损坏的头发的进一步损伤。该组合物含有选自半胱胺，半胱胺盐及其混合物的半胱胺还原剂化合物。半胱胺化合物的存在量应为约7.8％至约9.0％重量; 并且如果需要，足够的另外的碱使组合物的pH达到约7.8至约8.5。任选地，组合物中包含头发软化和/或保湿剂如甘油的量为组合物重量的约0.1％至约15％。

5. 发明授权

US5362486A In-situ polymerization of oligomers onto hair 失效
标题翻译：低聚物在头发上的原位聚合
公开(公告)号：US5362486A
公开(公告)日：1994-11-08
申请号：US866844
申请日：1992-04-10
申请人： Arun Nandagiri , Jacqueline Hutter , Ramiro Galleguillos
发明人： Arun Nandagiri , Jacqueline Hutter , Ramiro Galleguillos
IPC分类号： A61K31/765 , C08G18/10 , C08G18/67 , A61K7/11 , C08G18/04
CPC分类号： A61K8/87 , A61Q5/04 , C08G18/10 , C08G18/672 , A61K2800/95 , Y10S424/01 , Y10S424/02
摘要： An aqueous, alcoholic or hydroalcholic composition containing one or more oligomers or prepolymers that are polymerized in-situ, while the oligomer(s) is in contact with the hair, for in-situ formation (polymerization) of a polymer. The oligomer compositions contain essentially no toxic, hazardous or harmful monomer(s), such as resorcinol. In-situ polymerization provides substantially increased body to the hair; provides better, more continuous films of polymer into and onto the hair; provides a polymer coating with less flaking; will provide a more complete bond to adjacent hair shafts and to each individual hair shaft; better protects the hair against uptake of humidity; strengthens damaged hair; resists removal through at least three shampoos; are useful together with permanent wave reducing and oxidizing agents to make permanent waves more durable; prevents leach out of hair colors; provides for higher loading of polymer into and onto the hair and, therefore, better set retention; and provides a more durable set retention that also protects the hair against thermal damage and better resists hair uptake of atmospheric contaminants. When the polymerization of the oligomer or prepolymer results in a thermoplastic polymer having a glass transition temperature (T.sub.g) less than about 120.degree. C., the polymer can be repeatedly heated and cooled to reset the hair many times to reconfigure the hair without degrading the polymer.
摘要翻译：含有一种或多种低聚物或预聚物的水性，醇类或水溶性组合物，其在低聚物与毛发接触的同时原位聚合，用于聚合物的原位形成（聚合）。低聚物组合物基本上不含有毒的，有害的或有害的单体，例如间苯二酚。原位聚合为头发提供了显着增加的身体; 提供更好，更连续的聚合物薄膜到头发上和上，提供具有较少剥落的聚合物涂层; 将为相邻的发根和每个单独的毛发提供更完整的粘合; 更好地保护头发免受吸湿; 加强受损的头发; 通过至少三种洗发剂抵抗去除; 与永久性波浪还原和氧化剂一起使用，使永久性波浪更耐用; 防止脱出头发的颜色; 提供聚合物进入头发和/或头发上的较高载量，因此更好地设定保持力; 并提供更耐用的凝固保持，也保护头发免受热损伤，并更好地抵抗大气污染物的毛发吸收。当低聚物或预聚物的聚合导致玻璃化转变温度（Tg）小于约120℃的热塑性聚合物时，聚合物可被反复加热和冷却以使头发多次重新配置以重新配置头发而不会降解聚合物。

6. 发明授权

US5000948A Film release of hair-treating compositions 失效
标题翻译：毛发处理组合物的膜释放
公开(公告)号：US5000948A
公开(公告)日：1991-03-19
申请号：US369439
申请日：1989-06-20
申请人： Arun Nandagiri , Joseph C. Hourihan , Kathy Pilko , Alice B. Benson
发明人： Arun Nandagiri , Joseph C. Hourihan , Kathy Pilko , Alice B. Benson
IPC分类号： A45D7/04 , A61K8/02 , A61K8/23 , A61Q5/04
CPC分类号： A61Q5/04 , A45D7/04 , A61K8/0208 , A61K8/23
摘要： A hair-waving product comprises a polyurethane film containing a hair-waving composition which is released from the polyurethane film when the film is contacted with wet hair. The invention also relates to a process of hair waving comprising rolling the polyurethane film into wet hair and allowing sufficient hair-waving treatment time to release the hair-waving composition.
摘要翻译：吹发产品包括含有挥发性组合物的聚氨酯膜，当该薄膜与湿毛发接触时，该发泡组合物从聚氨酯膜中释放出来。本发明还涉及一种头发挥发的方法，其包括将聚氨酯薄膜卷入湿毛发中，并允许足够的烫发处理时间以释放发烫组合物。

7. 发明授权

US5554363A Method of reducing malodors in permanent waving 失效
标题翻译：减少永久挥舞中恶臭的方法
公开(公告)号：US5554363A
公开(公告)日：1996-09-10
申请号：US371353
申请日：1995-01-11
申请人： Arun Nandagiri , Bruce H. Solka , John A. Kocis
发明人： Arun Nandagiri , Bruce H. Solka , John A. Kocis
IPC分类号： A61K8/33 , A61Q5/04 , A61Q15/00 , A61K7/09
CPC分类号： A61Q5/04 , A61K8/33 , A61Q15/00
摘要： A method of treating hair to reduce post-perm odor by (1) reducing the degree of reaction between a permanent wave reducing agent and a natural compound contained in hair, e.g., hair aldehydes; and/or (2) altering the malodor of products formed by the reaction of hair and a permanent wave reducing agent, during the oxidation step; and/or (3) binding a fragrance to the hair to mask any odoriferous compounds that result from reaction of a reducing agent with the hair, or from the reaction of reduced hair with an oxidizing agent; and/or (4) change the naturally occurring post-perm odor by adding a reducing agent reactant during the permanent waving process resulting in more pleasant smelling reaction products.
摘要翻译：（1）降低烫发剂与包含在头发中的天然化合物例如毛发醛之间的反应程度的方法来治疗头发以减少烫发后的气味; 和/或（2）在氧化步骤期间改变由毛发和永久性挥发还原剂的反应形成的产物的恶臭; 和/或（3）将香料与头发结合以掩蔽由还原剂与毛发的反应或由还原的毛发与氧化剂的反应产生的任何有气味的化合物; 和/或（4）通过在永久性挥发过程中加入还原剂反应物来改变天然发生的烫发后气味，从而产生更令人愉快的嗅觉反应产物。

8. 发明授权

US5456907A Cysteamine permanent wave composition and method 失效
标题翻译：半胱胺永久性波浪组成及方法
公开(公告)号：US5456907A
公开(公告)日：1995-10-10
申请号：US186808
申请日：1994-01-25
申请人： Arun Nandagiri , Richard A. Abbott , Renee E. Nardone , Edward T. Borish
发明人： Arun Nandagiri , Richard A. Abbott , Renee E. Nardone , Edward T. Borish
IPC分类号： A45D2/12 , A45D7/04 , A61K8/46 , A61Q5/04 , A61K7/06 , A61K7/11
CPC分类号： A61K8/46 , A61Q5/04
摘要： A single formula, mild permanent wave reducing composition and method of permanently waving or reshaping human hair that provides a strong, long lasting curl and leaves the hair soft while minimizing further damage to already damaged hair. The composition contains a cysteamine reducing agent compound selected from the group consisting of cysteamine, a cysteamine salt, and mixtures thereof. The cysteamine compound should be present in an amount of at least about 7.8% by weight and preferably in the range of about 7.8% to about 12.5% by weight; and sufficient additional alkali, if necessary, to bring the pH of the composition to at least about 7.8 preferably about 7.8 to about 8.8. Optionally, a hair softening and/or moisturizing agent, such as glycerine is included in the composition in an amount of about 0.1% to about 15% by weight of the composition. The composition can be lotion or water wrapped and can be used with or without heat. Unexpectedly, the composition is applied to any type of hair, regardless of structural damage to the hair, resulting in the same degree of curl tightness and softness and can be applied much more frequently than prior art permanent wave compositions without significant damage to the hair.
摘要翻译：一种单一的配方，温和的永久性波浪减少组合物和永久挥发或重塑人类头发的方法，提供强烈的，持久的卷曲，并使头发柔软，同时最大限度地减少已损坏的头发的进一步损伤。该组合物含有选自半胱胺，半胱胺盐及其混合物的半胱胺还原剂化合物。半胱胺化合物的存在量应为至少约7.8重量％，优选约7.8重量％至约12.5重量％; 和足够的额外的碱，如果需要，使组合物的pH至少约7.8，优选约7.8至约8.8。任选地，组合物中包含头发软化和/或保湿剂如甘油的量为组合物重量的约0.1％至约15％。组合物可以是洗剂或水包裹，并且可以在有或没有热的情况下使用。出乎意料的是，组合物不管头发的结构损伤如何，都适用于任何类型的头发，导致相同程度的卷曲紧度和柔软度，并且可以比现有技术的永久性波浪组合物更加频繁地应用而不会对头发造成显着的损害。

9. 发明授权

US5260054A Cysteamine permanent wave composition and method 失效
标题翻译：半胱胺永久性波浪组成及方法
公开(公告)号：US5260054A
公开(公告)日：1993-11-09
申请号：US819113
申请日：1992-01-10
申请人： Arun Nandagiri , Richard A. Abbott , Renee E. Nardone
发明人： Arun Nandagiri , Richard A. Abbott , Renee E. Nardone
IPC分类号： A61K8/00 , A45D2/12 , A45D7/04 , A61K20060101 , A61K8/34 , A61K8/39 , A61K8/46 , A61K8/86 , A61Q5/04 , A61Q5/12 , A61K7/06 , A61K7/09 , A61K7/11
CPC分类号： A61Q5/04 , A61K8/46
摘要： A single formula, mild permanent wave reducing composition and method of permanently waving or reshaping human hair that provides a strong, long lasting curl and leaves the hair soft while minimizing further damage to already damaged hair. The composition contains a cysteamine reducing agent compound selected from the group consisting of cysteamine, a cysteamine salt, and mixtures thereof; preferably alone (without a monothioglycolate; a monothioglycolic acid ester, e.g., thioglycerol; a thiolactic acid; a sulfite; a hyposulfite, or a bisulfite second reducing agent). The cysteamine compound should be present in an amount of about 7.8% to about 9.0% by weight; and sufficient additional alkali, if necessary, to bring the pH of the composition to about 7.8 to about 8.5. Optionally, a hair softening and/or moisturizing agent, such as glycerine is included in the composition in an amount of about 0.1% to about 15% by weight of the composition. The composition can be lotion or water wrapped and can be used with or without heat. Unexpectedly, the composition is applied to any type of hair, regardless of structural damage to the hair, resulting in the same degree of curl tightness and softness and can be applied much more frequently than prior art permanent wave compositions without significant damage to the hair.

10. 发明授权

US5223252A Permanent wave composition and method 失效
标题翻译：永久波组成和方法
公开(公告)号：US5223252A
公开(公告)日：1993-06-29
申请号：US919972
申请日：1992-07-27
申请人： Stanley J. Kolc , Richard A. Abbott , Arun Nandagiri
发明人： Stanley J. Kolc , Richard A. Abbott , Arun Nandagiri
IPC分类号： A61K8/44 , A61K8/46 , A61Q5/04
CPC分类号： A61Q5/04 , A61K8/447 , A61K8/46
摘要： A mild, alkaline permanent wave reducing composition and method of permanently waving or reshaping human hair that provides a strong, long lasting curl like an alkaline permanent wave composition but leaves the hair soft like an acid permanent wave composition and leaves essentially no post-perm odor. The composition contains about 2.0% to about 6.5% by weight of a cysteine reducing agent compound selected from the group consisting of cysteine, a cysteine salt, and mixtures thereof; about 4.5% to about 8.0% of a thioglycolate; and sufficient additional alkali, if necessary, to bring the pH of the composition within the rang of about 7.5 to about 9.5.
摘要翻译：一种温和的碱性永久性波浪还原组合物和永久性挥发或重塑人类头发的方法，其提供如碱性永久性波浪组合物强烈且持久的卷曲，但是像酸性永久性波浪组合物那样使头发柔软，并且基本上没有烫发后味。该组合物含有约2.0％至约6.5％重量的半胱氨酸还原剂化合物，其选自半胱氨酸，半胱氨酸盐及其混合物; 约4.5％至约8.0％的巯基乙酸酯; 并且如果需要，足够的另外的碱使组合物的pH达到约7.5至约9.5。

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