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1. 发明专利

JP2015033634A 粘膜下医療処置を実行するための方法及びシステム有权
标题翻译：用于执行基层医疗程序的方法和系统
公开(公告)号：JP2015033634A
公开(公告)日：2015-02-19
申请号：JP2014217483
申请日：2014-10-24
申请人：アポロエンドサージェリー,インコーポレイティド , Apollo Endosurgery Inc , アポロエンドサージェリー,インコーポレイティド , ザ・ボード・オブ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・テキサス・システムThe Board Of Regents Of The University Of Texas System , Board Of Regents Of The Univ Of Texas System , ザ・ボード・オブ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・テキサス・システムThe Board Of Regents Of The University Of Texas System
发明人： VLADIMIR MITELBERG , DONALD K JONES , YUAN DAVID Y , BRETT E NAGLREITER , J LANDON GILKEY , CHRISTOPHER J GOSTOUT , PANKAJ J PASRICHA
IPC分类号： A61M25/10 , A61M5/14 , A61M5/32
CPC分类号： A61B17/320783 , A61B10/0283 , A61B17/22031 , A61B17/32056 , A61B17/3478 , A61B18/1477 , A61B18/1492 , A61B18/22 , A61B2017/00269 , A61B2017/00539 , A61B2017/2937 , A61B2017/320048 , A61B2018/00291 , A61B2018/1407 , A61B2018/1425
摘要：【課題】哺乳動物の粘膜下層内にトンネルを作成するための医療器具を提供する。【解決手段】医療器具は、近位及び遠位端とそれを通って延びるルーメンとを有する伸長管状部材と、近位及び遠位端を有する拡張可能部材であって、拡張可能部材の近位端は管状部材の遠位端に取り付けられ、拡張可能部材の遠位端は裏返されて管状部材のルーメン内に配置されるような、拡張可能部材とを有し、伸長管状部材の遠位端は、粘膜層を介して開口部に入り、哺乳動物の粘膜下層内に進入するように形成される。【選択図】図14
摘要翻译：要解决的问题：提供一种用于在哺乳动物的粘膜下层中形成隧道的医疗器械。解决方案：医疗器械包括细长管状构件，其具有近端和远端以及延伸穿过其中的内腔，以及可扩张构件，远端，其中可扩张构件的近端附接到管状构件的远端，并且可扩张构件的远端被转动并定位在管状构件的内腔内。管状构件的远端通过粘膜进入开口并进入哺乳动物的粘膜下层。

2. 发明专利

JP2014193372A Endoscopic suturing system 有权
标题翻译：内窥镜系统
公开(公告)号：JP2014193372A
公开(公告)日：2014-10-09
申请号：JP2014095799
申请日：2014-05-07
申请人： Apollo Endosurgery Inc , アポロエンドサージェリー,インコーポレイティド
发明人： J LANDON GILKEY , DONALD K JONES , KRATSCH PETER K , BRETT E NAGLREITER
IPC分类号： A61B17/04 , A61B17/06
CPC分类号： A61B17/0469 , A61B1/018 , A61B17/00234 , A61B17/0487 , A61B17/06123 , A61B17/0625 , A61B17/068 , A61B2017/00296 , A61B2017/00349 , A61B2017/0417 , A61B2017/0464 , A61B2017/0496 , A61B2017/06047 , A61B2017/0608 , A61B2017/0649 , A61B2017/2912
摘要： PROBLEM TO BE SOLVED: To provide an endoscopic surgical device having a structure enabling a small profile for delivery while providing both a large opening and closing angle and producing a large needle force for piercing tissue to perform a surgical operation such as tissue approximation and suturing within the body.SOLUTION: Disclosed are an endoscopic suturing system 10 and a method for endoscopic suturing, and devices for use with the system and the method such as a suture dispenser, a cinch device, and a tissue grasper. In one embodiment, the suturing system includes a cap assembly arranged at the distal end portion of an endoscope 12 or guide member, the cap assembly including a rotatable needle holder. The needle holder is actuated through a transmission element extending outside the endoscope 12 or guide member. A needle capture device may be inserted into a channel of the endoscope or guide member in order to capture a needle held in the needle holder when the needle holder is rotated so that the needle punctures tissue.
摘要翻译：要解决的问题：提供一种内窥镜手术装置，其具有能够提供小轮廓的结构，同时提供大的打开和关闭角度并且产生用于刺穿组织的大的针力以执行例如组织近似和缝合的外科手术身体。解决方案：公开了一种内窥镜缝合系统10和内窥镜缝合方法，以及用于该系统的装置和诸如缝线分配器，束带装置和组织夹紧器的方法。在一个实施例中，缝合系统包括布置在内窥镜12或引导构件的远端部分处的帽组件，帽组件包括可旋转的针保持器。针保持器通过延伸到内窥镜12或引导构件外部的传动元件致动。针捕获装置可以插入内窥镜或引导构件的通道中，以便当针保持器旋转时捕获保持在针保持器中的针，使得针刺穿组织。

3. 发明申请

WO2017075309A4 ENDOSCOPIC SUTURE LOOP ANCHORS AND METHODS 审中-公开
标题翻译：内窥镜缝合环锚钉和方法
公开(公告)号：WO2017075309A4
公开(公告)日：2017-06-22
申请号：PCT/US2016059256
申请日：2016-10-28
申请人： APOLLO ENDOSURGERY INC
发明人： MIMS JOHN , DEAN CHARLES , PINTO NICOLE , GILKEY MITCHELL , MITELBERG VLADIMIR , JONES DONALD K
IPC分类号： A61B17/062 , A61B17/94
CPC分类号： A61B17/0469 , A61B17/0482 , A61B17/0485 , A61B17/06061 , A61B17/06109 , A61B17/06166 , A61B17/29 , A61B2017/00004 , A61B2017/00818 , A61B2017/0472 , A61B2017/0496 , A61B2017/06052 , A61B2017/06176 , A61F5/0089
摘要： A suture needle system includes a first needle and at least one second needle. Each of the first and second needles preferably has a common needle body construct. The first needle includes an elongate suture having a length sufficient to extend at least the length of an instrument channel of an endoscope. The second needle includes an opening formed by a loop of suture at which the second needle can be advanced over the elongate suture. In use, the first needle is secured to a first tissue location using an endoscopic suturing system. A second needle is advanced at its opening over the elongate suture and secured to a second tissue location. Additional second needles may be advanced over the elongate suture to respective tissue locations. The elongate suture is pulled taut, drawing the second needles into proximity, and secured.
摘要翻译：缝合针系统包括第一针和至少一个第二针。第一和第二针中的每一个优选具有共同的针体构造。第一针包括具有足以至少延伸内窥镜的器械通道的长度的长度的细长缝合线。第二针包括由缝合线环形成的开口，在缝合线处第二针可以在细长缝合线上前进。在使用中，使用内窥镜缝合系统将第一针固定到第一组织位置。第二根针在细长缝合线上的开口处前进并固定到第二组织位置。另外的第二针可以在细长缝合线上推进至相应的组织位置。将拉长的缝线拉紧，将第二根针拉近，并固定。

4. 发明申请

WO2012154648A1 ENDOSCOPIC SUTURING SYSTEM 审中-公开
标题翻译：内窥镜系统
公开(公告)号：WO2012154648A1
公开(公告)日：2012-11-15
申请号：PCT/US2012/036740
申请日：2012-05-07
申请人： APOLLO ENDOSURGERY, INC. , MITELBERG, Vladimir
发明人： MITELBERG, Vladimir
IPC分类号： A61B17/04
CPC分类号： A61B17/0625 , A61B1/00087 , A61B1/00089 , A61B1/00094 , A61B1/00101 , A61B1/00137 , A61B1/018 , A61B1/04 , A61B17/00234 , A61B17/0401 , A61B17/0487 , A61B17/06123 , A61B17/06133 , A61B17/068 , A61B50/13 , A61B2017/00296 , A61B2017/00349 , A61B2017/0042 , A61B2017/00477 , A61B2017/0409 , A61B2017/0417 , A61B2017/0454 , A61B2017/0464 , A61B2017/0496 , A61B2017/06047 , A61B2017/06052 , A61B2017/0608 , A61B2017/0649 , A61B2017/2912
摘要： A treatment device for use with an endoscope having a instrument channel for passage of an endoscopic instrument and a distal end is provided. The treatment device includes an end effector assembly with a base for placement at the distal end of the endoscope, an end effector rotatable relative to the base, and a mounting portion for attaching the base to the endoscope. The mounting portion is resiliently compressible and can be radially compressed for insertion into the instrument channel, whereby an expansion force of the resiliently compressed mounting portion retains the base relative to the distal end of the endoscope. The mounting portion also includes an opening longitudinally extending therethrough and communicable with the instrument chann 1 and sized for receiving an endoscopic instrument therethrough.
摘要翻译：提供了一种用于具有用于内窥镜器械和远端通过的器械通道的内窥镜的治疗装置。治疗装置包括端部执行器组件，其具有用于放置在内窥镜的远端的基部，相对于基部可旋转的末端执行器，以及用于将基部附接到内窥镜的安装部。安装部分是可弹性压缩的并且可以被径向压缩以插入到器械通道中，由此弹性压缩的安装部分的膨胀力相对于内窥镜的远端保持基部。安装部分还包括纵向延伸穿过其中并与仪器通道1可连接的开口，并且其尺寸用于容纳通过其中的内窥镜器械。

5. 发明申请

WO2009009274A3 METHODS AND SYSTEMS FOR PERFORMING SUBMUCOSAL MEDICAL PROCEDURES 审中-公开
公开(公告)号：WO2009009274A3
公开(公告)日：2009-01-15
申请号：PCT/US2008/067635
申请日：2008-06-20
申请人： APOLLO ENDOSURGERY, INC. , THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM , MITELBERG, Vladimir , JONES, Donald, K. , YUAN, David, Y. , NAGLREITER, Brett, E. , GILKEY, J., Landon , GOSTOUT, Christopher, J. , PASRICHA, Pankaj, J.
发明人： MITELBERG, Vladimir , JONES, Donald, K. , YUAN, David, Y. , NAGLREITER, Brett, E. , GILKEY, J., Landon , GOSTOUT, Christopher, J. , PASRICHA, Pankaj, J.
IPC分类号： A61B17/24
摘要： Instruments, systems and methods are provided for performing submucosal medical procedures in a desired area of the digestive tract using endoscopy. Instruments include a safe access needle injection instrument, a submucosal tunneling instrument, a submucosal dissection instrument, a mucosal resection device. Systems include a combination of one or more of such instruments with or without injectable agents. Embodiments of various methods for performing the procedures are also provided.

6. 发明申请

WO2009009274A2 METHODS AND SYSTEMS FOR PERFORMING SUBMUCOSAL MEDICAL PROCEDURES 审中-公开
标题翻译：用于执行子宫内膜医疗程序的方法和系统
公开(公告)号：WO2009009274A2
公开(公告)日：2009-01-15
申请号：PCT/US2008067635
申请日：2008-06-20
申请人： APOLLO ENDOSURGERY INC , UNIV TEXAS , MITELBERG VLADIMIR , JONES DONALD K , YUAN DAVID Y , NAGLREITER BRETT E , GILKEY J LANDON , GOSTOUT CHRISTOPHER J , PASRICHA PANKAJ J
发明人： MITELBERG VLADIMIR , JONES DONALD K , YUAN DAVID Y , NAGLREITER BRETT E , GILKEY J LANDON , GOSTOUT CHRISTOPHER J , PASRICHA PANKAJ J
IPC分类号： A61B17/94 , A61N1/02
CPC分类号： A61B17/320783 , A61B10/0283 , A61B17/22031 , A61B17/32056 , A61B17/3478 , A61B18/1477 , A61B18/1492 , A61B18/22 , A61B2017/00269 , A61B2017/00539 , A61B2017/2937 , A61B2017/320048 , A61B2018/00291 , A61B2018/1407 , A61B2018/1425
摘要： Instruments, systems and methods are provided for performing submucosal medical procedures in a desired area of the digestive tract using endoscopy. Instruments include a safe access needle injection instrument, a submucosal tunneling instrument, a submucosal dissection instrument, a mucosal resection device. Systems include a combination of one or more of such instruments with or without injectable agents. Embodiments of various methods for performing the procedures are also provided.
摘要翻译：提供仪器，系统和方法用于使用内窥镜在消化道的期望区域执行粘膜下医学操作。器械包括安全进入针头注射器械，粘膜下隧道器械，粘膜下剥离器械，粘膜切除器械。系统包括一个或多个这种仪器的组合，有或没有注射剂。还提供了用于执行程序的各种方法的实施例。

7. 发明申请

WO2014055766A1 INTRAGASTRIC BALLOON FOR TREATING OBESITY 审中-公开
标题翻译：用于治疗肥胖的腹水
公开(公告)号：WO2014055766A1
公开(公告)日：2014-04-10
申请号：PCT/US2013/063276
申请日：2013-10-03
申请人： APOLLO ENDOSURGERY, INC.
发明人： SCHWAB, Justin, J. , DOMINGUEZ, Zachary, P. , RAVEN, Joseph, S. , BABKES, Mitchell, H. , MUDD, Christopher, S. , BERTOLOTE, Tiago
IPC分类号： A61F5/00
CPC分类号： A61F5/003 , A61F5/0036
摘要： A transorally implanted intragastric balloon or treating obesity and for weight control including a variable size balloon with one or interconnected regions acting to exert a pressure on the stomach, to provide a stomach volume occupying effect, and/or to anchor the balloon within the stomach.
摘要翻译：经胃内植入的胃内球囊或治疗肥胖症并且用于体重控制，包括具有一个或相互连接的区域作用以对胃施加压力的可变大小的球囊，以提供胃体积占据效果，和/或将囊固定在胃内。

8. 发明申请

WO2014014715A1 ENDOSCOPE OVERTUBE FOR NATURAL BODY ORIFICE INSERTION 审中-公开
标题翻译：用于自然身体插入的内窥镜超声波
公开(公告)号：WO2014014715A1
公开(公告)日：2014-01-23
申请号：PCT/US2013/049830
申请日：2013-07-10
申请人： APOLLO ENDOSURGERY, INC.
发明人： WEST, Stephen
IPC分类号： A61B1/273 , A61B1/24 , A61B1/31 , A61B1/00 , A61B19/00 , A61B1/313
CPC分类号： A61B1/00135 , A61B1/00128 , A61B1/0014 , A61B1/12 , A61B1/2736 , A61B17/3415 , A61B17/3439 , A61B17/3462 , A61B2017/345 , A61B2017/347 , A61M39/0613 , A61M39/228 , A61M2039/0673 , F04C2270/041 , G02B23/2476
摘要： An endoscope overtube includes a flexible tubular member and a hub assembly provided at the proximal end of the tubular member. The hub assembly includes an elastic sleeve seal cuff extending about the inner surface of a body member of the hub. The ends of seal cuff are coupled to the body member. An inflation line extends into the body member in communication with the outer surface of the seal cuff. When fluid is pressurized through the inflation line, the cuff is distended inward to reduce the size of the opening through the port such that the cuff forms a seal about an endoscope received through the hub. The body member is preferably coupled to each of the flexible tubular member and to the elastic seal cuff using a snap-fit engagement of parts such that no fasteners, welds, glues, etc. are necessary for securing the hub assembly together.
摘要翻译：内窥镜套管包括柔性管状构件和设置在管状构件的近端处的轮毂组件。毂组件包括围绕毂的主体构件的内表面延伸的弹性套筒密封箍。密封箍的端部联接到主体构件。充气线延伸到与密封箍的外表面连通的主体部件中。当流体通过充气管线加压时，袖带向内扩张以减小通过端口的开口的尺寸，使得袖带围绕通过轮毂接收的内窥镜形成密封。本体构件优选地使用部件的卡扣配合接合到每个柔性管状构件和弹性密封箍，使得不需要紧固件，焊缝，胶水等来将轮毂组件固定在一起。

9. 发明申请

WO2009155287A1 ENDOSCOPIC SUTURING SYSTEM 审中-公开
标题翻译：内窥镜系统
公开(公告)号：WO2009155287A1
公开(公告)日：2009-12-23
申请号：PCT/US2009/047508
申请日：2009-06-16
申请人： APOLLO ENDOSURGERY, INC. , GILKEY, J., Landon , JONES, Donald, K. , KRATSCH, Peter, K. , NAGLREITER, Brett, E.
发明人： GILKEY, J., Landon , JONES, Donald, K. , KRATSCH, Peter, K. , NAGLREITER, Brett, E.
IPC分类号： A61B17/04 , A61B1/04 , A61B1/00
CPC分类号： A61B17/0469 , A61B1/018 , A61B17/00234 , A61B17/0487 , A61B17/06123 , A61B17/0625 , A61B17/068 , A61B2017/00296 , A61B2017/00349 , A61B2017/0417 , A61B2017/0464 , A61B2017/0496 , A61B2017/06047 , A61B2017/0608 , A61B2017/0649 , A61B2017/2912
摘要： An endoscopic suturing system and method are disclosed as are devices for use with the system and method such as a suture dispenser, a cinch device, and a tissue grasper. In one embodiment the suturing system includes a cap assembly arranged at the distal end portion of an endoscope or guide member, with the cap assembly including a rotatable needle holder. The needle holder is actuated through a transmission element extending outside the endoscope or guide member. A needle capture device may be inserted through a channel of the endoscope or guide member in order to capture a needle held in the needle holder when the needle holder is rotated so that the needle punctures tissue.
摘要翻译：公开了内窥镜缝合系统和方法，用于与系统和方法一起使用的装置，例如缝合分配器，束带装置和组织抓紧器。在一个实施例中，缝合系统包括布置在内窥镜或引导构件的远端部分处的帽组件，帽组件包括可旋转的针保持器。针保持器通过延伸到内窥镜或引导构件外部的传动元件致动。可以通过内窥镜或引导构件的通道插入针捕获装置，以便当针保持器旋转时捕获保持在针保持器中的针，使得针刺穿组织。

10. 发明申请

WO2014164955A2 ENDOSCOPIC SUTURE CINCH SYSTEM WITH REPLACEABLE CINCH 审中-公开
标题翻译：具有可更换的内脏的内窥镜切割系统
公开(公告)号：WO2014164955A2
公开(公告)日：2014-10-09
申请号：PCT/US2014/023906
申请日：2014-03-12
申请人： APOLLO ENDOSURGERY, INC.
发明人： MITELBERG, Vladimir
IPC分类号： A61B17/04 , A61B17/06
CPC分类号： A61B17/0487 , A61B17/0467 , A61B17/0469 , A61B17/0482 , A61B2017/0053 , A61B2017/0488
摘要： [0070] A suture cinch, cinch applicator, and cinch loader for loading the cinch into the cinch applicator are provided and permit re-use of the applicator with multiple cinches during an endoscopic procedure. The applicator can be loaded with a first cinch, apply the first cinch onto a portion of suture to fix the portion of suture relative to anatomical tissue, reloaded with a second cinch optionally using the loader, and subsequently used to apply the second cinch to fix another portion of suture to fix the other portion of suture relative to anatomical tissue. The cinch is a tubular member through which the suture can be advanced when the cinch is loaded within the applicator. The cinch defines multiple ribs and cutter defined in a wall thereof. Operation of the applicator deforms the ribs inward to retain the cinch on the suture, and displaces the cutter to sever the suture.
摘要翻译：提供了一种用于将束带装载到系带施放器中的缝合线束带，带状施肥器和系带装载器，并且允许在内窥镜过程期间使用具有多个系带的施用器。施加器可以装载有第一系带，将第一束带施加到缝合线的一部分上以相对于解剖组织固定缝合线的部分，可选地使用装载器重新加载第二束带，并随后用于施加第二束带以固定缝合线的另一部分以相对于解剖组织固定缝合线的另一部分。系带是一种管状构件，通过该管状构件，当将束带装载到施用器内时缝合线可以前进。系带限定了在其壁中限定的多个肋和切割器。施加器的操作使肋向内变形以将束带保持在缝合线上，并使切割器移位以切断缝合线。

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