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    • 8. 发明授权
    • Avermectins substituted in the 4″-position having pesticidal properties
    • 在4“位置取代的阿维菌素具有杀虫特性
    • US07732416B2
    • 2010-06-08
    • US11319686
    • 2005-12-28
    • Thomas PitternaAnthony Cornelius O'SullivanWilliam Lutz
    • Thomas PitternaAnthony Cornelius O'SullivanWilliam Lutz
    • A61K31/70C07H17/08
    • C07H19/01A01N43/90A01N47/12A01N47/14A01N47/28A01N47/30A01N47/32
    • What is described are a compound of the formula in which R1 is C1-C12alkyl, C3-C8cycloalkyl or C2-C12alkenyl; R2 is H, unsubstituted or mono- to pentasubstituted C1-C12alkyl or unsubstituted or mono- to pentasubstituted C1-C12alkenyl; R3 is C2-C12alkyl, mono- to pentasubstituted C1-C12alkyl, unsubstituted or mono- to pentasubstituted C1-C6alkoxy-C1-C6alkyl, unsubstituted or mono- to pentasubstituted C3-C12cycloalkyl, C2-C12alkenyl, C2-C12alkynyl; or R2 and R3 together are an alkylene or alkenylene bridge; with the proviso that R1 is not sec-butyl or isopropyl if R2 is H and R3 is 2-hydroxyethyl, isopropyl, n-octyl or benzyl; or, if appropriate, in E/Z isomer, an E/Z isomer mixture and/or a tautomer thereof; a process for preparing and using these compounds and their tautomers; pesticides whose active compound is selected from these compounds and their tautomers; and a process for preparing these compounds and compositions, and the use of these compounds and compositions.
    • 描述的是下式的化合物,其中R 1是C 1 -C 12烷基,C 3 -C 8环烷基或C 2 -C 12链烯基; R 2为H,未取代或单价至五价取代的C 1 -C 12烷基或未取代或单价至五价取代的C 1 -C 12烯基; R 3是C 2 -C 12烷基,未被取代的或被一或五取代的C 1 -C 6烷氧基-C 1 -C 6烷基,未取代的或一至五取代的C 3 -C 12环烷基,C 2 -C 12链烯基,C 2 -C 12炔基; 或者R 2和R 3一起是亚烷基或亚烯基桥; 条件是R1不是仲丁基或异丙基,如果R2是H,R3是2-羟乙基,异丙基,正辛基或苄基; 或者如果合适的话,在E / Z异构体中,E / Z异构体混合物和/或其互变异构体; 一种制备和使用这些化合物及其互变异构体的方法; 活性化合物选自这些化合物及其互变异构体的农药; 以及制备这些化合物和组合物的方法,以及这些化合物和组合物的用途。