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1. 发明申请

US20110250137A1 RADIOISOTOPE-LABELED LYSINE AND ORNITHINE DERIVATIVES, THEIR USE AND PROCESSES FOR THEIR PREPARATION 审中-公开
标题翻译：放射性标记的赖氨酸和异构衍生物，其使用及其制备方法
公开(公告)号：US20110250137A1
公开(公告)日：2011-10-13
申请号：US13132671
申请日：2009-11-26
申请人： Norman Koglin , Lutz Lehmann , Holger Siebeneicher , Andre Müller , Niels Böhnke
发明人： Norman Koglin , Lutz Lehmann , Holger Siebeneicher , Andre Müller , Niels Böhnke
IPC分类号： A61K51/04 , C07C227/14 , A61K31/198 , C07C271/22 , C07C269/06 , A61K31/27 , C07C309/66 , C07C303/02 , A61K31/255 , C07F7/02 , A61K31/695 , C07C247/12 , A61K31/655 , C07D209/48 , A61K31/4035 , A61P35/00 , A61P43/00 , C12Q1/02 , C07C229/26
CPC分类号： C07C309/66 , C07B59/001 , C07C309/73 , C07D295/14 , C07F7/1804
摘要： The invention relates to the compounds suitable for radiolabeling with a chelator free radioisotope and radiolabeled compounds of the general Formula I.Said compounds are ornithine or lysine derivatives.
摘要翻译：本发明涉及适于用无螯合剂的放射性同位素和通式I的放射性标记的化合物进行放射性标记的化合物。所述化合物是鸟氨酸或赖氨酸衍生物。

2. 发明授权

US07287449B2 Screwdriver with removable rod 有权
标题翻译：螺丝刀带可拆卸杆
公开(公告)号：US07287449B2
公开(公告)日：2007-10-30
申请号：US10522661
申请日：2003-07-21
申请人： Michael Abel , Andre Müller
发明人： Michael Abel , Andre Müller
IPC分类号： B25B23/16
CPC分类号： B25B23/0042 , Y10S279/906 , Y10T279/17752 , Y10T279/17786 , Y10T279/17794
摘要： Screwing tool (1) having a grip (2) and a shank (3), which is received removably in a cavity (4) open toward an end of the grip (2) and which at its free end has an actuating portion (5). The shank (3) is retained in a position of use such that it is fixed in terms of rotation on the grip, to avoid sliding in the axial direction, by a retaining element (14) associated with the grip (2). The retaining element (14) can be displaced into a removal position by displacement of an actuating member (6) in order for the shank to be removed from the grip (2). In a storage position, a large part of the shank (3) is located in the cavity (4), where it is held by a holding element (H). The holding element (H) is releasable, so that part of the shank (3) can be moved out.
摘要翻译：具有把手（2）和柄（3）的螺丝刀具（1）可移除地接收在朝向柄（2）的端部敞开的空腔（4）中，并且在其自由端具有致动部分（5））。柄（3）被保持在使用位置，使得其在手柄上以旋转方式固定，以避免通过与把手（2）相关联的保持元件（14）在轴向上滑动。通过致动构件（6）的位移，保持元件（14）可以移位到去除位置，以便将柄从手柄（2）移除。在存储位置，柄（3）的大部分位于空腔（4）中，在其中被保持元件（H）保持。保持元件（H）是可释放的，使得柄（3）的一部分能够移出。

3. 发明授权

US09017645B2 Homoglutamic acid derivatives 有权
标题翻译：谷氨酸衍生物
公开(公告)号：US09017645B2
公开(公告)日：2015-04-28
申请号：US13509062
申请日：2010-11-08
申请人： Heribert Schmitt-Willich , Niels Böhnke , Norman Koglin , Andre Müller , Mathias Berndt , Matthias Friebe , Lutz Lehmann
发明人： Heribert Schmitt-Willich , Niels Böhnke , Norman Koglin , Andre Müller , Mathias Berndt , Matthias Friebe , Lutz Lehmann
IPC分类号： A61B5/055 , C07C271/22 , A61K49/10 , A61K51/04 , C07B59/00 , C07C229/24 , C07C229/30 , C07C255/58
CPC分类号： C07C271/22 , A61K49/10 , A61K51/04 , A61K51/0402 , C07B59/001 , C07B2200/05 , C07C229/24 , C07C229/30 , C07C255/58
摘要： This invention relates to homoglutamic acid derivatives suitable for labeling or already labeled with 18F or 19F, methods of preparing such compounds, compositions comprising such compounds, kits comprising such compounds or compositions and uses of such compounds, compositions or kits for diagnostic imaging.
摘要翻译：本发明涉及适用于标记或已经用18F或19F标记的高谷氨酸衍生物，制备此类化合物的方法，包含这些化合物的组合物，包含这些化合物或组合物的试剂盒以及用于诊断成像的这些化合物，组合物或试剂盒的用途。

4. 发明申请

US20110160979A1 METHOD OF ESTIMATING THE MAXIMUM POWER GENERATION CAPACITY AND FOR CONTROLLING A SPECIFIED POWER RESERVE OF A SINGLE CYCLE OR COMBINED CYCLE GAS TURBINE POWER PLANT, AND A POWER GENERATING SYSTEM FOR USE WITH SAID METHOD 有权
标题翻译：估算最大发电能力和控制单循环或组合循环气体发电厂的指定功率储备的方法，以及使用方法的发电系统
公开(公告)号：US20110160979A1
公开(公告)日：2011-06-30
申请号：US12977523
申请日：2010-12-23
申请人： Eric Andre MÜLLER
发明人： Eric Andre MÜLLER
IPC分类号： F02C9/00
CPC分类号： F02C9/00 , F01D17/16 , F01K13/02 , F01K23/10 , F02C1/007 , F05D2270/301 , F05D2270/303 , F05D2270/44 , F22B1/1815 , G05B17/02 , Y02E20/16
摘要： An estimation unit can estimate, on a real-time basis, a maximum power generation capacity of a single cycle or combined cycle gas turbine power plant. For example, the actual power output and the maximum power generation capacity can be calculated relying on a mathematical process model. Subsequently, the calculated actual power output can be compared with the measured power output yielding a model-estimation error. Based on the model-estimation error, a correction signal can be deduced, to correct the calculated maximum power generation capacity. A controller can maintain a specified power reserve. The controller can use an estimate of the maximum power generation capacity as a reference, subtract a load offset, and apply the resulting signal as upper limit of the load set-point.
摘要翻译：估计单元可以实时地估计单个循环或联合循环燃气轮机发电厂的最大发电能力。例如，实际功率输出和最大发电量可以依赖于数学过程模型来计算。随后，将计算出的实际功率输出与测得的功率输出进行比较，产生模型估计误差。基于模型估计误差，可以推导出校正信号，以校正计算出的最大发电量。控制器可以保持指定的动力储备。控制器可以使用最大发电量的估计作为参考，减去负载偏移，并将结果信号作为负载设定点的上限。

5. 发明授权

US08620482B2 Method of estimating the maximum power generation capacity and for controlling a specified power reserve of a single cycle or combined cycle gas turbine power plant, and a power generating system for use with said method 有权
标题翻译：估计最大发电量和控制单个循环或联合循环燃气轮机发电厂的规定动力储备的方法，以及用于所述方法的发电系统
公开(公告)号：US08620482B2
公开(公告)日：2013-12-31
申请号：US12977523
申请日：2010-12-23
申请人： Eric Andre Müller
发明人： Eric Andre Müller
IPC分类号： G05D3/12 , G05D5/00 , G05D9/00 , G05D11/00 , G05D17/00
CPC分类号： F02C9/00 , F01D17/16 , F01K13/02 , F01K23/10 , F02C1/007 , F05D2270/301 , F05D2270/303 , F05D2270/44 , F22B1/1815 , G05B17/02 , Y02E20/16
摘要： An estimation unit can estimate, on a real-time basis, a maximum power generation capacity of a single cycle or combined cycle gas turbine power plant. For example, the actual power output and the maximum power generation capacity can be calculated relying on a mathematical process model. Subsequently, the calculated actual power output can be compared with the measured power output yielding a model-estimation error. Based on the model-estimation error, a correction signal can be deduced, to correct the calculated maximum power generation capacity. A controller can maintain a specified power reserve. The controller can use an estimate of the maximum power generation capacity as a reference, subtract a load offset, and apply the resulting signal as upper limit of the load set-point.
摘要翻译：估计单元可以实时地估计单个循环或联合循环燃气轮机发电厂的最大发电能力。例如，实际功率输出和最大发电量可以依赖于数学过程模型来计算。随后，将计算出的实际功率输出与测得的功率输出进行比较，产生模型估计误差。基于模型估计误差，可以推导出校正信号，以校正计算出的最大发电量。控制器可以保持指定的动力储备。控制器可以使用最大发电量的估计作为参考，减去负载偏移，并将结果信号作为负载设定点的上限。

6. 发明申请

US20130071327A1 HOMOGLUTAMIC ACID DERIVATIVES 有权
标题翻译：均质酸衍生物
公开(公告)号：US20130071327A1
公开(公告)日：2013-03-21
申请号：US13509062
申请日：2010-11-08
申请人： Heribert Schmitt-Willich , Niels Böhnke , Norman Koglin , Andre Müller , Mathias Berndt , Matthias Friebe , Lutz Lehmann
发明人： Heribert Schmitt-Willich , Niels Böhnke , Norman Koglin , Andre Müller , Mathias Berndt , Matthias Friebe , Lutz Lehmann
IPC分类号： C07C229/24 , C07C255/59 , C07C271/22 , C07C309/73 , C07C269/06 , C07C227/00 , C07C253/00 , C07C269/00 , C07C227/20 , C07C253/30 , C07C229/30 , A61K51/04
CPC分类号： C07C271/22 , A61K49/10 , A61K51/04 , A61K51/0402 , C07B59/001 , C07B2200/05 , C07C229/24 , C07C229/30 , C07C255/58
摘要： This invention relates to homoglutamic acid derivatives suitable for labeling or already labeled with 18F or 19F, methods of preparing such compounds, compositions comprising such compounds, kits comprising such compounds or compositions and uses of such compounds, compositions or kits for diagnostic imaging.
摘要翻译：本发明涉及适于标记或已经用18F或19F标记的高谷氨酸衍生物，制备此类化合物的方法，包含这些化合物的组合物，包含这些化合物或组合物的试剂盒以及用于诊断成像的这些化合物，组合物或试剂盒的用途。

7. 发明申请

US20130034497A1 IODINE-LABELED HOMOGLUTAMIC ACID AND GLUTAMIC ACID DERIVATIVES 审中-公开
标题翻译：碘标记的酪氨酸和谷氨酸衍生物
公开(公告)号：US20130034497A1
公开(公告)日：2013-02-07
申请号：US13510359
申请日：2010-11-15
申请人： Heribert Schmitt-Willich , Niels Böhnke , Norman Koglin , Andre Müller , Holger Siebeneicher , Matthias Friebe
发明人： Heribert Schmitt-Willich , Niels Böhnke , Norman Koglin , Andre Müller , Holger Siebeneicher , Matthias Friebe
IPC分类号： C07C229/28 , A61K35/00 , A61K51/04 , A61K31/195 , C07F7/22
CPC分类号： C07C229/36 , C07B59/001 , C07B2200/05 , C07C229/24 , C07C233/81 , C07C271/22
摘要： This invention relates to derivatives of Iodine-labeled homoglutamic acids and glutamic acids and their analogues suitable for labeling or already labeled by Iodine, methods of preparing such compounds, compositions comprising such compounds, kits comprising such compounds or compositions and uses of such compounds, compositions or kits for diagnostic imaging or radiotherapy.
摘要翻译：本发明涉及碘标记的高谷氨酸和谷氨酸及其类似物的衍生物，其适用于标记或已经由碘标记的碘，制备此类化合物的方法，包含这些化合物的组合物，包含这些化合物或组合物的试剂和这些化合物的用途，组合物或用于诊断成像或放射治疗的试剂盒。

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