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1. 发明申请

US20060153435A1 Method and means for 2d-gel-image segmentation 审中-公开
标题翻译：二维凝胶图像分割的方法和手段
公开(公告)号：US20060153435A1
公开(公告)日：2006-07-13
申请号：US10516800
申请日：2003-06-19
申请人： Gustav Wallmark , Anders Heyden , Andreas Karlsson , Ola Frosstrom-Olsson
发明人： Gustav Wallmark , Anders Heyden , Andreas Karlsson , Ola Frosstrom-Olsson
IPC分类号： G06E3/00
CPC分类号： G06T7/0012 , G06K9/0014 , G06K9/34 , G06T7/11 , G06T7/187 , G06T7/64 , G06T2207/10056 , G06T2207/30024
摘要： The present invention relates to the segmentation of two-dimensional gel electrophoresis images (2D images). The method according to the invention associates an initial protein seed candidate with an interface circumscribing said seed and thereafter brings said interface to evolve in accordance with a defined speed function F(x, y). The evolution of the interface is halted by a stopping criterion, C. According to the invention, the speed function can depend on a wide variety of parameters such as the pixel intensity, the curvature of the pixel intensity, the distance to the initial seed, the curvature and/or shape and/or normal direction and/or position of the evolving interface. The stopping criterion depends e.g. on the speed function F and/or the time of arrival T(x, y) and/or the departure time Td for said interface. The invention provides criteria for a specific treatment of saturated spots and to mike sure that interfaces never overlap.
摘要翻译：本发明涉及二维凝胶电泳图像（2D图像）的分割。根据本发明的方法将初始蛋白质种子候选物与限定所述种子的界面相关联，然后使所述界面根据定义的速度函数F（x，y）进行演化。接口的演变由停止标准C停止。根据本发明，速度函数可以取决于各种各样的参数，例如像素强度，像素强度的曲率，到初始种子的距离，演变界面的曲率和/或形状和/或法线方向和/或位置。停止标准取决于对于所述接口，速度函数F和/或到达时间T（x，y）和/或出发时间T 。本发明提供了对饱和斑点的具体处理的标准，并确保界面不重叠。

2. 发明申请

US20050063574A1 Method and computer program for digital image processing for two-dimensional electrophoresis 审中-公开
标题翻译：用于二维电泳数字图像处理的方法和计算机程序
公开(公告)号：US20050063574A1
公开(公告)日：2005-03-24
申请号：US10500985
申请日：2003-01-10
申请人： Anders Heyden , Lars Malmstrom , Johan Malmstrom , Ola Forsstrom-Olsson , Magnus Berglund
发明人： Anders Heyden , Lars Malmstrom , Johan Malmstrom , Ola Forsstrom-Olsson , Magnus Berglund
IPC分类号： G01N27/447 , G06K9/00 , G06K9/32
CPC分类号： G01N27/44721 , G01N27/44773
摘要： Method for processing digital image data for a two-dimensional array of sample substance spots and marker substance spots in an electrophoresis gel by using landmark substances having predefined properties, comprising the steps of:generating an ideal image represented by co-ordinate data corresponding to ideal positions of the marker substance spots in said array dependent on electrophoresis conditions; generating a marker image represented by co-ordinate data corresponding to detected positions of said marker substances spots in the array; determining a mathematical relation between the ideal image and the marker image, such that the co-ordinate data of said images are mapped onto each other; generating a sample image represented by a sample image data set corresponding to detected signal values in the gel; and normalising the sample image by transforming it dependent on said mathematical relation.
摘要翻译：用于通过使用具有预定属性的地标物质来处理电泳凝胶中的样品物质斑点和标记物斑点的二维阵列的数字图像数据的方法，包括以下步骤：产生由对应于理想的坐标数据表示的理想图像所述阵列中标记物质斑点的位置取决于电泳条件; 产生由对应于阵列中的所述标记物质斑点的检测位置的坐标数据表示的标记图像; 确定理想图像和标记图像之间的数学关系，使得所述图像的坐标数据彼此映射; 产生由与凝胶中检测到的信号值对应的样本图像数据集表示的样本图像; 并且根据所述数学关系通过对样本图像进行变换来归一化样本图像。

3. 发明授权

US06268611B1 Feature-free registration of dissimilar images using a robust similarity metric 有权
标题翻译：使用强大的相似性指标对不同图像进行无特征的注册
公开(公告)号：US06268611B1
公开(公告)日：2001-07-31
申请号：US09212730
申请日：1998-12-16
申请人： Magnus Pettersson , Anders Rosenqvist , Anders Heyden , Martin Almers
发明人： Magnus Pettersson , Anders Rosenqvist , Anders Heyden , Martin Almers
IPC分类号： G01N2186
CPC分类号： G06T3/0075 , G02B21/244 , G06T3/403
摘要： An image registration (alignment) system which achieves alignment by determining an optimal focus for a composite image produced from the combination of misregistered images. The system also uses optimal or nearly optimal linear filters for filtering the combined image to emphasize (enhance) alignment information in the combined image and to de-emphasize (damp) noise. One set of the nearly optimal linear filters are modified second order difference filters in which the number of internal zeros are modified to tune the filter to the particular equipment.
摘要翻译：一种图像配准（对准）系统，其通过确定由未记录图像的组合产生的合成图像的最佳焦点来实现对准。该系统还使用最佳或近似最优的线性滤波器对组合图像进行滤波，以强调（增强）组合图像中的对准信息和去强调（潮湿）噪声。一组近似最优的线性滤波器是经修改的二阶差分滤波器，其中内部零点的数量被修改以将滤波器调谐到特定的设备。

4. 发明授权

US07203337B2 Adjusted filters 失效
标题翻译：调整过滤器
公开(公告)号：US07203337B2
公开(公告)日：2007-04-10
申请号：US10174024
申请日：2002-06-18
申请人： Anders Heyden
发明人： Anders Heyden
IPC分类号： G06K9/00 , G06K9/40 , H04N7/18 , H04N9/47
CPC分类号： G08B13/19602 , G06T7/254 , G08B13/19604 , G08B13/1968 , G08B13/19691 , H04N5/147 , H04N7/188
摘要： A method in image processing for detection of a change in the scene in an area. The method comprises the steps of recording a digital image of the area using a sensor and transforming the recorded image by an operator. The operator is based on a previous modeling of changes in the lighting in the area and on a modeling of how the sensor depicts the area in grayscale values in the recorded image. The method further comprises the step of comparing the transformed image with a reference image of the area in order to detect a difference that indicates a change in the scene.
摘要翻译：一种用于检测区域中场景变化的图像处理方法。该方法包括以下步骤：使用传感器记录该区域的数字图像，并由操作者转换记录的图像。操作者基于对该区域中的照明的变化的先前建模以及传感器如何描绘记录图像中的灰度值中的区域的建模。该方法还包括将变换图像与区域的参考图像进行比较以便检测指示场景变化的差异的步骤。

5. 发明授权

US06819353B2 Multiple backgrounds 失效
标题翻译：多个背景
公开(公告)号：US06819353B2
公开(公告)日：2004-11-16
申请号：US09746511
申请日：2000-12-22
申请人： Anders Heyden
发明人： Anders Heyden
IPC分类号： H04N718
CPC分类号： G06K9/00771 , G06T7/254 , G08B13/19602 , G08B13/19604 , G08B13/19667 , H04N7/188
摘要： A method for monitoring a monitored area comprising the steps of recording an image of the monitored area and of comparing the recorded image with a reference image in order to determine whether there is an alarm situation. The method further comprises the step of creating the reference image by combining at least two previously stored images from a set of images, so that the lighting conditions in the reference image are adjusted to the lighting conditions in the recorded image.
摘要翻译：一种用于监视被监视区域的方法，包括以下步骤：记录监视区域的图像，并将记录图像与参考图像进行比较，以便确定是否存在报警情况。该方法还包括通过组合来自一组图像的至少两个先前存储的图像来创建参考图像的步骤，使得参考图像中的照明条件被调整为记录图像中的照明条件。

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