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1. 发明授权

US08545754B2 Radial design oxygenator with heat exchanger 有权
标题翻译：径向设计加氧器与换热器
公开(公告)号：US08545754B2
公开(公告)日：2013-10-01
申请号：US12428674
申请日：2009-04-23
申请人： Walt L. Carpenter , Robert W. Olsen , Michael J. Hobday , Alford L. McLevish , Christopher J. Plott , Roderick E. Briscoe , Patrick J. Cloutier , Anil Thapa , Ming Li , Kevin McIntosh , Ken Merte
发明人： Walt L. Carpenter , Robert W. Olsen , Michael J. Hobday , Alford L. McLevish , Christopher J. Plott , Roderick E. Briscoe , Patrick J. Cloutier , Anil Thapa , Ming Li , Kevin McIntosh , Ken Merte
IPC分类号： A61M1/00 , A61M1/16
CPC分类号： A61M1/1698
摘要： Disclosed is an apparatus for oxygenating and controlling the temperature of blood in an extracorporeal circuit. The apparatus has an inlet and an outlet that is located radially outward from the inlet in order to define a flowpath through the apparatus. The apparatus comprises: a core that is substantially centrally located in the apparatus and to which blood from a patient can be supplied through the inlet; a heat exchanger comprising a plurality of heat transfer elements that are arranged around the core and between which blood from the core can move radially outward; and an oxygenator comprising a plurality of gas exchange elements that are arranged around the heat exchanger and between which blood from the heat exchanger can move radially outward before exiting the apparatus through the outlet.
摘要翻译：公开了一种用于对体外循环中的血液进行氧化和控制的装置。该装置具有从入口径向向外定位的入口和出口，以便限定穿过该装置的流路。所述装置包括：基本中心地位于所述装置中的芯，并且来自患者的血液可以通过所述入口供应到所述芯; 一种热交换器，包括多个传热元件，所述多个传热元件布置在所述芯部周围，并且来自所述芯体的血液可径向向外移动; 以及包括多个气体交换元件的氧合器，所述多个气体交换元件布置在所述热交换器周围，并且在通过所述出口离开所述设备之前，来自所述热交换器的血液可径向向外移动。

2. 发明申请

US20100274170A1 RADIAL DESIGN OXYGENATOR WITH HEAT EXCHANGER 有权
标题翻译：带热交换器的径向设计氧化剂
公开(公告)号：US20100274170A1
公开(公告)日：2010-10-28
申请号：US12428674
申请日：2009-04-23
申请人： Walt L. Carpenter , Robert W. Olsen , Michael J. Hobday , Alford L. McLevish , Christopher J. Plott , Roderick E. Briscoe , Patrick J. Cloutier , Anil Thapa , Ming Li , Kevin McIntosh , Ken Merte
发明人： Walt L. Carpenter , Robert W. Olsen , Michael J. Hobday , Alford L. McLevish , Christopher J. Plott , Roderick E. Briscoe , Patrick J. Cloutier , Anil Thapa , Ming Li , Kevin McIntosh , Ken Merte
IPC分类号： A61M1/36
CPC分类号： A61M1/1698
摘要： Disclosed is an apparatus for oxygenating and controlling the temperature of blood in an extracorporeal circuit. The apparatus has an inlet and an outlet that is located radially outward from the inlet in order to define a flowpath through the apparatus. The apparatus comprises: a core that is substantially centrally located in the apparatus and to which blood from a patient can be supplied through the inlet; a heat exchanger comprising a plurality of heat transfer elements that are arranged around the core and between which blood from the core can move radially outward; and an oxygenator comprising a plurality of gas exchange elements that are arranged around the heat exchanger and between which blood from the heat exchanger can move radially outward before exiting the apparatus through the outlet.
摘要翻译：公开了一种用于对体外循环中的血液进行氧化和控制的装置。该装置具有从入口径向向外定位的入口和出口，以便限定穿过该装置的流路。所述装置包括：基本中心地位于所述装置中的芯，并且来自患者的血液可以通过所述入口供应到所述芯; 一种热交换器，包括多个传热元件，所述多个传热元件布置在所述芯部周围，并且来自所述芯体的血液可径向向外移动; 以及包括多个气体交换元件的氧合器，所述多个气体交换元件布置在所述热交换器周围，并且在通过所述出口离开所述设备之前，来自所述热交换器的血液可径向向外移动。

3. 发明授权

US08439858B2 Arterial blood filter 有权
标题翻译：动脉血液过滤器
公开(公告)号：US08439858B2
公开(公告)日：2013-05-14
申请号：US11948290
申请日：2007-11-30
申请人： Trevor C. Huang , Alford L. McLevish , Joseph L. Kalscheuer , Roderick E. Briscoe
发明人： Trevor C. Huang , Alford L. McLevish , Joseph L. Kalscheuer , Roderick E. Briscoe
IPC分类号： A61M39/00 , A61M37/00 , B01D36/00 , A61M1/34 , A61M1/36
CPC分类号： B01D19/0057 , A61M1/3633 , A61M2206/10 , A61M2206/16
摘要： An arterial line blood filter for use in extracorporeal blood circuits during heart bypass surgery has, among other components, a housing with a cap portion, a base portion, and a generally cylindrical wall portion. The blood filter has a filter element disposed within the housing. An inlet is positioned at an upward angle with respect to the housing and includes an opening in the generally cylindrical wall portion in fluid communication with the inlet chamber. In some embodiments the position of the inlet limits the pressure drop and prime volume of the filter. According to one embodiment, the cap portion has an upwardly sloping inner surface and there is a vent in the cap portion. The inner surface of the cap portion can have a projection proximate the vent configured to limit immobilization of gaseous microemboli within the inlet chamber.
摘要翻译：在心脏旁路手术期间用于体外血液回路的动脉血液过滤器除了其它部件之外还具有具有盖部分，基部部分和大致圆柱形壁部分的壳体。血液过滤器具有设置在壳体内的过滤元件。入口相对于壳体以向上的角度定位，并且在大致圆柱形壁部分中包括与入口室流体连通的开口。在一些实施例中，入口的位置限制了过滤器的压降和原始体积。根据一个实施例，帽部分具有向上倾斜的内表面，并且在帽部分中具有通气口。帽部分的内表面可以具有靠近通气口的突出部，其构造成限制气体微栓塞在入口室内的固定。

4. 发明申请

US20100272606A1 RADIAL FLOW OXYGENATOR/HEAT EXCHANGER 审中-公开
标题翻译：径流式氧化剂/热交换器
公开(公告)号：US20100272606A1
公开(公告)日：2010-10-28
申请号：US12428697
申请日：2009-04-23
申请人： Walt L. Carpenter , Robert W. Olsen , Michael J. Hobday , Alford L. McLevish , Christopher J. Plott , Roderick E. Briscoe , Partick J. Cloutier , Anil Thapa , Ming Li , Kevin McInotosh
发明人： Walt L. Carpenter , Robert W. Olsen , Michael J. Hobday , Alford L. McLevish , Christopher J. Plott , Roderick E. Briscoe , Partick J. Cloutier , Anil Thapa , Ming Li , Kevin McInotosh
IPC分类号： A61M1/36
CPC分类号： A61M1/1698 , A61M1/1006 , A61M1/101 , A61M2206/16
摘要： Described is an apparatus for oxygenating and controlling the temperature of blood in an extracorporeal circuit comprising: an inlet mandrel that is configured such that the blood moves radially outward from the inlet mandrel through the openings in a radial direction; a heat exchanger arranged around the inlet mandrel, wherein blood can move radially outward with the transfer of heat to or from the blood; an oxygenator arranged around the heat exchanger, wherein blood can move from the heat exchanger radially outward with the transfer of oxygen into the blood; and a housing that houses the inlet mandrel, the heat exchanger and the oxygenator, and that comprises a blood inlet in communication with the inlet mandrel in order to allow blood to enter the apparatus from the patient, and a blood outlet in communication with the oxygenator in order for blood to exit the apparatus, wherein the blood outlet is located in the housing radially outward from the inlet.
摘要翻译：描述了一种用于对体外回路中的血液进行氧化和控制的装置，包括：入口心轴，其构造成使得血液从入口心轴径向向外径向通过所述开口径向移动; 布置在入口心轴周围的热交换器，其中血液可以通过向血液或从血液传递热量而径向向外移动; 设置在所述热交换器周围的氧合器，其中，血液可以通过氧气向血液中径向向外从所述热交换器移动; 以及容纳入口心轴，热交换器和氧合器的壳体，并且包括与入口心轴连通的血液入口以允许血液从患者进入设备，以及血液出口与氧合器连通以使血液离开设备，其中血液出口从入口径向向外位于壳体中。

5. 发明申请

US20100272607A1 RADIAL DESIGN OXYGENATOR WITH HEAT EXCHANGER AND INLET MANDREL 审中-公开
标题翻译：带热交换器和入口管的径向设计氧化剂
公开(公告)号：US20100272607A1
公开(公告)日：2010-10-28
申请号：US12428716
申请日：2009-04-23
申请人： Walt L. Carpenter , Robert W. Olsen , Michael J. Hobday , Alford L. McLevish , Christopher J. Plott , Roderick E. Briscoe , Patrick J. Cloutier , Anil Thapa , Ming Li , Kevin McIntosh , Ken Merte
发明人： Walt L. Carpenter , Robert W. Olsen , Michael J. Hobday , Alford L. McLevish , Christopher J. Plott , Roderick E. Briscoe , Patrick J. Cloutier , Anil Thapa , Ming Li , Kevin McIntosh , Ken Merte
IPC分类号： A61M1/36
CPC分类号： A61M1/1698
摘要： Described is an apparatus for oxygenating and controlling the temperature of blood in an extracorporeal circuit, the apparatus having an inlet and an outlet that is located radially outward from the inlet in order to define a flowpath through the apparatus, the apparatus comprising: a core in communication with the inlet such that blood from a patient can be supplied to the core, the core comprising a first element and a second element that interfit to define openings, wherein the elements and the openings together enhance flow of blood from the patient radially outward from the core; a heat exchanger that is arranged about the core and through which blood from the core can move radially outward; and an oxygenator that is arranged about the heat exchanger and through which blood from the heat exchanger can move radially outward before exiting the apparatus through the outlet.
摘要翻译：描述了一种用于对体外循环中的血液进行氧化和控制的装置，该装置具有从入口径向向外定位的入口和出口，以便限定穿过该装置的流路，该装置包括：与入口的连通，使得来自患者的血液可以被供应到芯部，所述芯部包括互相限定开口的第一元件和第二元件，其中所述元件和开口一起增强了来自患者的血液从径向向外的径向向外的流动核心; 布置在芯体周围的热交换器，来自芯体的血液可以通过该热交换器径向向外移动; 以及围绕热交换器布置的氧合器，并且来自热交换器的血液可以在通过出口离开设备之前径向向外移动。

6. 发明申请

US20100269342A1 METHOD OF MAKING RADIAL DESIGN OXYGENATOR WITH HEAT EXCHANGER 审中-公开
标题翻译：具有热交换器的径向设计氧化剂的制备方法
公开(公告)号：US20100269342A1
公开(公告)日：2010-10-28
申请号：US12428706
申请日：2009-04-23
申请人： Walt L. Carpenter , Robert W. Olsen , Michael J. Hobday , Alford L. McLevish , Christopher J. Plott , Roderick E. Briscoe , Patrick J. Cloutier , Anil Thapa , Ming Li
发明人： Walt L. Carpenter , Robert W. Olsen , Michael J. Hobday , Alford L. McLevish , Christopher J. Plott , Roderick E. Briscoe , Patrick J. Cloutier , Anil Thapa , Ming Li
IPC分类号： B21D53/02
CPC分类号： A61M1/1698 , A61M1/1625 , A61M1/1629 , B01D61/00 , B01D63/021 , B01D63/025 , B01D2313/20 , B01D2313/38 , Y10T29/4935
摘要： Described is a method of making an apparatus for oxygenating and controlling the temperature of blood in an extracorporeal circuit, the steps comprising: providing a core through which blood can be supplied to the apparatus from a patient; providing a heat exchanger about the core such that blood from the core can move radially outward through the heat exchanger; providing an oxygenator about the heat exchanger such that blood from the heat exchanger can move radially outward through the oxygenator; and placing the core, heat exchanger and oxygenator in a housing that includes an inlet in communication with the core and an outlet that is located radially outward from the inlet in order to define a flowpath for blood through the apparatus.
摘要翻译：描述了一种制造用于对体外循环中的血液进行氧化和控制的装置的方法，所述步骤包括：提供核心，血液可以通过该核心从患者提供给所述装置; 提供围绕芯的热交换器，使得来自芯的血液可以径向向外移动通过热交换器; 在所述热交换器周围提供氧合器，使得来自所述热交换器的血液可径向向外移动通过所述氧合器; 以及将所述芯，热交换器和氧合器放置在壳体中，所述壳体包括与所述芯部连通的入口和从所述入口径向向外定位的出口，以便限定通过所述设备的血液的流动路径。

7. 发明申请

US20090105630A1 ARTERIAL BLOOD FILTER 有权
标题翻译：动脉血液过滤器
公开(公告)号：US20090105630A1
公开(公告)日：2009-04-23
申请号：US11948290
申请日：2007-11-30
申请人： Trevor C. Huang , Alford L. McLevish , Joseph L. Kalscheuer , Roderick E. Briscoe
发明人： Trevor C. Huang , Alford L. McLevish , Joseph L. Kalscheuer , Roderick E. Briscoe
IPC分类号： A61M1/34
CPC分类号： B01D19/0057 , A61M1/3633 , A61M2206/10 , A61M2206/16
摘要： An arterial line blood filter for use in extracorporeal blood circuits during heart bypass surgery has, among other components, a housing with a cap portion, a base portion, and a generally cylindrical wall portion. The blood filter has a filter element disposed within the housing. An inlet is positioned at an upward angle with respect to the housing and includes an opening in the generally cylindrical wall portion in fluid communication with the inlet chamber. In some embodiments the position of the inlet limits the pressure drop and prime volume of the filter. According to one embodiment, the cap portion has an upwardly sloping inner surface and there is a vent in the cap portion. The inner surface of the cap portion can have a projection proximate the vent configured to limit immobilization of gaseous microemboli within the inlet chamber.
摘要翻译：在心脏旁路手术期间用于体外血液回路的动脉血液过滤器除了其它部件之外还具有具有盖部分，基部部分和大致圆柱形壁部分的壳体。血液过滤器具有设置在壳体内的过滤元件。入口相对于壳体以向上的角度定位，并且在大致圆柱形壁部分中包括与入口室流体连通的开口。在一些实施例中，入口的位置限制了过滤器的压降和原始体积。根据一个实施例，帽部分具有向上倾斜的内表面，并且在帽部分中具有通气口。帽部分的内表面可以具有靠近通气口的突出部，其构造成限制气体微栓塞在入口室内的固定。

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