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1. 发明申请

WO2010062463A1 SHUNT-CURRENT REDUCTION TECHNIQUES FOR AN IMPLANTABLE THERAPY SYSTEM 审中-公开
标题翻译：用于可植入治疗系统的分流电流减少技术
公开(公告)号：WO2010062463A1
公开(公告)日：2010-06-03
申请号：PCT/US2009/058775
申请日：2009-09-29
申请人： MEDTRONIC, INC. , DONOFRIO, William, T. , BURNES, John, E. , KRAUSE, Paul, G. , ARNE, Gerald, P. , ZHOU, Xiaohong
发明人： DONOFRIO, William, T. , BURNES, John, E. , KRAUSE, Paul, G. , ARNE, Gerald, P. , ZHOU, Xiaohong
IPC分类号： A61N1/37 , A61N1/08
CPC分类号： A61N1/3718 , A61N1/08 , A61N1/086 , A61N1/36114 , A61N1/37288
摘要： Techniques for minimizing interference between the first and second medical devices or between the different therapy modules of a common medical device are described herein. In some examples, a medical device may include shunt-current mitigation circuitry and/or at least one clamping structure that helps minimize or even eliminate shunt-current that feeds into a first therapy module of the medical device via one or more electrodes electrically connected to the first therapy module. The shunt-current may be generated by the delivery of electrical stimulation by a second therapy module. The second therapy module may be enclosed in a common housing with the first therapy module or may be separate, e.g., a part of a separate medical device.
摘要翻译：本文描述了用于最小化第一和第二医疗装置之间或在普通医疗装置的不同治疗模块之间的干扰的技术。在一些示例中，医疗装置可以包括分流电流缓解电路和/或至少一个夹持结构，其有助于最小化或甚至消除通过电连接到医疗装置的一个或多个电极馈入医疗装置的第一治疗模块的分流电流第一疗法模块。分流电流可以通过第二治疗模块的电刺激递送来产生。第二治疗模块可以用第一治疗模块封闭在共同的壳体中，或者可以是分离的，例如单独的医疗装置的一部分。

2. 发明申请

WO2010051425A2 IMPLANTABLE MEDICAL DEVICE CROSSTALK EVALUATION AND MITIGATION 审中-公开
公开(公告)号：WO2010051425A2
公开(公告)日：2010-05-06
申请号：PCT/US2009/062719
申请日：2009-10-30
申请人： MEDTRONIC, INC. , KRAUSE, Paul, G. , BURNES, John, E. , DONOFRIO, William, T. , PEICHEL, David, J. , ARNE, Gerald, P. , ZHOU, Xiaohong , REINKE, James, D. , DAVIS, Timothy
发明人： KRAUSE, Paul, G. , BURNES, John, E. , DONOFRIO, William, T. , PEICHEL, David, J. , ARNE, Gerald, P. , ZHOU, Xiaohong , REINKE, James, D. , DAVIS, Timothy
IPC分类号： A61N1/362
CPC分类号： A61N1/3622 , A61N1/36114 , A61N1/36185 , A61N1/3686 , A61N1/3688
摘要： Electrical crosstalk between two implantable medical devices or two different therapy modules of a common implantable medical device may be evaluated, and, in some examples, mitigated. In some examples, one of the implantable medical devices or therapy modules delivers electrical stimulation to a nonmyocardial tissue site or a nonvascular cardiac tissue site, and the other implantable medical device or therapy module delivers cardiac rhythm management therapy to a heart of the patient.

3. 发明申请

WO2010051424A1 IMPLANTABLE MEDICAL DEVICE CROSSTALK EVALUATION AND MITIGATION 审中-公开
公开(公告)号：WO2010051424A1
公开(公告)日：2010-05-06
申请号：PCT/US2009/062718
申请日：2009-10-30
申请人： MEDTRONIC, INC. , BURNES, John, E. , KRAUSE, Paul, G. , DONOFRIO, William, T. , ARNE, Gerald, P. , PEICHEL, David, J. , ZHOU, Xiaohong , REINKE, James, D. , DAVIS, Timothy
发明人： BURNES, John, E. , KRAUSE, Paul, G. , DONOFRIO, William, T. , ARNE, Gerald, P. , PEICHEL, David, J. , ZHOU, Xiaohong , REINKE, James, D. , DAVIS, Timothy
IPC分类号： A61N1/36 , A61B5/053 , A61N1/365 , A61N1/368 , A61N1/372 , A61N1/39
CPC分类号： A61N1/3605 , A61N1/36114 , A61N1/36521 , A61N1/37 , A61N1/37258 , A61N1/37288
摘要： Electrical crosstalk between two implantable medical devices or two different therapy modules of a common implantable medical device may be evaluated, and, in some examples, mitigated. In some examples, one of the implantable medical devices or therapy modules delivers electrical stimulation to a nonmyocardial tissue site or a nonvascular cardiac tissue site, and the other implantable medical device or therapy module delivers cardiac rhythm management therapy to a heart of the patient.

4. 发明申请

WO2010051392A1 THERAPY MODULE CROSSTALK MITIGATION 审中-公开
标题翻译：治疗模块CROSSTALK减缓
公开(公告)号：WO2010051392A1
公开(公告)日：2010-05-06
申请号：PCT/US2009/062650
申请日：2009-10-29
申请人： MEDTRONIC, INC. , DONOFRIO, William, T. , KRAUSE, Paul, G. , ARNE, Gerald, P. , BURNES, John, E. , PEICHEL, David, J. , ZHOU, Xiaohong
发明人： DONOFRIO, William, T. , KRAUSE, Paul, G. , ARNE, Gerald, P. , BURNES, John, E. , PEICHEL, David, J. , ZHOU, Xiaohong
IPC分类号： A61N1/36 , A61N1/372
CPC分类号： A61N1/37288 , A61N1/36114
摘要： A first implantable medical device (IMD) implanted within a patient may communicate with a second IMD implanted within the patient by encoding information in an electrical stimulation signal. The delivery of the electrical stimulation signal may provide therapeutic benefits to the patient. The second IMD may sense the electrical stimulation signal, which may be presented as an artifact in a sensed cardiac signal, and process the sensed signal to retrieve the encoded information. The second IMD may modify its operation based on the received therapy information. Crosstalk between the first and second IMDs may be reduced using various techniques described herein. For example, the first IMD may generate the electrical stimulation signal to include a spread spectrum energy distribution or a predetermined signal signature. The second IMD may effectively remove a least some of the signal artifact in a sensed cardiac signal based on the predetermined signal signature.
摘要翻译：植入在患者体内的第一可植入医疗装置（IMD）可以通过对电刺激信号中的信息进行编码来与植入患者内的第二IMD进行通信。电刺激信号的传递可以为患者提供治疗益处。第二IMD可以感测电刺激信号，其可以被呈现为感测到的心脏信号中的伪像，并且处理感测到的信号以检索经编码的信息。第二IMD可以基于接收到的治疗信息修改其操作。可以使用本文所述的各种技术来减少第一和第二IMD之间的串扰。例如，第一IMD可以产生电刺激信号以包括扩频能量分布或预定信号特征。基于预定的信号签名，第二IMD可以有效地去除感测到的心脏信号中的至少一些信号伪像。

5. 发明申请

WO2010051425A3 IMPLANTABLE MEDICAL DEVICE CROSSTALK EVALUATION AND MITIGATION 审中-公开
标题翻译：可植入医疗设备串扰评估和缓解
公开(公告)号：WO2010051425A3
公开(公告)日：2010-06-24
申请号：PCT/US2009062719
申请日：2009-10-30
申请人： MEDTRONIC INC , KRAUSE PAUL G , BURNES JOHN E , DONOFRIO WILLIAM T , PEICHEL DAVID J , ARNE GERALD P , ZHOU XIAOHONG , REINKE JAMES D , DAVIS TIMOTHY
发明人： KRAUSE PAUL G , BURNES JOHN E , DONOFRIO WILLIAM T , PEICHEL DAVID J , ARNE GERALD P , ZHOU XIAOHONG , REINKE JAMES D , DAVIS TIMOTHY
IPC分类号： A61N1/362 , A61N1/36 , A61N1/368 , A61N1/372
CPC分类号： A61N1/3622 , A61N1/36114 , A61N1/36185 , A61N1/3686 , A61N1/3688
摘要： Electrical crosstalk between two implantable medical devices or two different therapy modules of a common implantable medical device may be evaluated, and, in some examples, mitigated. In some examples, one of the implantable medical devices or therapy modules delivers electrical stimulation to a nonmyocardial tissue site or a nonvascular cardiac tissue site, and the other implantable medical device or therapy module delivers cardiac rhythm management therapy to a heart of the patient.
摘要翻译：可以评估两个可植入医疗装置或常见可植入医疗装置的两个不同治疗模块之间的电串扰，并且在一些示例中可以减轻。在一些示例中，可植入医疗设备或治疗模块中的一个将电刺激递送至非心肌组织部位或非脉管心脏组织部位，并且另一个可植入医疗设备或治疗模块将心律管理治疗递送至患者的心脏。

6. 发明申请

WO2010051482A3 INTERFERENCE MITIGATION FOR IMPLANTABLE DEVICE RECHARGING 审中-公开
公开(公告)号：WO2010051482A3
公开(公告)日：2010-05-06
申请号：PCT/US2009/062833
申请日：2009-10-30
申请人： MEDTRONIC, INC. , KRAUSE, Paul, G. , DONOFRIO, William, T. , ARNE, Gerald, P. , REINKE, James, D. , PEICHEL, David, J. , DAVIS, Timothy , BURNES, John, E.
发明人： KRAUSE, Paul, G. , DONOFRIO, William, T. , ARNE, Gerald, P. , REINKE, James, D. , PEICHEL, David, J. , DAVIS, Timothy , BURNES, John, E.
IPC分类号： A61N1/378 , A61N1/372 , A61N1/37 , H02J7/02
摘要： A therapy or monitoring system may implement one or more techniques to mitigate interference between operation of a charging device that charges a first implantable medical device (IMD) implanted in a patient and a second IMD implanted in the patient. In some examples, the techniques may include modifying an operating parameter of the charging device in response to receiving an indication that a second IMD is implanted in the patient. The techniques also may include modifying an operating parameter of the second IMD in response to detecting the presence or operation of the charging device.

7. 发明申请

WO2010051475A1 IMPLANTABLE MEDICAL DEVICE CROSSTALK EVALUATION AND MITIGATION 审中-公开
公开(公告)号：WO2010051475A1
公开(公告)日：2010-05-06
申请号：PCT/US2009/062822
申请日：2009-10-30
申请人： MEDTRONIC, INC. , DONOFRIO, William, T. , BURNES, John, E. , KRAUSE, Paul, G. , ARNE, Gerald, P. , PEICHEL, David, J. , ZHOU, Xiaohong , REINKE, James, D. , DAVIS, Timothy
发明人： DONOFRIO, William, T. , BURNES, John, E. , KRAUSE, Paul, G. , ARNE, Gerald, P. , PEICHEL, David, J. , ZHOU, Xiaohong , REINKE, James, D. , DAVIS, Timothy
IPC分类号： A61N1/365 , A61B5/053 , A61N1/36 , A61N1/39 , A61N1/372 , A61N1/368
CPC分类号： A61N1/0551 , A61N1/36114 , A61N1/3621 , A61N1/36521 , A61N1/37 , A61N1/37247 , A61N1/37282 , A61N1/3962 , A61N2001/083
摘要： Electrical crosstalk between two implantable medical devices or two different therapy modules of a common implantable medical device may be evaluated, and, in some examples, mitigated. In some examples, one of the implantable medical devices or therapy modules delivers electrical stimulation to a nonmyocardial tissue site or a nonvascular cardiac tissue site, and the other implantable medical device or therapy module delivers cardiac rhythm management therapy to a heart of the patient.

8. 发明申请

WO2010051467A1 IMPLANTABLE MEDICAL DEVICE CROSSTALK EVALUATION AND MITIGATION 审中-公开
公开(公告)号：WO2010051467A1
公开(公告)日：2010-05-06
申请号：PCT/US2009/062808
申请日：2009-10-30
申请人： MEDTRONIC, INC. , BURNES, John, E. , KRAUSE, Paul, G. , DONOFRIO, William, T. , PEICHEL, David, J. , ARNE, Gerald, P. , ZHOU, Xiaohong , REINKE, James, D.
发明人： BURNES, John, E. , KRAUSE, Paul, G. , DONOFRIO, William, T. , PEICHEL, David, J. , ARNE, Gerald, P. , ZHOU, Xiaohong , REINKE, James, D.
IPC分类号： A61N1/365 , A61B5/053 , A61N1/36 , A61N1/39
CPC分类号： A61N1/37 , A61N1/3605 , A61N1/36114 , A61N1/36521 , A61N1/37258 , A61N1/37288
摘要： Electrical crosstalk between two implantable medical devices or two different therapy modules of a common implantable medical device may be evaluated, and, in some examples, mitigated. In some examples, one of the implantable medical devices or therapy modules delivers electrical stimulation to a nonmyocardial tissue site or a nonvascular cardiac tissue site, and the other implantable medical device or therapy module delivers cardiac rhythm management therapy to a heart of the patient.

9. 发明申请

WO2010051426A1 IMPLANTABLE MEDICAL DEVICE CROSSTALK EVALUATION AND MITIGATION 审中-公开
公开(公告)号：WO2010051426A1
公开(公告)日：2010-05-06
申请号：PCT/US2009/062720
申请日：2009-10-30
申请人： MEDTRONIC, INC. , KRAUSE, Paul, G. , BURNES, John, E. , DONOFRIO, William, T. , PEICHEL, David, J. , ARNE, Gerald, P. , ZHOU, Xiaohong , REINKE, James, D.
发明人： KRAUSE, Paul, G. , BURNES, John, E. , DONOFRIO, William, T. , PEICHEL, David, J. , ARNE, Gerald, P. , ZHOU, Xiaohong , REINKE, James, D.
IPC分类号： A61N1/36 , A61N1/372
CPC分类号： A61N1/08 , A61N1/36114 , A61N1/37 , A61N1/37258 , A61N1/37288
摘要： Electrical crosstalk between two implantable medical devices or two different therapy modules of a common implantable medical device may be evaluated, and, in some examples, mitigated. In some examples, one of the implantable medical devices or therapy modules delivers electrical stimulation to a nonmyocardial tissue site or a nonvascular cardiac tissue site, and the other implantable medical device or therapy module delivers cardiac rhythm management therapy to a heart of the patient.

10. 发明申请

WO2010051389A1 COMMUNICATION BETWEEN IMPLANTABLE MEDICAL DEVICES 审中-公开
标题翻译：可植入医疗器械之间的通讯
公开(公告)号：WO2010051389A1
公开(公告)日：2010-05-06
申请号：PCT/US2009/062639
申请日：2009-10-29
申请人： MEDTRONIC, INC. , KRAUSE, Paul, G. , DONOFRIO, William, T. , ARNE, Gerald, P. , BURNS, John, E. , PEICHEL, David, J. , ZHOU, Xiaohong
发明人： KRAUSE, Paul, G. , DONOFRIO, William, T. , ARNE, Gerald, P. , BURNS, John, E. , PEICHEL, David, J. , ZHOU, Xiaohong
IPC分类号： A61N1/372 , A61N1/37 , A61N1/362
CPC分类号： A61N1/37288 , A61N1/36082 , A61N1/362 , A61N1/3706 , A61N1/37217 , A61N1/3727
摘要： A first implantable medical device (IMD) implanted within a patient may communicate with a second IMD implanted within the patient by encoding information in an electrical stimulation signal. The delivery of the electrical stimulation signal may provide therapeutic benefits to the patient. The second IMD may sense the electrical stimulation signal, which may be presented as an artifact in a sensed cardiac signal, and process the sensed signal to retrieve the encoded information. The second IMD may modify its operation based on the received therapy information. Crosstalk between the first and second IMDs may be reduced using various techniques described herein. For example, the first IMD may generate the electrical stimulation signal to include a spread spectrum energy distribution or a predetermined signal signature. The second IMD may effectively remove a least some of the signal artifact in a sensed cardiac signal based on the predetermined signal signature.
摘要翻译：植入在患者体内的第一可植入医疗装置（IMD）可以通过对电刺激信号中的信息进行编码来与植入患者内的第二IMD进行通信。电刺激信号的传递可以为患者提供治疗益处。第二IMD可以感测电刺激信号，其可以被呈现为感测到的心脏信号中的伪像，并且处理感测到的信号以检索经编码的信息。第二IMD可以基于接收到的治疗信息修改其操作。可以使用本文所述的各种技术来减少第一和第二IMD之间的串扰。例如，第一IMD可以产生电刺激信号以包括扩频能量分布或预定信号特征。基于预定的信号签名，第二IMD可以有效地去除感测到的心脏信号中的至少一些信号伪像。

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