专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2004081566A2 METHOD AND DEVICE FOR DETECTING BIOMOLECULES 审中-公开
标题翻译：用于检测生物分子的方法和装置
公开(公告)号：WO2004081566A2
公开(公告)日：2004-09-23
申请号：PCT/EP2004/002685
申请日：2004-03-15
申请人： APIBIO SAS , MANDRAND, Bernard , DUPONT-FILLIARD, Agnès
发明人： MANDRAND, Bernard , DUPONT-FILLIARD, Agnès
IPC分类号： G01N33/53
CPC分类号： B82Y5/00 , C12Q1/6825 , C12Q1/6837 , C12Q2563/125 , C12Q2565/113 , C12Q2565/607 , G01N33/5438 , Y10S977/70 , Y10S977/702 , Y10S977/704 , Y10S977/705 , Y10S977/72
摘要： The present invention relates to a method for detecting a target biomolecule in a sample comprising a plurality of biomolecules, whereby the target biomolecule is provided with a tag, said tag comprising a catalytic active moiety which catalyses a reaction yielding an insoluble reaction product which precipitates on flexible electrically conductive nanoelectrodes. The precipitation onto said nanoelectrodes causes a change in their electroconductivity which is accessible to electroanalytical methods. The invention relates further to a a biochip comprising a solid support with nanoelectrodes attached thereto and probe molecules bound to all or to a plurality of said nanoelectrodes which may be the same or different, a segment of said probe molecules being able to interact specifically with a segment of the target biomolecules.
摘要翻译：本发明涉及用于检测包含多个生物分子的样品中的目标生物分子的方法，由此所述靶生物分子被提供有标签，所述标签包含催化活性部分，其催化产生不溶性反应产物的反应，所述反应产物在柔性导电纳米电极。所述纳米电极上的沉淀导致其电导率的变化，其可用于电分析方法。本发明进一步涉及一种包括固体支持物的生物芯片，其中连接有纳米电极和与所有或多个所述纳米电极结合的探针分子，所述纳米电极可以相同或不同，所述探针分子的片段能够与片段的目标生物分子。

2. 发明申请

WO2005110593A3 PROCESS AND AUTOMATED SYSTEM FOR THE SYNTHESIS OF POLYMERS 审中-公开
标题翻译：用于合成聚合物的工艺和自动化系统
公开(公告)号：WO2005110593A3
公开(公告)日：2006-04-20
申请号：PCT/EP2005005359
申请日：2005-05-17
申请人： APIBIO SAS , LAURENT ALAIN
发明人： LAURENT ALAIN
IPC分类号： B01J19/00 , C40B40/06 , C40B40/10 , C40B40/12 , C40B50/14 , C40B60/14
CPC分类号： B01J19/0046 , B01J2219/00378 , B01J2219/00497 , B01J2219/00527 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/00617 , B01J2219/00637 , B01J2219/00653 , B01J2219/00659 , B01J2219/00675 , B01J2219/00686 , B01J2219/00713 , B01J2219/00722 , B01J2219/00725 , B01J2219/00731 , B82Y30/00 , C40B40/06 , C40B40/10 , C40B40/12 , C40B50/14 , C40B60/14
摘要： The present invention relates to the process for the stepwise synthesis of polymers, especially biopolymers, on a solid support surface comprising the steps of providing a solid support surface having a binding site, applying a first microdroplet of a solution comprising a first polymer building block on said binding site to attach the first polymer building block to the binding site and applying to the modified binding site of the preceding step a second microdroplet of a solution comprising the same or a different polymer building block, wherein the solution comprises two different solvents wich have a different viscosity and its relative viscosity (? rel =? second solvent<
摘要翻译：本发明涉及在固体支持体表面上逐步合成聚合物，特别是生物聚合物的方法，包括以下步骤：提供具有结合位点的固体支持物表面，将包含第一聚合物结构单元的溶液的第一微滴所述结合位点将第一聚合物结构单元连接到结合位点并向前述步骤的修饰结合位点施加包含相同或不同聚合物结构单元的溶液的第二微滴，其中溶液包含两种不同的溶剂，其具有不同的粘度及其相对粘度（η3）

3. 发明申请

WO2004076059A3 SYSTEM AND PROCESS FOR THE SYNTHESIS OF POLYMERS 审中-公开
公开(公告)号：WO2004076059A3
公开(公告)日：2004-09-10
申请号：PCT/EP2004/002040
申请日：2004-03-01
申请人： APIBIO SAS , IMPIKA SA , LAURENT, Alain , SARRA-BOURNET, Philippe , AUDE, Olivier , MORGAVI, Paul , MANDRAND, Bernard , CUZIN, Marc
发明人： LAURENT, Alain , SARRA-BOURNET, Philippe , AUDE, Olivier , MORGAVI, Paul , MANDRAND, Bernard , CUZIN, Marc
IPC分类号： B01J19/00
摘要： The present invention relates to an automated polymer synthesis apparatus for synthesizing a polymer chain onto a solid substrates by sequentially adding polymer building blocks as well as to a method for synthesizing polymers on solid substrates by sequentially reacting polymer building blocks with reactive groups. The invention further relates to a biochip comprising a solid substrate with reactive groups where biomolecules are attached to and the remaining reactive groups are transformed into chemically inert species.

4. 发明申请

WO2005110593A2 PROCESS FOR THE SYNTHESIS OF POLYMERS 审中-公开
标题翻译：合成聚合物的方法
公开(公告)号：WO2005110593A2
公开(公告)日：2005-11-24
申请号：PCT/EP2005/005359
申请日：2005-05-17
申请人： APIBIO SAS , LAURENT, Alain
发明人： LAURENT, Alain
IPC分类号： B01J19/00
CPC分类号： B01J19/0046 , B01J2219/00378 , B01J2219/00497 , B01J2219/00527 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/00617 , B01J2219/00637 , B01J2219/00653 , B01J2219/00659 , B01J2219/00675 , B01J2219/00686 , B01J2219/00713 , B01J2219/00722 , B01J2219/00725 , B01J2219/00731 , B82Y30/00 , C40B40/06 , C40B40/10 , C40B40/12 , C40B50/14 , C40B60/14
摘要： The present invention relates to the process for the stepwise synthesis of polymers, especially biopolymers, on a solid support surface comprising the steps of providing a solid support surface having a binding site, applying a first microdroplet of a solution comprising a first polymer building block on said binding site to attach the first polymer building block to the binding site and applying to the modified binding site of the preceding step a second microdroplet of a solution comprising the same or a different polymer building block, wherein the solution contains a solvent with a viscosity of more than 7 mPa • s. The present invention further relates to a biochip obtainable by a process according to an invention and a further aspect to an automated polymer synthesis system for synthesizing on a solid support a polymer chain by sequentially adding polymer building blocks comprising an inkjet print head, a treatment cell, a transport means and a vessel comprising a solution containing a polymer building block.
摘要翻译：本发明涉及在固体支持体表面上逐步合成聚合物，特别是生物聚合物的方法，包括以下步骤：提供具有结合位点的固体支持物表面，将包含第一聚合物结构单元的溶液的第一微滴所述结合位点将第一聚合物结构单元连接到结合位点，并向前述步骤的改性结合位点施加包含相同或不同聚合物结构单元的溶液的第二微滴，其中溶液含有具有粘度的溶剂超过7 mPa。秒。本发明还涉及可通过根据本发明的方法获得的生物芯片和另一方面的自动化聚合物合成系统，用于通过依次加入包括喷墨印刷头，处理池的聚合物结构单元在固体载体上合成聚合物链，输送装置和包含含有聚合物结构单元的溶液的容器。

5. 发明申请

WO2004076059A2 SYSTEM AND PROCESS FOR THE SYNTHESIS OF POLYMERS 审中-公开
标题翻译：用于合成聚合物的系统和方法
公开(公告)号：WO2004076059A2
公开(公告)日：2004-09-10
申请号：PCT/EP2004002040
申请日：2004-03-01
申请人： APIBIO SAS , IMPIKA SA , LAURENT ALAIN , SARRA-BOURNET PHILIPPE , AUDE OLIVIER , MORGAVI PAUL , MANDRAND BERNARD , CUZIN MARC
发明人： LAURENT ALAIN , SARRA-BOURNET PHILIPPE , AUDE OLIVIER , MORGAVI PAUL , MANDRAND BERNARD , CUZIN MARC
IPC分类号： B01J19/00 , C07K1/04 , C40B40/06 , C40B40/10 , C40B40/12 , C40B50/14 , C40B60/14 , C40B70/00
CPC分类号： B82Y30/00 , B01J19/0046 , B01J2219/0036 , B01J2219/00378 , B01J2219/00423 , B01J2219/00497 , B01J2219/00529 , B01J2219/00572 , B01J2219/00585 , B01J2219/0059 , B01J2219/00596 , B01J2219/00608 , B01J2219/0061 , B01J2219/00617 , B01J2219/00626 , B01J2219/00659 , B01J2219/00662 , B01J2219/00675 , B01J2219/00689 , B01J2219/00693 , B01J2219/00722 , B01J2219/00725 , B01J2219/00731 , C07K1/04 , C07K1/045 , C40B40/06 , C40B40/10 , C40B40/12 , C40B50/14 , C40B60/14 , C40B70/00
摘要： The present invention relates to an automated polymer synthesis apparatus for synthesizing a polymer chain onto a solid substrates by sequentially adding polymer building blocks as well as to a method for synthesizing polymers on solid substrates by sequentially reacting polymer building blocks with reactive groups. The invention further relates to a biochip comprising a solid substrate with reactive groups where biomolecules are attached to and the remaining reactive groups are transformed into chemically inert species.
摘要翻译：本发明涉及通过依次添加聚合物结构单元而将聚合物链合成到固体基材上的自动化聚合物合成装置以及通过使聚合物结构单元与反应性基团顺序反应而在固体基材上合成聚合物的方法。本发明进一步涉及一种生物芯片，其包含具有反应性基团的固体基质，其中生物分子连接到其上并且其余的反应性基团转化成化学惰性物质。

6. 发明申请

WO2004037405A1 BIOCHIP AND METHOD FOR PROCESSING A PLURALITY OF FIOCHIPS 审中-公开
标题翻译：用于处理多种发泡剂的生物技术和方法
公开(公告)号：WO2004037405A1
公开(公告)日：2004-05-06
申请号：PCT/EP2003/011900
申请日：2003-10-27
申请人： APIBIO SAS , CUZIN, Marc
发明人： CUZIN, Marc
IPC分类号： B01J19/00
CPC分类号： B01J19/0046 , B01J2219/00497 , B01J2219/00529 , B01J2219/00565 , B01J2219/00569 , B01J2219/00576 , B01J2219/00578 , B01J2219/00587 , B01J2219/00596 , B01J2219/00653 , B01J2219/00659 , B01J2219/00662 , B01J2219/00689 , B01J2219/00691 , B01J2219/00722 , B01J2219/00725 , C40B40/06 , C40B40/10
摘要： The present invention provides a biochip (100) comprising a continuous solid support (101) whereby an array area (102) comprising a plurality of electrodes (103) for the fixation of modules is arranged on said solid support (101), said biochip (100) further comprising a labeling area (104) which is spaced apart from said array area, said labeling area (104) is in connection with transmitter means (105) capable of receiving and transmitting RF signals, said labeling area (104) further comprising remotely RF addressable memory means for storing a plurality of data relating to the identity of or to information related with the biochip (100). The invention further provides a system for the processing of a plurality of biochip arrays and a method for the processing of such biochip arrays.
摘要翻译：本发明提供了一种包括连续固体支持物（101）的生物芯片（100），由此在所述固体支持物（101）上布置包括用于固定模块的多个电极（103）的阵列区域（102），所述生物芯片 100）还包括与所述阵列区域间隔开的标记区域（104），所述标记区域（104）与能够接收和发射RF信号的发射机装置（105）相连，所述标记区域（104）还包括远程RF可寻址存储器装置，用于存储与生物芯片（100）相关的信息或与其相关的信息。本发明还提供了一种用于处理多个生物芯片阵列的系统和用于处理这种生物芯片阵列的方法。

7. 发明申请

WO2004081566A3 METHOD AND DEVICE FOR DETECTING BIOMOLECULES 审中-公开
标题翻译：检测生物分子的方法和装置
公开(公告)号：WO2004081566A3
公开(公告)日：2004-12-02
申请号：PCT/EP2004002685
申请日：2004-03-15
申请人： APIBIO SAS , MANDRAND BERNARD , DUPONT-FILLIARD AGNES
发明人： MANDRAND BERNARD , DUPONT-FILLIARD AGNES
IPC分类号： C12Q1/68 , G01N33/543
CPC分类号： B82Y5/00 , C12Q1/6825 , C12Q1/6837 , C12Q2563/125 , C12Q2565/113 , C12Q2565/607 , G01N33/5438 , Y10S977/70 , Y10S977/702 , Y10S977/704 , Y10S977/705 , Y10S977/72
摘要： The present invention relates to a method for detecting a target biomolecule in a sample comprising a plurality of biomolecules, whereby the target biomolecule is provided with a tag, said tag comprising a catalytic active moiety which catalyses a reaction yielding an insoluble reaction product which precipitates on flexible electrically conductive nanoelectrodes. The precipitation onto said nanoelectrodes causes a change in their electroconductivity which is accessible to electroanalytical methods. The invention relates further to a a biochip comprising a solid support with nanoelectrodes attached thereto and probe molecules bound to all or to a plurality of said nanoelectrodes which may be the same or different, a segment of said probe molecules being able to interact specifically with a segment of the target biomolecules.
摘要翻译：本发明涉及一种用于检测包含多种生物分子的样品中的靶生物分子的方法，其中所述靶生物分子具有标签，所述标签包含催化活性部分，所述催化活性部分催化反应，产生沉淀的不溶性反应产物柔性导电纳米电极。在所述纳米电极上的沉淀导致其电导率的改变，这可以通过电分析方法获得。本发明进一步涉及一种生物芯片，其包括具有附着于其上的纳米电极的固体支持物和与全部或多个所述纳米电极结合的探针分子，所述纳米电极可以相同或不同，所述探针分子的片段能够特异性地与片段的目标生物分子。

8. 发明申请

WO2004037422A1 DEVICE FOR DISPENSING CHEMICAL SPECIES ON SURFACES 审中-公开
标题翻译：用于在表面上分配化学物质的装置
公开(公告)号：WO2004037422A1
公开(公告)日：2004-05-06
申请号：PCT/EP2003/011955
申请日：2003-10-28
申请人： APIBIO SAS , MANDRAND, Bernard , GUY, Michel
发明人： MANDRAND, Bernard , GUY, Michel
IPC分类号： B01L3/02
CPC分类号： B01L3/0262 , B01L2200/143 , B01L2200/146 , B01L2400/025 , B01L2400/027 , B01L2400/0415 , G01N2035/1037
摘要： The present invention relates to a device for dispensing chemical species onto substrates for use in generating a biological and/or biochemical assay plate for detecting the presence of mobile target reactants that bind to probe reactants immobilized on said assay plate, said device comprising a chamber for holding said liquid species, a channel having a first end communicating with said chamber and a second end through which said chemical species is delivered when said device is brought into contact with said substrates and a wire being located in the channel. The object to provide a device for dispensing chemical species onto substrates that is easier to handle and has a more reliable operation than devices according to the state of the art is solved according to the present invention by a device where said wire is connected with a drop weight.
摘要翻译：本发明涉及一种用于将化学物质分配到基底上以用于产生生物和/或生物化学测定板的装置，用于检测结合固定在所述测定板上的探针反应物的流动目标反应物的存在，所述装置包括用于保持所述液体物质，具有与所述室连通的第一端的通道和当所述装置与所述基板接触并且位于所述通道中的导线时所述化学物质被输送的第二端。根据本发明，通过一种装置解决了提供用于将化学物质分配到基板上更容易处理并且具有比根据现有技术的装置更可靠的操作的装置的目的，其中所述导线与一滴重量。

9. 发明专利

DE10308931A1 未知
公开(公告)号：DE10308931A1
公开(公告)日：2004-09-23
申请号：DE10308931
申请日：2003-02-28
申请人： APIBIO SAS GRENOBLE , IMPIKA SA AUBAGNE
发明人： LAURENT ALAIN , SARRA-BOURNET PHILIPPE , AUDE OLIVIER , MORGAVI PAUL , BERNARD MANDRAND , CUZIN MARC
IPC分类号： B01J19/00 , C07K1/04 , C40B40/06 , C40B40/10 , C40B40/12 , C40B50/14 , C40B60/14 , C40B70/00 , C07H21/00 , C07H1/00
摘要： The present invention relates to an automated polymer synthesis apparatus for synthesizing a polymer chain onto a solid substrates by sequentially adding polymer building blocks as well as to a method for synthesizing polymers on solid substrates by sequentially reacting polymer building blocks with reactive groups. The invention further relates to a biochip comprising a solid substrate with reactive groups where biomolecules are attached to and the remaining reactive groups are transformed into chemically inert species.

10. 发明专利

AU2003285301A1 BIOCHIP AND METHOD FOR PROCESSING A PLURALITY OF FIOCHIPS 未知
公开(公告)号：AU2003285301A1
公开(公告)日：2004-05-13
申请号：AU2003285301
申请日：2003-10-27
申请人： APIBIO SAS
发明人： CUZIN MARC
IPC分类号： B01J19/00 , C40B40/06 , C40B40/10

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式