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1. 发明申请

WO2010124110A1 DUAL-PHASE CALCIUM PHOSPHATE CEMENT COMPOSITION 审中-公开
标题翻译：双相磷酸钙水泥组合物
公开(公告)号：WO2010124110A1
公开(公告)日：2010-10-28
申请号：PCT/US2010/032084
申请日：2010-04-22
申请人： AMERICAN DENTAL ASSOCIATION FOUNDATION , CHOW, Laurence C. , SHOZO, Takagi
发明人： CHOW, Laurence C. , SHOZO, Takagi
IPC分类号： A61K33/42 , C01B25/37
CPC分类号： C04B28/34 , A61L24/001 , A61L24/0063 , A61L24/043 , C04B40/065 , C04B2111/00836 , C04B22/16 , C04B24/06 , C04B2103/12 , C04B2103/44 , C04B24/383 , C04B38/10
摘要： Disclosed are dual-phase cement precursor systems and associated methods and kits. The cement precursor systems comprises at least first and second phases each containing a calcium phosphate compound. When mixed, the first and second cement precursor phases form a biocompatible cement. The disclosed systems include an organic acid in an amount effective to enhance the working time of the cement precursor composition, and also include a setting accelerator. In some embodiments, one or more of the calcium phosphate compounds is provided in the form of particles with a nonmonomial particle sized distribution.
摘要翻译：公开了双相水泥前体体系及相关方法和试剂盒。水泥前体体系至少包含含有磷酸钙化合物的第一相和第二相。当混合时，第一和第二水泥前体相形成生物相容的水泥。所公开的系统包括有效提高水泥前体组合物的工作时间的有机酸，还包括凝固促进剂。在一些实施方案中，一种或多种磷酸钙化合物以非单调粒度分布的颗粒形式提供。

2. 发明申请

WO2006057857A2 COMPOSITIONS AND METHODS FOR WHITENING, MINERALIZING AND/OR FLUORIDATING CALCIFIED TISSUES 审中-公开
标题翻译：白化，矿化和/或氟化计算的组织的组合物和方法
公开(公告)号：WO2006057857A2
公开(公告)日：2006-06-01
申请号：PCT/US2005/041319
申请日：2005-11-15
申请人： AMERICAN DENTAL ASSOCIATION FOUNDATION , TUNG, Ming, S.
发明人： TUNG, Ming, S.
IPC分类号： A61K8/22
CPC分类号： A61K8/19 , A61K8/20 , A61K8/22 , A61K8/23 , A61K8/24 , A61K8/36 , A61K8/365 , A61K8/42 , A61K2800/31 , A61K2800/88 , A61Q11/00
摘要： Kits and methods that combine whitening/stain removal of teeth with remineralization are disclosed. These kits advantageously comprise separate compositions comprising a soluble calcium salt, a soluble orthophosphate salt, and a soluble peroxide, in order to optimize the stability of these components for storage and/or the activity of these components upon use. The active ingredients may also be separated in a solid composition (e.g., a powder) or in a stable dispersion comprising a non-aqueous dispersion medium.
摘要翻译：公开了将美白/去除牙齿与再矿化的组合和方法。这些试剂盒有利地包含分离的组合物，其包含可溶性钙盐，可溶性正磷酸盐和可溶性过氧化物，以便在使用时优化这些组分用于储存和/或这些组分的活性的稳定性。活性成分也可以在固体组合物（例如粉末）中或在包含非水分散介质的稳定分散体中分离。

3. 发明申请

WO2012119155A1 ANTIMICROBIAL COMPOSITIONS FOR TOOTH FLUORIDATION AND REMINERALIZATION 审中-公开
标题翻译：用于牙齿氟化和清除的抗微生物组合物
公开(公告)号：WO2012119155A1
公开(公告)日：2012-09-07
申请号：PCT/US2012/027765
申请日：2012-03-05
申请人： AMERICAN DENTAL ASSOCIATION FOUNDATION , TUNG, Ming S.
发明人： TUNG, Ming S.
IPC分类号： A61Q11/00
CPC分类号： A61Q11/00 , A01N47/44 , A61K6/0017 , A61K6/0035 , A61K6/0067 , A61K8/411 , A61Q17/005 , A01N59/26 , A01N2300/00
摘要： Compositions and methods for delivering, in an oral environment, chlorhexidine in combination with beneficial ions selected from calcium, phosphate, fluoride, silver, and carbonate ions are described. These compositions and methods may involve the formation of chlorhexidine compounds either prior to use or in situ. Representative compounds include chlorhexidine fluoride (ChxF), chlorhexidine phosphate (ChxP), chlorhexidine calcium fluoride (ChxCF), chlorhexidine phosphate fluoride (ChxPF), chlorhexidine calcium phosphate (ChxCP), chlorhexidine calcium phosphate fluoride (ChxCPF), chlorhexidine silver calcium phosphate fluoride (ChxACPF) or the compositions or methods which will form these noble chlorhexidine compounds when applied to the tooth. Two or more of these chlorhexidine compounds may be formed as an aggregate, or one or more of these chlorhexidine compounds may be formed as an aggregate with calcium fluoride (CaF2).
摘要翻译：描述了在口服环境中将氯己定与选自钙，磷酸盐，氟化物，银和碳酸根离子的有益离子组合的组合物和方法。这些组合物和方法可以涉及在使用前或原位形成氯己定化合物。代表性的化合物包括氯己定氟化物（ChxF），氯己定磷酸盐（ChxP），氯己定氟化钙（ChxCF），氯己定氟化磷（ChxPF），氯己定磷酸钙（ChxCP），氯己定磷酸氟化钙（ChxCPF），氯己定银磷酸钙氟 ChxACPF）或当应用于牙齿时形成这些贵重氯己定化合物的组合物或方法。这些氯己定化合物中的两种或更多种可以形成为骨料，或者这些氯己啶化合物中的一种或多种可以与氟化钙（CaF 2）形成为骨料。

4. 发明申请

WO2010039878A1 APPARATUS AND METHODS FOR TESTING THE POLISHABILITY OF MATERIALS 审中-公开
标题翻译：用于测试材料的可抛光性的装置和方法
公开(公告)号：WO2010039878A1
公开(公告)日：2010-04-08
申请号：PCT/US2009/059094
申请日：2009-09-30
申请人： AMERICAN DENTAL ASSOCIATION FOUNDATION , NJEGOVAN, Nikola , MEGREMIS, Spiro , SIROVSKAYA, Olga , SHEPELAK, Hank
发明人： NJEGOVAN, Nikola , MEGREMIS, Spiro , SIROVSKAYA, Olga , SHEPELAK, Hank
IPC分类号： A61C17/16
CPC分类号： G01B21/30 , G01B5/28
摘要： A method and apparatus for measuring the polishability of a solid material such as a dental restorative material includes using a series of apparatus to perform the steps of forming the material into a desired specimen with a generally planar surface, conditioning the surface by abrasion, measuring the abraded surface with a profile determination device, optionally measuring the amount of material abraded from the surface and the gloss of the abraded surface, polishing a portion of the abraded surface with a polishing device at a controlled load for a pre-determined time and measuring the roughness and/or gloss of the polished surface followed by comparison thereof to the corresponding measurements of the unpolished, conditioned portion of the specimen surface. Polishing materials and devices may also be tested using the apparatus and method for polishing a standardized material.
摘要翻译：用于测量诸如牙科修复材料的固体材料的可抛光性的方法和设备包括使用一系列装置来执行将材料形成为具有大致平坦表面的所需样品的步骤，通过磨损调节表面，测量研磨表面用轮廓确定装置，可选地测量从表面磨蚀的材料的量和磨损表面的光泽，用研磨装置在受控负载下抛光磨损表面的一部分预定时间并测量抛光表面的粗糙度和/或光泽度，然后将其与样品表面的未抛光调理部分的相应测量值进行比较。也可以使用用于抛光标准化材料的装置和方法来测试抛光材料和装置。

5. 发明申请

US20040154407A1 Polymer shrinkage tensometer 失效
标题翻译：聚合物收缩张力计
公开(公告)号：US20040154407A1
公开(公告)日：2004-08-12
申请号：US10640774
申请日：2003-08-14
申请人： AMERICAN DENTAL ASSOCIATION FOUNDATION
发明人： Frederick C. Eichmiller
IPC分类号： G01N003/22
CPC分类号： G01N3/08 , G01N2203/0016 , G01N2203/0033 , G01N2203/0092
摘要： An apparatus and method for measuring the characteristics of curing polymers. The apparatus and method utilize cantilever beam technology to determine characteristics of polymers during the curing process, including but not limited to, stress-related forces that develop during the polymer curing process. The apparatus and method also provide for controlling and monitoring environmental conditions during the curing process.
摘要翻译：用于测量固化聚合物特性的装置和方法。该设备和方法利用悬臂梁技术来确定聚合物在固化过程中的特性，包括但不限于在聚合物固化过程中产生的应力相关力。该设备和方法还提供了在固化过程中控制和监测环境条件。

6. 发明公开

EP2421543A1 DUAL-PHASE CALCIUM PHOSPHATE CEMENT COMPOSITION 有权
标题翻译： ZWEIPHASEN-CALCIUMPHOSPHATZEMENTZUSAMMENSETZUNG
公开(公告)号：EP2421543A1
公开(公告)日：2012-02-29
申请号：EP10767776.7
申请日：2010-04-22
申请人： American Dental Association Foundation
发明人： CHOW, Laurence C. , SHOZO, Takagi
IPC分类号： A61K33/42 , C01B25/37
CPC分类号： C04B28/34 , A61L24/001 , A61L24/0063 , A61L24/043 , C04B40/065 , C04B2111/00836 , C04B22/16 , C04B24/06 , C04B2103/12 , C04B2103/44 , C04B24/383 , C04B38/10
摘要： Disclosed are dual-phase cement precursor systems and associated methods and kits. The cement precursor systems comprises at least first and second phases each containing a calcium phosphate compound. When mixed, the first and second cement precursor phases form a biocompatible cement. The disclosed systems include an organic acid in an amount effective to enhance the working time of the cement precursor composition, and also include a setting accelerator. In some embodiments, one or more of the calcium phosphate compounds is provided in the form of particles with a nonmonomial particle sized distribution.

7. 发明公开

EP2334254A1 APPARATUS AND METHODS FOR TESTING THE POLISHABILITY OF MATERIALS 失效转让
标题翻译：设备和测试抛光材料的方法，
公开(公告)号：EP2334254A1
公开(公告)日：2011-06-22
申请号：EP09818464.1
申请日：2009-09-30
申请人： American Dental Association Foundation
发明人： NJEGOVAN, Nikola , MEGREMIS, Spiro , SIROVSKAYA, Olga , SHEPELAK, Hank
IPC分类号： A61C17/16
CPC分类号： G01B21/30 , G01B5/28
摘要： A method and apparatus for measuring the polishability of a solid material such as a dental restorative material includes using a series of apparatus to perform the steps of forming the material into a desired specimen with a generally planar surface, conditioning the surface by abrasion, measuring the abraded surface with a profile determination device, optionally measuring the amount of material abraded from the surface and the gloss of the abraded surface, polishing a portion of the abraded surface with a polishing device at a controlled load for a pre-determined time and measuring the roughness and/or gloss of the polished surface followed by comparison thereof to the corresponding measurements of the unpolished, conditioned portion of the specimen surface. Polishing materials and devices may also be tested using the apparatus and method for polishing a standardized material.

8. 发明授权

EP2421543B1 DUAL-PHASE CALCIUM PHOSPHATE CEMENT COMPOSITION 有权
公开(公告)号：EP2421543B1
公开(公告)日：2019-06-12
申请号：EP10767776.7
申请日：2010-04-22
申请人： American Dental Association Foundation
发明人： CHOW, Laurence C. , SHOZO, Takagi
IPC分类号： A61K33/42 , C01B25/37

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