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1. 发明申请

WO2009099291A3 POTASSIUM ORGANOTRIFLUOROBORATE DERIVATIVE AND A PRODUCTION METHOD THEREFOR 审中-公开
标题翻译：有机三氟硼酸钾衍生物及其生产方法
公开(公告)号：WO2009099291A3
公开(公告)日：2009-10-01
申请号：PCT/KR2009000532
申请日：2009-02-04
申请人： SNU R&DB FOUNDATION , KANG HEONJOONG , HAM JUNGYEOB , AHN HONG RYUL , PARK YOUNG HEE
发明人： KANG HEONJOONG , HAM JUNGYEOB , AHN HONG RYUL , PARK YOUNG HEE
IPC分类号： C07F5/02
CPC分类号： C07F5/02
摘要： The present invention relates to a production method for a potassium organotrifluoroborate compound having a hydroxyl group, and to a novel potassium organotrifluoroborate compound having a hydroxyl group. The production method according to the present invention is advantageous in that a potassium organotrifluoroborate compound can be produced in a single reaction without recourse to a process of isolating and purifying an intermediate. The novel potassium organotrifluoroborate compound having a hydroxyl group according to the present invention is useful as a reactant which is widely used in the total synthesis of physiologically active natural products and diverse organic synthesis reactions including halogen substitution reactions, 1,2- and 1,4- addition reactions using a rhodium (Rh) catalyst, and Suzuki carbon-carbon coupling reactions (Suzuki coupling reactions) using a palladium (Pd) catalyst.
摘要翻译：本发明涉及具有羟基的有机三氟硼酸钾化合物的制造方法，以及具有羟基的新型有机三氟硼酸钾化合物。根据本发明的制造方法的优点在于，有机三氟硼酸钾化合物可以在单一反应中生产而无需依靠分离和纯化中间体的方法。根据本发明的具有羟基的新型有机钾三氟硼酸钾化合物可用作广泛用于生理活性天然产物的全合成和各种有机合成反应的反应物，包括卤素取代反应，1,2-和1,4 - 使用铑（Rh）催化剂的加成反应，和使用钯（Pd）催化剂的Suzuki碳 - 碳偶联反应（Suzuki偶联反应）。

2. 发明申请

WO2009014315A1 A COMPOSITION THAT IS COMPRISING EXTRACTS, FRACTIONS OR ISOLATED SINGLE COMPOUNDS OF ROBINIA PSEUDO-ACACIA VAR. UMBRACULIFERA 审中-公开
标题翻译：包含罗毕尼亚PSEUDO-ACACIA VAR的提取物，分离物或分离的单一化合物的组合物。 UMBRACULIFERA
公开(公告)号：WO2009014315A1
公开(公告)日：2009-01-29
申请号：PCT/KR2008/003283
申请日：2008-06-12
申请人： KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY , KIM, Su Nam , LEE, Woo Jung , KWON, Hak Cheol , HAM, Jungyeob , AHN, Hong Ryul , KIM, Myung Soo , NAM, Chun-Woo , LEE, Jong-Nam , LIM, Ju-Sung , PARK, Hyun Bong , PARK, Yeon-Suk
发明人： KIM, Su Nam , LEE, Woo Jung , KWON, Hak Cheol , HAM, Jungyeob , AHN, Hong Ryul , KIM, Myung Soo , NAM, Chun-Woo , LEE, Jong-Nam , LIM, Ju-Sung , PARK, Hyun Bong , PARK, Yeon-Suk
IPC分类号： A61K36/48 , C07C43/00
CPC分类号： A61K36/48 , C07C39/21 , C07D311/32
摘要： The present invention relates to a composition containing the extract of Robinia pseudo-acacia var. umbraculifera(Robinia pseudo-acacia var. umbraculifera) , fractions thereof and compounds isolated therefrom as an active ingredient, more precisely a composition containing the extract of Robinia pseudo-acacia var. umbraculifera extracted with water, alcohol or a mixture thereof as a solvent, fractions thereof and compounds isolated therefrom such as amorphastilbol or 5, 7-dihydroxy-6-geranyl flavanone, or its pharmaceutically acceptable salts which can activate peroxisome proliferator-activated receptor (PPAR) to bring the effect of prevention or treatment of obesity, diabetes, inflammation, skin aging, wrinkles. So, the extract of Robinia pseudo-acacia var. umbraculifera , fractions thereof and compounds isolated therefrom of the present invention can be effectively used as an active ingredient for medicines, food and drink or compositions for skin external application.
摘要翻译：本发明涉及含有刺槐提取物的组合物。芜菁（Robinia pseudo-acacia var。umbraculifera），其分数和作为活性成分分离的化合物，更确切地说是含有刺槐提取物的组合物。以水，醇或其作为溶剂的混合物，其馏分和从其分离的化合物如阿莫法星或5,7-二羟基-6-香叶基黄烷酮或其可以活化过氧化物酶体增殖物激活受体（PPAR）的药学上可接受的盐提取）带来预防或治疗肥胖，糖尿病，炎症，皮肤老化，皱纹的效果。所以，刺槐拟提取物本发明的级分和与其分离的化合物可以有效地用作药物，食品和饮料或外用皮肤组合物的活性成分。

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