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1. 发明申请

US20230115750A1 METHODS AND COMPOSITIONS FOR IDENTIFIYING A SURVIVABILITY INDEX FOR AN ANIMAL 有权
公开(公告)号：US20230115750A1
公开(公告)日：2023-04-13
申请号：US17904742
申请日：2021-02-25
申请人： Advanced Animal Diagnostics, Inc.
发明人： Rodolfo R. Rodriguez , Brian Pike , Ada Tsoi , Stefano Bresolin , Jasper N. Pollard , Joy Parr Drach , Mitchell Hockett , Norah Gerow Bate , Danielle Stewart Noel , Felipe Guirado Dantas
IPC分类号： G01N33/50
摘要： The present invention provides a method of identifying and mitigating a risk of deathloss of an animal, comprising receiving, at a processor from a hematology analyzer, information obtained from a sample from said animal, wherein said information comprises a leukocyte absolute count and a leukocyte differential from said sample, said sample comprising leukocytes, analyzing, by said processor, said leukocyte absolute count and said leukocyte differential to determine a survivability index for said animal, and managing the animal based on the survivability index.

2. 发明授权

US10827963B2 Apparatus for rapid collection of blood from livestock 有权
公开(公告)号：US10827963B2
公开(公告)日：2020-11-10
申请号：US15882621
申请日：2018-01-29
申请人： Advanced Animal Diagnostics, Inc.
发明人： John Richard Sink , Jasper N. Pollard , Gustavo Pena , Deborah Asion , Mitchell Hockett , Joy Parr Drach , Martha Payne , David A. Calderwood
IPC分类号： A61B5/00 , A61B5/15 , A61B5/153 , A61M5/34 , B01L3/02 , A61M5/31 , A61M5/315
摘要： An apparatus useful for the rapid collection of blood from a subject (e.g., a blood vessel, such as the vein, artery or capillary bed of a bovine subject) and dispensing the blood therefrom into a test or collection device. In general, the apparatus comprises: (a) a body having a chamber formed therein, said chamber having an inlet and outlet, with said chamber configured to draw blood therein; (b) a hollow barrel connected to said chamber outlet; (c) an ejector operatively associated with said barrel; (d) a hollow needle connected to said body, with said hollow needle in fluid communication with said chamber through said inlet, so that blood can be rapidly drawn into said chamber through said needle. The needle is optionally removed and blood dispensed from the body into a test or collection device by actuating the ejector.

3. 发明授权

US10222383B2 Methods and compositions for detecting mycoplasma exposure 有权
公开(公告)号：US10222383B2
公开(公告)日：2019-03-05
申请号：US15418477
申请日：2017-01-27
申请人： Advanced Animal Diagnostics, Inc.
发明人： Robert L. Campbell , Melissa E. Langer , Jasper N. Pollard , Robert L. Cheek , Kevin G. Dolan , W. William Stewart , Stefano Bresolin , John Richard Sink , Tobias M. Heineck , Laura A. Black , Nathan F. Pope , Lauren K. Parker , Erik J. Jensen , Jorge Carlos Correa , Reha O. Azizoglu
IPC分类号： G01N33/68 , G01N33/558 , G01N33/569
摘要： The present invention provides methods and compositions for detecting Mycoplasma exposure in a subject.

4. 发明申请

US20180228417A1 Apparatus for Rapid Collection of Blood from Livestock 审中-公开
公开(公告)号：US20180228417A1
公开(公告)日：2018-08-16
申请号：US15882621
申请日：2018-01-29
申请人： Advanced Animal Diagnostics, Inc.
发明人： John Richard Sink , Jasper N. Pollard , Gustavo Pena , Deborah Asion , Mitchell Hockett , Joy Parr Drach , Martha Payne , David A. Calderwood
IPC分类号： A61B5/15 , A61B5/153
CPC分类号： A61B5/150061 , A61B5/150022 , A61B5/15003 , A61B5/150099 , A61B5/150213 , A61B5/150221 , A61B5/150236 , A61B5/150259 , A61B5/150389 , A61B5/150503 , A61B5/150755 , A61B5/1535 , A61B2503/40 , A61M5/31531 , A61M5/343 , A61M5/344 , A61M5/346 , A61M2005/3128 , B01L3/0217
摘要： An apparatus useful for the rapid collection of blood from a subject (e.g., a blood vessel, such as the vein, artery or capillary bed of a bovine subject) and dispensing the blood therefrom into a test or collection device. In general, the apparatus comprises: (a) a body having a chamber formed therein, said chamber having an inlet and outlet, with said chamber configured to draw blood therein; (b) a hollow barrel connected to said chamber outlet; (c) an ejector operatively associated with said barrel; (d) a hollow needle connected to said body, with said hollow needle in fluid communication with said chamber through said inlet, so that blood can be rapidly drawn into said chamber through said needle. The needle is optionally removed and blood dispensed from the body into a test or collection device by actuating the ejector.

5. 发明授权

US09816982B2 Diagnostic apparatus 有权
公开(公告)号：US09816982B2
公开(公告)日：2017-11-14
申请号：US13928741
申请日：2013-06-27
申请人： Advanced Animal Diagnostics, Inc.
发明人： Stefano Bresolin , David A. Calderwood , Tobias M. Heineck , David Newcomb , Chris Paul , Jasper N. Pollard , Rodolfo R. Rodriguez , Demetris Young
IPC分类号： H04N7/18 , G01N33/50 , G06T7/00 , G02B21/00 , G06F1/20 , G02B21/26
CPC分类号： G01N33/5094 , G01N2800/365 , G02B21/00 , G02B21/0016 , G02B21/26 , G06F1/20 , G06T7/0012
摘要： An automated microscope apparatus, comprises an outer housing having an external wall; optionally but preferably an internal wall in said housing, and configured to form a first compartment and a separate second compartment in said outer housing; a microscope assembly in said housing, preferably in said first compartment; and a microprocessor in said housing, preferably in said second compartment; and optionally but preferably a heat sink mounted on said housing external wall, preferably adjacent said second compartment, with said microprocessor thermally coupled to said heat sink and operatively associated with said microscope assembly.

6. 发明申请

US20150233919A1 RAPID DETECTION OF ANALYTES IN LIQUID SAMPLES 有权
标题翻译：快速检测液体样品中的分析物
公开(公告)号：US20150233919A1
公开(公告)日：2015-08-20
申请号：US14700753
申请日：2015-04-30
申请人： Advanced Animal Diagnostics, Inc.
发明人： Rodolfo R. Rodriguez , David A. Calderwood
IPC分类号： G01N33/569
CPC分类号： G01N33/56933 , A61K39/02 , G01N33/558
摘要： A device for detecting at least one analyte (and in some embodiments two, three, or four or more different analytes) in a liquid sample generally comprises (i) a support having a chamber for receiving a biological fluid therein, wherein said chamber is an elongate chamber having a length axis; (ii) a carrier or agitator in said elongate chamber, said carrier or agitator having opposite end portions and a side portion, the carrier or agitator dimensioned to travel in said chamber along said length axis and/or permit said liquid sample to flow in the chamber therearound, either (or both) thereby agitating the liquid sample; and (iii) at least one anti-analyte antibody coupled to either the carrier and/or the chamber side wall.
摘要翻译：用于检测液体样品中至少一种分析物（并且在一些实施方案中为两种，三种，或四种或更多种不同分析物）的装置通常包括（i）具有用于在其中接收生物流体的室的载体，其中所述室是细长室具有长度轴; （ii）所述细长室中的载体或搅拌器，所述载体或搅拌器具有相对的端部部分和侧部分，所述载体或搅拌器的尺寸被设计成沿着所述长度轴线在所述室中运行和/或允许所述液体样品在（或两者），从而搅动液体样品; 和（iii）至少一种与载体和/或室侧壁偶联的抗分析物抗体。

7. 发明申请

US20140233098A1 DIAGNOSTIC APPARATUS 审中-公开
标题翻译：诊断装置
公开(公告)号：US20140233098A1
公开(公告)日：2014-08-21
申请号：US14239208
申请日：2013-07-02
申请人： ADVANCED ANIMAL DIAGNOSTICS, INC.
发明人： Stefano Bresolin , David A. Calderwood , Tobias M. Heineck , David Newcomb , Chris Paul , Jasper N. Pollard , Rodolfo R. Rodriguez , Demetris Young
IPC分类号： G02B21/26 , G02B21/28 , G01N33/487
CPC分类号： G02B21/26 , G01N33/48785 , G02B21/0016 , G02B21/28 , G06F1/20
摘要： An automated microscope apparatus comprises an outer housing having an external wall; optionally but preferably an internal wall in the housing configured to form a first compartment and a separate second compartment in the outer housing; a microscope assembly in the housing (preferably in the first compartment); a microprocessor in the housing (preferably in the second compartment), and (optionally but preferably) a heat sink mounted on the housing external wall, preferably adjacent the second compartment, with the microprocessor thermally coupled to said heat sink and operatively associated with the microscope assembly. Systems and methods employing the same are also described, along with component parts thereof.
摘要翻译：自动显微镜装置包括具有外壁的外壳; 可选地，优选地，壳体中的内壁被构造成在外壳中形成第一隔室和单独的第二隔室; 壳体（优选地在第一隔室）中的显微镜组件; 壳体（优选地在第二隔间）中的微处理器，以及（可选地，但优选地）安装在壳体外壁上，优选地邻近第二隔室的散热器，微处理器热耦合到所述散热器并且与显微镜可操作地相关联部件。还描述了使用其的系统和方法及其组成部分。

8. 发明申请

US20210270803A1 METHODS AND COMPOSITIONS FOR REDUCING ANTIBIOTIC ADMINISTRATION TO FARM ANIMALS 有权
公开(公告)号：US20210270803A1
公开(公告)日：2021-09-02
申请号：US17175114
申请日：2021-02-12
申请人： Advanced Animal Diagnostics, Inc.
发明人： Joy Parr Drach , Mitchell Hockett , Stefano Bresolin , Erik J. Jensen , Tobias M. Heineck , Jasper N. Pollard , Deborah Asion , Rodolfo R. Rodriguez , David A. Calderwood , Norah Gerow Bate , John Richard Sink , Jorge Carlos Correa
IPC分类号： G01N33/49
摘要： The present invention provides a method of identifying an animal for which antibiotic treatment, anti-infective treatment, probiotic treatment, immunostimulant treatment, additional monitoring and/or a separate or alternative management strategy is appropriate, comprising: a) collecting a sample from said animal; b) performing a leukocyte differential cell count on said sample; c) comparing said leukocyte differential cell count of (b) with an index of infection; and d) initiating antibiotic treatment, anti-infective treatment, probiotic treatment, immunostimulant treatment, additional monitoring and/or a separate or alternative management strategy of said animal on the basis of said comparing step.

9. 发明授权

US10426445B2 Sample collection and transfer assembly and related methods 有权
公开(公告)号：US10426445B2
公开(公告)日：2019-10-01
申请号：US14394900
申请日：2013-06-20
申请人： Advanced Animal Diagnostics, Inc.
发明人： David A. Calderwood , Joy Parr Drach , Chris Paul , Rodolfo R. Rodriguez , Mitch Hockett , Randall Marcuson , Stephen G. Miggels , Demetris Young
IPC分类号： A61B10/00 , A01J5/04 , B01L3/00 , G01N1/10 , A61B90/96 , A61B90/90 , A61B90/94 , A61B90/98 , G01N1/28 , G01N33/04
摘要： A collection device includes a base housing member having at least one chamber. A cover housing member has at least one aperture therein, and the cover housing member is configured to cover the base housing member such that the at least one aperture is positioned in fluid communication with the at least one chamber. The cover housing member includes a cartridge holding interface configured to releasably engage with a cartridge that is configured to cover and receive a fluid from the at least one chamber via the at least one aperture.

10. 发明申请

US20180172676A1 Diagnostic Apparatus 审中-公开
公开(公告)号：US20180172676A1
公开(公告)日：2018-06-21
申请号：US15810534
申请日：2017-11-13
申请人： Advanced Animal Diagnostics, Inc.
发明人： Stefano Bresolin , David A. Calderwood , Tobias M. Heineck , David Newcomb , Chris Paul , Jaspar N. Pollard , Rodolfo R. Rodriguez , Demetris Young
IPC分类号： G01N33/50 , G02B21/00 , G06T7/00 , G02B21/26 , G06F1/20
CPC分类号： G01N33/5094 , G01N2800/365 , G02B21/00 , G02B21/0016 , G02B21/26 , G06F1/20 , G06T7/0012
摘要： An automated microscope apparatus, comprises an outer housing having an external wall; optionally but preferably an internal wall in said housing, and configured to form a first compartment and a separate second compartment in said outer housing; a microscope assembly in said housing, preferably in said first compartment; and a microprocessor in said housing, preferably in said second compartment; and optionally but preferably a heat sink mounted on said housing external wall, preferably adjacent said second compartment, with said microprocessor thermally coupled to said heat sink and operatively associated with said microscope assembly.

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