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    • 2. 发明专利
    • Thin film polymer structure, and method for preparing the same
    • 薄膜聚合物结构及其制备方法
    • JP2012187926A
    • 2012-10-04
    • JP2012074496
    • 2012-03-28
    • Shinji Takeoka真司 武岡
    • TAKEOKA SHINJIOKAMURA YOSUKEFUJIEDA TOSHINOBUUTSUNOMIYA SAORIGOTO TAKAHIRO
    • B32B9/00A61K9/70A61L15/00C08J5/18C08J5/20
    • B32B37/02A61K9/0014A61K9/70A61K9/7007B32B38/10C08J5/18C08J7/12C12N5/0068C12N2535/10Y10T156/10Y10T428/31504
    • PROBLEM TO BE SOLVED: To provide a functional thin film polymer structure useful for a functional carrier and a blood platelet alternative in a drug delivery system, and a skin external application medicine such as a wound coating agent, a conglutination inhibitor, a skin-care cosmetic and the like.SOLUTION: The thin film polymer structure has a functional substance on each of the surface A and surface B. The method of preparing the thin film polymer structure includes the steps of: (a) causing polyfunctional molecules to be adsorbed to an area of an arbitrary shape in an interface between a substrate body and a liquid phase; (b) polymerizing and/or crosslinking the adsorbing polyfunctional molecules to form a polymer thin film; (c) bonding a functional substance to the surface A of the formed thin film and then (d) forming a soluble support film thereon; exfoliating the thin film and the soluble support film from the substrate body; (e) bonding to the surface B of the thin film a functional substance identical to or different from the above functional substance and then dissolving the soluble support film with a solvent.
    • 要解决的问题:提供可用于药物递送系统中的功能性载体和血小板替代物的功能性薄膜聚合物结构,以及皮肤外用药如伤口包衣剂,粘连抑制剂, 护肤化妆品等。 解决方案:薄膜聚合物结构在表面A和表面B的每一个上具有功能性物质。制备薄膜聚合物结构的方法包括以下步骤:(a)使多官能分子吸附到区域 在基体和液相之间的界面中具有任意形状; (b)使吸附的多官能分子聚合和/或交联以形成聚合物薄膜; (c)将功能性物质结合到所形成的薄膜的表面A上,然后(d)在其上形成可溶性载体膜; 将薄膜和可溶性支撑膜从基体体层剥离; (e)将与所述功能物质相同或不同的功能性物质与所述薄膜的表面B接合,然后用溶剂溶解所述可溶性载体膜。 版权所有(C)2013,JPO&INPIT