专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明专利

JP4323148B2 n- alkanoyl hyaluronic acid or a salt thereof and its manufacturing method 有权
公开(公告)号：JP4323148B2
公开(公告)日：2009-09-02
申请号：JP2002285769
申请日：2002-09-30
申请人：チッソ株式会社 , 伸彦由井
发明人：剛名嘉真 , 亨大谷 , 伸彦由井
IPC分类号： A61K9/02 , C08B37/08 , A61K47/36 , A61L15/44 , A61L31/00
摘要： PROBLEM TO BE SOLVED: To provide a new type hyaluronic acid (or its salt) having hydrophobic sites and hydrophilic sites and useful as a novel material in the fields of medicine, food, and cosmetics and a method for producing the same. SOLUTION: The n-alkanoylated hyaluronic acid or its salt is represented by formula (I) and prepared by reacting a complex of hyaluronic acid or its salt and a cationic compound with an n-alkanoyl halide in a nonaqueous solvent. In formula (I), R 1 to R 4 are each H or a 4-18C n-alkanoyl group; R 5 is H, a metal cation, or a cationic compound; and n is an integer of 2-7,500. COPYRIGHT: (C)2004,JPO

2. 发明专利

JPWO2003074099A1 組織再生用基材、移植用材料及びその製法有权
公开(公告)号：JPWO2003074099A1
公开(公告)日：2005-06-23
申请号：JP2003572612
申请日：2003-03-05
申请人：由井伸彦 , 伸彦由井 , 株式会社ジャパン・ティッシュ・エンジニアリング , 株式会社ジャパン・ティッシュ・エンジニアリング
发明人：由井　伸彦 , 伸彦由井 , 加藤　雅一 , 雅一加藤 , 里佳福島 , 里佳福島
IPC分类号： A61L27/00 , A61L27/18 , A61L27/38 , A61L27/52 , C12N5/077 , C12N5/10
CPC分类号： A61L27/52 , A61L27/18 , A61L27/38 , C12N5/0655 , C08L101/02
摘要：本発明の組織再生用基材は、複数の環状分子を貫通させた線状分子の両末端に加水分解性結合を介して嵩高い置換基を有する生体親和性基が導入されたポリロタキサン、又は、このポリロタキサンにつき隣合うポリロタキサン1分子中に含まれる環状分子同士、生体親和性基同士もしくは環状分子と生体親和性基とを架橋結合で架橋して網目構造としたポリロタキサンヒドロゲルからなる組織再生用基材において、前記環状分子が細胞接着性を付与するアミノ基のような修飾基を有するものである(例えばアミノ化ヒドロゲル)。この組織再生用基材を用いて例えば軟骨細胞を培養すると、細胞は軟骨細胞様の形態を維持しながら増殖する。特に、アミノ基のような修飾基がない場合に比べて細胞を効率よく保持することができる。

3. 发明专利

JP3480672B2 Biocompatible polyolefin moldings, and biocompatible polymer materials 失效
公开(公告)号：JP3480672B2
公开(公告)日：2003-12-22
申请号：JP12957998
申请日：1998-04-23
申请人：チッソ株式会社 , 稔寺野 , 伸彦由井
发明人：稔寺野 , 尚史川本 , 伸彦由井 , 安弘白石
IPC分类号： A61L31/00 , A61L33/00
摘要： PROBLEM TO BE SOLVED: To obtain a polyolefin molding and a crystalline polymer material excellent in compatibility in which the adsorption of blood plasma protein is restrained. SOLUTION: The biocompatibility is imparted to a polyolefin molding by controlling the molding conditions thereof in such a way that the bonding work to the molding surface of polyolefin is 15 J/m or less, and the adsorptive energy of water to the surface thereof is 7.7 kJ/mol or more. The material surface in which the adsorption of blood plasma protein is restrained can be obtained by imparting orientation to the crystalline polymer material such as polyolefin. The imparting of orientation is enabled by restraining the conditions, for instance, such as the extension, injection molding, and hollow molding. The degree of orientation of 10% or more is preferable.

4. 发明专利

JP2003327545A Carrier for captured substance, complex of carrier and captured substance, method of introducing captured substance and adsorbent 审中-公开
标题翻译：承运物质载体，载体和捕获物质的复合物，引入捕获物质和吸附物的方法
公开(公告)号：JP2003327545A
公开(公告)日：2003-11-19
申请号：JP2002134351
申请日：2002-05-09
申请人： Atsushi Maruyama , Nobuhiko Yui , 厚丸山 , 伸彦由井
发明人： MARUYAMA ATSUSHI , YUI NOBUHIKO , OTANI TORU
IPC分类号： C12N15/09 , A61K31/7088 , A61K47/30 , A61K47/34 , A61K47/40 , A61K47/48 , A61K48/00 , B01J20/26
摘要： PROBLEM TO BE SOLVED: To provide a carrier for captured substance having a high safety, capable of producing in an industrial scale, effectively passing the captured substance through a membrane in a simple operation, and to provide a complex of the carrier and the captured substance obtained by linking the captured substance to the carrier for captured substance, a method of introduction for the captured substance using the carrier for the captured substance, and an adsorbent having adsorbing function to component of the membrane.
SOLUTION: The carrier forms the complex with the captured substance to assist the captured substance to pass through the membrane, comprises more than one cyclic molecule having functional groups as substituents bonding with the captured substance, a linear molecule holding the more than one cyclic molecules in a penetrating state and bulky substituents capping both ends of the linear molecules.
COPYRIGHT: (C)2004,JPO
摘要翻译：要解决的问题：为了提供能够以工业规模生产的具有高安全性的捕获物质的载体，能够以简单的操作有效地将捕获的物质通过膜，并提供载体和通过将捕获物质与被捕获物质的载体连接而得到的捕获物质，使用捕捉物质的载体的被捕获物质的引入方法以及对膜的成分具有吸附功能的吸附剂。解决方案：载体与捕获的物质形成复合物，以帮助捕获的物质通过膜，包含多于一个具有作为与捕获物质结合的取代基的官能团的环状分子，保持多于一个的直链分子处于穿透状态的环状分子和封闭线性分子两端的大体积取代基。版权所有（C）2004，JPO

5. 发明专利

JP4753525B2 Tissue regeneration for the base material, for transplant material and its manufacturing method 有权
公开(公告)号：JP4753525B2
公开(公告)日：2011-08-24
申请号：JP2002506780
申请日：2000-11-27
申请人：株式会社ジャパン・ティッシュ・エンジニアリング , 伸彦由井
发明人：雅一加藤 , 亨大谷 , 剛之山本 , 伸彦由井
IPC分类号： A61L27/00 , A61L27/14 , A61L27/18 , A61L27/38 , A61L27/52 , C12N5/00 , C12N5/077
CPC分类号： C12N5/0068 , A61L27/14 , A61L27/18 , A61L27/38 , A61L27/52 , C08L101/00 , C12N5/0655 , C12N2533/30 , C12N2533/70
摘要： Base materials for tissue regeneration which enable the tissue regeneration, have mechanical properties needed in the tissue regeneration and can disappear via degradation in vivo after the completion of the tissue regeneration; and implantable materials with the use of the same. The above-described base materials for tissue regeneration comprise polyrotaxane, wherein biocompatible groups having bulky substituents have been introduced via hydrolyzable bond into both ends of a linear molecule penetrating plural cyclic molecules, or a polyrotaxane hydrogel having a network structure formed by crosslinking the cyclic molecules to each other, the biocompatible groups to each other, or the cyclic molecules to the biocompatible groups in each polyrotaxane molecule.

6. 发明专利

JP3704194B2 Percutaneous absorption-promoting substances and their preparation 失效
公开(公告)号：JP3704194B2
公开(公告)日：2005-10-05
申请号：JP7649196
申请日：1996-03-29
申请人：伸彦由井
发明人：伸彦由井
IPC分类号： A61K9/00 , A61K47/40 , C08B37/16 , C08G65/08 , C08G65/28

7. 发明专利

JP3699141B2 Biodegradable pharmaceutical macromolecular assemblies of supramolecular structures and methods for their preparation 失效
公开(公告)号：JP3699141B2
公开(公告)日：2005-09-28
申请号：JP25487294
申请日：1994-09-24
申请人：伸彦由井
发明人：伸彦由井
IPC分类号： A61K31/724 , A61K38/00 , A61K47/48
CPC分类号： B82Y5/00 , A61K47/6951

8. 发明专利

JP2004323453A Decomposable gel and method for producing the same 审中-公开
公开(公告)号：JP2004323453A
公开(公告)日：2004-11-18
申请号：JP2003122860
申请日：2003-04-25
申请人： Chisso Corp , Nobuhiko Yui , チッソ株式会社 , 伸彦由井
发明人： YUI NOBUHIKO , OTANI TORU , NAKAMA TAKESHI , SATO IKUO , KAWABATA RYOJI
IPC分类号： A61K9/06 , A61K8/02 , A61K8/72 , A61K31/728 , A61K47/36 , C09K3/00 , A61K7/00
CPC分类号： A61K47/36 , A61K31/728
摘要： PROBLEM TO BE SOLVED: To provide a decomposable gel readily not decomposed and having sufficient strength and a method for producing the same.
SOLUTION: The decomposable gel has ≤98 wt.% saturated water content. The decomposable gel is preferably a polysaccharide gel. The polysaccharide gel is preferably an anionic polysaccharide gel.
COPYRIGHT: (C)2005,JPO&NCIPI

9. 发明专利

JP4104556B2 Tissue regeneration for the base material, for transplant material and its manufacturing method 有权
公开(公告)号：JP4104556B2
公开(公告)日：2008-06-18
申请号：JP2003572612
申请日：2003-03-05
申请人：株式会社ジャパン・ティッシュ・エンジニアリング , 伸彦由井
发明人：雅一加藤 , 伸彦由井 , 里佳福島
IPC分类号： A61L27/00 , A61L27/18 , A61L27/38 , A61L27/52 , C12N5/077
CPC分类号： A61L27/52 , A61L27/18 , A61L27/38 , C12N5/0655 , C08L101/02

10. 发明专利

JP2005053974A Polysaccharide cross-linked product and method for producing the same 有权
标题翻译：多糖交联产物及其生产方法
公开(公告)号：JP2005053974A
公开(公告)日：2005-03-03
申请号：JP2003206329
申请日：2003-08-06
申请人： Chisso Corp , Nobuhiko Yui , チッソ株式会社 , 伸彦由井
发明人： YUI NOBUHIKO , OTANI TORU , NAKAMA TAKESHI , KAWABATA RYOJI
IPC分类号： C08B37/08
摘要： PROBLEM TO BE SOLVED: To provide a polysaccharide cross-linked product which is little swollen after cross-linked, and can easily be produced in the same size and shape as those of a mold used for the production and even in a complicated shape, to provide a method for producing the same, to provide a polysaccharide cross-linked product whose degradation reaction can be adjusted with an enzyme and is useful for the sustained release of a functional substance such as a medicine and as a substrate material for regenerative medicines, and to provide a method for producing the same.
SOLUTION: This method for producing the polysaccharide cross-linked product comprises lyophilizing an aqueous solution of a carboxy group-having polysaccharide and then cross-linking the lyophilized product with a condensing agent. The polysaccharide cross-linked product obtained by the production method.
COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：提供交联后少量溶胀的多糖交联产物，并且可以容易地与用于生产的模具相同的尺寸和形状生产，甚至在复杂的形成，以提供其制备方法，以提供其降解反应可以用酶调节的多糖交联产物，并且可用于药物等功能性物质的持续释放和用于再生的基质材料药物，并提供其制备方法。解决方案：该多糖交联产物的制备方法包括冻干含羧基多糖的水溶液，然后用冷凝剂交联冻干产物。通过生产方法得到的多糖交联产物。版权所有（C）2005，JPO＆NCIPI

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式