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1. 发明申请

WO2023078929A1 IMPROVED CONVERSION OF SOLAR HEAT TO ELECTRICITY 审中-公开
公开(公告)号：WO2023078929A1
公开(公告)日：2023-05-11
申请号：PCT/EP2022/080551
申请日：2022-11-02
申请人： AELLA SA
发明人： TEPIC, Slobodan
IPC分类号： F24S10/50 , F24S60/10 , F24S60/30 , F24S90/00
摘要： A solar heat powerplant comprising: a first heat reservoir which is a cold reservoir (3), a second heat reservoir which is a hot reservoir (1), at least one heat exchanger (5) adapted for radiative dry cooling of the cold reservoir (3) and/or for radiative heating of the hot reservoir (1) by absorbing solar irradiation, and a power generator (8) which operates by extracting heat from the hot reservoir (1) and transferring residual heat into the cold reservoir (3).

2. 发明申请

WO2023057228A1 MULTI-STAGED AXIAL COMPRESSOR PROPULSION MOTOR FOR AN ELECTRIC PROPULSION AIRCRAFT 审中-公开
公开(公告)号：WO2023057228A1
公开(公告)日：2023-04-13
申请号：PCT/EP2022/076422
申请日：2022-09-22
申请人： LILIUM EAIRCRAFT GMBH
发明人： WEBER, Florian
IPC分类号： F04D19/02 , F04D25/06 , H02K16/02 , H02K21/12 , H02K1/32 , H02K9/06 , B60L2200/10 , B60L2220/50 , B64C11/001 , B64D27/24 , F04D19/022 , F04D19/024 , F04D25/0606
摘要： The present invention relates to a multi-staged axial compressor propulsion motor (10) for an electrical propulsion aircraft, comprising a housing (16), defining a substantially cylindrical inner space (16a) and a longitudinal axis (L); at least two compressor stages (12, 14) arranged in the inner space (16a) of the housing (16) in a rotatable manner one behind the other along the longitudinal axis (L), wherein each compressor stage (12, 14) comprises an inner blade ring (12b, 14b) and an outer blade ring (12c, 14c) with a plurality of blades (12a, 14a) extending between the inner (12b, 14b) and outer (12c, 14c) blade rings; and an electrical drive assembly (24) adapted to drive at least two of the compressor stages (12, 14) in a counter-rotating manner.

3. 发明申请

WO2023041758A1 ARGINASE-INSULIN FUSION PROTEIN 审中-公开
公开(公告)号：WO2023041758A1
公开(公告)日：2023-03-23
申请号：PCT/EP2022/075887
申请日：2022-09-19
申请人： KYON BIOTECH AG
发明人： TEPIC, Slobodan
IPC分类号： C07K14/62
摘要： The invention discloses a fusion protein of insulin and arginase useful as an anti-tumor medication, an anti-obesity medication or a type-2 diabetes medication.

4. 发明申请

WO2022263405A1 GELLAN GUM COMPOSITIONS AND METHOD FOR THEIR PREPARATION 审中-公开
公开(公告)号：WO2022263405A1
公开(公告)日：2022-12-22
申请号：PCT/EP2022/066099
申请日：2022-06-14
申请人： AUREGEN BIOTHERAPEUTICS SA
发明人： KESTI, Matti Jaakko Johannes , YEWEY, Gary
IPC分类号： C08B37/00 , C08L5/00 , A61K47/36
摘要： The present invention generally relates to the field of biopolymers. In one aspect, the invention is directed to a method of preparing lyophilized and reconstituted gellan gum compositions. In further aspects, the invention relates to lyophilized compositions comprising gellan gum, reconstituted gellan gum compositions, dosage-unit formulations comprising lyophilized gellan gum, and their use in medicine or other sterile applications.

5. 发明申请

WO2022248454A1 NOVEL CRISPR GRNAS 审中-公开
公开(公告)号：WO2022248454A1
公开(公告)日：2022-12-01
申请号：PCT/EP2022/064019
申请日：2022-05-24
申请人： MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V.
发明人： RIESENBERG, Stephan , MARICIC, Tomislav , HEMBRECHT, Nelly
IPC分类号： C12N15/11 , C12N15/113
摘要： The present invention relates to a guide RNA (gRNA) suitable for CRISPR-mediated oligonucleotide binding and/or editing comprising at least one hairpin that does not interact with a Cas enzyme wherein said hairpin forms a locked secondary structure.

6. 发明申请

WO2022207822A1 ANTI-NECTIN-4-ANTIBODIES AND USES THEREOF 审中-公开
公开(公告)号：WO2022207822A1
公开(公告)日：2022-10-06
申请号：PCT/EP2022/058626
申请日：2022-03-31
申请人： EMERGENCE THERAPEUTICS AG , UNIVERSITE D’AIX-MARSEILLE , INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) , INSTITUT JEAN PAOLI & IRENE CALMETTES , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE – CNRS –
发明人： ELANDS, Jack , LHOSPPICE, Florence , PRÉVILLE, Xavier , OLIVE, Daniel , LOPEZ, Marc
IPC分类号： A61P35/00 , A61K38/17 , A61K47/68 , C07K16/28 , A61K38/00 , A61K41/00 , A61K47/50 , A61K49/00 , A61K47/6803 , A61K47/6849 , A61K47/6851 , C07K16/2803 , C07K2317/92
摘要： The present invention relates to antibodies having specificity to Nectin-4 and uses thereof.

7. 发明申请

WO2022184765A1 NOVEL CRISPR-Cas NUCLEASES FROM METAGENOMES 审中-公开
公开(公告)号：WO2022184765A1
公开(公告)日：2022-09-09
申请号：PCT/EP2022/055257
申请日：2022-03-02
申请人： BRAIN BIOTECH AG
发明人： SCHOLZ, Paul , ZUREK, Christian , BACK, Robin
IPC分类号： C12N15/10 , C12N9/16
摘要： The present invention relates to a nucleic acid molecule encoding an RNA-guided DNA endonuclease, which is (a) a nucleic acid molecule encoding the RNA-guided DNA endonuclease comprising or consisting of the amino acid sequence of any one of SEQ ID NOs 9, 1 to 5, 7, 8 and 10 to 15; (b) a nucleic acid molecule comprising or consisting of the nucleotide sequence of any one of SEQ ID NOs 24, 16 to 20, 22, 23 and 25 to 30; (c) a nucleic acid molecule encoding a RNA-guided DNA endonuclease the amino acid sequence of which is at least 70% identical to the amino acid sequence of (a), preferably at least 80 % identical, more preferably at least 90% identical, and most preferred at least 95% identical; (d) a nucleic acid molecule comprising or consisting of a nucleotide sequence which is at least 70% identical to the nucleotide sequence of (b), preferably at least 80 % identical, more preferably at least 90% identical, and most preferred at least 95% identical; (e) a nucleic acid molecule which is degenerate with respect to the nucleic acid molecule of (d); or (f) a nucleic acid molecule corresponding to the nucleic acid molecule of any one of (a) to (d) wherein T is replaced by U.

8. 发明申请

WO2022180142A1 EFFEKTPERMANENTES HYDROPHOBIERUNGSMITTEL 审中-公开
公开(公告)号：WO2022180142A1
公开(公告)日：2022-09-01
申请号：PCT/EP2022/054604
申请日：2022-02-24
申请人： RUDOLF GMBH
发明人： ALBERT, Christine , SCHUBERT, Maximilian , HORNUNG, Pauline , SIELEMANN, Dirk
IPC分类号： C08G77/388 , C09D183/10 , D06M15/643 , D06M15/564 , D06M15/568 , C09D183/08
摘要： Die Erfindung betrifft Organopolysiloxane enthaltend mindestens eine Struktureinheit mit mindestens einer C8-28-Alkylgruppe und mindestens einer Harnstoffgruppe, ein Verfahren zu deren Herstellung, eine Zubereitung umfassend das Organopolysiloxan, sowie die Verwendung als Hydrophobierungsmittel.

9. 发明申请

WO2022175117A1 BATTERY MODULE 审中-公开
公开(公告)号：WO2022175117A1
公开(公告)日：2022-08-25
申请号：PCT/EP2022/052740
申请日：2022-02-04
申请人： LILIUM EAIRCRAFT GMBH
发明人： PITRE, Ryan , PLAZA, Angel , WEBER, Joerg , FRITSCH, Gerd , DUNTHORN, Jason , SCHEILE, Felix , ADER, Armin , KNEISSL, Stefan , PULIPAKA, Pradeep , LEAL, Marina
IPC分类号： H01M50/211 , H01M50/229 , H01M50/231 , H01M50/233 , H01M50/30
摘要： A battery module (10) for a vehicle, in particular for an aircraft, comprises two end plates (12) and a cell stack (14) comprising an arrangement of several interconnected battery cells (16), in particular pouch cells, that are arranged in a row along a stacking direction (S), wherein the cell stack (14) is sandwiched between the two end plates (12) in the stacking direction (S), wherein the battery module (10) further comprises a separate tube-like enclosure (18) comprising a heat insulating material, the tube-like enclosure having a front opening (18f) and a back opening (18b) that are closed by the end plates (12), so that the tube-like enclosure (18) and the two end plates (12) form a housing (20) in which the cell stack (14) is accommodated.

10. 发明申请

WO2022175113A1 BATTERY MODULE WITH THERMAL MANAGEMENT SYSTEM 审中-公开
公开(公告)号：WO2022175113A1
公开(公告)日：2022-08-25
申请号：PCT/EP2022/052725
申请日：2022-02-04
申请人： LILIUM EAIRCRAFT GMBH
发明人： PITRE, Ryan , PLAZA, Angel , WEBER, Joerg , FRITSCH, Gerd , SCHEILE, Felix , ADER, Armin , DIETRICH, Axel
IPC分类号： H01M10/625 , H01M10/6556 , H01M10/6567 , H01M50/211 , H01M50/342
摘要： A battery module (10) for a vehicle (100), in particular for an aircraft, comprises a housing (20), a cell stack (14) accommodated in the housing (20), an internal channel system (26) for heat transfer fluid disposed in the housing (20), a fluid inlet connector (42) and a fluid outlet connector (44) connected to the internal channel system (26) and adapted to being connected to an external thermal management system, wherein the fluid inlet connector (42) and the fluid outlet connector (44) are self-sealing connectors molded into the housing (20), preferably self-sealing and dripless connectors.

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