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1. 发明申请

WO2017204349A1 METHODS AND ASSAYS FOR ESTIMATING ACID-FAST BACTERIA VIABILITY, AND KITS THEREFOR 审中-公开
标题翻译：估算酸 - 细菌生存能力的方法和试剂及其试剂盒
公开(公告)号：WO2017204349A1
公开(公告)日：2017-11-30
申请号：PCT/JP2017/019794
申请日：2017-05-26
申请人： OTSUKA PHARMACEUTICAL CO., LTD.
发明人： KAWASAKI, Masanori , LIU, Yongge , KATSURAGI, Kiyonori
IPC分类号： C12Q1/24 , C07K16/12 , G01N33/569
摘要： The present invention relates to assays and methods for calculating, estimating, or determining, the amount of viable acid-fast bacilli in a sample based on the result of the detection of lipoarabinomannan (LAM). The present disclosure further relates to the detection of LAM of acid-fast bacilli using an antibody, and calculating, estimating, or determining, the amount of viable acid-fast bacilli in a sample based on the result of the detection of LAM. These assays and methods may be used for the monitoring of treatments for tuberculosis, and for the development and testing of new treatments.
摘要翻译：本发明涉及用于基于脂阿拉伯甘露聚糖（LAM）的检测结果来计算，估计或确定样品中存活的抗酸杆菌的量的测定法和方法。本发明还涉及使用抗体检测抗酸杆菌的LAM，并基于LAM的检测结果计算，估计或确定样品中存活的抗酸杆菌的量。这些测定和方法可用于监测结核病治疗，以及开发和测试新的治疗方法。

2. 发明申请

WO2017188260A1 COMPOSITIONS OF PHARMACEUTICAL PRODUCT WITH INGESTIBLE EVENT MARKER 审中-公开
标题翻译：具有增值事件标记的药物产品组合物
公开(公告)号：WO2017188260A1
公开(公告)日：2017-11-02
申请号：PCT/JP2017/016395
申请日：2017-04-25
申请人： OTSUKA PHARMACEUTICAL CO., LTD.
发明人： ZDEBLICK, Mark , CHRISTEN, Markus , PARGAONKAR, Nikhil , LEIST, Nikolaus , SCHEINPFLUG, Kurt , JOHNSON, Patricia , COSTELLO, Benedict
IPC分类号： A61K31/496 , A61J3/06 , A61J7/00 , A61K9/20 , A61K47/02 , A61K47/46 , A61P25/18
摘要： In some embodiments, a composition of matter includes aripiprazole, a metal selected from the group consisting of magnesium, zinc, sodium, lithium, iron, or alloys thereof, or combinations thereof and a copper salt selected from the group consisting of copper iodide, copper chloride, copper bromide, copper sulfate, copper formate, or combinations thereof.
摘要翻译：在一些实施方案中，物质组合物包括阿立哌唑，选自镁，锌，钠，锂，铁或其合金或其组合的金属和选自以下的铜盐：由碘化铜，氯化铜，溴化铜，硫酸铜，甲酸铜或其组合构成的组。

3. 发明申请

WO2017155093A1 SYNERGISTIC FUNGICIDAL COMPOSITION FOR CONTROLLING PLANT DISEASES 审中-公开
标题翻译：用于控制植物病害的协同杀真菌组合物
公开(公告)号：WO2017155093A1
公开(公告)日：2017-09-14
申请号：PCT/JP2017/009717
申请日：2017-03-10
申请人： SUMITOMO CHEMICAL COMPANY, LIMITED
发明人： KIGUCHI, So
IPC分类号： A01N37/52 , A01N43/58 , A01N43/78 , A01N25/04 , A01N25/14 , A01P3/00 , A01N25/00
CPC分类号： A01N43/58 , A01N37/52 , A01N43/78 , A01N25/00 , A01N25/04 , A01N25/14
摘要： The present invention provides a composition for controlling a plant disease comprising a pyridazine compound represented by formula (1) wherein X represents a fluoro atom or a hydrogen atom, and at least one amidine compound selected from the following group (A), and a method for controlling a plant disease, comprising a step of applying each effective amount of the above-mentioned pyridazine compound represented by the formula (1) and the at least one amidine compound selected from the following group (A) to a plant or soil for cultivating the plant, Group (A): a group consisting of N'-{4-[(4,5-dichlorothiazol-2-yl)oxy]-2,5-dimethylphenyl}-N-ethyl-N-methylmethane imidamide and N'-(2,5-dimethyl-4-phenoxyphenyl)-N-ethyl-N-methylmethane imidamide, the composition and method having excellent control efficacies against plant diseases.
摘要翻译：本发明提供了用于防治植物病害的组合物，其包含式（1）代表的哒嗪化合物和其中X代表氟原子或氢原子的哒嗪化合物和至少一种选自以下的脒化合物（1）所述的哒嗪化合物以及选自下述组中的至少一种脒化合物的步骤（A），以及控制植物病害的方法，所述方法包括将有效量的上述式（1）（A）组：由N' - {4 - [（4,5-二氯噻唑-2-基）氧基] -2,5-二甲基苯基} -N- N-乙基-N-甲基甲烷亚胺酰胺和N' - （2,5-二甲基-4-苯氧基苯基）-N-乙基-N-甲基甲烷亚胺酰胺，该组合物和方法对植物病害具有优异的防治效果。

4. 发明申请

WO2017155088A1 SYNERGISTIC FUNGICIDAL COMPOSITION FOR CONTROLLING PLANT DISEASES 审中-公开
标题翻译：用于控制植物病害的协同杀真菌组合物
公开(公告)号：WO2017155088A1
公开(公告)日：2017-09-14
申请号：PCT/JP2017/009712
申请日：2017-03-10
申请人： SUMITOMO CHEMICAL COMPANY, LIMITED
发明人： KIGUCHI, So
IPC分类号： A01N43/56 , A01N37/38 , A01N25/00 , A01N25/04 , A01N25/14 , A01P3/00
摘要： The present invention provides a composition for controlling a plant disease comprising a compound represented by formula (1), and a compound represented by formula (2), and a method for controlling a plant disease, comprising a step of applying each effective amount of the compound represented by the above formula (1) and the compound represented by the above formula (2) to a plant or soil for cultivating the plant, the composition and method having excellent control efficacies against plant diseases.
摘要翻译：本发明提供用于防治植物病害的组合物，其包含由式（1）表示的化合物和由式（2）表示的化合物，以及用于防治植物病害的方法，所述组合物包含将有效量的上述式（1）所示的化合物和上述式（2）所示的化合物分别施用于栽培植物的植物或土壤的工序，对植物病害具有优异的防除效果的组合物和方法。

5. 发明申请

WO2017104140A1 METHOD FOR PRODUCING BETA-SIALON FLUORESCENT MATERIAL 审中-公开
标题翻译：生产β-Sialon荧光材料的方法
公开(公告)号：WO2017104140A1
公开(公告)日：2017-06-22
申请号：PCT/JP2016/005147
申请日：2016-12-15
申请人： NICHIA CORPORATION
发明人： MORIKAWA, Motoharu , HOSOKAWA, Shoji
IPC分类号： C09K11/08 , C09K11/64
CPC分类号： C09K11/7734 , C09K11/0883
摘要： A method for producing β-sialon fluorescent material having excellent emission intensity is provided. The method for producing β-sialon fluorescent material includes providing a composition comprising silicon nitride that contains aluminium, an oxygen atom, and europium, heat treating the composition, and contacting the heat-treated composition with a basic substance.
摘要翻译：提供了具有优异发光强度的β-赛伦荧光体的制造方法。 β-赛隆荧光体的制造方法包括：提供包含含有铝，氧原子和铕的氮化硅的组合物，对组合物进行加热处理，使热处理后的组合物与碱性物质接触的组合物。

6. 发明申请

WO2017061127A1 LIGHT-EMITTING DEVICE, INTEGRATED LIGHT-EMITTING DEVICE, AND LIGHT-EMITTING MODULE 审中-公开
标题翻译：发光装置，集成发光装置和发光模块
公开(公告)号：WO2017061127A1
公开(公告)日：2017-04-13
申请号：PCT/JP2016/004528
申请日：2016-10-07
申请人： NICHIA CORPORATION
发明人： YAMADA, Motokazu , YAMADA, Yuichi
IPC分类号： H01L33/58 , H01L33/10 , H01L33/54
CPC分类号： H01L25/0753 , F21V7/00 , F21V9/08 , F21V23/002 , F21Y2115/10 , G02F1/133603 , G02F1/133605 , G02F2001/133614 , H01L33/46 , H01L33/505 , H01L33/507 , H01L33/54 , H01L33/56 , H01L33/58 , H01L33/60 , H01L33/62 , H01L2224/16225 , H01L2924/181 , H01L2924/00012
摘要： A light-emitting device includes a base including a conductive wiring; a light-emitting element mounted on the base and configured to emit light; a light reflective film provided on an upper surface of the light-emitting element; and a encapsulant covering the light-emitting element and the light reflective film. A ratio (H/W) of a height (H) of the encapsulant to a width (W) of a bottom surface of the encapsulant is less than 0.5.
摘要翻译：发光装置包括：基底，其包括导电布线; 安装在所述基座上并被配置为发光的发光元件; 设置在所述发光元件的上表面上的光反射膜; 以及覆盖发光元件和光反射膜的密封剂。密封剂的高度（H）与密封剂的底面的宽度（W）的比（H / W）小于0.5。

7. 发明申请

WO2017022236A1 AQUEOUS BONDING COMPOSITION 审中-公开
标题翻译：水性粘结组合物
公开(公告)号：WO2017022236A1
公开(公告)日：2017-02-09
申请号：PCT/JP2016/003545
申请日：2016-08-02
申请人： HENKEL AG & CO. KGAA
发明人： KAKUDA, Atsushi , YOSHIDA, Yoshio
IPC分类号： B27N3/00 , C09D105/00 , C08L97/02
CPC分类号： C09J105/00 , B27N3/002 , B27N7/005 , B32B21/04 , C08K3/28 , C08K3/32 , C08K5/17 , C08K2003/321 , C08L97/02 , C09D105/00 , C09J2203/10 , C08L5/00
摘要： Disclosed is an aqueous bonding composition comprising: (A) a saccharide; (B) a phosphate; and (C) at least one neutralizing agent selected from ammonia and an amine compound having at least one hydroxyl group. The aqueous bonding composition is excellent in balance among bending strength, bending strength under wet condition, water-absorption thickness expansion coefficient and peeling strength and scarcely causes metal to rust. The aqueous bonding composition can be usefully used to produce a wood-based material.
摘要翻译：公开了含水粘合组合物，其包含：（A）糖; （B）磷酸盐; 和（C）至少一种中和剂，其选自氨和具有至少一个羟基的胺化合物。水性粘合组合物在弯曲强度，湿条件下的弯曲强度，吸水厚度膨胀系数和剥离强度之间的平衡优异，并且几乎不会使金属生锈。水性粘合组合物可用于生产木质材料。

8. 发明申请

WO2016189877A1 UREA DERIVATIVE OR PHARMACOLOGICALLY ACCEPTABLE SALT THEREOF 审中-公开
标题翻译：尿素衍生物或药理学上可接受的盐
公开(公告)号：WO2016189877A1
公开(公告)日：2016-12-01
申请号：PCT/JP2016/002559
申请日：2016-05-26
申请人： KYORIN PHARMACEUTICAL CO., LTD.
发明人： TAKAHASHI, Hiroyasu , WATANABE, Hiroyuki , FUJII, Kiyoshi , SHIBASAKI, Mitsuhito , KAWASHIMA, Mikako , KAMIYA, Megumi , OHATA, Kohei
IPC分类号： C07C275/50 , C07D311/58 , C07D231/12 , C07D333/16 , C07D333/28 , C07D239/36 , C07D413/04 , C07D413/12 , C07D417/12 , C07D249/04 , C07D249/08 , C07D249/12 , C07D257/04 , C07D261/08 , C07D263/32 , C07D263/34 , C07D271/06 , C07D271/07 , C07D271/10 , C07D271/113 , C07D273/04 , C07D277/28 , C07D285/08 , C07D285/12 , C07D285/135 , C07D213/61 , C07D307/79 , A61K31/415 , A61K31/4192 , A61K31/421 , A61K31/4245 , A61K31/433 , A61K31/44 , A61K31/381 , A61K31/353 , A61K31/343 , A61K31/5395 , A61K31/5377 , A61K31/41 , A61K31/454 , A61K31/42 , A61K31/513 , A61K31/427 , A61K31/428 , A61P29/00 , A61P35/00 , A61P37/00 , A61P31/18 , A61P25/00
CPC分类号： C07D257/04 , C07C275/30 , C07C275/42 , C07C275/50 , C07C311/51 , C07C317/32 , C07C317/40 , C07C2601/02 , C07D213/61 , C07D231/12 , C07D239/36 , C07D249/04 , C07D249/08 , C07D249/12 , C07D261/08 , C07D263/32 , C07D263/34 , C07D271/06 , C07D271/07 , C07D271/10 , C07D271/113 , C07D273/04 , C07D277/28 , C07D285/08 , C07D285/12 , C07D285/135 , C07D307/79 , C07D311/58 , C07D333/16 , C07D333/28 , C07D413/04 , C07D413/12 , C07D417/12
摘要： The present invention provides a urea compound or a pharmacologically acceptable salt thereof that has a formyl peptide receptor like 1 (hereinafter may be abbreviated as FPRL1) agonist effect, a pharmaceutical composition containing the urea compound or the pharmacologically acceptable salt thereof, and a pharmaceutical use thereof. It has been found that a urea derivative represented by the general formula (I) below or a pharmacologically acceptable salt thereof has a superior FPRL1 agonist effect. Compound (I) or a pharmacologically acceptable salt thereof is highly useful for treatment, prevention, or suppression of inflammatory diseases, chronic airway diseases, cancers, septicemia, allergic symptoms, HIV retrovirus infection, circulatory disorders, neuroinflammation, nervous disorders, pains, prion diseases, amyloidosis, immune disorders and the like.
摘要翻译：本发明提供具有甲酰基肽受体1（以下简称为FPRL1）激动剂效果的尿素化合物或其药理学上可接受的盐，含有脲化合物或其药理学可接受的盐的药物组合物和药物用途它们。已经发现，由下述通式（I）表示的尿素衍生物或其药理学上可接受的盐具有优异的FPRL1激动剂效果。化合物（I）或其药理学上可接受的盐对于治疗，预防或抑制炎性疾病，慢性气道疾病，癌症，败血病，过敏症状，HIV逆转录病毒感染，循环障碍，神经炎症，神经障碍，疼痛，朊病毒疾病，淀粉样变性，免疫障碍等。

9. 发明申请

WO2016042775A1 TRICYCLIC DERIVATIVE 审中-公开
公开(公告)号：WO2016042775A1
公开(公告)日：2016-03-24
申请号：PCT/JP2015/004781
申请日：2015-09-17
申请人： SUNOVION PHARMACEUTICALS INC. , SUMITOMO DAINIPPON PHARMA CO., LTD.
发明人： BURDI, Douglas F. , TANAKA, Daisuke , FUJII, Yuki , KAWASUMI, Muneo
IPC分类号： C07D487/14 , A61K31/519 , A61K31/53 , A61P25/00 , A61P25/16 , A61P25/18 , A61P25/28 , A61P43/00 , C07D498/14
CPC分类号： A61K31/519 , A61K31/53 , C07D471/14 , C07D487/14 , C07D498/14
摘要： Disclosed are compounds useful as inhibitors of phosphodiesterase 1 (PDE1), compositions thereof, and methods of using the same.
摘要翻译：公开了可用作磷酸二酯酶1（PDE1）抑制剂的化合物，其组合物及其使用方法。

10. 发明申请

WO2016038895A1 FLAVIVIRUS VIRUS LIKE PARTICLE 审中-公开
标题翻译： FLAVIVIRUS病毒样颗粒
公开(公告)号：WO2016038895A1
公开(公告)日：2016-03-17
申请号：PCT/JP2015/004623
申请日：2015-09-10
申请人： VLP THERAPEUTICS, LLC , AKAHATA, Wataru , UENO, Ryuji
发明人： AKAHATA, Wataru , UENO, Ryuji
IPC分类号： C12N15/09 , C07K19/00
CPC分类号： A61K39/12 , A61K2039/5258 , A61K2039/53 , A61K2039/575 , C07K14/005 , C12N7/00 , C12N2770/24023 , C12N2770/24123 , C12N2770/24134 , Y02A50/386 , Y02A50/388 , Y02A50/39 , Y02A50/394 , Y02A50/396
摘要： The present application provides a virus like particle comprising one or more flavivirus structural proteins, and a composition or vaccine comprising thereof, its use in the prevention or treatment of flavivirus infection. The flavivirus structural protein contains at least one amino acid alteration in the envelope region. Examples of flavivirus contains dengue virus.
摘要翻译：本申请提供了包含一种或多种黄病毒结构蛋白的病毒样颗粒及其组合物或疫苗，其用于预防或治疗黄病毒感染。黄病毒结构蛋白在包膜区含有至少一个氨基酸改变。黄病毒的实例包含登革热病毒。

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