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1. 发明申请

WO2020074733A1 EXTRACORPOREAL BLOOD TREATMENT APPARATUS AND METHOD FOR MONITORING PRESSURES IN AN EXTRACORPOREAL BLOOD TREATMENT APPARATUS 审中-公开
公开(公告)号：WO2020074733A1
公开(公告)日：2020-04-16
申请号：PCT/EP2019/077662
申请日：2019-10-11
申请人： GAMBRO LUNDIA AB
发明人： POUCHOULIN, Dominique , KARLSSON, David
IPC分类号： A61M1/36
摘要： An extracorporeal blood treatment apparatus, comprises: at least a pressure sensor (24, 25) located in a respective measurement site on an extracorporeal blood circuit (6, 7); an electronic control unit (23) operatively connected at least to the pressure sensor (24, 25). The electronic control unit (23) is configured to perform at least the following procedure: receiving from the pressure sensor (24, 25) a signal correlated to a measured blood pressure (Plmeasured, P2measured) in the measurement site; correcting the blood measured pressure (Plmeasured, P2measured) through a mathematical correction model to obtain a blood actual pressure (Pinlet, Poutlet) in a reference site other than the measurement site. Between the reference site and the measurement site, a circuit section and, optionally, at least one additional device (18, 27, 28) is/are positioned. The mathematical correction model is a model of a pressure drop in the circuit section and, optionally, in the additional device (18, 27, 28).

2. 发明申请

WO2019129719A1 APPARATUS FOR EXTRACORPOREAL BLOOD TREATMENT 审中-公开
公开(公告)号：WO2019129719A1
公开(公告)日：2019-07-04
申请号：PCT/EP2018/086631
申请日：2018-12-21
申请人： GAMBRO LUNDIA AB
发明人： COURT, Thierry , POUCHOULIN, Dominique
IPC分类号： A61M1/34 , A61M1/36
CPC分类号： A61M1/3646 , A61M1/3431 , A61M1/3649
摘要： An apparatus (1) for CRRT is provided comprising a blood circuit (10, 20, 30, 60) with a blood removal line (20), a treatment unit (10), and a blood return line (30). A replacement fluid container (78) is configured for containing a medical fluid, a pre-infusion line (70) has a first end (70-1) connected to the replacement fluid container (78) and a second end (70-2) connected to the blood removal line (20) and a blood pump (22) is active on the blood circuit. A replacement fluid pump (72) is active on the pre-infusion line (70), a dialysate circuit (40, 50, 70) comprises an effluent line (50) configured for discharging fluid from the second chamber, and a control unit (80) is connected to the replacement fluid pump (72) and to the blood pump (22) and is configured for performing a rinse-back procedure for restituting blood to a patient. The rinse-back procedure comprises conveying blood contained in the blood circuit (10, 20, 30, 60) towards the second end (30-2) of the blood return line (30) using the medical fluid.

3. 发明申请

WO2018130417A1 EXTRACORPOREAL BLOOD TREATMENT APPARATUS AND METHOD FOR CHECKING THE CONNECTION OF A SOFT BAG IN AN EXTRACORPOREAL BLOOD TREATMENT APPARATUS. 审中-公开
公开(公告)号：WO2018130417A1
公开(公告)日：2018-07-19
申请号：PCT/EP2017/084823
申请日：2017-12-29
申请人： GAMBRO LUNDIA AB
发明人： FRUGIER, Alain
IPC分类号： A61M1/14 , A61M1/16 , A61M1/34 , A61M1/36
摘要： An extracorporeal blood treatment apparatus (1) and a method for checking the connection of a soft bag (30, 24; 33, 34) in the apparatus (1). The apparatus (1) comprises a blood treatment device (2), an extracorporeal blood circuit (3, 5) and a fluid circuit (8, 12, 15, 17, 18, 22; 41, 42, 44). A control unit (32) is configured to check the connection of a soft bag (30, 24; 33, 34) to the extracorporeal blood circuit (3, 5) or to the fluid circuit (22; 41, 42, 44) through the following procedure: sucking a medium from a connecting zone (29) through a blood pump (6) or a fluid pump (23; 37, 39) of the apparatus (1); measuring at least a pressure trend (P1, P1 - P2, P2 - PI, Pwdr, Pwdr - Pret, Pret - Pwdr) over time in the extracorporeal blood circuit (3, 5) or in the fluid circuit (22; 41, 42, 44) through at least a pressure sensor (25, 26); establishing from said measured pressure trend (P1, P1 - P2, P2 - PI, Pwdr, Pwdr - Pret, Pret - Pwdr) if the soft bag (30, 24; 33, 34) is connected to the extracorporeal blood circuit (3, 5) or to the fluid circuit (22; 41, 42, 44) at the connecting zone (29).

4. 发明申请

WO2018116037A1 TAMPER-EVIDENT CONTAINER AND PROCESS OF MAKING THE SAME 审中-公开
公开(公告)号：WO2018116037A1
公开(公告)日：2018-06-28
申请号：PCT/IB2017/057536
申请日：2017-11-30
申请人： I.G.B. S.R.L.
发明人： BRESSAN, Alessio , BRESSAN, Michel , GANDOLLA, Alberto
IPC分类号： B65D5/02 , B65D55/02 , G08B13/12
摘要： The present invention refers to a tamper-evident container (1) comprising: a store (2) defining an internal volume (3) and exhibiting a passage opening (5) delimited by a free edge (6); a closure system (7) engaged at the free edge (6) and movable with respect to the store (2) between a closing condition and an opening one; an electric circuit (30) connected to the store (2) and defined at least partially on the closure system (7). The electric circuit (30) is configured for determining at least one between an electric property and a physical property of the electric circuit (30) itself following at least one first closure of the closure system (7). The present invention further refers to a process of making the container (1).

5. 发明申请

WO2018019926A1 APPARATUS FOR EXTRACORPOREAL TREATMENT OF BLOOD 审中-公开
标题翻译：用于体液处理的装置
公开(公告)号：WO2018019926A1
公开(公告)日：2018-02-01
申请号：PCT/EP2017/068983
申请日：2017-07-27
申请人： GAMBRO LUNDIA AB
发明人： POUCHOULIN, Dominique
IPC分类号： A61M1/16 , A61M1/34 , A61M1/36
摘要： An extracorporeal blood treatment apparatus comprises a blood treatment device (2), an extracorporeal blood circuit, a blood pump (8) configured to be coupled to a blood withdrawal line (6) of the extracorporeal blood circuit. A closed fluid line (10) is connected to an inlet port (4a) and to an outlet port (4b) of a fluid chamber (4) of the blood treatment device (2), wherein the closed fluid line (10) together with the fluid chamber (4) forms a recirculation loop. An evacuation line (15) departs from the closed fluid line (10). A warming device (13) and a recirculation pump (17) are coupled or configured to be coupled to the closed fluid line (10). At least one temperature sensor (22) is operative on the extracorporeal blood circuit and it is configured to sense a blood temperature (Tb). A control unit (25), connected to the warming device (13), to the recirculation pump (17) and to the temperature sensor (22), is configured to execute the following procedure: receiving from the temperature sensor (22) at least a signal correlated to the blood temperature (Tb); adjusting the blood temperature (Tb) by controlling at least one of the warming device (13) and the recirculation pump (17).
摘要翻译：一种体外血液处理设备，包括血液处理装置（2），体外血液回路，血液泵（8），血液泵（8）被配置为与体外血液回路（6）的血液抽取管线。封闭的流体管线（10）连接到血液处理装置（2）的流体腔室（4）的入口端口（4a）和出口端口（4b），其中封闭的流体管线（10）与流体室（4）形成再循环回路。排出管线（15）从封闭流体管线（10）出发。加温装置（13）和再循环泵（17）联接或构造成联接到封闭流体管线（10）。至少一个温度传感器（22）在体外血液回路上操作并且被配置为感测血液温度（Tb）。连接到加温装置（13），再循环泵（17）和温度传感器（22）的控制单元（25）被配置为执行以下过程：从温度传感器（22）接收至少一个与血液温度（Tb）相关的信号; 通过控制加温装置（13）和再循环泵（17）中的至少一个来调整血液温度（Tb）。

6. 发明申请

WO2017182901A1 FOLDING DEVICE, FOLDING PLANT, AND PROCESS OF FOLDING 审中-公开
标题翻译：折叠设备，折叠设备和折叠过程
公开(公告)号：WO2017182901A1
公开(公告)日：2017-10-26
申请号：PCT/IB2017/051862
申请日：2017-03-31
申请人： I.G.B. S.R.L.
发明人： BRESSAN, Michel , GANDOLLA, Alberto , BRESSAN, Alessio
IPC分类号： B31B50/00 , B31B50/585 , B31B50/36
CPC分类号： B31B50/00 , B31B50/262 , B31B50/36 , B31B50/585 , B31B2100/00 , B31B2110/35
摘要： The present invention refers to a folding device (1) for semi-finished products (50) of sheet material moving along a predetermined advancement direction (A). The folding device comprises: a supporting frame (2), a lower tool (3) comprising at least one base portion (4) which has a supporting surface (5) configured for receiving and supporting the moving semi-finished product (50) and a lower blowing device (6) configured for ejecting a gas flow towards the moving semi-finished product (50) along the advancement direction (A) and for enabling a first fold of at least one longitudinal end sheet (60) of the semi-finished product (50). Moreover, the folding device comprises an upper tool (9) substantially facing the lower tool (3) along a gas flow emission direction from the lower blowing device (6), the upper tool (9) comprises a guiding element (10) having a descending section (10a) configured for developing by approaching to the lower tool (3) along the advancement direction (A) of the semi-finished product (50). The guiding element (10) is configured for contacting the longitudinal end sheet folded by the lower blowing device (6) for enabling a further fold of said longitudinal end sheet (60).
摘要翻译：本发明涉及一种用于沿预定前进方向（A）移动的片材半成品（50）的折叠装置（1）。所述折叠装置包括：支撑框架（2）;下部工具（3），所述下部工具包括至少一个基部（4），所述基部具有构造成用于接收和支撑移动的半成品（50）的支撑表面（5）;以及下吹风装置（6），所述下吹风装置构造成用于沿着所述前进方向（A）向所述移动的半成品（50）喷射气流并且用于使所述半成品（50）的至少一个纵向端片（60）成品（50）。此外，折叠装置包括上部工具（9），该上部工具沿着来自下部吹风装置（6）的气流排放方向基本面向下部工具（3），上部工具（9）包括引导元件（10），该引导元件具有下降部分（10a），所述下降部分（10a）被配置成通过沿着半成品（50）的前进方向（A）接近下部工具（3）而显影。引导元件（10）构造成用于接触由下部吹塑装置（6）折叠的纵向端部片材，以使所述纵向端部片材（60）能够进一步折叠。

7. 发明申请

WO2015159174A1 CONTAINER FOR DELIVERING A PREFIXED NUMBER OF PRODUCTS AT A TIME AND A PROCESS FOR MAKING OF SAID CONTAINER 审中-公开
标题翻译：用于在时间上交付前期产品数量的集装箱和制造集装箱的过程
公开(公告)号：WO2015159174A1
公开(公告)日：2015-10-22
申请号：PCT/IB2015/052399
申请日：2015-04-01
申请人： I.G.B. S.R.L.
发明人： BRESSAN, Michel , GANDOLLA, Alberto
IPC分类号： B65D5/72 , B65D83/04
CPC分类号： B65D83/0409 , A61J7/0076 , B65D5/723 , B65D85/60
摘要： The present invention relates to a container (1) for delivering a specific number of products (P) at a time, said container (1) comprising: a storehouse (2) defining an inner volume (3) configured for housing a plurality of products (P), a volume of passage (4) exhibiting at least one outlet (5) configured for enabling to deliver said products (P) outside the container (1), a door (6) defining an outlet (7) configured for communicating the storehouse (2) with the volume of passage (4), a delivery mechanism (8) placed at the door (6), and configured for managing the passage of products (P) through this latter. The delivery mechanism (8) is configured for being arranged in a closed condition in which the mechanism itself prevents the product (P) passage from the door (6), the delivery mechanism (8) is further configured for being arranged in a passage condition in which the mechanism itself enables one or plural products (P) to pass from the door (6); the delivery mechanism (8) comprises: a shutter (9) and a maneuvering organ (10) active on the shutter (9) for commanding the closure and passage conditions of the delivery mechanism (8). The shutter (9) comprises a folded portion (11) of sheet material.
摘要翻译：本发明涉及一次用于输送特定数量的产品（P）的容器（1），所述容器（1）包括：仓库（2），其限定内部容积（3），其被构造成容纳多个产品（P），具有构造成能够将所述产品（P）输送到所述容器（1）外部的至少一个出口（5）的通道体积（4）;限定出口（7）的门（6），所述出口构造成用于连通具有通道体积（4）的仓库（2），放置在门（6）处的输送机构（8），并且构造成用于管理产品（P）通过该通道。输送机构（8）被构造成布置在闭合状态，其中机构本身防止产品（P）从门（6）通过，输送机构（8）还被构造成布置成通过状态其中机构本身使一个或多个产品（P）从门（6）通过; 输送机构（8）包括：快门（9）和活动在快门（9）上的操纵器官（10），用于指示输送机构（8）的关闭和通过状态。快门（9）包括片材的折叠部分（11）。

8. 发明申请

WO2015091082A1 AN APPARATUS FOR EXTRACORPOREAL BLOOD TREATMENT AND A CONTROL METHOD THEREFOR 审中-公开
标题翻译：用于提取血液治疗的装置及其控制方法
公开(公告)号：WO2015091082A1
公开(公告)日：2015-06-25
申请号：PCT/EP2014/076956
申请日：2014-12-09
申请人： GAMBRO LUNDIA AB
发明人： SOLEM, Kristian , STEFANI, David , HOBRO, Sture , OLDE, Bo
IPC分类号： A61M1/36 , G01F23/14
CPC分类号： A61M1/3627 , A61M1/3624 , A61M1/3626 , A61M1/367 , A61M2205/123 , A61M2205/3331 , A61M2205/3386 , A61M2205/3389 , G01F23/14 , G01F23/18
摘要： An apparatus (1) is described for extracorporeal blood treatment, comprising a treatment unit (2), an extracorporeal blood circuit (8) and a fluid evacuation line (10). A venous chamber (12) is placed in a blood return line (7) and isarranged in use to contain a gas in an upper portion (120) and blood at a predetermined level in a lower portion. The apparatus (1) comprises a control unit (21) connected to a first pressure sensor (14) and configured to: receive from the first pressure sensor (14) a first signal (P1(t)) relating to a time variable pressure (P(t)) of the blood flow; calculate a phase shift (θ) between the first signal (P1(t)) and a reference signal (P2(t)) correlated to the time variable pressure (P(t)) detected at a location distinct from the upper portion (120) of the chamber (12); monitorthe volume (V) of gas in the upper portion (120) of the chamber (12)through the phase shift (θ).
摘要翻译：一种用于体外血液处理的装置（1），其包括处理单元（2），体外血液回路（8）和排液管线（10）。静脉腔室（12）被放置在血液回流管线（7）中，并且在使用中被排列成在上部（120）中容纳气体，并在下部含有预定水平的血液。装置（1）包括连接到第一压力传感器（14）并被配置为：从第一压力传感器（14）接收与时间可变压力相关的第一信号（P1（t））的控制单元（21） P（t））; 计算第一信号（P1（t））和与在与上部不同的位置处检测到的时间可变压力（P（t））相关的参考信号（P2（t））之间的相移（θ））; 通过相移（θ）在腔室（12）的上部（120）中的气体的单调体积（V）。

9. 发明申请

WO2014083450A1 HEMODIALYSIS ON-LINE PORT LEAK DETECTION 审中-公开
标题翻译： HEMODIALYSIS在线端口泄漏检测
公开(公告)号：WO2014083450A1
公开(公告)日：2014-06-05
申请号：PCT/IB2013/059784
申请日：2013-10-30
申请人： GAMBRO LUNDIA AB
发明人： ZANINI, Marco , DINU, Marius
IPC分类号： A61M1/36
CPC分类号： A61M1/14 , A61M1/34 , A61M1/342 , A61M1/367 , A61M2205/15 , A61M2205/18 , A61M2205/702 , B01D61/32 , G08B21/20
摘要： Extracorporeal blood treatment apparatus and methods as described herein involve on-line port leak detection.
摘要翻译：如本文所述的体外血液处理装置和方法涉及在线端口泄漏检测。

10. 发明申请

WO2014076601A1 APPARATUS FOR DETERMINING A PARAMETER INDICATIVE OF THE PROGRESS OF AN EXTRACORPOREAL BLOOD TREATMENT 审中-公开
标题翻译：用于确定提取物血液处理进展的参数的装置
公开(公告)号：WO2014076601A1
公开(公告)日：2014-05-22
申请号：PCT/IB2013/059711
申请日：2013-10-28
申请人： GAMBRO LUNDIA AB
发明人： FONTANAZZI, Francesco , ROSATI, Francesco , SURACE, Alessandro
IPC分类号： A61M1/16
CPC分类号： A61M1/367 , A61M1/16 , A61M1/1607 , A61M1/1609 , A61M1/1613 , A61M1/1617 , A61M2205/3317 , A61M2205/3324 , A61M2205/3334 , A61M2205/3393 , A61M2209/02 , G05B13/04 , G05D7/0617 , G06F17/10
摘要： An apparatus for extracorporeal treatment of blood (1) comprising a treatment unit, a blood withdrawal line, a blood return line, a preparation line and a spent dialysate line. A control unit (10) is configured to calculate values of a parameter relating to treatment effectiveness based on measures of the conductivity in the spent dialysate line. The value of the effectiveness parameter is calculated using one or more values representative of the conductivity in the spent dialysate line obtained relying on a mathematical model.
摘要翻译：一种用于体外血液处理的装置（1），包括处理单元，抽血管线，血液回流管线，制备管线和用过的透析液管线。控制单元（10）被配置为基于用过的透析液线中的电导率的测量来计算与治疗有效性有关的参数的值。使用代表根据数学模型获得的用过的透析液线中的电导率的一个或多个值来计算有效性参数的值。

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