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1. 发明申请

WO2006050526A1 METHODS FOR DATA RETENTION IN AN IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：可移植医疗器械中数据保持的方法
公开(公告)号：WO2006050526A1
公开(公告)日：2006-05-11
申请号：PCT/US2005/040194
申请日：2005-11-02
申请人： MEDTRONIC, INC. , DREW, Touby, A.
发明人： DREW, Touby, A.
IPC分类号： A61B5/00
CPC分类号： A61B5/4094 , A61B5/0006 , A61B5/0031 , A61B5/02055 , A61B5/021 , A61B5/024 , A61B5/031 , A61B5/04001 , A61B5/04012 , A61B5/0402 , A61B5/0476 , A61B5/0816 , A61B5/1118 , A61B5/165 , A61B5/4082 , A61B5/686 , A61B5/7232 , A61B5/7282 , A61N1/36132 , A61N1/36135 , A61N1/36521 , A61N1/36585 , A61N1/3702 , A61N1/37252 , A61N1/37282 , G06F17/30336 , G06F19/00 , G06F19/3418 , G16H10/60 , G16H40/63
摘要： Methods for storing data records associated with a medical monitoring event in a data structure [1600]. An implanted device [100] obtains data and stores the data in the data record in a first data structure [1601] that is age-based. Before an oldest data record is lost, the oldest data record may be stored in a second data structure [1602] that is priority index-based. The priority index may be determined by a severity level and may be further determined by associated factors. The implanted device [100] may organize, off-load, report, and/or display a plurality of data records based on an associated priority index. Additionally, the implanted device [100] may select a subset or composite of physiologic channels from the available physiologic channels based on a selection criterion.
摘要翻译：用于在数据结构中存储与医疗监视事件相关联的数据记录的方法[1600]。植入装置[100]以基于年龄的第一数据结构[1601]获得数据并将数据存储在数据记录中。在最旧的数据记录丢失之前，最早的数据记录可以存储在基于优先级索引的第二数据结构[1602]中。优先权索引可以由严重性级别确定，并且可以由相关因素进一步确定。植入装置[100]可以基于相关联的优先级索引来组织，卸载，报告和/或显示多个数据记录。另外，植入装置[100]可以基于选择标准从可用的生理通道中选择生理通道的子集或复合物。

2. 发明申请

WO2004034998A2 CONTROL OF TREATMENT THERAPY DURING START-UP AND DURING OPERATION OF A MEDICAL DEVICE SYSTEM 审中-公开
标题翻译：医疗器械系统启动和运行期间治疗治疗的控制
公开(公告)号：WO2004034998A2
公开(公告)日：2004-04-29
申请号：PCT/US2003/032868
申请日：2003-10-15
申请人： MEDTRONIC INC. , OSORIO, Ivan , FREI, Mark, G. , CARLSON, David, L.
发明人： OSORIO, Ivan , FREI, Mark, G. , CARLSON, David, L.
IPC分类号： A61K
CPC分类号： A61N1/37235 , A61B5/4094 , A61B5/725 , A61N1/36014 , A61N1/36025 , A61N1/36082 , A61N1/36135 , A61N1/37229
摘要： A method and medical device system for controlling treatment therapy delivered to treat a nervous system disorder. During start-up, the medical device system prevents the therapy device from delivering therapy to the patient for a predetermined time period after the therapy device has been activated. During operation, before the therapy device is programmed, the system performs a check on the programming information to ensure that the programming information will result in treatment therapy being within of an acceptable range of one or more therapy parameters.
摘要翻译：一种用于治疗输送治疗神经系统疾病的治疗疗法的方法和医疗装置系统。在启动期间，医疗装置系统防止治疗装置在治疗装置被激活之后的预定时间段内向患者递送治疗。在操作期间，在治疗装置被编程之前，系统对编程信息进行检查，以确保编程信息将导致治疗疗法在一个或多个治疗参数的可接受范围内。

3. 发明申请

WO2004034997A2 MEDICAL DEVICE SYSTEM WITH RELAYING MODULE FOR TREATMENT OF NERVOUS SYSTEM DISORDERS 审中-公开
标题翻译：具有用于治疗神经系统疾病的继电器模块的医疗装置系统
公开(公告)号：WO2004034997A2
公开(公告)日：2004-04-29
申请号：PCT/US2003/032867
申请日：2003-10-15
申请人： MEDTRONIC INC. , RISE, Mark, T. , DONDERS, Adrianus, P. , SCHAFFNER, Scott, F.
发明人： RISE, Mark, T. , DONDERS, Adrianus, P. , SCHAFFNER, Scott, F.
IPC分类号： A61K
CPC分类号： A61N2/00 , A61N1/08 , A61N1/32 , A61N1/36082 , A61N1/36135 , A61N1/37229 , A61N1/37252
摘要： Apparatus and method facilitates communications between an implanted component and an external component of a medical device system through a relaying module. The medical device system provides treatment to a patient for a nervous system disorder. The relaying module (which may be worn by the patient) provides telemetry channels between the implanted component and the relaying module and between the telemetry module and the external component. With an implantable configuration the implanted component comprises a monitoring element, a treatment therapy unit, an interfacing unit, and a processing unit, and the external component comprises a programmer. With a hybrid configuration the implanted component comprises a monitoring element, a treatment delivery unit, and an interfacing unit, and the external component comprises a processing unit. With an external configuration, the implanted component comprises a monitoring element and a treatment delivery unit, and the external component comprises an interfacing unit and a processing unit.
摘要翻译：装置和方法通过中继模块便于植入部件与医疗装置系统的外部部件之间的通信。医疗装置系统为患者提供神经系统障碍的治疗。中继模块（可由患者佩戴）提供植入部件和中继模块之间以及遥测模块和外部组件之间的遥测通道。通过植入式构造，植入部件包括监测元件，治疗治疗单元，接口单元和处理单元，并且外部部件包括程序员。通过混合配置，植入部件包括监视元件，治疗传递单元和接口单元，并且外部部件包括处理单元。通过外部配置，植入部件包括监视元件和治疗传递单元，并且外部部件包括接口单元和处理单元。

4. 发明申请

WO2004034881A2 SIGNAL QUALITY MONITORING AND CONTROL FOR A MEDICAL DEVICE SYSTEM 审中-公开
标题翻译：医疗设备系统的信号质量监测与控制
公开(公告)号：WO2004034881A2
公开(公告)日：2004-04-29
申请号：PCT/US2003/032938
申请日：2003-10-15
申请人： MEDTRONIC INC. , FREI, Mark, G. , OSORIO, Ivan , WERDER, Jonathan, C. , CARLSON, David, L.
发明人： FREI, Mark, G. , OSORIO, Ivan , WERDER, Jonathan, C. , CARLSON, David, L.
IPC分类号： A61B
CPC分类号： A61N1/37252 , A61B5/04012 , A61B5/048 , A61B5/4094 , A61N1/36014 , A61N1/36064 , A61N1/36082 , A61N1/3702 , A61N1/37229
摘要： Method and apparatus for detecting possible interference in a neurological signal received from a monitoring element of a medical device system. The monitoring element monitors a condition or a symptom of a nervous system disorder being treated and provides a neurological signal to the medical device system for purposes of providing closed-loop feedback control. The system analyzes various parameters of the received signal by taking instantaneous measurements of data points in moving window and thereby determining whether the signal is of poor quality. If the signal is of determined poor quality, it is removed from consideration in the closed-loop feedback control system until it is determined that the signal quality has sufficiently been restored.
摘要翻译：用于检测从医疗设备系统的监视元件接收的神经信号中可能的干扰的方法和设备。监测元件监测正在治疗的神经系统疾病的状况或症状，并为了提供闭环反馈控制的目的而向医疗设备系统提供神经信号。系统通过对移动窗口中的数据点进行瞬时测量来分析接收信号的各种参数，从而确定信号质量是否差。如果信号质量差，则在闭环反馈控制系统中将其从考虑中移除，直到确定信号质量已被充分恢复。

5. 发明申请

WO2004034879A2 SCREENING TECHNIQUES FOR MANAGEMENT OF A NERVOUS SYSTEM DISORDER 审中-公开
标题翻译：用于管理神经系统疾病的筛选技术
公开(公告)号：WO2004034879A2
公开(公告)日：2004-04-29
申请号：PCT/US2003/032906
申请日：2003-10-15
申请人： MEDTRONIC INC. , OSORIO, Ivan , FREI, Mark, G. , BHAVARAJU, Naresh, C. , PETERS, Thomas, E. , GRAVES, Nina, M. , SCHAFFNER, Scott, F. , GIFTAKIS, Jonathon, E. , RISE, Mark, T. , WERDER, Jonathan, C.
发明人： OSORIO, Ivan , FREI, Mark, G. , BHAVARAJU, Naresh, C. , PETERS, Thomas, E. , GRAVES, Nina, M. , SCHAFFNER, Scott, F. , GIFTAKIS, Jonathon, E. , RISE, Mark, T. , WERDER, Jonathan, C.
IPC分类号： A61B
CPC分类号： A61N1/08 , A61B5/0476 , A61B5/4094 , A61B5/7275 , A61N1/36025 , A61N1/36082 , A61N1/361 , A61N1/37217
摘要： Apparatus and method support a neurological event screening for a medical device. The medical device assists a user in determining a configuration of the medical device for delivering an effective treatment for a nervous system disorder. The medical device detects a neurological event, such as a seizure, and reports a neurological event focus location and a neurological event spread to the user. The user may use the information to provide a configuration of a therapeutic delivery unit and associated therapy parameters. Therapeutic treatment is delivered to the patient, and the medical device is provided an indication of the patient's acceptance to the treatment. The user may modify the configuration and therapy parameters in order to achieve efficacy and acceptance. Depending upon the patient's acceptance, therapy is applied in either an open loop mode or a closed loop mode. The medical device determines whether the treatment is successful in accordance with a criterion.
摘要翻译：装置和方法支持用于医疗装置的神经事件筛查。医疗装置帮助用户确定医疗装置的配置以递送用于神经系统障碍的有效治疗。医疗装置检测诸如癫痫发作的神经系统事件，并向用户报告神经系统事件焦点位置和神经系统事件。用户可以使用该信息来提供治疗递送单元的配置和相关联的治疗参数。向患者传送治疗性治疗，并且向患者提供患者接受治疗的指示。用户可以修改配置和治疗参数，以达到功效和验收。根据患者的接受程度，治疗以开环模式或闭环模式应用。医疗设备根据标准确定治疗是否成功。

6. 发明申请

WO2002103803A1 INP HETEROJUNCTION BIPOLAR TRANSISTOR WITH INTENTIONALLY COMPRESSIVLEY MISSMATCHED BASE LAYER 审中-公开
标题翻译： INP异质双极晶体管，具有明显的压缩基底层
公开(公告)号：WO2002103803A1
公开(公告)日：2002-12-27
申请号：PCT/US2002/019383
申请日：2002-06-18
申请人： EPIWORKS, INC.
发明人： HARTMANN, Quesnell
IPC分类号： H01L29/737
CPC分类号： H01L29/7378 , H01L29/7371
摘要： A heterojunction bipolar transistor (HBT) having a substrate formed of indium phospide (InP) and having emitter, base and collector layers formed over the substrate such that the base layer is disposed between the emitter and collector layers. The collector layer formed from InGaAs, and the collector layer being doped n-type. The emitter layer formed from InP, and the emitter layer bieng doped n-type. The base layer formed of indium gallium arsenide (InGaAs), the base layer being compressively mismatched, and doped p-type. A lattice mismatch between the substrate and the base material is greater than 0.2%. In an x-ray rocking curve of the heterojunction bipolar transistor, a peak corresponding to the base layer being separated from a peak corresponding to the substrate layer by at least -250 arcseconds. In one embodiment this results from a percentage of indium in the base layer being greater than 54.5%, that is a lattice constant of the base layer is substantially larger than a lattice constant of the substrate throughout an entire base region.
摘要翻译：一种异质结双极晶体管（HBT），其具有由磷化铟（InP）形成的衬底并且具有形成在衬底上的发射极，基极和集电极层，使得基极层设置在发射极和集电极层之间。集电极层由InGaAs形成，集电极层掺杂n型。由InP形成的发射极层和发射极层双掺杂n型。由砷化铟镓（InGaAs）形成的基层，基层压缩失配，掺杂p型。衬底和基底材料之间的晶格失配大于0.2％。在异质结双极晶体管的x射线摇摆曲线中，对应于基底层的峰与对应于衬底层的峰分开至少-250弧秒。在一个实施例中，这是由于基底层中的铟的百分比大于54.5％，即基底层的晶格常数基本上大于整个基底区域中的衬底的晶格常数。

7. 发明申请

WO2007121274A3 APPLICATION RISK AND CONTROL ASSESSMENT TOOL 审中-公开
公开(公告)号：WO2007121274A3
公开(公告)日：2007-10-25
申请号：PCT/US2007/066472
申请日：2007-04-11
申请人： BANK OF AMERICA CORPORATION , OSBORN, Frank, Davis , FIRESTONE, Jacob , WEAVER, David, H. , MURPHY, Peter
发明人： OSBORN, Frank, Davis , FIRESTONE, Jacob , WEAVER, David, H. , MURPHY, Peter
IPC分类号： G06F11/36
摘要： A tool to assess risks associated with software applications, and controls implemented to mitigate these risks, includes a first software component configured to gather information about the risks and controls, and a second software component configured to display the gathered information. The first software component includes a self-assessment tool which is invoked by a user to enter information reflective of risk levels over a number of risk categories. These risk levels are used to calculate a risk score associated with a particular application. The user also enters information as to whether or not a number of specific control attributes have been implemented, and this information is used to calculate a control score. This process may be repeated for each of several software applications. The second software component allows one to selectively display various subsets, or even the entire population, of the collected information by invoking various combinations of parametric filters on the compiled information.

8. 发明申请

WO2006083744A1 ANCHORING OF A MEDICAL DEVICE COMPONENT ADJACENT A DURA OF THE BRAIN OR SPINAL CORD 审中-公开
标题翻译：医疗器械组件的附着物邻近脑或脊髓的DURA
公开(公告)号：WO2006083744A1
公开(公告)日：2006-08-10
申请号：PCT/US2006/003096
申请日：2006-01-25
申请人： MEDTRONIC, INC. , OSORIO, Ivan
发明人： OSORIO, Ivan
IPC分类号： A61N1/05 , A61N1/372
CPC分类号： A61N1/0531 , A61B5/4094 , A61B5/6864 , A61N1/0539 , A61N1/0553
摘要： A method and implantable medical device system capable of being anchored in a head or spinal cord of a patient. During implant, the dura of the patient is partially removed and the medical device component 202 is placed on one side of the dura. The medical device component 202 contains one or more anchors that mate with one or more nuts placed on the other side of the dura. The medical device component 202 is thereby attached to the dura in a substantially fixed position relative to the head or spinal cord.
摘要翻译：一种能够锚定在患者的头部或脊髓中的方法和可植入的医疗装置系统。在植入期间，患者的硬膜被部分地去除，并且医疗装置部件202被放置在硬脑膜的一侧。医疗器械部件202包含一个或多个锚定件，其与置于硬脑膜另一侧的一个或多个螺母配合。因此，医疗装置部件202相对于头部或脊髓以基本上固定的位置附接到硬脑膜。

9. 发明申请

WO2006050360A1 TECHNIQUES FOR USER-ACTIVATED DATA RETENTION IN AN IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：用于在可移植医疗设备中用户激活数据保持的技术
公开(公告)号：WO2006050360A1
公开(公告)日：2006-05-11
申请号：PCT/US2005/039478
申请日：2005-11-02
申请人： MEDTRONIC, INC. , DREW, Touby, A.
发明人： DREW, Touby, A.
IPC分类号： A61B5/04 , A61B5/00
CPC分类号： A61B5/4094 , A61B5/0006 , A61B5/0031 , A61B5/02055 , A61B5/021 , A61B5/024 , A61B5/031 , A61B5/04001 , A61B5/04012 , A61B5/0402 , A61B5/0476 , A61B5/0816 , A61B5/1118 , A61B5/165 , A61B5/4082 , A61B5/686 , A61B5/7232 , A61B5/7282 , A61N1/36132 , A61N1/36135 , A61N1/36521 , A61N1/36585 , A61N1/3702 , A61N1/37252 , A61N1/37282 , G06F17/30336 , G06F19/00 , G06F19/3418 , G16H10/60 , G16H40/63
摘要： Apparatus for storing data records associated with a medical monitoring event in a data structure [1600]. Upon indication by a patient of a possible manifestation of a neurological event, the implanted device [100] obtains and stores data in the data record in a first data structure [1601] that is age-based. Before an oldest data record is lost, the oldest data record may be stored in a second data structure [1602] that is priority index-based. The priority index may be determined by a severity level and may be further determined by associated factors. The implanted device [100] may organize, off-load, report, and/or display a plurality of data records based on an associated priority index. Additionally, the implanted device [100] may select a subset or composite of physiologic channels from the available physiologic channels based on a selection criterion.
摘要翻译：用于存储与数据结构中的医疗监视事件相关联的数据记录的装置[1600]。在由患者指示神经系统事件的可能表现时，植入装置[100]以基于年龄的第一数据结构[1601]获得并存储在数据记录中的数据。在最旧的数据记录丢失之前，最早的数据记录可以存储在基于优先级索引的第二数据结构[1602]中。优先权索引可以由严重性级别确定，并且可以由相关因素进一步确定。植入装置[100]可以基于相关联的优先级索引来组织，卸载，报告和/或显示多个数据记录。另外，植入装置[100]可以基于选择标准从可用的生理通道中选择生理通道的子集或复合物。

10. 发明申请

WO2004034982A2 CYCLE MODE PROVIDING REDUNDANT BACK-UP TO ENSURE TERMINATION OF TREATMENT THERAPY IN A MEDICAL DEVICE SYSTEM 审中-公开
标题翻译：提供冗余备份的循环模式，以确保医疗设备系统中的治疗终止治疗
公开(公告)号：WO2004034982A2
公开(公告)日：2004-04-29
申请号：PCT/US2003/032572
申请日：2003-10-15
申请人： MEDTRONIC INC. , OSORIO, Ivan , BHAVARAJU, Naresh, C. , CARLSON, David, L. , JENSEN, Randy, M.
发明人： OSORIO, Ivan , BHAVARAJU, Naresh, C. , CARLSON, David, L. , JENSEN, Randy, M.
IPC分类号： A61K
CPC分类号： A61N1/37252 , A61N1/36064 , A61N1/36135 , A61N1/37235
摘要： A medical device system having a redundant back-up mechanism to ensure that treatment therapy is turned off after a given time duration. Once the treatment therapy is initiated, a cycle ON timer is set. If the ON timer expires prior to receiving any instruction to turn off the treatment therapy, the device responsively turns off the treatment therapy, thereby ensuring that the treatment therapy is not delivered beyond that which is desired.
摘要翻译：一种具有冗余备用机制的医疗装置系统，以确保治疗疗法在给定的持续时间之后被关闭。一旦开始治疗，就设置一个循环ON定时器。如果接通定时器在接收任何关闭治疗疗法的指令之前过期，则该设备响应地关闭治疗疗法，从而确保治疗疗法不会超出期望的范围。

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