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1. 发明申请

WO2016057795A1 IMPROVED PEPTIDE INHIBITORS OF SODIUM CHANNELS 审中-公开
标题翻译：改善肽通道的肽抑制剂
公开(公告)号：WO2016057795A1
公开(公告)日：2016-04-14
申请号：PCT/US2015/054693
申请日：2015-10-08
申请人： THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL , SPYRYX BIOSCIENCES, INC.
发明人： TARRAN, Robert , CHRISTENSEN, Dale J.
IPC分类号： A61K38/04 , A61K38/16 , A61P1/00 , A61P11/06 , A61P11/08 , A61P11/12 , C07K14/435
CPC分类号： C07K7/08 , A61K9/0073 , A61K38/00 , C07K5/06026 , C07K7/06 , C07K14/705 , C07K2319/00 , C07K2319/10
摘要： The present invention relates to the ability of specialized non-naturally occurring peptides to bind to sodium channels and inhibit activation of the sodium channels. The invention further relates to methods for regulating of sodium absorption and fluid volume and treating disorders responsive to modulating sodium absorption by modulating the binding of specialized non-naturally occurring peptides to sodium channels.
摘要翻译：本发明涉及专门的非天然存在的肽结合钠通道并抑制钠通道活化的能力。本发明还涉及通过调节专门的非天然存在的肽与钠通道的结合来调节钠吸收和流体体积以及治疗响应于调节钠吸收的病症的方法。

2. 发明申请

WO2015195920A1 THREE-DIMENSIONAL PRINTING METHOD USING INCREASED LIGHT INTENSITY AND APPARATUS THEREFORE 审中-公开
标题翻译：使用增加光强度的三维打印方法及其设备
公开(公告)号：WO2015195920A1
公开(公告)日：2015-12-23
申请号：PCT/US2015/036437
申请日：2015-06-18
申请人： CARBON3D, INC.
发明人： DESIMONE, Joseph M. , PHELPS, Nordstrom Kirk , ERMOSHKIN, Alexander
IPC分类号： B29C67/00 , B33Y10/00 , B33Y30/00 , B33Y50/02
CPC分类号： B29C64/135 , B29C64/129 , B29C64/20 , B29C64/386 , B29K2105/0002 , B29K2105/0058 , B33Y10/00 , B33Y30/00 , B33Y50/02
摘要： A method of forming a three-dimensional object includes: providing a carrier and an optically transparent member having a build surface, the carrier and the build surface defining a build region therebetween; filling the build region with a polymerizable liquid, irradiating the build region with light through the optically transparent member to form a solid polymer from the polymerizable liquid, and advancing said carrier away from said build surface to form said three-dimensional object from said solid polymer. The irradiating step includes projecting focused light at the build region, and the advancing step is carried out at a rate that is dependent on an average light intensity of the focused light. An apparatus to perform the method is also disclosed.
摘要翻译：形成三维物体的方法包括：提供具有构造表面的载体和光学透明构件，所述载体和构建表面在其间限定构建区域; 用可聚合液体填充构建区域，通过光学透明构件用光照射构建区域以从可聚合液体形成固体聚合物，并使所述载体远离所述构建表面，从所述固体聚合物形成所述三维物体。照射步骤包括将聚焦光投射在构建区域，并且前进步骤以取决于聚焦光的平均光强度的速率进行。还公开了一种执行该方法的装置。

3. 发明申请

WO2015195909A1 THREE-DIMENSIONAL PRINTING USING TILED LIGHT ENGINES 审中-公开
标题翻译：使用倾斜光发动机的三维打印
公开(公告)号：WO2015195909A1
公开(公告)日：2015-12-23
申请号：PCT/US2015/036421
申请日：2015-06-18
申请人： CARBON3D, INC.
发明人： DESIMONE, Joseph M. , PHELPS, Nordstrom Kirk , ERMOSHKIN, Alexander
IPC分类号： B29C67/00 , B33Y10/00 , B33Y30/00
CPC分类号： B33Y30/00 , B29C35/0805 , B29C64/129 , B29C64/386 , B29C64/40 , B29C2035/0827 , B29C2035/0833 , B29K2027/18 , B33Y10/00 , B33Y50/02
摘要： A method of forming a three-dimensional object includes: providing a carrier and an optically transparent member having a build surface, the carrier and the build surface defining a build region therebetween, filling the build region with a polymerizable liquid, irradiating the build region with light through the optically transparent member to form a solid polymer from the polymerizable liquid, and advancing the carrier away from the build surface to form the three-dimensional object from the solid polymer. The irradiating step is carried out with a plurality of tiled images projected into the build region, and each tiled image includes an array of projected pixels. An apparatus to perform the method is also discloses.
摘要翻译：形成三维物体的方法包括：提供具有构建表面的载体和光学透明构件，载体和构建表面在其间限定构建区域，用可聚合液体填充构建区域，用构建区域照射构建区域，通过光学透明构件发光，从可聚合液体形成固体聚合物，并使载体远离构建表面，从固体聚合物形成三维物体。照射步骤用投影到构建区域中的多个平铺图像进行，并且每个平铺图像包括投影像素的阵列。还公开了一种执行该方法的装置。

4. 发明申请

WO2015121794A1 SYSTEMS AND METHODS FOR APPLICATION OF COATINGS INCLUDING THIXOTROPIC AGENTS ONTO OPTICAL ELEMENTS, AND OPTICAL ELEMENTS HAVING COATINGS INCLUDING THIXOTROPIC AGENTS 审中-公开
标题翻译：将包含二十四烷酸衍生物的涂料应用于光学元件的系统和方法以及具有包括二十四烷基偶氮染料的涂料的光学元件
公开(公告)号：WO2015121794A1
公开(公告)日：2015-08-20
申请号：PCT/IB2015/050989
申请日：2015-02-10
申请人： CREE, INC.
发明人： ANDREWS, Peter S. , VU, Jack T.
IPC分类号： B05D1/02
CPC分类号： H01L33/507 , H01L33/0095 , H01L2224/48091 , H01L2224/8592 , H01L2933/0041 , H01L2924/00014
摘要： A method of forming an optical device includes providing an optical element, providing a luminescent suspension including a liquid encapsulant material, phosphor particles, a solvent and a thixotropic agent, atomizing the luminescent suspension, and spraying the atomized luminescent suspension onto the optical element using a flow of pressurized gas. A light emitting structure includes an optical element configured to emit light upon energization thereof, and a thin phosphor layer including a thixotropic agent on the optical element.
摘要翻译：一种形成光学器件的方法包括提供光学元件，提供包括液体密封剂材料，荧光体颗粒，溶剂和触变剂的发光悬浮液，雾化发光悬浮液，以及将雾化的发光悬浮液喷雾到光学元件上，使用加压气流。发光结构包括被配置为在通电时发光的光学元件和在光学元件上包括触变剂的薄的荧光体层。

5. 发明申请

WO2015085050A1 LEDS CONFIGURED FOR TARGETED SPECTRAL POWER DISBUTION 审中-公开
标题翻译： LED被配置用于特定的光谱功率分布
公开(公告)号：WO2015085050A1
公开(公告)日：2015-06-11
申请号：PCT/US2014/068534
申请日：2014-12-04
申请人： CREE, INC.
发明人： VAN DE VEN, Antony P. , REYNOLDS, Matthew C.
IPC分类号： H05B37/02 , H05B33/08
CPC分类号： H05B33/0866 , H05B33/0803
摘要： A dimmable solid state lighting apparatus can include a plurality of light emitting diode (LED) segments including a first LED segment that can have a targeted spectral power distribution for light emitted from the apparatus that is different than spectral power distributions for other LED segments included in the plurality of LED segments. An LED segment selection circuit can be configured to selectively control current through the plurality of LED segments to shift the light emitted by the apparatus to the targeted spectral power distribution responsive to dimming input.
摘要翻译：可调光固态照明装置可以包括多个发光二极管（LED）段，其包括第一LED段，该第一LED段可以具有针对从装置发射的光的目标光谱功率分布，其不同于包括在其中的其它LED段的光谱功率分布多个LED段。 LED段选择电路可以被配置为选择性地控制通过多个LED段的电流，以响应于调光输入将由装置发射的光移动到目标光谱功率分布。

6. 发明申请

WO2014204834A1 COAXIAL CABLE AND CONNECTOR WITH CAPACITIVE COUPLING 审中-公开
标题翻译：同轴电缆和连接器与电容耦合
公开(公告)号：WO2014204834A1
公开(公告)日：2014-12-24
申请号：PCT/US2014/042474
申请日：2014-06-16
申请人： ANDREW LLC
发明人： VACCARO, Ronald A. , SMENTEK, David
IPC分类号： H01R24/38 , H01R9/05
CPC分类号： H01R24/42 , H01R13/405 , H01R2103/00
摘要： A coaxial cable-connector assembly includes a coaxial cable and a coaxial cable connector. The coaxial cable includes: a central conductor having a connector end; a dielectric layer that overlies the central conductor; and an outer conductor that overlies the dielectric layer having a connector end. The coaxial connector includes: a central conductor extension configured to mate with a mating connector at one end; a first insulative layer interposed between an opposed second end of the central conductor extension and the connector end of the central conductor; an outer conductor extension configured to mate with a mating connector at one end; and a second insulative layer interposed between an opposed second end of the outer conductor extension and the connector end of the outer conductor. This configuration can reduce and/or avoid PIM within the connection of two coaxial connectors.
摘要翻译：同轴电缆连接器组件包括同轴电缆和同轴电缆连接器。同轴电缆包括：具有连接器端的中心导体; 覆盖中心导体的介电层; 以及覆盖在具有连接器端的电介质层的外部导体。同轴连接器包括：中心导体延伸部，其构造成在一端与配合连接器配合; 插入在所述中心导体延伸部的相对的第二端和所述中心导体的连接器端之间的第一绝缘层; 外部导体延伸部，其构造成在一端与匹配连接器配合; 以及插入在外导体延伸部的相对的第二端和外导体的连接器端之间的第二绝缘层。该配置可以在两个同轴连接器的连接内减少和/或避免PIM。

7. 发明申请

WO2014113806A1 MOBILE ROBOT PROVIDING ENVIRONMENTAL MAPPING FOR HOUSEHOLD ENVIRONMENTAL CONTROL 审中-公开
标题翻译：移动机器人为环境调控提供环境影像
公开(公告)号：WO2014113806A1
公开(公告)日：2014-07-24
申请号：PCT/US2014/012368
申请日：2014-01-21
申请人： IROBOT CORPORATION
发明人： ANGLE, Colin , SNELLING, David , O'DEA, Melissa , FARLOW, Timothy, S. , DUFFLEY, Samuel , MAMMEM, Jeffrey, W. , HALLORAN, Michael, J.
IPC分类号： B25J9/00 , H04L12/12 , A47L11/24
CPC分类号： G05D1/0016 , A47L9/2857 , A47L11/4011 , A47L2201/00 , G05D2201/0203
摘要： A mobile robot includes a processor connected to a memory and a wireless network circuit, for executing routines stored in the memory and commands generated by the routines and received via the wireless network circuit. The processor drives the mobile robot to a multiplicity of accessible two dimensional locations within a household, and commands an end effector, including at least one motorized actuator, to perform mechanical work in the household. A plurality of routines include a first routine which monitors a wireless local network and detects a presence of a network entity on the wireless local network, a second routine which receives a signal from a sensor detecting an action state of one of the network entities, the action state changeable between waiting and active, and a third routine which commands the end effector to change state of performing mechanical work based on the presence and on the action state.
摘要翻译：移动机器人包括连接到存储器和无线网络电路的处理器，用于执行存储在存储器中的例程以及由例程产生并通过无线网络电路接收的命令。处理器将移动机器人驱动到家庭内的多个可访问的二维位置，并命令包括至少一个机动执行器的末端执行器在家庭中执行机械作业。多个例程包括监视无线本地网络并检测无线本地网络上网络实体的存在的第一例程;接收来自检测网络实体之一的动作状态的传感器的信号的第二例程，动作状态在等待和活动之间可变，以及第三程序，其命令末端执行器基于存在和动作状态改变执行机械作业的状态。

8. 发明申请

WO2014057329A3 BEAMFORMING FOR INCREASING CELL EDGE CAPACITY IN A HETEROGENEOUS NETWORK 审中-公开
公开(公告)号：WO2014057329A3
公开(公告)日：2014-04-17
申请号：PCT/IB2013/002194
申请日：2013-10-03
申请人： TELEFONAKTIEBOLAGET L M ERICSON (PUBL)
发明人： AHMAD, Talha , BOUDREAU, Gary, David
IPC分类号： H04B7/02 , H04B7/06
摘要： Methods of communicating with a selected user equipment terminal (UE) in a first cell served by a base station and a remote radio head include forming a list of non-targeted UEs including other UEs in the first cell and cell edge UEs in a neighboring cell that borders the first cell that are located near a border of the first cell and the neighboring cell, generating a list of candidate precoding matrices that can be used to communicate with the selected UE from the base station and/or from the remote radio head, generating a list of available precoding matrices by discarding from the list of candidate precoding matrices those precoding matrices that may cause interference to at least one non-targeted UE, selecting a precoding matrix from the list of available precoding matrices, and communicating with the selected UE using the selected precoding matrix.

9. 发明申请

WO2014043004A1 LIGHT USING ENERGY STORAGE WITH SEGMENT CONTROL 审中-公开
标题翻译：使用分段控制的能源储存光
公开(公告)号：WO2014043004A1
公开(公告)日：2014-03-20
申请号：PCT/US2013/058682
申请日：2013-09-09
申请人： CREE, INC.
发明人： ZHANG, Jun , NI, Liqin
IPC分类号： H05B37/00 , H05B37/02 , H05B41/36
CPC分类号： H05B33/0824 , H05B33/083
摘要： A lighting apparatus includes a rectifier circuit configured to be coupled to an AC source and to produce a rectified voltage from an AC voltage and a string including at least two serially-connected LED segments and coupled to the rectifier circuit. A segment control circuit is configured to selectively bypass at least one segment of the string responsive to the rectified voltage. An energy storage circuit is coupled to the rectifier circuit and controls current flow between at least one energy storage device and the string. A control circuit controls the segment control circuit and the energy storage circuit. The segment control circuit may support a current from the rectifier circuit through all of the segments in the string circuit at a peak of the rectified voltage and the energy storage circuit may charge the at least one energy storage device to a voltage near the peak of the rectified voltage.
摘要翻译：照明装置包括整流电路，其被配置为耦合到AC源并且从AC电压和包括至少两个串联连接的LED段的串产生整流电压并且耦合到整流器电路。段控制电路被配置为响应于整流电压选择性地旁路串的至少一个段。能量存储电路耦合到整流器电路并且控制至少一个能量存储装置与串之间的电流。控制电路控制分段控制电路和能量存储电路。分段控制电路可以支持来自整流电路的电流通过整流电压的峰值处的串电路中的所有段，并且能量存储电路可以将至少一个能量存储装置充电到接近峰值的电压整流电压。

10. 发明申请

WO2013192396A1 SAMPLE COLLECTION AND TRANSFER ASSEMBLY AND RELATED METHODS 审中-公开
标题翻译：样品收集和转移装配及相关方法
公开(公告)号：WO2013192396A1
公开(公告)日：2013-12-27
申请号：PCT/US2013/046760
申请日：2013-06-20
申请人： ADVANCED ANIMAL DIAGNOSTICS, INC.
发明人： CALDERWOOD, David A. , DRACH, Joy Parr , PAUL, Chris , RODRIGUEZ, Rodolfo R. , HOCKETT, Mitch , MARCUSON, Randall , MIGGELS, Stephen G.
IPC分类号： A01J5/013 , G01N1/28 , B01L3/00
CPC分类号： A61B10/0045 , A01J5/045 , A61B90/90 , A61B90/94 , A61B90/96 , A61B90/98 , B01L3/502 , B01L2300/046 , B01L2300/047 , B01L2300/0663 , B01L2400/0406 , B01L2400/0457 , G01N1/10 , G01N1/2813 , G01N33/04
摘要： A collection device includes a base housing member having at least one chamber. A cover housing member has at least one aperture therein, and the cover housing member is configured to cover the base housing member such that the at least one aperture is positioned in fluid communication with the at least one chamber. The cover housing member includes a cartridge holding interface configured to releasably engage with a cartridge that is configured to cover and receive a fluid from the at least one chamber via the at least one aperture.
摘要翻译：收集装置包括具有至少一个室的基部壳体构件。盖壳体构件在其中具有至少一个孔，并且盖壳体构件构造成覆盖基座壳体构件，使得至少一个孔定位成与至少一个腔室流体连通。盖壳体构件包括盒保持接口，该盒保持接口构造成与盒被可释放地接合，该盒构造成经由至少一个孔覆盖和接收来自至少一个室的流体。

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