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    • 2. 发明申请
    • ILLUMINATED LOW-VISION SPECTACLES
    • 照明低视角
    • WO2007058706A2
    • 2007-05-24
    • PCT/US2006/037669
    • 2006-09-28
    • VANDERBILT UNIVERSITYSONSINO, Jeffrey
    • SONSINO, Jeffrey
    • G02C7/08
    • G02C7/14G02C11/04
    • Lighted reading glasses or spectacles for individuals with low vision, including macular degeneration, that provide enhanced viewing of text comprising: a frame for supporting lenses having an oculus dexter side and an oculus sinister side, at least one oculus dexter lens supported by the frame on the oculus dexter side, and at least one oculus sinister lens supported by the frame on the oculus sinister side, the lenses being adjacent to and laterally spaced from each other and providing a predetermined field of view for a user, each of said lenses having an induced prism and a lens power sufficient to enhance the reading of text in the predetermined field view of the individual with low vision; preferably having an induced prism of between 4 and 22 PD and a lens power of between +4.00 and +20.00 diopters, and a pair of lights, each having a predetermined light strength and mounted adjacent the outer portions of the lenses and oriented to project light to provide a predetermined overlapping lighted area in the predetermined field of view.
    • 对于具有低视力(包括黄斑变性)的个体的点亮的眼镜或眼镜,其提供增强的文本观看,其包括:用于支撑具有触眼侧和眼部阴影侧的透镜的框架,由框架支撑的至少一个触觉透镜 所述透镜侧和由所述镜框支撑在所述眼部阴极侧上的至少一个眼部阴影透镜,所述透镜彼此相邻并且横向间隔开,并且为使用者提供预定视场,每个所述透镜具有 诱导棱镜和透镜功率足以增强具有低视力的个人的预定视场中的文本阅读; 优选具有介于4和22PD之间的诱导棱镜和屈光度在+4.00和+20.00之间的透镜光焦度,以及一对具有预定光强度的光,并且邻近透镜的外部部分安置并定向成投影光 以在预定视野中提供预定的重叠点亮区域。
    • 7. 发明申请
    • AXMI281 TOXIN GENE AND METHODS FOR ITS USE
    • AXMI281毒素基因及其使用方法
    • WO2015038262A2
    • 2015-03-19
    • PCT/US2014/050316
    • 2014-08-08
    • ATHENIX CORP.
    • THAYER, RebeccaSAMPSON, Kimberly, S.LEHTINEN, DuanePETERS, Cheryl
    • C07K14/325
    • C12N15/8286A01N63/02C07K14/325Y02A40/162
    • Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a toxin polypeptide are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated toxin nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed, and antibodies specifically binding to those amino acid sequences. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:2-5, or the nucleotide sequence set forth in SEQ ID NO: 1, as well as variants and fragments thereof.
    • 提供了赋予细菌,植物,植物细胞,组织和种子杀虫活性的组合物和方法。 提供了包含毒素多肽的编码序列的组合物。 编码序列可用于DNA构建体或表达盒中用于在植物和细菌中转化和表达。 组合物还包含转化的细菌,植物,植物细胞,组织和种子。 具体而言,提供了分离的毒素核酸分子。 此外,还包括对应于多核苷酸的氨基酸序列,以及与那些氨基酸序列特异性结合的抗体。 特别地,本发明提供了分离的核酸分子,其包含编码SEQ ID NO:2-5所示的氨基酸序列或SEQ ID NO:1所示的核苷酸序列的核苷酸序列,以及其变体和片段