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1. 发明申请

WO2014041323A8 POLYMERS FOR CONTACT LENSES 审中-公开
公开(公告)号：WO2014041323A8
公开(公告)日：2014-03-20
申请号：PCT/GB2013/000379
申请日：2013-09-10
申请人： OCUTEC LIMITED
发明人： RASHID, Abdul , FRASER, John , HONEYMAN, Gordon , MOHAMMED, Mussarrat
IPC分类号： G02B1/04 , C08G18/48 , C08G18/61 , C08G18/66
摘要： There is provided a polyurethane xerogel prepared from a mixture comprising: (a) at least one isocyanate, (b) at least one silicone containing compound of formula J: wherein at least one group represents a hydrocarbyl group and p represents an integer of from 1 to 40, or at least one R 2 group represents a hydrocarbyl group and q represents an integer of from 1 to 40; and at least one R 3 group represents a hydrocarbyl group and w represents an integer of from 1 to 40, or at least one R 4 group represents a hydrocarbyl group and y represents an integer of from 1 to 40; (c) optionally one or more additional components; wherein the isocyanate and silicone containing compound are reacted under substantially anhydrous conditions. There is also provided a contact lens formed from the polyurethane xerogel.

2. 发明申请

WO2010023557A3 HEURISTIC METHOD OF CODE ANALYSIS 审中-公开
公开(公告)号：WO2010023557A3
公开(公告)日：2010-03-04
申请号：PCT/IB2009/006957
申请日：2009-08-28
申请人： AVG TECHNOLOGIES CZ, S.R.O. , BRIETENBACHER, Zdenek
发明人： BRIETENBACHER, Zdenek
IPC分类号： G06F21/00
摘要： A method of detecting malware at a computing device. The method includes examining a software program comprising a sequence of program instructions, determining whether each instruction in the sequence meets any of a group of suspicion criteria, assigning a instruction-level score to each instruction that meets any of the suspicion criteria, summing the instruction- level scores for each instruction to yield a program-level score, determining whether the program-level score exceeds a threshold, and, if the program-level score exceeds a threshold, developing a report indicating a malware detection result.

3. 发明申请

WO2014080162A1 VIP AND AN ALPHA-ADRENERGIC BLOCKER FOR USE IN THE DIAGNOSIS OF ERECTILE DYSFUNCTION AND VASCULAR ISCHAEMIA 审中-公开
标题翻译： VIP和ALPHA-ADRENERGIC阻塞器用于诊断溃疡性功能障碍和血管异位症
公开(公告)号：WO2014080162A1
公开(公告)日：2014-05-30
申请号：PCT/GB2013/000509
申请日：2013-11-21
申请人： MENS HEALTH LTD
发明人： WYLLIE, Mike
IPC分类号： A61K38/22 , A61K45/06 , A61P9/10
CPC分类号： A61K38/2278 , A61K31/417 , A61K45/06 , A61K2300/00
摘要： The present invention provides a method of providing an objective, repeatable measure of the severity of an erectile dysfunction condition comprising: a) the administration in a therapeutically effective amount of a physiological mediator of penile erection, generally a vasoactive intestinal peptide (VIP) and a therapeutically effective amount of an alpha-adrenergic blocker; b) measuring the erectile response; c) grading the severity of the ED condition through the erectile response measurements. There is also provided a method of diagnosing a patient suffering from vascular ischaemia comprising: • identifying an area of the body (typically a limb) exhibiting symptoms of vascular ischaemia; • administering a therapeutically effective amount of a vasoactive intestinal peptide (VIP) and a therapeutically effective amount of an alpha-adrenergic blocker; wherein if the symptoms of vascular ischaemia are alleviated, eliminated or relieved within a predetermined period from administration, the patient is likely to be suffering from vascular ischaemia. The VIP is generally included in a composition having a pH of from around 6 to around 9.
摘要翻译：本发明提供了提供勃起功能障碍病症严重程度的客观可重复测量的方法，包括：a）以治疗有效量的阴茎勃起生理介质（通常为血管活性肠肽（VIP））和治疗有效量的α-肾上腺素能阻滞剂; b）测量勃起反应; c）通过勃起反应测量法评估ED病情的严重程度。还提供了一种诊断患有血管缺血的患者的方法，包括：•鉴定表现血管缺血症状的身体区域（通常为肢体）; •施用治疗有效量的血管活性肠肽（VIP）和治疗有效量的α-肾上腺素能阻滞剂; 其中如果血管局部缺血的症状在给药的预定时间内缓解，消除或缓解，则患者可能患有血管缺血。 VIP通常包括在pH为约6至约9的组合物中。

4. 发明申请

WO2010112848A3 INHIBITION OF BIOFILM ORGANISMS 审中-公开
公开(公告)号：WO2010112848A3
公开(公告)日：2010-10-07
申请号：PCT/GB2010/000631
申请日：2010-03-31
申请人： NOVABIOTICS LIMITED , O'NEIL, Deborah , MERCER, Derry , CHARRIER, Cedric
发明人： O'NEIL, Deborah , MERCER, Derry , CHARRIER, Cedric
IPC分类号： A61K31/145 , A61K38/17 , A61K38/08 , C07K14/47 , A61L29/08 , A61P31/04
摘要： The present invention relates to a product comprising at least two antibiofilm agents wherein at least one of the antibiofilm agents is an antimicrobial peptide. The second antibiofilm agent is generally a dispersant or an anti-adhesive agent. There is also provided the use of the product in the treatment of a microbial infection.

5. 发明申请

WO2014080161A1 VIP AND AN ALPHA-ADRENERGIC BLOCKER FOR USE IN THE TREATMENT OF ERECTILE DYSFUNCTION POST RADICAL PROSTATECTOMY 审中-公开
标题翻译： VIP和一个ALPHA-ADRENERGIC阻塞器用于治疗放射性前列腺切除术后的功能障碍
公开(公告)号：WO2014080161A1
公开(公告)日：2014-05-30
申请号：PCT/GB2013/000508
申请日：2013-11-21
申请人： MENS HEALTH LTD
发明人： WILLIE, Mike
IPC分类号： A61K38/22 , A61K45/06 , A61P9/10
CPC分类号： A61K38/2278 , A61K31/417 , A61K45/06 , A61K2300/00
摘要： The present invention provides a method of treating a patient suffering from post radical prostatectomy erectile dysfunction (ED RP), in particular iatrogenic reversible erectile dysfunction post radical prostatectomy, comprising the administration of a therapeutically effective amount of a vasoactive intestinal peptide (VDP) and a therapeutically effective amount of an alpha-adrencrgic blocker. Generally the VIP is in the form of a composition having a pH of from around 6 to around 9.
摘要翻译：本发明提供一种治疗患有根治性前列腺切除术勃起功能障碍（ED RP）的患者，特别是根治性前列腺切除术后的医源性可逆性勃起功能障碍的患者的方法，其包括施用治疗有效量的血管活性肠肽（VDP）和治疗有效量的α-肾上腺阻滞剂。通常，VIP是pH为约6至约9的组合物的形式。

6. 发明申请

WO2011077087A2 METHOD OF ESTABLISHING A FUNGAL NAIL INFECTION 审中-公开
标题翻译：建立真菌感染的方法
公开(公告)号：WO2011077087A2
公开(公告)日：2011-06-30
申请号：PCT/GB2010/002313
申请日：2010-12-20
申请人： NOVABIOTICS LIMITED , O'NEIL, Deborah , MERCER, Derry , STEWART, Colin
发明人： O'NEIL, Deborah , MERCER, Derry , STEWART, Colin
IPC分类号： C12Q1/18
CPC分类号： C12Q1/18 , C12Q1/24 , G01N33/5088
摘要： The present invention provides a method of infecting a nail fragment with a fungus, to form an infected nail fragment comprising at least 1 x 102 fungal colony forming units (cfu) per cm2 of the infected surface(s). There is also provided a method of assessing the efficacy of potential therapeutic compounds in the treatment or prevention of a fungal nail infection. The fungal nail infection may be a dermatophyte, a non-dermatophyte mould or a pathogen.
摘要翻译：本发明提供了用真菌感染指甲片段以形成感染的指甲片段的方法，所述感染的指甲片段包含每cm 2感染表面至少1×10 2个真菌菌落形成单位（cfu））。还提供了评估潜在治疗性化合物在治疗或预防真菌性指甲感染中的功效的方法。真菌指甲感染可以是皮肤真菌，非皮肤真菌霉菌或病原体。

7. 发明申请

WO2014057233A3 SCREENING METHOD AND APPARATUS 审中-公开
公开(公告)号：WO2014057233A3
公开(公告)日：2014-04-17
申请号：PCT/GB2013/000420
申请日：2013-10-08
申请人： LANCASTER UNIVERSITY BUSINESS ENTERPRISES LTD
发明人： FORDE, Brian Gordon
IPC分类号： A01G9/10 , G06K9/00 , G06T7/00
摘要： According to the present invention there is provided an organism growth array device suitable for automated phenotypic analysis of either plants or microorganisms under aseptic conditions and comprising: a plurality of receptacles, each receptacle having a housing comprising first and second open ends and one or more longitudinal sides extending from the first open end to the second open end, wherein at least one of the longitudinal sides is flat, and wherein a portion of each receptacle is fused to the neighbouring receptacle(s) along at least 10% of its length along the longitudinal axis of the receptacle; growth medium housed within the housing extending from a first surface of the growth medium, disposed longitudinally towards the first open end of the receptacle to a second surface of the growth medium disposed towards the second open end of the receptacle, wherein generally, in use, the first surface of the growth medium is disposed above the second surface of the growth medium; wherein the open ends of each receptacle are individually accessible, preferably for the addition of different compositions; and wherein the growth medium of each receptacle is visible, and imagable across the lateral axis of the receptacle and along the longitudinal axis of the receptacle from the first surface to the second surface, and in use the growth of the organism within or into the growth medium is visible and imagable across the lateral axis of the receptacle and along the longitudinal length of the growth medium. There is also provided a method of imaging and/or analysing the development of one or more organisms.

8. 发明申请

WO2013186513A2 APPARATUS 审中-公开
标题翻译：仪器
公开(公告)号：WO2013186513A2
公开(公告)日：2013-12-19
申请号：PCT/GB2013/000257
申请日：2013-06-11
申请人： SOFTCELL MEDICALS LIMITED
发明人： MCINTOSH, Kirsty
IPC分类号： A61B5/145
CPC分类号： A61B5/14539 , A61B5/14503 , A61B5/1473 , A61B5/1495 , A61B5/4519 , A61B5/4848 , A61B5/7275 , A61B5/7282 , A61B5/742 , A61B5/746 , A61B2560/0228 , A61B2560/0276 , A61B2560/028 , A61B2562/242
摘要： The present invention relates to a pH sensor adapted to be inserted into all soft tissues, such as muscle, fat or other organs e.g. heart, lung, kidney, liver, pancreas, renal gland etc., comprising one or more of: a) means to provide sensor calibration performance information; b) a sensor dislodgement alert, providing an indication to the user if the pH reading falls outside a predetermined range; c) an alert to indicate that the sensor has exceeded its usage period; and d) an alert to indicate that the sensor had exceeded its shelf life. There is also provided a method of assessing the efficacy of a treatment regime comprising the steps of determining any change in the pH of the soft tissue during treatment, where any change in the pH towards the preferred range for the tissue type is indicative of an effective treatment regime and any change in the pH away from the preferred range for the tissue type is indicative of a worsening in the condition of the tissue, and thus an ineffective treatment regime.
摘要翻译：本发明涉及适于插入所有软组织如肌肉，脂肪或其他器官的pH传感器，心脏，肺，肾，肝，胰腺，肾腺等，包括以下一个或多个：a）提供传感器校准性能信息的手段; b）传感器移动警报，如果pH读数落在预定范围之外，则向用户提供指示; c）警报以指示传感器已超出其使用期限; 和d）警报以指示传感器已超过其保质期。还提供了一种评估治疗方案的功效的方法，其包括以下步骤：在治疗期间确定软组织的pH值的任何变化，其中对于组织类型，pH朝向优选范围的任何变化指示有效治疗方案和离开组织类型的优选范围的pH的任何变化表明组织状况恶化，从而导致无效的治疗方案。

9. 发明申请

WO2010023556A2 CROSS SITE, CROSS DOMAIN SESSION SHARING WITHOUT DATABASE REPLICATION 审中-公开
标题翻译：交叉站点，跨域会话共享，无数据库复制
公开(公告)号：WO2010023556A2
公开(公告)日：2010-03-04
申请号：PCT/IB2009/006954
申请日：2009-08-28
申请人： AVG TECHNOLOGIES CZ, S.R.O. , SEDLACEK, Vladimir
发明人： SEDLACEK, Vladimir
CPC分类号： H04L67/1008 , H04L67/1002 , H04L67/101 , H04L67/1014 , H04L67/1017 , H04L67/1027 , H04L67/1029 , H04L67/14
摘要： A method of providing access to data via a public communications network includes the receiving a first data session request having a storage group mark, the storage group mark defining a server storage group, a load balancer route the request to a first server that processes request and any related session information, storing any altered first session data in a data storage. The load balancer receives a second request, wherein the second request also has the same storage group mark. The load balance selects a second server to respond to the second request As before, the second server processes the second request and the altered first session data loaded from the data storage. After processing, the second server stores any altered second session data in the stored data on the first server as well as the second server and returns the altered second session data.
摘要翻译：提供通过公共通信网络访问数据的方法包括接收具有存储组标记的第一数据会话请求，定义服务器存储组的存储组标记，负载平衡器将请求路由到处理请求的第一服务器，任何相关会话信息，将任何改变的第一会话数据存储在数据存储器中。负载平衡器接收第二请求，其中第二请求也具有相同的存储组标记。负载平衡选择第二服务器来响应第二请求如前所述，第二服务器处理从数据存储器加载的第二请求和改变的第一会话数据。在处理之后，第二服务器将存储的数据中的任何改变的第二会话数据存储在第一服务器以及第二服务器上，并返回改变的第二会话数据。

10. 发明公开

EP4344894A2 METHODS FOR PREPARING COMPOSITIONS COMPRISING CARBON BLACK 审中-实审
公开(公告)号：EP4344894A2
公开(公告)日：2024-04-03
申请号：EP24157851.7
申请日：2017-11-30
申请人： Landa Labs (2012) Ltd.
发明人： LANDA, Benzion , ABRAMOVICH, Sagi , LION, Amir , HAVIV, Amit
IPC分类号： B41N10/00
摘要： There are disclosed methods for producing curable elastomeric compositions comprising carbon black particles, as well as their corresponding cured products. Such compositions, once cured, can be used for the preparation of numerous articles of wide industrial applicability.

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