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    • 4. 发明申请
    • DIACYLGLYCEROL RICH FATS, OILS AND FUNCTIONAL FOODS
    • DIACYLGLYCEROL富含脂肪,油和功能食品
    • WO2010019598A1
    • 2010-02-18
    • PCT/US2009/053442
    • 2009-08-11
    • ABUNDA, INC.KISHORE, Ganesh
    • KISHORE, Ganesh
    • A23D9/007A23L1/29
    • A23D9/013A21D2/16A21D2/165A23C9/1315A23C15/126A23C19/093A23L7/126A23L25/10A23L33/11A23L33/115A23L33/30A61K31/23A61K31/231A61K45/06A61K2300/00
    • Disclosed is a fat or oil useful for cooking applications which includes from 10 to 90 % DAG, and comprises at least 15% solids at room temperature; in particular embodiments, the fat or oil is derived from palm oil, palm kernel oil, coconut oil, sunflower oil, soybean oil, corn oil, rapeseed oil, grape seed oil, rice bran oil, sesame oil, and peanut oil, or any combination thereof, and exhibits health benefits including lowered serum LDL, raised serum HDL, lowered total serum cholesterol, reduced risk of metabolic syndrome, reduced risk of diabetes mellitus, enhanced fetal health, enhanced insulin sensitivity, reduced risk of hypertension, and enhanced resistance to obesity per unit of consumption. Food compositions and methods of health enhancement utilising the fats and oils of the invention are also disclosed.
    • 公开了一种用于烹饪应用的脂肪或油,其包括10至90%的DAG,并且在室温下包含至少15%的固体; 在具体实施方案中,脂肪或油衍生自棕榈油,棕榈仁油,椰子油,向日葵油,大豆油,玉米油,菜籽油,葡萄籽油,米糠油,芝麻油和花生油,或任何 并且具有健康益处,包括降低的血清LDL,升高的血清HDL,降低的总血清胆固醇,降低的代谢综合征的风险,降低的糖尿病风险,增强的胎儿健康,增强的胰岛素敏感性,降低的高血压风险以及增强的抗性 单位消费的肥胖。 还公开了利用本发明的脂肪和油的健康增强的食物组合物和方法。
    • 10. 发明申请
    • CHROMATOGRAPHY OF METAL COMPLEXES
    • 金属复合物的色谱
    • WO2002071054A1
    • 2002-09-12
    • PCT/US2002/006521
    • 2002-03-04
    • METAPHORE PHARMACEUTICALS, INC.SLOMCZYNSKA, Urszula, J.TRAWICK, Bobby, N.RILEY, Denis, P.NAIK, Arati
    • SLOMCZYNSKA, Urszula, J.TRAWICK, Bobby, N.RILEY, Denis, P.NAIK, Arati
    • G01N30/02
    • G01N30/34B01D15/325B01D15/3833B01D15/426G01N30/02G01N2030/884G01N2030/8877B01D2015/3838
    • A high performance liquid chromatography method to routinely and reproducibly detect and quantitate metal complexes. The method comprises loading a solution containing metal complexes onto a column, eluting the metal complex from the column with a mobile phase, the mobile phase comprising an excess of a salt of a coordinating anion in a solvent system, and detecting the metal complex with a detector. Eluting the complex from the column with the mobile phase generates a metal complex in which the coordinating anion (which is a competent ligand) out-competes all other potential ligands present for the available coordination sites on the metal. The metal complexes used in the method of the invention can be different metal complexes, or they can be stereoisomers of the same metal complexes. The high performance liquid chromatography method of the present invention is suitable for the separation of diastereomers of the same metal complexes. Also provided is a chiral high performance liquid chromatography method to separate enantiomers of metal complexes. In this chiral high performance liquid chromatography method a chiral column is employed to achieve the separation of the enantiomers of metal complexes.
    • 高效液相色谱法常规和可重复地检测和定量金属络合物。 该方法包括将含有金属络合物的溶液加载到柱上,用流动相从柱中洗脱金属络合物,流动相在溶剂体系中包含过量的配位阴离子盐,并用金属络合物 探测器。 用流动相从柱中洗脱复合物产生金属络合物,其中配位阴离子(其是有效配体)与金属上可用的配位点存在的所有其它潜在配体竞争。 用于本发明方法的金属络合物可以是不同的金属络合物,或它们可以是相同金属络合物的立体异构体。 本发明的高效液相色谱法适用于分离相同金属络合物的非对映异构体。 还提供了用于分离金属络合物的对映异构体的手性高效液相色谱法。 在这种手性高效液相色谱法中,使用手性柱来实现金属络合物的对映异构体的分离。