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2. 发明专利

JP2020511156A 白扁豆抽出物を有効成分として含有する、二日酔いの解消及びアルコール性胃腸疾患の予防、改善または治療のための組成物审中-公开
公开(公告)号：JP2020511156A
公开(公告)日：2020-04-16
申请号：JP2019554458
申请日：2017-12-14
申请人：コリアインスティテュートオフオリエンタルメディスン , KOREA INSTITUTE OF ORIENTAL MEDICINE
发明人：ソン、クァンフン , キム、ユンヒ
IPC分类号： A61K36/48 , A61K9/10 , A61K9/107 , A61K9/12 , A61K9/14 , A61K9/20 , A61K9/08 , A61K9/48 , A61P1/00 , A23L2/52 , A23L29/30 , A23L33/105
摘要：本発明は、白扁豆抽出物を有効成分として含有する、二日酔いの解消及びアルコール性胃腸疾患の予防、改善または治療のための組成物に関し、アルコール摂取により損傷を受けた胃腸壁を回復させる効果があり、血液中のアルコール及びアセトアルデヒドの含有量を減少させるのみならず、血液中のアルデヒド脱水素酵素の活性を増加させることができる。したがって、本発明の白扁豆抽出物は、アルコールによる二日酔いの解消及び胃腸疾患を予防、改善または治療することができる健康機能食品または医薬品として活用可能である。【選択図】図3

3. 发明申请

WO2015064975A1 COMPOSITIONS COMPRISING A VIOLA HERBA EXTRACT, OR AN EXTRACT OF VIOLA HERBA, PERSICAE SEMEN, CINNAMOMI RAMULUS, AND GLYCYRRHIZA SPP. FOR THE PREVENTION OR TREATMENT OF LIPID-RELATED CARDIOVASCULAR DISEASES AND OBESITY 审中-公开
标题翻译：组合物包含维拉草提取物，或提取薇草，白芍，IN I RAM RAM和。A A A。。用于预防或治疗与脂质相关的心血管疾病和肥胖
公开(公告)号：WO2015064975A1
公开(公告)日：2015-05-07
申请号：PCT/KR2014/010110
申请日：2014-10-27
申请人： KOREA INSTITUTE OF ORIENTAL MEDICINE
发明人： SUNG, Yoon Young , KIM, Ho Kyoung , KIM, Dong Seon , CHOI, Go Ya
IPC分类号： A61K36/86 , A61K36/736 , A61K36/54 , A61K36/484
CPC分类号： A61K36/484 , A61K36/54 , A61K36/736 , A61K36/86 , A61K2300/00
摘要： The present invention relates to a pharmaceutical or a food additive composition comprising a Viola Herba extract, or an extract of Viola Herba, Persicae Semen, Cinnamomi Ramulus, and Glycyrrhiza spp. for the prevention or treatment of lipid-related cardiovascular diseases or obesity, and a method for the treatment of lipid-related cardiovascular diseases or obesity comprising administering the pharmaceutical composition to a subject in need of the same. The Viola Herba extract, or the extract of Viola Herba, Persicae Semen, Cinnamomi Ramulus, and Glycyrrhiza spp. of the present invention is shown to be effective in reducing body weight, body fat, total cholesterol in blood, and lowering blood pressure, and thus can be used for effective prevention or treatment of lipid-related cardiovascular diseases or obesity.
摘要翻译：本发明涉及一种药用或食品添加剂组合物，其中含有中草药提取物，中草药提取物，麝香，樟子松和甘草属。用于预防或治疗与脂质有关的心血管疾病或肥胖，以及用于治疗与脂质有关的心血管疾病或肥胖症的方法，其包括将药物组合物施用于需要其的受试者。中提琴草提取物，或中提琴草，柿子精，樟子松和甘草提取物。显示出在减轻体重，体脂，血液中的总胆固醇和降低血压方面是有效的，因此可用于有效预防或治疗与脂质有关的心血管疾病或肥胖症。

4. 发明申请

WO2010041836A2 METHOD OF DETECTING SKIN-COLORED AREA USING VARIABLE SKIN COLOR MODEL 审中-公开
标题翻译：使用变色肤色模型来检测肤色区域的方法
公开(公告)号：WO2010041836A2
公开(公告)日：2010-04-15
申请号：PCT/KR2009/005422
申请日：2009-09-23
申请人： KOREA INSTITUTE OF ORIENTAL MEDICINE , DO, Jun-Hyeong , KIM, Keun Ho , KIM, Jong Yeol
发明人： DO, Jun-Hyeong , KIM, Keun Ho , KIM, Jong Yeol
IPC分类号： G06T7/40
CPC分类号： G06K9/4652 , G06K9/00362 , G06T7/11 , G06T2207/10024 , G06T2207/30201
摘要： The present invention relates to a method of detecting a skin-colored area using a variable skin color model. In the method, an initial skin-colored area is extracted from an input image using a skin color model, the initial skin-colored area being repeatedly extracted by adjusting a threshold value, which is a criterion for the selection of a skin-colored area, until a ratio of size of the extracted skin-colored area to size of the entire input image becomes less than a predetermined value. A skin-colored area is extracted by applying the threshold value determined in the first stage to the skin color model, the skin color model being modified by analyzing characteristics of object regions and noise regions of the skin-colored area. The skin-colored area detection method can obtain a high skin-colored object detection rate and a high false alarm rate even under various lighting and background conditions.
摘要翻译：本发明涉及一种使用可变肤色模型来检测肤色区域的方法。在该方法中，使用肤色模型从输入图像中提取初始肤色区域，通过调整阈值来重复提取初始肤色区域，该阈值是用于选择肤色区域的标准，直到提取的肤色区域的大小与整个输入图像的大小的比率变得小于预定值为止。通过将在第一阶段中确定的阈值应用于肤色模型来提取肤色区域，通过分析肤色区域的对象区域和噪声区域的特征来修改肤色模型。即使在各种照明和背景条件下，肤色区域检测方法也可以获得高肤色物体检测率和高误报率。

5. 发明申请

WO2008111713A1 DIAGNOSIS SYSTEM OF DEFICIENT AND FORCEFUL PULSE 审中-公开
标题翻译：缺陷和有力脉搏诊断系统
公开(公告)号：WO2008111713A1
公开(公告)日：2008-09-18
申请号：PCT/KR2007/004748
申请日：2007-09-28
申请人： KOREA INSTITUTE OF ORIENTAL MEDICINE , KIM, Jong Yeol , LEE, Jeon , LEE, Yu Jung , LEE, Si Woo , KANG, Jaehwan , RYU, Hyunhee , LEE, Hae-Jung , CHOI, Eun-Ji
发明人： KIM, Jong Yeol , LEE, Jeon , LEE, Yu Jung , LEE, Si Woo , KANG, Jaehwan , RYU, Hyunhee , LEE, Hae-Jung , CHOI, Eun-Ji
IPC分类号： A61B5/02
CPC分类号： A61B5/024 , A61B5/4854 , A61B5/6824 , A61B2562/0247 , A61B2562/046 , G06F19/00
摘要： Disclosed herein is a system for diagnosing a deficient pulse and an forceful pulse. The system includes a pulse diagnotic device, a deficient pulse and forceful pulse determining device, and an output device. The pulse diagnotic device measures pulse condition information at an examinee's Cun (~\f~), Gu (H), and Chi (,R) pulse-taking locations on his or her wrist using one or more pulse-taking sensors. The deficient pulse and forceful pulse determining device is operably connected to the pulse diagnotic device, analyzes the pulse pressure information measured by the pulse diagnotic device, calculates a quantified deficiency/forceful coefficient, and determines whether a pulse of interest is a deficient pulse or an forceful pulse. The output device is connected to the determining device and displays results of the determination.
摘要翻译：本文公开了一种用于诊断缺陷脉冲和有力脉冲的系统。该系统包括脉冲诊断装置，缺陷脉冲和有力的脉冲确定装置，以及输出装置。脉冲诊断装置使用一个或多个脉冲采集传感器来测量他或她的手腕上的受检者Cun（〜\ f〜），Gu（H）和Chi（，R）脉搏取得位置的脉搏状况信息。脉冲和有力的脉冲确定装置可操作地连接到脉冲诊断装置，分析由脉冲诊断装置测量的脉搏压力信息，计算定量不足/有力系数，并确定感兴趣的脉冲是否是缺陷脉冲有力的脉搏输出设备连接到确定设备并显示确定的结果。

6. 发明申请

WO2004058284A1 ANTI-OBESITY INGRETIENTS FROM MEDICINAL PLANTS AND THEIR COMPOSITTION 审中-公开
标题翻译：药物植物的抗生素成分及其组成
公开(公告)号：WO2004058284A1
公开(公告)日：2004-07-15
申请号：PCT/KR2003/002852
申请日：2003-12-26
申请人： KOREA INSTITUTE OF ORIENTAL MEDICINE , SK CHEMICALS, CO., LTD. , YOON, Yoo, Sik , KIM, Sun, Hyoung , HAN, Chang-Kyun , CHOI, Wonrack , JEON, Hyo, Jin , IM, Guang-Jin , KIM, Yong, Hyuk , KUM, Do, Seung , KWAK, Wie-Jong
发明人： YOON, Yoo, Sik , KIM, Sun, Hyoung , HAN, Chang-Kyun , CHOI, Wonrack , JEON, Hyo, Jin , IM, Guang-Jin , KIM, Yong, Hyuk , KUM, Do, Seung , KWAK, Wie-Jong
IPC分类号： A61K35/78
CPC分类号： A61K36/17 , A23L33/105 , A23L33/30 , A23V2002/00 , A61K36/539 , A61K36/88 , A61K2300/00 , A23V2250/21 , A23V2250/70 , A23V2250/1638
摘要： Disclosed is a composition for preventing obesity comprising herbal medicines combined. In particular, the present invention relates to a composition for inhibiting and preventing obesity and various adult diseases associated with the same, which comprises a mixed extract from Ephedrae Herba, Scutellariae Radix and Typhae Pollen or the composition comprising the mixed extract described above together with at least one selected from the group consisting of Acorus gramineus Rhizome, Armeniacae Semen, Nelumbinus Folium and Polygalae Radix.
摘要翻译：公开了一种用于预防肥胖的组合物，其包括组合的草药。特别地，本发明涉及用于抑制和预防肥胖症和与此相关的各种成人疾病的组合物，其包含来自麻黄，黄芩和香蒲花粉的混合提取物或包含上述混合提取物以及在至少一种选自由禾本科禾本科，亚美尼亚精子，Nelumbinus Folium和Polygalae Radix组成的组。

7. 发明申请

WO2010002070A1 METHOD FOR GROUPING 3D MODELS TO CLASSIFY CONSTITUTION 审中-公开
标题翻译：将3D模型分类到分类法的方法
公开(公告)号：WO2010002070A1
公开(公告)日：2010-01-07
申请号：PCT/KR2008/005542
申请日：2008-09-19
申请人： KOREA INSTITUTE OF ORIENTAL MEDICINE , KIM, Keun Ho , DO, Jun-Hyeong , KIM, Jong Yeol
发明人： KIM, Keun Ho , DO, Jun-Hyeong , KIM, Jong Yeol
IPC分类号： G06T17/00
CPC分类号： G06K9/00221
摘要： Provided is a three-dimensional model classification method of classifying constitutions. The method includes correcting color values of a frontal image and one or more profile images to allow a color value of a reference color table in the images to equal a predetermined reference color value, through obtaining the frontal image and one or more profile images of a subject including the reference color table by a camera, the reference color table including one or more sub color regions, generating a three-dimensional geometric model of the subject by extracting feature point information from the frontal image and the profile image, matching the corresponding feature point information to extract spatial depth information, after removing the reference color table region from the frontal image and the profile image, and classifying a group of the three-dimensional geometric model of the subject by selecting a reference three- dimensional geometric model having a smallest sum of spatial displacements from the three-dimensional geometric model of the subject from a plurality of reference three-dimensional geometric models stored in the database and setting the group which the selected reference three-dimensional geometric model represents as the group where the three-dimensional geometric model of the subject belongs.
摘要翻译：提供了一种分类宪法的三维模型分类方法。该方法包括校正正面图像和一个或多个轮廓图像的颜色值，以通过获得正面图像和一个或多个轮廓图像来允许图像中的参考颜色表的颜色值等于预定参考颜色值对象包括通过相机的参考颜色表，参考颜色表包括一个或多个子颜色区域，通过从正面图像和轮廓图像中提取特征点信息来生成对象的三维几何模型，匹配相应的特征在从正面图像和轮廓图像中去除参考颜色表格区域之后提取空间深度信息的点信息，并且通过选择具有最小的参考三维几何模型的参考三维几何模型来对主体的三维几何模型进行分类来自多个对象的三维几何模型的空间位移的总和参考存储在数据库中的三维几何模型，并将所选择的参考三维几何模型所表示的组设置为主体的三维几何模型所属的组。

8. 发明申请

WO2006129898A1 A MASS SEPARATION METHOD OF MAGNOLOL FROM MAGNOLIAE CORTEX ORMAGNOLIAE RADIX 审中-公开
标题翻译：来自魔芋胶原蛋白的大分子量分离方法
公开(公告)号：WO2006129898A1
公开(公告)日：2006-12-07
申请号：PCT/KR2005/001914
申请日：2005-06-21
申请人： KOREA INSTITUTE OF ORIENTAL MEDICINE , KIM, JIN SOOK , LEE, YUN MI , JANG, DAE SIK
发明人： KIM, JIN SOOK , LEE, YUN MI , JANG, DAE SIK
IPC分类号： C07C37/82
CPC分类号： C07C37/82 , C07C37/004 , C07C37/685 , C07C37/84 , C07C39/21
摘要： The present invention related to method for the mass separation of magnolol from Magnoliae cortex or Magnoliae radix. The method comprises the steps of: 1) crushing Magnoliae cortex or Magnoliae radix, extracting the crushed material with organic solvent, adding n-hexane to the extract so as to obtain a n-hexane layer; 2) concentrating the n-hexane layer in a water bath at a temperature of 30-40 0C and a revolution speed of 40-200 RPM under reduced pressure so as to form a crude crystal; and 3) removing the n-hexane from the crude crystal, completely dissolving the crude crystal in chloroform, adding n-hexane to the n-hexane-containing solution, and leaving the solution to stand at room temperature so as to recrystallize the solution. In the method, a column chromatography step which is necessarily carried out in the general separation process is omitted so that separation process steps are reduced, leading to a saving in separation time. Also, expensive equipment is not required, leading a reduction in separation cost. Accordingly, the method is effective for the mass separation of expensive magnolol.
摘要翻译：本发明涉及厚朴与厚朴与木兰质量分离的方法。该方法包括以下步骤：1）粉碎玉兰大麦或木兰，用有机溶剂萃取粉碎物，向提取液中加入正己烷，得到正己烷层; 2）将正己烷层在30-40℃的温度和40-200rpm的转速下在水浴中浓缩，以形成粗晶体; 3）从粗结晶中除去正己烷，将粗结晶完全溶解在氯仿中，向正己烷溶液中加入正己烷，使溶液在室温下静置，使溶液重结晶。在该方法中，省略了在一般的分离过程中必须进行的柱色谱步骤，从而减少了分离工艺步骤，从而节省了分离时间。此外，不需要昂贵的设备，导致分离成本的降低。因此，该方法对于昂贵的厚朴酚的质量分离是有效的。

9. 发明申请

WO2005074963A1 COMPOSITION FOR PREVENTION AND TREATMENT OF DIABETIC COMPLICATION 审中-公开
标题翻译：用于预防和治疗糖尿病合并的组合物
公开(公告)号：WO2005074963A1
公开(公告)日：2005-08-18
申请号：PCT/KR2004/003554
申请日：2004-12-31
申请人： KOREA INSTITUTE OF ORIENTAL MEDICINE , KIM, Jin Sook , LEE, Sang Won , LEE, Yin Mi
发明人： KIM, Jin Sook , LEE, Sang Won , LEE, Yin Mi
IPC分类号： A61K35/78
CPC分类号： A61K36/575 , A23L33/105 , A61K36/47 , A61K36/484 , A61K36/488 , A61K2300/00
摘要： The present invention relates to a composition for the prevention and treatment of diabetic complications, which contains an extract obtained by: crushing and drying any one selected from Euphorbiae radix, gingered Magnolia bark, parched Puerariae radix and Glycyrrhizae radix; extracting the dried herbal material with alcohol or aqueous alcohol solution; filtering the extract; and concentrating the filtrate under reduced pressure. Alternatively, the composition contains a mixture of extracts from Euphorbiae radix, gingered Magnolia bark, parched Puerariae radix and Glycyrrhizae radix, the amount of each of the herbal extracts being 5-85% by weight based on 100% by weight of the herbal extract mixture. Alternatively, the composition contains magnolol obtained by: extracting Magnolia bark with aqueous 80% ethanol solution at ambient temperature for 24 hours; systematically separating the extract in the order of normal-hexane, ethyl acetate and normal-butanol; selecting the normal-hexane layer and separating the selected layer into pre-fractions by normal silica gel chromatography; comparing the pre-fractions with the standard form magnolol on TLC to determine a magnolol-enriched fraction; and separating magnolol from the magnolol-enriched fraction by silica gel column chromatography.
摘要翻译：本发明涉及一种预防和治疗糖尿病并发症的组合物，其含有通过以下方法获得的提取物：将来自大戟，，ered的木兰树皮，茯苓和甘草的任何一种粉碎和干燥; 用酒精或醇水溶液提取干草本材料; 过滤提取物; 并在减压下浓缩滤液。或者，组合物含有来自大戟根，ered ered的木兰皮，灼热葛根和甘草的提取物的混合物，基于100重量％的草药提取物混合物，每个草药提取物的量为5-85重量％。或者，组合物含有通过以下方式获得的厚朴酚：用80％乙醇水溶液在室温下提取木兰树皮24小时; 以正己烷，乙酸乙酯和正丁醇的顺序系统分离提取物; 选择正己烷层，并通过常规硅胶色谱法将所选择的层分离成预成分; 在TLC上比较预分数与标准形式的厚朴酚，以测定富含木酚的部分; 并通过硅胶柱色谱从厚朴酚组分中分离厚朴酚。

10. 发明申请

WO2011105657A1 COMPOSITION FOR THE PREVENTION OR TREATMENT OF ATOPIC DISEASES COMPRISING EXTRACT OF SOPHORAE TONKINENSIS RADIX AS ACTIVE INGREDIENT AND METHOD FOR PREPARATION OF THE SAME 审中-公开
标题翻译：用于预防或治疗包含作为活性成分的莨菪碱提取物的原发性疾病的组合物及其制备方法
公开(公告)号：WO2011105657A1
公开(公告)日：2011-09-01
申请号：PCT/KR2010/002055
申请日：2010-04-02
申请人： KOREA INSTITUTE OF ORIENTAL MEDICINE , SHIN, Hyun Kyoo , LEE, Ho Young , LEE, Jun Kyung , HA, Hye Kyung
发明人： SHIN, Hyun Kyoo , LEE, Ho Young , LEE, Jun Kyung , HA, Hye Kyung
IPC分类号： A61K36/489 , A61P17/00
CPC分类号： A61K36/489
摘要： The present invention relates to a composition for the prevention or treatment of atopic diseases, comprising an extract of sophorae tonkinensis radix as an active ingredient, and to a preparation method thereof. The sophorae tonkinensis radix extract of the present invention can be effectively used for the prevention or treatment of atopic diseases. Therefore, the sophorae tonkinensis radix extract can be applied to various fields including a pharmaceutical, food or cosmetic composition for the prevention or treatment of atopic diseases.
摘要翻译：本发明涉及用于预防或治疗特应性疾病的组合物及其制备方法，所述组合物包含檀香草提取物作为活性成分。本发明的苦参提取物可以有效地用于预防或治疗特应性疾病。因此，枸杞提取物可用于各种领域，包括用于预防或治疗特应性疾病的药物，食品或化妆品组合物。

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