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    • 3. 发明专利
    • Detection of vascular conditions using arterial pressure waveform data
    • 使用手术压力波形数据检测血管病变
    • JP2014158956A
    • 2014-09-04
    • JP2014092360
    • 2014-04-28
    • Edwards Lifesciences Corpエドワーズ ライフサイエンシーズ コーポレイションEdwards Lifesciences Corporation
    • HATIB FERASLUCHY D ROTELIUK
    • A61B5/0245A61B5/022A61B10/00
    • A61B5/021A61B5/02028A61B5/02108A61B5/412
    • PROBLEM TO BE SOLVED: To provide models for use in detection of vascular conditions using arterial pressure waveform data.SOLUTION: Multivariate statistical models for the detection of vascular conditions, methods for creating such multivariate statistical models 310, and methods for the detection of vascular condition in a patient using the multivariate statistical models are described. The models are created based on arterial pressure waveform data from a first group of patients that have experienced a particular vascular condition and a second group of patients that have not experienced the same vascular condition. The multivariate statistical models 310 are set up to provide different output values for each set of input data. Thus, when data from a patient under observation is input into the model, the relationship of the model output value to the established output values for the two groups upon which the model has been established indicates whether the patient is experiencing the vascular condition.
    • 要解决的问题:提供使用动脉压波形数据检测血管疾病的模型。解决方案:用于检测血管病变的多变量统计模型,创建这种多变量统计模型的方法310,以及检测血管病变的方法 在使用多变量统计模型的患者中进行了描述。 基于来自经历特定血管病变的第一组患者的动脉压波形数据和未经历相同血管病症的第二组患者创建模型。 多变量统计模型310被设置为为每组输入数据提供不同的输出值。 因此,当将来自待观察患者的数据输入到模型中时,模型输出值与已经建立模型的两组的建立的输出值的关系表示患者是否正在经历血管状况。
    • 8. 发明专利
    • Real-time measurement of ventricular stroke volume variation by continuous arterial pulse contour analysis
    • 通过连续脉冲波形分析实时测量静脉搏动量变化
    • JP2012011218A
    • 2012-01-19
    • JP2011196457
    • 2011-09-08
    • Edwards Lifesciences Corpエドワーズ ライフサイエンシーズ コーポレイションEdwards Lifesciences Corporation
    • HATIB FERASROTELIUK LUCHY
    • A61B5/0295A61B5/02A61B5/0205A61B5/029A61B5/08A61B5/1473
    • A61B5/02A61B5/02028A61B5/0205A61B5/021A61B5/02108A61B5/0215A61B5/029A61B5/0402A61B5/0816
    • PROBLEM TO BE SOLVED: To provide a real-time measurement of ventricular stroke volume variations by continuous arterial pulse contour analysis.SOLUTION: Ventricular stroke volume variation (SVV) is estimated as a function of the standard deviation of arterial blood pressure value measured over each of at least two cardiac cycles, preferably over each of the cardiac cycles in a computation interval covering a full respiratory cycle 325. In one embodiment, maximum and minimum standard deviation values are determined over the computation interval. SVV is then estimated proportional to the ratio of the difference between the maximum and minimum standard deviation values and the mean of the standard deviation values. In another embodiment, SVV is then estimated proportional to the ratio of the standard deviation of the standard deviation values and the mean standard deviation over the entire computation interval. A pre-processing arrangement for improving reliability of estimates of more general cardiac or hemodynamic parameters is also disclosed and involves smoothing with an approximating function, and sampling 313 and low-pass filtering 314 at an adjustable rate.
    • 要解决的问题:通过连续动脉脉冲轮廓分析提供心室搏动体积变化的实时测量。

      解决方案:心室搏动量变化(SVV)被估计为在至少两个心动周期中测量的动脉血压值的标准偏差的函数,优选地在覆盖全部的计算间隔中的每个心动周期 呼吸周期325.在一个实施例中,在计算间隔上确定最大和最小标准偏差值。 然后估计SVV与最大和最小标准偏差值之间的差值与标准偏差值的平均值成比例。 在另一个实施例中,然后SVV与标准偏差值的标准偏差与整个计算间隔的平均标准偏差之比成正比。 还公开了一种用于提高更一般的心脏或血液动力学参数的估计的可靠性的预处理装置,并且涉及用近似函数进行平滑,并且以可调整的速率进行采样313和低通滤波314。 版权所有(C)2012,JPO&INPIT

    • 10. 发明专利
    • Tape-reinforced blood vessel implant piece with external reinforcement and its manufacturing method
    • 具有外部加固的带状增强血管植入物及其制造方法
    • JP2007014803A
    • 2007-01-25
    • JP2006289276
    • 2006-10-24
    • Edwards Lifesciences Corpエドワーズ ライフサイエンシーズ コーポレイションEdwards Lifesciences Corporation
    • MCINTYRE JOHNSHANNON DONALDKUO CHRISMCCOLLAM CHRISPETERSON ROBERT
    • A61F2/06
    • A61F2/06Y10S623/901
    • PROBLEM TO BE SOLVED: To provide a novel tape-reinforced tubular blood vessel implant piece without occurrence of peeling or fraying out of a reinforcing tape from a tubular base implant piece.
      SOLUTION: A method herein provided comprises: a process for providing the tubular base implant piece formed of a stretched sintered fluoropolymer material; a process for providing a strip of the reinforced tape formed of a stretched sintered fluoropolymer film; a process for spirally winding the reinforced tape around the outer surface of the tubular base implant piece at the first spiral pitch; a process for getting the reinforced tape wound spirally adhering onto the tubular base implant piece; a process for providing an externally reinforcing member formed of a substantially non-elastic beading; a process for winding the externally reinforcing member spirally around the reinforced tape spirally wound at the second spiral pitch different from the first spiral pitch; and a process for getting the externally reinforcing member spirally wound adhering onto the reinforced tape spirally wound.
      COPYRIGHT: (C)2007,JPO&INPIT
    • 要解决的问题:提供一种新型的带状增强的管状血管植入物片,而不会从管状基底植入物件发生加强带的剥离或磨损。 解决方案:本文提供的方法包括:提供由拉伸烧结的含氟聚合物材料形成的管状基底植入件的方法; 提供由拉伸的烧结氟聚合物膜形成的增强带的条带的方法; 用于以所述第一螺旋节距螺旋地将所述加强带卷绕在所述管状基底植入件的外表面上的过程; 用于使所述加强带缠绕在所述管状基底植入件上的方法; 提供由基本上无弹性的珠饰形成的外部加强件的方法; 将外部加强部件螺旋地卷绕在与第一螺旋节距不同的第二螺旋节距螺旋卷绕的增强带上的过程; 以及将螺旋卷绕的外部加固构件附着在螺旋卷绕的增强带上的工序。 版权所有(C)2007,JPO&INPIT